Search Results - "Receptor-CD3 Complex"

Characterization of CD3+ T Lymphocytes in Human Coronary Thrombi with ST-segment Elevation Myocardial Infarction.

Authors: Gu M Xia N Zhang S et al.

Source: Thrombosis and haemostasis [Thromb Haemost] 2025 Jul; Vol. 125 (7), pp. 697-712. Date of Electronic Publication: 2024 Nov 07.

Publication Type: Journal Article

Journal Info: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE

MeSH Terms: ST Elevation Myocardial Infarction*/immunology , Coronary Thrombosis*/immunology , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Receptor-CD3 Complex, Antigen, T-Cell*/metabolism, Humans ; Male ; Female ; Middle Aged ; Single-Cell Gene Expression Analysis ; Case-Control Studies

In situ cell-surface conformation of the TCR-CD3 signaling complex.

Authors: Natarajan A Velmurugu Y Becerra Flores M et al.

Source: EMBO reports [EMBO Rep] 2024 Dec; Vol. 25 (12), pp. 5719-5742. Date of Electronic Publication: 2024 Nov 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH Terms: Signal Transduction* , CD3 Complex*/chemistry , CD3 Complex*/metabolism , Receptor-CD3 Complex, Antigen, T-Cell*/chemistry , Receptor-CD3 Complex, Antigen, T-Cell*/metabolism , Receptor-CD3 Complex, Antigen, T-Cell*/immunology, Humans ; Receptors, Antigen, T-Cell, alpha-beta/chemistry ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Protein Conformation ; Cell Membrane/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Cholesterol/metabolism ; Cholesterol/chemistry ; Protein Binding ; Receptors, Antigen, T-Cell/metabolism ; Receptors, Antigen, T-Cell/chemistry ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Models, Molecular ; Cross-Linking Reagents/chemistry

Key links in the physiological regulation of the immune system and disease induction: T cell receptor -CD3 complex.

Authors: Liu D Hu X Chen Z et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2024 Sep; Vol. 227, pp. 116441. Date of Electronic Publication: 2024 Jul 17.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Receptor-CD3 Complex, Antigen, T-Cell*/immunology , Receptor-CD3 Complex, Antigen, T-Cell*/metabolism, Humans ; Animals ; CD3 Complex/immunology ; CD3 Complex/metabolism ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Immune System/immunology ; Immune System/metabolism ; Signal Transduction/physiology ; Signal Transduction/immunology ; Immune System Diseases/immunology ; Immune System Diseases/metabolism

Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.

Authors: Chen Y Zhu Y Li X et al.

Source: Molecular cell [Mol Cell] 2022 Apr 07; Vol. 82 (7), pp. 1278-1287.e5. Date of Electronic Publication: 2022 Mar 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

MeSH Terms: Receptor-CD3 Complex, Antigen, T-Cell*/genetics , Receptor-CD3 Complex, Antigen, T-Cell*/metabolism , T-Lymphocytes*/metabolism, CD3 Complex/genetics ; CD3 Complex/metabolism ; Cholesterol/metabolism ; Cryoelectron Microscopy ; Humans ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism

Rigid crosslinking of the CD3 complex leads to superior T cell stimulation.

Authors: Nelson AD Wang L Laffey KG et al.

Source: Frontiers in immunology [Front Immunol] 2024 Aug 30; Vol. 15, pp. 1434463. Date of Electronic Publication: 2024 Aug 30 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: CD3 Complex*/immunology , CD3 Complex*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Immunoglobulin Fab Fragments*/immunology , Immunoglobulin Fab Fragments*/metabolism , Immunoglobulin Fab Fragments*/chemistry , Lymphocyte Activation*/immunology, Humans ; Animals ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Protein Binding ; Molecular Dynamics Simulation ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; Receptor-CD3 Complex, Antigen, T-Cell/metabolism ; Mice ; Antibodies, Monoclonal/immunology ; Signal Transduction ; Binding Sites

The T cell receptor displays lateral signal propagation involving non-engaged receptors.

