Výsledky vyhľadávania - "Regeneration physiology"
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1
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Eur J Appl Physiol
European journal of applied physiology, vol. 125, no. 2, pp. 277-301Predmety: [SDV] Life Sciences [q-bio], 0301 basic medicine, 03 medical and health sciences, Invited Review, 0302 clinical medicine, [SDV]Life Sciences [q-bio], Humans, Muscle, Skeletal/physiology, Muscle, Skeletal/metabolism, Adaptation, Physiological/physiology, Epigenesis, Genetic, Animals, Regeneration/physiology, Hot Temperature, Cryotherapy, Exercise, Heat treatment, Protein synthesis, Resistance and endurance training, Skeletal muscle
Popis súboru: application/pdf
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2
Autori: a ďalší
Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-14 (2025)
Brorson, J, Lin, L, Wang, J, Bæk, A, Billeskov, T B, Thybo, F F, Just, J, Haskó, J, Ravn, C, Hansen, R L, Bue, M, Jørgensen, J O L, Luo, Y, Jessen, N & Farup, J 2025, 'Complementing muscle regeneration-fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle', Nature Communications, vol. 16, no. 1, 5233. https://doi.org/10.1038/s41467-025-60627-2Predmety: Regeneration/physiology, Male, Aged, 80 and over, Aging, Stem Cells/metabolism, Adipogenesis, Science, Article, Muscle, Skeletal/physiology, Phagocytosis, Monocytes/metabolism, Macrophages/metabolism, Humans, Female, Aged
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3
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Acta Neuropathol Commun
Acta Neuropathologica Communications, Vol 13, Iss 1, Pp 1-18 (2025)Predmety: Integrins, Sensory Receptor Cells, Genetic Vectors, Nerve Tissue Proteins/metabolism, Tenascin/metabolism, Nerve Tissue Proteins, Spinal Cord Injuries/pathology, Spinal cord injury, Nerve Regeneration/physiology, AAV vectors, Rats, Sprague-Dawley, Mice, Animals, Kindlin, Axon regeneration, RC346-429, Spinal Cord Injuries, Dependovirus/genetics, Sensory Receptor Cells/metabolism, kindlin, Animal, Research, axon regeneration, Sensory testing, sensory testing, Tenascin, Recovery of Function, Dependovirus, spinal cord injury, Axons, Recovery of Function/physiology, Nerve Regeneration, Rats, Disease Models, Animal, Disease Models, integrins, Female, Sprague-Dawley, Neurology. Diseases of the nervous system
Popis súboru: text/xml; application/pdf
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40317093
https://doaj.org/article/6ce7451ce7e34e2284c41a6800cf8d18
https://hdl.handle.net/20.500.11755/d943d55d-6840-4a40-b2c3-08b77573b4c5
https://pure.knaw.nl/portal/en/publications/d943d55d-6840-4a40-b2c3-08b77573b4c5
https://doi.org/10.1186/s40478-025-01995-0
https://hdl.handle.net/11104/0366327
https://www.repository.cam.ac.uk/handle/1810/383624
https://doi.org/10.1186/s40478-025-01995-0 -
4
Autori: a ďalší
Zdroj: Mol Neurodegener
Molecular Neurodegeneration, Vol 20, Iss 1, Pp 1-27 (2025)Predmety: Transcription factor combinations, Spinal/metabolism, Spinal Cord Injuries/metabolism, Promoter analysis, Kruppel-Like Transcription Factors, Axons/metabolism, Spinal cord injury, Nerve Regeneration/physiology, Rats, Sprague-Dawley, Ganglia, Spinal, Animals, Axon regeneration, RC346-429, Kruppel-Like Transcription Factors/genetics, Transcription factor over-expression, Spinal Cord Injuries, MEF2 Transcription Factors, RC952-954.6, AAV, Gene expression profiling, Axons, Nerve Regeneration, Rats, MEF2 Transcription Factors/metabolism, Geriatrics, Neuron-intrinsic, Ganglia, Female, Sprague-Dawley, Neurology. Diseases of the nervous system, Research Article
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39923113
https://doaj.org/article/3eee5663c2784c398e005f8199cf37a7
https://research.vu.nl/en/publications/742879e2-d01f-432f-84f9-5e7a7cb851a0
https://doi.org/10.1186/s13024-025-00805-4
https://hdl.handle.net/1871.1/742879e2-d01f-432f-84f9-5e7a7cb851a0 -
5
Autori: a ďalší
Zdroj: Cardiovasc Intervent Radiol
