Výsledky vyhledávání - "Receptor Activity-Modifying Protein 3"

Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3.

Autoři: Carvas AO Leuthardt A Kulka P a další

Zdroj: EBioMedicine [EBioMedicine] 2025 Aug; Vol. 118, pp. 105836. Date of Electronic Publication: 2025 Jul 03.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

Výrazy ze slovníku MeSH: Body Weight*/drug effects , Brain*/metabolism , Brain*/drug effects , Islet Amyloid Polypeptide*/pharmacology , Receptors, Islet Amyloid Polypeptide*/metabolism , Receptors, Islet Amyloid Polypeptide*/genetics , Receptor Activity-Modifying Protein 3*/genetics , Receptor Activity-Modifying Protein 3*/metabolism, Animals ; Mice ; Mice, Knockout ; Male ; Receptor Activity-Modifying Protein 1/genetics ; Receptor Activity-Modifying Protein 1/metabolism ; Calcitonin/pharmacology ; Receptors, Calcitonin/metabolism ; Diet, High-Fat ; Obesity/drug therapy ; Obesity/metabolism ; Obesity/etiology

Amylin receptor subunit interactions are modulated by agonists and determine signaling.

Autoři: Gostynska SE Karim JA Ford BE a další

Zdroj: Science signaling [Sci Signal] 2025 Aug 19; Vol. 18 (900), pp. eadt8127. Date of Electronic Publication: 2025 Aug 19.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

Výrazy ze slovníku MeSH: Signal Transduction*/drug effects , Receptors, Islet Amyloid Polypeptide*/metabolism , Receptors, Islet Amyloid Polypeptide*/genetics , Receptors, Islet Amyloid Polypeptide*/chemistry , Amylin Receptor Agonists*/pharmacology, Humans ; Animals ; Rats ; HEK293 Cells ; Cyclic AMP/metabolism ; Receptors, Calcitonin/metabolism ; Receptors, Calcitonin/genetics ; Receptor Activity-Modifying Protein 1/metabolism ; Receptor Activity-Modifying Protein 1/genetics ; Islet Amyloid Polypeptide/metabolism ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Protein Subunits/metabolism ; Protein Binding ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 2/genetics ; Protein Multimerization

Differential expression of components of the CGRP-receptor family in human coronary and human middle meningeal arteries: functional implications.

Autoři: de Vries T Schutter D van den Bogaerdt A a další

Zdroj: The journal of headache and pain [J Headache Pain] 2024 Oct 10; Vol. 25 (1), pp. 176. Date of Electronic Publication: 2024 Oct 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE

Výrazy ze slovníku MeSH: Meningeal Arteries*/drug effects , Meningeal Arteries*/metabolism , Adrenomedullin*/metabolism , Adrenomedullin*/pharmacology , Adrenomedullin*/genetics , Receptors, Calcitonin Gene-Related Peptide*/metabolism , Coronary Vessels*/drug effects , Coronary Vessels*/metabolism , Calcitonin Receptor-Like Protein*/metabolism , Calcitonin Receptor-Like Protein*/genetics, Humans ; Middle Aged ; Male ; Female ; Receptor Activity-Modifying Protein 1/metabolism ; Receptor Activity-Modifying Protein 1/genetics ; Calcitonin Gene-Related Peptide/metabolism ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 2/genetics ; Vasodilation/drug effects ; Vasodilation/physiology ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Peptide Hormones

Neuropeptide signalling orchestrates T cell differentiation.

Autoři: Hou Y Sun L LaFleur MW a další

Zdroj: Nature [Nature] 2024 Nov; Vol. 635 (8038), pp. 444-452. Date of Electronic Publication: 2024 Oct 16.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Výrazy ze slovníku MeSH: Calcitonin Gene-Related Peptide*/metabolism , Cell Differentiation* , Signal Transduction* , Th1 Cells*/immunology , Th1 Cells*/cytology , Th1 Cells*/metabolism , Th2 Cells*/immunology , Th2 Cells*/cytology , Th2 Cells*/metabolism, Animals ; Female ; Male ; Mice ; Activating Transcription Factor 3/metabolism ; Calcitonin Receptor-Like Protein/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Mice, Inbred C57BL ; Receptor Activity-Modifying Protein 3/metabolism ; STAT1 Transcription Factor/metabolism

Receptor activity-modifying proteins of adrenomedullin (RAMP2/3): Roles in the pathogenesis of ARDS.