Authors: Nieves DJ Pandzic E Gunasinghe SD et al.

Source: Nanoscale [Nanoscale] 2022 Mar 07; Vol. 14 (9), pp. 3513-3526. Date of Electronic Publication: 2022 Mar 07.

Publication Type: Journal Article

Journal Info: Publisher: RSC Pub Country of Publication: England NLM ID: 101525249 Publication Model: Electronic Cited Medium: Internet ISSN: 2040-3372 (Electronic) Linking ISSN: 20403364 NLM ISO Abbreviation: Nanoscale Subsets: MEDLINE

MeSH Terms: Receptor-CD3 Complex, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/metabolism, Phosphorylation ; Signal Transduction ; T-Lymphocytes/metabolism

The Full Model of the pMHC-TCR-CD3 Complex: A Structural and Dynamical Characterization of Bound and Unbound States.

Authors: Alba J D'Abramo M

Source: Cells [Cells] 2022 Feb 14; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Major Histocompatibility Complex* , Receptor-CD3 Complex, Antigen, T-Cell*/metabolism, CD3 Complex/metabolism ; Peptides/metabolism ; Protein Binding ; Receptors, Antigen, T-Cell/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/chemistry

Multi-scale simulations of the T cell receptor reveal its lipid interactions, dynamics and the arrangement of its cytoplasmic region.

Authors: Prakaash D Cook GP Acuto O et al.

Source: PLoS computational biology [PLoS Comput Biol] 2021 Jul 19; Vol. 17 (7), pp. e1009232. Date of Electronic Publication: 2021 Jul 19 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH Terms: Models, Molecular*, Receptor-CD3 Complex, Antigen, T-Cell/*chemistry , Receptor-CD3 Complex, Antigen, T-Cell/*metabolism, Computational Biology ; Computer Simulation ; Cryoelectron Microscopy ; Cytoplasm/chemistry ; Cytoplasm/metabolism ; Humans ; Lymphocyte Activation ; Membrane Lipids/chemistry ; Membrane Lipids/metabolism ; Molecular Dynamics Simulation ; Protein Conformation ; Protein Interaction Domains and Motifs ; Receptor-CD3 Complex, Antigen, T-Cell/ultrastructure ; Static Electricity ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism

Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity.

Authors: Adam K Lipatova Z Abdul Ghafoor Raja M et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 Jul 01; Vol. 213 (1), pp. 7-13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

MeSH Terms: Lymphocyte Activation Gene 3 Protein* , Antigens, CD*/immunology , Antigens, CD*/metabolism , Antigens, CD*/genetics , Protein Multimerization* , CD8-Positive T-Lymphocytes*/immunology, Animals ; Mice ; Melanoma, Experimental/immunology ; Mice, Inbred C57BL ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; CD3 Complex/immunology ; Humans ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Lymphocyte Activation/immunology ; Protein Binding

Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function.

Authors: Degirmencay A Thomas S Holler A et al.

Source: Frontiers in immunology [Front Immunol] 2024 May 30; Vol. 15, pp. 1386132. Date of Electronic Publication: 2024 May 30 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: CD3 Complex*/immunology , CD3 Complex*/pharmacology , Receptors, Antigen, T-Cell*/immunology , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/genetics , T-Lymphocytes*/drug effects , T-Lymphocytes*/immunology, Humans ; HEK293 Cells ; Lymphocyte Activation/immunology ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; Receptor-CD3 Complex, Antigen, T-Cell/metabolism ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/immunology

Phospho-mimetic CD3ε variants prevent TCR and CAR signaling.

Authors: Woessner NM Brandl SM Hartmann S et al.

Source: Frontiers in immunology [Front Immunol] 2024 May 08; Vol. 15, pp. 1392933. Date of Electronic Publication: 2024 May 08 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH Terms: CD3 Complex*/metabolism , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/immunology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Signal Transduction*/genetics, Humans ; Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; HEK293 Cells ; Immunoreceptor Tyrosine-Based Activation Motif ; Jurkat Cells ; Lymphocyte Activation/immunology ; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/metabolism ; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/genetics ; Phosphorylation ; Protein Binding ; Receptor-CD3 Complex, Antigen, T-Cell/metabolism ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; ZAP-70 Protein-Tyrosine Kinase/metabolism ; ZAP-70 Protein-Tyrosine Kinase/genetics

CD137 (4-1BB) costimulation of CD8 ⁺ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation.