Arntz, P J W, Olthof, P B, Korenblik, R, Heil, J, Kazemier, G, van Delden, O M, Bennink, R J, Damink, S W M O, van Dam, R M, Schadde, E & Erdmann, J I 2024, 'Effect of Sarcopenia on the Increase in Liver Volume and Function After Portal Vein Embolization', CardioVascular and Interventional Radiology, vol. 47, no. 5, pp. 642-649. https://doi.org/10.1007/s00270-024-03676-2Predmety: Male, Sarcopenia, Portal Vein, Hepatobiliary scintigraphy, Female [MeSH], Liver Regeneration/physiology [MeSH], Clinical Investigation, Aged [MeSH], Liver function, Humans [MeSH], Embolization, Therapeutic/methods [MeSH], Portal Vein/diagnostic imaging [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Tomography, X-Ray Computed/methods [MeSH], Sarcopenia/diagnostic imaging [MeSH], Organ Size [MeSH], Male [MeSH], TIPS, Liver/diagnostic imaging [MeSH], Portal vein embolization, Organ Size, Middle Aged, Embolization, Therapeutic, Liver Regeneration, 03 medical and health sciences, 0302 clinical medicine, Liver, Humans, Female, Tomography, X-Ray Computed, Aged, Retrospective Studies
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38416177
https://pure.eur.nl/en/publications/86dd442e-af03-496d-86e2-45fe37f01ba5
https://doi.org/10.1007/s00270-024-03676-2
https://hdl.handle.net/11370/6b8f068f-b75b-48fc-8762-9783893cbb4d
https://research.rug.nl/en/publications/6b8f068f-b75b-48fc-8762-9783893cbb4d
https://doi.org/10.1007/s00270-024-03676-2
https://cris.maastrichtuniversity.nl/en/publications/07bea877-d67f-4d68-bdf6-78a73cabdff2
https://doi.org/10.1007/s00270-024-03676-2
https://research.vumc.nl/en/publications/b8146887-c457-40f6-b76d-e7677cbdcd95
https://repository.publisso.de/resource/frl:6518142 -
6
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Science
Predmety: Mammals, Regeneration/physiology, Sarcomeres, Myocytes, Cardiac/physiology, Heart, Sarcomeres/physiology, Zebrafish/physiology, Heart/physiology, Calcium/physiology, Journal Article, Animals, Regeneration, Calcium, Myocytes, Cardiac, Myocytes, Cardiac/physiology, Zebrafish, Cell Proliferation
Popis súboru: application/pdf
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37200435
https://pure.knaw.nl/portal/en/publications/d4319da0-77cc-4118-bc78-78bf6b66d01e
https://doi.org/10.1126/science.abo6718
https://hdl.handle.net/20.500.11755/d4319da0-77cc-4118-bc78-78bf6b66d01e
https://dspace.library.uu.nl/handle/1874/449256
https://pure.amsterdamumc.nl/en/publications/c3136b53-bf85-499f-a6ab-667d4738f58d
https://doi.org/10.1126/science.abo6718
https://hdl.handle.net/11577/3494689
https://doi.org/10.1126/SCIENCE.ABO6718
https://hdl.handle.net/1887/3656841 -
7
Autori: a ďalší
Zdroj: J Orthop Surg Res
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-11 (2024)
Journal of orthopaedic surgery and research 19, 527 (2024). doi:10.1186/s13018-024-05028-9Predmety: Osteogenesis/drug effects [MeSH], Osteoinductivity, Polyesters [MeSH], Bone Regeneration/drug effects [MeSH], Bone Regeneration/physiology [MeSH], Osteogenic differentiation, Scaffolds, Humans [MeSH], Cell Differentiation/drug effects [MeSH], Bone defects, Bone tissue engineering, Mesenchymal Stem Cells/drug effects [MeSH], Graphite/chemistry [MeSH], Bone and Bones/physiology [MeSH], Graphene, Tissue Scaffolds [MeSH], Cells, Cultured [MeSH], Tissue Engineering/methods [MeSH], Osteogenesis/physiology [MeSH], Research Article, Umbilical cord, Mesenchymal Stem Cells/physiology [MeSH], Bone Regeneration, Polyesters, Diseases of the musculoskeletal system, 02 engineering and technology, 01 natural sciences, Bone and Bones, Osteogenesis, Humans, Cells, Cultured, Orthopedic surgery, Tissue Engineering, Tissue Scaffolds, Mesenchymal Stem Cells, Cell Differentiation, 0104 chemical sciences, RC925-935, Graphite, 0210 nano-technology, RD701-811
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8
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: American Journal of Transplantation. 23:190-201