Autoři: Kasahara T Tanaka M Zhao Y a další

Zdroj: Peptides [Peptides] 2024 Jan; Vol. 171, pp. 171118. Date of Electronic Publication: 2023 Nov 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

Výrazy ze slovníku MeSH: Adrenomedullin*/genetics , Adrenomedullin*/metabolism , Respiratory Distress Syndrome*/genetics, Animals ; Mice ; Inflammation ; Lipopolysaccharides ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Proteins/genetics ; Receptors, Adrenomedullin/genetics ; Receptors, Adrenomedullin/metabolism

Activation of Calcitonin Gene-Related Peptide and Adrenomedullin Receptors by PEGylated Adrenomedullin.

Autoři: Akashi E Nagata S Yamasaki M a další

Zdroj: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2020; Vol. 43 (11), pp. 1799-1803.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 9311984 Publication Model: Print Cited Medium: Internet ISSN: 1347-5215 (Electronic) Linking ISSN: 09186158 NLM ISO Abbreviation: Biol Pharm Bull Subsets: MEDLINE

Výrazy ze slovníku MeSH: Adrenomedullin/*pharmacology , Receptor Activity-Modifying Protein 1/*agonists , Receptor Activity-Modifying Protein 2/*agonists , Receptor Activity-Modifying Protein 3/*agonists, Adrenomedullin/analogs & derivatives ; HEK293 Cells ; Half-Life ; Humans ; Polyethylene Glycols/chemistry ; Receptor Activity-Modifying Protein 1/genetics ; Receptor Activity-Modifying Protein 1/metabolism ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism

RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis.

Autoři: Mackie DI Nielsen NR Harris M a další

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Nov 26; Vol. 116 (48), pp. 24093-24099. Date of Electronic Publication: 2019 Nov 11.

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptor Activity-Modifying Protein 3/*physiology , Receptors, CCR3/*metabolism, Bioluminescence Resonance Energy Transfer Techniques ; Cell Movement ; HEK293 Cells ; Humans ; Lysosomes/metabolism ; Neovascularization, Physiologic ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Receptors, CXCR/metabolism ; Signal Transduction

Expression profile of adrenomedullin and its specific receptors in liver tissues from patients with hepatocellular carcinoma and in tumorigenic cell line-secreted extracellular vesicles.

Autoři: Cabiati M Gaggini M De Simone P a další

Zdroj: Pathology, research and practice [Pathol Res Pract] 2023 Mar; Vol. 243, pp. 154383. Date of Electronic Publication: 2023 Feb 20.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE

Výrazy ze slovníku MeSH: Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/genetics, Humans ; Adrenomedullin/genetics ; Adrenomedullin/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Calcitonin Receptor-Like Protein/genetics ; Cell Line ; Carcinogenesis

RAMP3 is a prognostic indicator of liver cancer and might reduce the adverse effect of TP53 mutation on survival.

Autoři: Fang A Zhou S Su X a další

Zdroj: Future oncology (London, England) [Future Oncol] 2018 Oct; Vol. 14 (25), pp. 2615-2625. Date of Electronic Publication: 2018 Jun 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101256629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8301 (Electronic) Linking ISSN: 14796694 NLM ISO Abbreviation: Future Oncol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mutation*, Carcinoma, Hepatocellular/*mortality , Liver Neoplasms/*mortality , Receptor Activity-Modifying Protein 3/*physiology , Tumor Suppressor Protein p53/*genetics, Adult ; Aged ; Carcinoma, Hepatocellular/chemistry ; Carcinoma, Hepatocellular/genetics ; DNA Methylation ; Female ; Humans ; Liver/chemistry ; Liver Neoplasms/chemistry ; Liver Neoplasms/genetics ; Male ; Middle Aged ; Prognosis ; Receptor Activity-Modifying Protein 3/analysis ; Receptor Activity-Modifying Protein 3/genetics

Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.

Autoři: Kotliar IB Ceraudo E Kemelmakher-Liben K a další

Zdroj: The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104664. Date of Electronic Publication: 2023 Mar 30.

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptor Activity-Modifying Proteins*/chemistry , Receptor Activity-Modifying Proteins*/metabolism , Receptors, G-Protein-Coupled*/chemistry , Receptors, G-Protein-Coupled*/metabolism , Pruritus*/metabolism, Cell Membrane/metabolism ; Receptor Activity-Modifying Protein 1/metabolism ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 3/metabolism ; Signal Transduction ; Protein Binding ; Humans

RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders.