Authors: Otano I Azpilikueta A Glez-Vaz J et al.

Source: Nature communications [Nat Commun] 2021 Dec 15; Vol. 12 (1), pp. 7296. Date of Electronic Publication: 2021 Dec 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: CD3 Complex/*immunology , CD8-Positive T-Lymphocytes/*immunology , Receptor-CD3 Complex, Antigen, T-Cell/*immunology , Tumor Necrosis Factor Receptor Superfamily, Member 9/*immunology, Animals ; CD3 Complex/genetics ; Cell Proliferation ; Cytokines/genetics ; Cytokines/immunology ; Humans ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Tumor Necrosis Factor Receptor Superfamily, Member 9/genetics

Structural variability and concerted motions of the T cell receptor - CD3 complex.

Authors: Pandey PR Różycki B Lipowsky R et al.

Source: ELife [Elife] 2021 Sep 07; Vol. 10. Date of Electronic Publication: 2021 Sep 07.

Publication Type: Journal Article; Video-Audio Media

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH Terms: CD3 Complex/*metabolism , Cell Membrane/*metabolism , Receptor-CD3 Complex, Antigen, T-Cell/*metabolism , Receptors, Antigen, T-Cell, alpha-beta/*metabolism , T-Lymphocytes/*metabolism, CD3 Complex/ultrastructure ; Cell Membrane/ultrastructure ; Cryoelectron Microscopy ; Humans ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation, alpha-Helical ; Receptor-CD3 Complex, Antigen, T-Cell/ultrastructure ; Receptors, Antigen, T-Cell, alpha-beta/ultrastructure ; Structure-Activity Relationship ; T-Lymphocytes/immunology ; T-Lymphocytes/ultrastructure

Ultrasmall silica nanoparticles directly ligate the T cell receptor complex.

Authors: Vis B Hewitt RE Monie TP et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 07; Vol. 117 (1), pp. 285-291. Date of Electronic Publication: 2019 Dec 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH Terms: Lymphocyte Activation/*drug effects , Nanoparticles/*chemistry , Receptor-CD3 Complex, Antigen, T-Cell/*drug effects , Receptor-CD3 Complex, Antigen, T-Cell/*metabolism , Silicon Dioxide/*chemistry , Silicon Dioxide/*pharmacology, CD28 Antigens/metabolism ; CD3 Complex/chemistry ; CD3 Complex/drug effects ; Cell Proliferation/drug effects ; Humans ; Interleukin-2/metabolism ; Models, Molecular ; Phosphorylation ; Receptor-CD3 Complex, Antigen, T-Cell/chemistry ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Signal Transduction/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism

The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions.

Authors: Lee MS Tuohy PJ Kim CY et al.

Source: ELife [Elife] 2024 Apr 19; Vol. 12. Date of Electronic Publication: 2024 Apr 19.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH Terms: Lymphocyte Specific Protein Tyrosine Kinase p56(lck)*/genetics , Lymphocyte Specific Protein Tyrosine Kinase p56(lck)*/metabolism , Placenta*/metabolism, Pregnancy ; Animals ; Female ; Signal Transduction/genetics ; Receptors, Antigen, T-Cell/metabolism ; Receptor-CD3 Complex, Antigen, T-Cell/metabolism ; Phosphorylation ; CD4 Antigens ; Mammals/metabolism

A scoring system for the electrostatic complementarities of T-cell receptors and cancer-mutant amino acids: multi-cancer analyses of associated survival rates.

Authors: Chobrutskiy BI Yeagley M Diviney A et al.