Predmety: Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha / metabolism, 0301 basic medicine, 2747 Transplantation, Molecular biology, Hepatectomy / adverse effects, Basic (laboratory) research/science, 610 Medicine & health, Carnitine / metabolism, Mice, 03 medical and health sciences, Liver / metabolism, Carnitine, 540 Chemistry, 2736 Pharmacology (medical), Animals, Hepatectomy, Hypoxia, Murine, 10038 Institute of Clinical Chemistry, 10217 Clinic for Visceral and Transplantation Surgery, 0303 health sciences, Liver (native) function/dysfunction, Tissue injury and repair, Liver transplantation/hepatology, Liver / surgery, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Lipids, Liver Regeneration, 3. Good health, Liver, Regenerative medicine, 2723 Immunology and Allergy, Liver Failure / surgery, Liver biology, Translational research/science, Liver Regeneration / physiology, Liver Failure
Popis súboru: application/pdf; ZORA_232446.pdf - application/pdf
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9
Autori: a ďalší
Zdroj: azizi, F, Ghasemi, R, EbrahimiBarough, S, Ardalan, M & Hadjighassem, M 2023, 'Effect of multifactorial therapeutic approach on axonal regeneration and cell viability in an in-vitro model of spinal-derived neural injury', Cell and Tissue Banking, vol. 24, no. 2, pp. 471–484 . https://doi.org/10.1007/s10561-022-10047-z
Predmety: Lipopolysaccharides, 0301 basic medicine, 0303 health sciences, Cell Survival, Lipopolysaccharide, Spinal cord injury, G-CSF, Lipopolysaccharides/pharmacology, Nerve Regeneration/physiology, Nerve Regeneration, 3. Good health, 03 medical and health sciences, In vitro, Spinal Cord Injuries/therapy, Spinal Injuries, Olfactory ensheathing cells, Humans, Combination therapy, Cells, Cultured, Spinal Cord Injuries
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36396867
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10
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Int J Implant Dent
Predmety: ddc:610, Bone Regeneration, 610 Medizin, Review, Alveolar Ridge Augmentation, Sinus floor elevation, Peri-implant defects, Particulate bovine bone substitute, Bone Regeneration/physiology [MeSH], Humans [MeSH], Bone Substitutes/therapeutic use [MeSH], Narrative review, Animals [MeSH], Alveolar Ridge Augmentation/methods [MeSH], Ridge preservation, Cattle [MeSH], Oral regeneration, 3. Good health, 610 Medical sciences, Bone Substitutes, Animals, Humans, Cattle
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38801622
https://repository.publisso.de/resource/frl:6490758 -
11
Autori: a ďalší
Zdroj: Journal of visualized experiments : JoVE. (207)
Predmety: scale, Regeneration/physiology, Animal Scales, osteoblast, Osteoclasts, Animals, Regeneration, zebrafish, BONE, Zebrafish
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38767351
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12
Autori:
Zdroj: Int J Implant Dent
Predmety: Male, Adult, Immediate Dental Implant Loading, Bone Transplantation, Bone Regeneration, Research, Alveolar Bone Loss, Female [MeSH], Bone grafting, Aged [MeSH], Alveolar Bone Loss/surgery [MeSH], Bone Regeneration/physiology [MeSH], Adult [MeSH], Flapless implant surgery, Humans [MeSH], Bone defects, Retrospective Studies [MeSH], Bone Transplantation/methods [MeSH], Middle Aged [MeSH], Bone regeneration, Immediate implants, Connective Tissue/transplantation [MeSH], Male [MeSH], Autogenous bone graft, Immediate Dental Implant Loading/methods [MeSH], Alveolar Ridge Augmentation/methods [MeSH], Soft tissue grafting, Alveolar Ridge Augmentation, Middle Aged, 03 medical and health sciences, 0302 clinical medicine, Connective Tissue, Humans, Female, Retrospective Studies, Aged
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38760582
https://repository.publisso.de/resource/frl:6501020 -
13
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Br J Surg
The British journal of surgery, Vol. 111, no.4 (2024)Predmety: Male, Adult, Liver Regeneration/physiology, Medizin, Hepatic Veins, Sciences de la santé humaine, chirurgie, Liver Neoplasms/surgery, Embolization, Liver Neoplasms/therapy mortality surgery, cancer, Humans, Hepatectomy, Human health sciences, Chirurgie, 10. No inequality, Retrospective Studies, Aged, 2. Zero hunger, Liver Neoplasms/mortality, Portal Vein, Liver Neoplasms, Radiologie, médecine & imagerie nucléaire, Liver Neoplasms/therapy, Middle Aged, Embolization, Therapeutic, Survival Analysis, Liver Regeneration, 3. Good health, Survival Rate, Surgery, Original Article, Female, Embolization, Therapeutic/methods, Hepatectomy/methods, Foie, Therapeutic/methods, Radiology, nuclear medicine & imaging