Autoři: Liu T Kamiyoshi A Tanaka M a další

Zdroj: Peptides [Peptides] 2018 Dec; Vol. 110, pp. 10-18. Date of Electronic Publication: 2018 Oct 29.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides

Výrazy ze slovníku MeSH: Obesity/*metabolism , Postmenopause/*metabolism , Receptor Activity-Modifying Protein 3/*metabolism, Adipose Tissue/metabolism ; Animals ; Body Weight ; Diet, High-Fat/adverse effects ; Female ; Glucose Tolerance Test ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Ovariectomy ; Rats ; Real-Time Polymerase Chain Reaction ; Receptor Activity-Modifying Protein 3/deficiency

Is the activity of CGRP and Adrenomedullin regulated by RAMP (-2) and (-3) in Trypanosomatidae? An in-silico approach.

Autoři: Febres A Vanegas O Giammarresi M a další

Zdroj: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2018 Jul; Vol. 61, pp. 197-206. Date of Electronic Publication: 2018 Apr 05.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 101084138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1567-7257 (Electronic) Linking ISSN: 15671348 NLM ISO Abbreviation: Infect Genet Evol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Leishmania*/chemistry , Leishmania*/metabolism , Leishmania*/physiology, Adrenomedullin/*metabolism , Calcitonin Gene-Related Peptide/*metabolism , Receptor Activity-Modifying Protein 2/*metabolism , Receptor Activity-Modifying Protein 3/*metabolism, Amino Acid Sequence ; Chemotaxis/physiology ; Computer Simulation ; Humans ; Life Cycle Stages/physiology ; Protozoan Proteins/chemistry ; Protozoan Proteins/metabolism ; Receptor Activity-Modifying Protein 2/chemistry ; Receptor Activity-Modifying Protein 3/chemistry ; Sequence Alignment ; Sequence Homology, Amino Acid

Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells.

Autoři: Willi M Yoo KH Reinisch F a další

Zdroj: Nature communications [Nat Commun] 2017 Jul 17; Vol. 8, pp. 16069. Date of Electronic Publication: 2017 Jul 17.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy ze slovníku MeSH: CCCTC-Binding Factor/*genetics , Chromatin/*metabolism , Gene Expression Regulation/*genetics , Mammary Glands, Animal/*metabolism , Milk Proteins/*genetics , Receptor Activity-Modifying Protein 3/*genetics , Regulatory Elements, Transcriptional/*genetics, Animals ; Binding Sites ; CCCTC-Binding Factor/metabolism ; DNA Mutational Analysis ; Enhancer Elements, Genetic/genetics ; Female ; Gene Regulatory Networks ; Mice ; Milk Proteins/metabolism ; Promoter Regions, Genetic ; Receptor Activity-Modifying Protein 3/metabolism

Plasma Clearance of Intravenously Infused Adrenomedullin in Rats with Acute Renal Failure.

Autoři: Hosoda H Nakamura T Yoshihara F

Zdroj: Biomolecules [Biomolecules] 2022 Sep 11; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 11.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Výrazy ze slovníku MeSH: Acute Kidney Injury*/metabolism , Adrenomedullin*/pharmacokinetics, Animals ; Calcitonin Receptor-Like Protein/metabolism ; Chlorides ; Humans ; Mercury ; Mice ; Rats ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 3/metabolism ; Receptors, Adrenomedullin/metabolism

Targeting the adrenomedullin-2 receptor for the discovery and development of novel anti-cancer agents.

Autoři: Jailani ABA Bigos KJA Avgoustou P a další

Zdroj: Expert opinion on drug discovery [Expert Opin Drug Discov] 2022 Aug; Vol. 17 (8), pp. 839-848. Date of Electronic Publication: 2022 Jun 22.

Způsob vydávání: Journal Article; Review; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101295755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1746-045X (Electronic) Linking ISSN: 17460441 NLM ISO Abbreviation: Expert Opin Drug Discov Subsets: MEDLINE

Výrazy ze slovníku MeSH: Antineoplastic Agents*/pharmacology , Neoplasms*/drug therapy, Adrenomedullin ; Calcitonin Receptor-Like Protein/chemistry ; Humans ; Receptor Activity-Modifying Protein 2/chemistry ; Receptor Activity-Modifying Protein 3/chemistry ; Receptors, Adrenomedullin/chemistry ; Tumor Microenvironment

Accelerated Development With Increased Bone Mass and Skeletal Response to Loading Suggest Receptor Activity Modifying Protein-3 as a Bone Anabolic Target.

Autoři: Pacharne S Livesey M Kadmiel M a další

Zdroj: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Jan 12; Vol. 12, pp. 807882. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2021).

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

Výrazy ze slovníku MeSH: Intracellular Signaling Peptides and Proteins* , Membrane Proteins*/genetics, Animals ; Mice ; Mice, Knockout ; Receptor Activity-Modifying Protein 1 ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Proteins/metabolism

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.