Source: Immunology [Immunology] 2020 Apr; Vol. 159 (4), pp. 373-383. Date of Electronic Publication: 2020 Jan 21.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

MeSH Terms: Algorithms*, Antigens, Neoplasm/*chemistry , Breast Neoplasms/*genetics , Complementarity Determining Regions/*chemistry , Lung Neoplasms/*genetics , Receptor-CD3 Complex, Antigen, T-Cell/*chemistry , Skin Neoplasms/*genetics, Amino Acid Sequence ; Amino Acids ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/immunology ; Binding Sites ; Breast Neoplasms/diagnosis ; Breast Neoplasms/immunology ; Breast Neoplasms/mortality ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/immunology ; Exome ; Female ; Gene Expression ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/immunology ; Lung Neoplasms/mortality ; Male ; Mutation ; Prognosis ; Protein Binding ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; Research Design ; Skin Neoplasms/diagnosis ; Skin Neoplasms/immunology ; Skin Neoplasms/mortality ; Static Electricity ; Survival Rate ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology

Actin polymerization regulates recruitment of Nck to CD3ε upon T-cell receptor triggering.

Authors: Wipa P Paensuwan P Ngoenkam J et al.

Source: Immunology [Immunology] 2020 Mar; Vol. 159 (3), pp. 298-308. Date of Electronic Publication: 2019 Nov 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

MeSH Terms: Lymphocyte Activation*/drug effects, Actin Cytoskeleton/*metabolism , Actins/*metabolism , Adaptor Proteins, Signal Transducing/*metabolism , CD3 Complex/*metabolism , Oncogene Proteins/*metabolism , Receptor-CD3 Complex, Antigen, T-Cell/*metabolism , T-Lymphocytes/*enzymology, Actin Cytoskeleton/immunology ; Actins/immunology ; Adaptor Proteins, Signal Transducing/genetics ; CD3 Complex/immunology ; Cytochalasin D/pharmacology ; Humans ; Jurkat Cells ; Oncogene Proteins/genetics ; Phosphorylation ; Polymerization ; Protein Binding ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Receptor-CD3 Complex, Antigen, T-Cell/immunology ; Signal Transduction ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; Time Factors ; ZAP-70 Protein-Tyrosine Kinase/metabolism

Experimentally Guided Computational Methods Yield Highly Accurate Insights into Transmembrane Interactions within the T Cell Receptor Complex.

Authors: Ramesh S Park S Call MJ et al.

Source: The journal of physical chemistry. B [J Phys Chem B] 2020 Nov 19; Vol. 124 (46), pp. 10303-10310. Date of Electronic Publication: 2020 Oct 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

MeSH Terms: Cell Membrane* , Receptor-CD3 Complex, Antigen, T-Cell*, Humans ; Protein Conformation

Predicting antigen specificity of single T cells based on TCR CDR3 regions.

Authors: Fischer DS Wu Y Schubert B et al.

Source: Molecular systems biology [Mol Syst Biol] 2020 Aug; Vol. 16 (8), pp. e9416.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

MeSH Terms: Computational Biology/*methods , Histocompatibility Antigens/*metabolism , Receptor-CD3 Complex, Antigen, T-Cell/*metabolism , Single-Cell Analysis/*methods , T-Lymphocytes/*immunology, Amino Acid Sequence ; Animals ; Deep Learning ; Histocompatibility Antigens/genetics ; Humans ; Receptor-CD3 Complex, Antigen, T-Cell/genetics ; Sequence Analysis, RNA ; Supervised Machine Learning

Atomic-resolution view of complete TCR-CD3 revealed.

Authors: Chai J; Institute of Biochemistry, University of Cologne, 50829, Cologne, Germany. jchai@uni-koeln.de.

Source: Protein & cell [Protein Cell] 2020 Mar; Vol. 11 (3), pp. 158-160.

Publication Type: Journal Article; Comment

Journal Info: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 101532368 Publication Model: Print Cited Medium: Internet ISSN: 1674-8018 (Electronic) Linking ISSN: 1674800X NLM ISO Abbreviation: Protein Cell Subsets: MEDLINE

MeSH Terms: Receptor-CD3 Complex, Antigen, T-Cell*, CD3 Complex