Popis súboru: text
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38662462
https://cris.maastrichtuniversity.nl/en/publications/2a8dfa04-1f9c-45db-b2f7-9327b4ddf484
https://doi.org/10.1093/bjs/znae087
https://hdl.handle.net/2078.1/287132
https://www.ncbi.nlm.nih.gov/pubmed/38662462
https://doi.org/10.1093/bjs/znae087
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85191501825 -
14
Autori: a ďalší
Zdroj: British Journal of Surgery, 111 (4) (2024-04-03)
Predmety: Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Survival Rate, Survival Analysis, Adult, Portal Vein, Liver Neoplasms/therapy, Liver Neoplasms/mortality, Liver Neoplasms/surgery, Embolization, Therapeutic/methods, Liver Regeneration/physiology, Hepatic Veins, Hepatectomy/methods, Foie, cancer, chirurgie, Human health sciences, Surgery, Radiology, nuclear medicine & imaging, Sciences de la santé humaine, Chirurgie, Radiologie, médecine & imagerie nucléaire
Relation: https://academic.oup.com/bjs/article-pdf/111/4/znae087/57332711/znae087.pdf; urn:issn:0007-1323; urn:issn:1365-2168
Prístupová URL adresa: https://orbi.uliege.be/handle/2268/316854
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15
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Nature. 591:281-287
Predmety: Regeneration/physiology, Male, 0301 basic medicine, Receptors, CCR5, Nicotinamide Phosphoribosyltransferase/genetics, Inbred C57BL, Myoblasts, Mice, 03 medical and health sciences, Receptors, Animals, Humans, Regeneration, PAX7 Transcription Factor/metabolism, RNA-Seq, Stem Cell Niche, General, Muscle, Skeletal, Nicotinamide Phosphoribosyltransferase, Zebrafish, Cell Proliferation, 0303 health sciences, Animal, Macrophages, Macrophages/cytology, PAX7 Transcription Factor, Matrix Metalloproteinase 9/genetics, CCR5/genetics, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, Matrix Metalloproteinase 9, Skeletal/cytology, Disease Models, Muscle, Zebrafish/immunology, Single-Cell Analysis, Myoblasts/cytology
Popis súboru: application/pdf
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33568815
https://pure.knaw.nl/portal/en/publications/c22f6e03-989d-4750-a4db-fa3c8c083395
https://hdl.handle.net/20.500.11755/c22f6e03-989d-4750-a4db-fa3c8c083395
https://doi.org/10.1038/s41586-021-03199-7
https://www.nature.com/articles/s41586-021-03199-7.pdf
https://www.scilit.net/article/3faf39d56e15ef2bc1d3f194faf25582
https://www.nature.com/articles/s41586-021-03199-7
https://econpapers.repec.org/article/natnature/v_3a591_3ay_3a2021_3ai_3a7849_3ad_3a10.1038_5fs41586-021-03199-7.htm
https://www.ncbi.nlm.nih.gov/pubmed/33568815
https://research.monash.edu/en/publications/macrophages-provide-a-transient-muscle-stem-cell-niche-via-nampt-
https://dspace.library.uu.nl/handle/1874/445789 -
16
Autori: a ďalší
Zdroj: Journal of Composites Science. 8:408
Predmety: Morphology, Blowing agents, Polymers, Hyaluronic acid, Effectiveness, Mechanical properties, Investigations, and Tissue Engineering, Molecular weight, Central composite design, Permeability, Scaffold, Degradation, Biopolymers, Estimators, Methods, Parameter estimation, Tissue engineering, Aqueous solutions, Scaffolds, Agitation, Diagnostic and Therapeutic Techniques and Equipment, Crosslinking, Applied Statistics, Sodium, Temperature, Polymer and Organic Materials, Molecular, Laser microscopy, Modulus of elasticity, Regeneration (physiology), Composite materials, Extracellular matrix, Analytical, 3-D printers, Elastin, Error analysis, Statistical analysis, Freeze drying, Pore size, Gelatin, Biocompatibility, Cellular, Production processes, Cooling, Porosity, Foaming
Popis súboru: application/pdf
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17
Autori: a ďalší
Zdroj: Nat Commun