Autoři: Watkins HA Chakravarthy M Abhayawardana RS a další

Zdroj: The Journal of biological chemistry [J Biol Chem] 2016 May 27; Vol. 291 (22), pp. 11657-75. Date of Electronic Publication: 2016 Mar 24.

Způsob vydávání: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Adrenomedullin/*metabolism , Calcitonin Receptor-Like Protein/*metabolism , Receptor Activity-Modifying Protein 2/*metabolism , Receptor Activity-Modifying Protein 3/*metabolism, Adrenomedullin/genetics ; Amino Acid Sequence ; Calcitonin Receptor-Like Protein/chemistry ; Calcitonin Receptor-Like Protein/genetics ; Crystallography, X-Ray ; Humans ; Models, Molecular ; Protein Binding ; Receptor Activity-Modifying Protein 2/chemistry ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 3/chemistry ; Receptor Activity-Modifying Protein 3/genetics ; Receptors, Adrenomedullin/chemistry ; Receptors, Adrenomedullin/genetics ; Receptors, Adrenomedullin/metabolism ; Sequence Alignment

Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress.

Autoři: Cui N Sakurai T Kamiyoshi A a další

Zdroj: Endocrinology [Endocrinology] 2021 Mar 01; Vol. 162 (3).

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Výrazy ze slovníku MeSH: Adrenomedullin/*physiology , Cardiovascular System/*physiopathology , Receptor Activity-Modifying Proteins/*physiology , Stress, Physiological/*physiology, Adrenomedullin/metabolism ; Animals ; Animals, Newborn ; Cardiomegaly/genetics ; Cardiomegaly/metabolism ; Cardiomegaly/pathology ; Cardiomegaly/physiopathology ; Cardiovascular System/metabolism ; Cardiovascular System/pathology ; Cells, Cultured ; Constriction, Pathologic ; Coronary Stenosis/genetics ; Coronary Stenosis/metabolism ; Coronary Stenosis/pathology ; Coronary Stenosis/physiopathology ; Hemodynamics/genetics ; Homeostasis/genetics ; Mice ; Mice, Knockout ; Myocytes, Cardiac/pathology ; Myocytes, Cardiac/physiology ; Oxidative Stress/genetics ; Receptor Activity-Modifying Protein 2/genetics ; Receptor Activity-Modifying Protein 2/metabolism ; Receptor Activity-Modifying Protein 2/physiology ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Receptor Activity-Modifying Protein 3/physiology ; Receptor Activity-Modifying Proteins/genetics ; Receptor Activity-Modifying Proteins/metabolism ; Signal Transduction/genetics ; Signal Transduction/physiology

Amylin receptor insensitivity impairs hypothalamic POMC neuron differentiation in the male offspring of maternal high-fat diet-fed mice.

Autoři: Li C Xu JJ Hu HT a další

Zdroj: Molecular metabolism [Mol Metab] 2021 Feb; Vol. 44, pp. 101135. Date of Electronic Publication: 2020 Dec 03.

Způsob vydávání: Journal Article; Research Support, Non-U.S. Gov't

Informace o časopise: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

Výrazy ze slovníku MeSH: Cell Differentiation*, Diet, High-Fat/*adverse effects , Hypothalamus/*metabolism , Neurons/*metabolism , Pro-Opiomelanocortin/*metabolism , Receptors, Islet Amyloid Polypeptide/*metabolism, Agouti-Related Protein/metabolism ; Animals ; Arcuate Nucleus of Hypothalamus/metabolism ; Body Weight ; Female ; HEK293 Cells ; Humans ; Islet Amyloid Polypeptide/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neurogenesis ; Neuropeptide Y/metabolism ; Pregnancy ; RNA-Binding Proteins/metabolism ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Stem Cells ; alpha-MSH/metabolism

Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury.

Autoři: Cui SY Zhang W Cui ZM a další

Zdroj: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jan 06; Vol. 16 (1), pp. 6. Date of Electronic Publication: 2021 Jan 06.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Gene Knockdown Techniques*, Apoptosis/*genetics , Lymphoid Enhancer-Binding Factor 1/*genetics , Lymphoid Enhancer-Binding Factor 1/*physiology , Microglia/*pathology , RNA, Long Noncoding/*genetics , RNA, Long Noncoding/*physiology , Spinal Cord Injuries/*genetics , Spinal Cord Injuries/*pathology, Animals ; Cell Survival/genetics ; Disease Progression ; Down-Regulation ; Inflammation ; Lymphoid Enhancer-Binding Factor 1/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Rats, Sprague-Dawley ; Rats, Wistar ; Receptor Activity-Modifying Protein 3/genetics ; Receptor Activity-Modifying Protein 3/metabolism ; Up-Regulation ; Rats