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)Predmety: Male, Central Nervous System, NF-E2-Related Factor 2, Science, Central Nervous System/metabolism, Astrocytes/metabolism, Nerve Regeneration/physiology, Article, Cholesterol/metabolism, Mice, name=General Biochemistry,Genetics and Molecular Biology, Animals, Humans, Myelin Sheath, Myelin Sheath/metabolism, 3. Good health, Nerve Regeneration, Oligodendroglia, Oligodendroglia/metabolism, Cholesterol, name=General Physics and Astronomy, Astrocytes, NF-E2-Related Factor 2/genetics, name=General Chemistry
Popis súboru: application/pdf
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18
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Cell Death Differ
Predmety: Regeneration/physiology, Adult, 0301 basic medicine, 0303 health sciences, Research Support, Non-U.S. Gov't, Epithelial Cells, YAP-Signaling Proteins, Review, Review Article, Epithelial Cells/metabolism, 3. Good health, Intestines, Organoids, 03 medical and health sciences, Journal Article, Organoids/cytology, Animals, Homeostasis, Humans, Regeneration, Intestinal Mucosa, Wnt Signaling Pathway, Intestinal Mucosa/metabolism, Intestines/cytology
Popis súboru: application/pdf
Prístupová URL adresa: https://www.nature.com/articles/s41418-020-00665-z.pdf
https://pubmed.ncbi.nlm.nih.gov/33208888
https://www.nature.com/articles/s41418-020-00665-z
https://www.scilit.net/article/88e5ba44119d22ae227373bd05d0e12f
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852609
https://www.nature.com/articles/s41418-020-00665-z.pdf
https://europepmc.org/article/PMC/PMC7852609
https://pubmed.ncbi.nlm.nih.gov/33208888/
https://dspace.library.uu.nl/handle/1874/443288 -
19
Autori: a ďalší
Prispievatelia: a ďalší
Zdroj: Cell Mol Neurobiol
Predmety: Neurons, 0301 basic medicine, ddc:610, 0303 health sciences, PTEN Phosphohydrolase, Pyramidal Tracts, 610 Medizin, Recovery of Function, Axons, Nerve Regeneration, 3. Good health, Mice, Inbred C57BL, 03 medical and health sciences, 610 Medical sciences, Animals, Humans, Spinal Cord Injuries, Spinal Cord Injuries/therapy [MeSH], Mice, Inbred C57BL [MeSH], Spinal cord injury, Recovery of Function/physiology [MeSH], Humans [MeSH], Neurons/metabolism [MeSH], Pyramidal Tracts/drug effects [MeSH], Animals [MeSH], Axons/metabolism [MeSH], PTEN Phosphohydrolase/pharmacology [MeSH], Nerve Regeneration/drug effects [MeSH], PTEN Phosphohydrolase/metabolism [MeSH], Corticospinal tract, Pyramidal Tracts/physiology [MeSH], Interleukin-4, Nerve Regeneration/physiology [MeSH], Spinal Cord Injuries/metabolism [MeSH], Regeneration, Original Research, Growth-promoting treatment, Recovery of Function/drug effects [MeSH]
Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s10571-020-00820-7.pdf
https://pubmed.ncbi.nlm.nih.gov/32172457
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497511
https://europepmc.org/article/MED/32172457
https://link.springer.com/content/pdf/10.1007/s10571-020-00820-7.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497511
https://link.springer.com/article/10.1007/s10571-020-00820-7
https://link.springer.com/article/10.1007/s10571-020-00820-7?error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&code=46814d91-0d7e-4804-89a5-56b4853ba3bb&code=7eae5d8f-8302-440c-b1cd-40b9c259bca3&code=56f7aff8-aa4b-4fff-b29d-04b43cbe93c1&code=47bb823c-fa81-4956-889b-0f03acf972b5&code=aa325dcf-c962-45ba-9a9e-da209ef52a05
https://repository.publisso.de/resource/frl:6468252 -
20
Autori: a ďalší
Zdroj: International journal of molecular sciences, vol. 24, no. 9, pp. 7800
Predmety: Humans, Animals, Rabbits, Dogs, Swine, Tissue Engineering, Schwann Cells/physiology, Peripheral Nervous System Diseases, Mesenchymal Stem Cells, Stem Cells, Trauma, Nervous System, Nerve Regeneration/physiology, Peripheral Nerve Injuries/therapy, Sciatic Nerve/injuries, Schwann cells, cell therapy, growth factors, large animal models, nerve guidance conduit, nerve injury, nerve regeneration
Popis súboru: application/pdf
Relation: info:eu-repo/semantics/altIdentifier/pmid/37175506; info:eu-repo/semantics/altIdentifier/eissn/1422-0067; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_D7D4C78105E26; https://serval.unil.ch/notice/serval:BIB_D7D4C78105E2; https://serval.unil.ch/resource/serval:BIB_D7D4C78105E2.P001/REF.pdf
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