Výsledky vyhľadávania - "Radiopharmaceuticals"

Comparative evaluation of three ¹⁸ F-fluorinated FAP ligands in rodent tumor models.

Autori: Hoffmann C Gröner B Bahutski V a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118103. Date of Electronic Publication: 2025 Aug 27.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fluorine Radioisotopes*/chemistry , Membrane Proteins*/metabolism , Membrane Proteins*/antagonists & inhibitors , Gelatinases*/metabolism , Gelatinases*/antagonists & inhibitors , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/pharmacokinetics , Radiopharmaceuticals*/pharmacology , Serine Endopeptidases*/metabolism, Animals ; Humans ; Mice ; Ligands ; Rats ; Cell Line, Tumor ; Positron-Emission Tomography ; Molecular Structure ; Tissue Distribution ; Endopeptidases ; Male

Radiopharmaceutical Safety: Making It Easy.

Autori: Shupe EM; Ella-Mae Shupe.

Zdroj: Clinical journal of oncology nursing [Clin J Oncol Nurs] 2025 Nov 19; Vol. 29 (6), pp. 462-465.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oncology Nursing Press Country of Publication: United States NLM ID: 9705336 Publication Model: Print Cited Medium: Internet ISSN: 1538-067X (Electronic) Linking ISSN: 10921095 NLM ISO Abbreviation: Clin J Oncol Nurs Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/adverse effects , Radiopharmaceuticals*/therapeutic use , Neoplasms*/radiotherapy , Neoplasms*/drug therapy , Patient Safety*, Humans

Recent advances in understanding and improving the stability of ²¹¹ At-radiopharmaceuticals.

Autori: Fouinneteau R Galland N Perrio C a ďalší

Zdroj: Nuclear medicine and biology [Nucl Med Biol] 2025 Nov-Dec; Vol. 150-151, pp. 109573. Date of Electronic Publication: 2025 Oct 16.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 9304420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9614 (Electronic) Linking ISSN: 09698051 NLM ISO Abbreviation: Nucl Med Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/metabolism , Astatine*/chemistry , Astatine*/therapeutic use, Drug Stability ; Humans ; Animals ; Radiochemistry ; Isotope Labeling

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation.

Autori: Li J Wen X Reszegi RR a ďalší

Zdroj: Cancer communications (London, England) [Cancer Commun (Lond)] 2025 Nov; Vol. 45 (11), pp. 1431-1455. Date of Electronic Publication: 2025 Sep 20.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101723675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-3548 (Electronic) Linking ISSN: 25233548 NLM ISO Abbreviation: Cancer Commun (Lond) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/therapeutic use , Radiopharmaceuticals*/pharmacology , Neoplasms*/radiotherapy , Neoplasms*/metabolism , Neoplasms*/diagnostic imaging , Receptor, Cholecystokinin B*/metabolism , Receptor, Cholecystokinin B*/antagonists & inhibitors, Humans ; Animals ; Theranostic Nanomedicine/methods ; Translational Research, Biomedical ; Molecular Targeted Therapy/methods

Radiolabeling, quality control, and in vitro cell culture studies of [ ^99m Tc]Tc-tamoxifen citrate for estrogen receptor-positive breast cancer imaging.

Autori: Okşaş H Ekinci M

Zdroj: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2025 Nov; Vol. 225, pp. 112023. Date of Electronic Publication: 2025 Jul 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 9306253 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9800 (Electronic) Linking ISSN: 09698043 NLM ISO Abbreviation: Appl Radiat Isot Subsets: MEDLINE

Výrazy zo slovníka MeSH: Breast Neoplasms*/diagnostic imaging , Breast Neoplasms*/metabolism , Tamoxifen*/pharmacokinetics , Tamoxifen*/chemistry , Tamoxifen*/analogs & derivatives , Receptors, Estrogen*/metabolism , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/pharmacokinetics , Organotechnetium Compounds*/pharmacokinetics , Organotechnetium Compounds*/chemical synthesis , Organotechnetium Compounds*/chemistry , Technetium*/chemistry, Humans ; Female ; Isotope Labeling/methods ; Isotope Labeling/standards ; Quality Control ; Cell Line, Tumor ; MCF-7 Cells

Assessment of the impact of the nuclear properties of β^- -emitting radionuclides on the dosimetry of two radiopharmaceuticals with distinct pharmacokinetics.

Autori: Nardo L De Zan S Allen KJH a ďalší

Zdroj: Physics in medicine and biology [Phys Med Biol] 2025 Oct 07; Vol. 70 (20). Date of Electronic Publication: 2025 Oct 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: IOP Publishing Country of Publication: England NLM ID: 0401220 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6560 (Electronic) Linking ISSN: 00319155 NLM ISO Abbreviation: Phys Med Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/pharmacokinetics , Radiopharmaceuticals*/therapeutic use , Radioisotopes*/therapeutic use , Radioisotopes*/pharmacokinetics , Beta Particles*/therapeutic use, Radiometry ; Humans ; Female ; Mice ; Animals ; Tissue Distribution ; Male ; Phantoms, Imaging ; Antibodies, Monoclonal, Humanized/pharmacokinetics ; Antibodies, Monoclonal, Humanized/therapeutic use

Radiolabelled Cyclodextrins for the Positron Emission Tomography Imaging of Breast Cancer: Preclinical Perspectives.

Autori: Sass T Szabó JP Dienes RA a ďalší

Zdroj: Clinical and translational science [Clin Transl Sci] 2025 Oct; Vol. 18 (10), pp. e70379.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Positron-Emission Tomography*/methods , Breast Neoplasms*/diagnostic imaging , Breast Neoplasms*/pathology , Cyclodextrins*/pharmacokinetics , Cyclodextrins*/chemistry , Radiopharmaceuticals*/pharmacokinetics , Radiopharmaceuticals*/administration & dosage, Animals ; Female ; Humans ; Mice ; Gallium Radioisotopes/administration & dosage ; Gallium Radioisotopes/pharmacokinetics ; Cell Line, Tumor ; Mice, SCID ; Tissue Distribution ; Acetates ; Xenograft Model Antitumor Assays ; beta-Cyclodextrins

Exploring the chemistry of H 2 DEDPA derivatives for [ ^nat/68 Ga]Ga ³⁺ complexation.

Autori: Torralba-Maldonado D Marlin A Tran PN a ďalší

Zdroj: Journal of inorganic biochemistry [J Inorg Biochem] 2025 Oct; Vol. 271, pp. 112946. Date of Electronic Publication: 2025 May 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Gallium Radioisotopes*/chemistry , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Coordination Complexes*/pharmacokinetics , Picolinic Acids*/chemistry , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/pharmacokinetics, Crystallography, X-Ray ; Chelating Agents/chemistry

A concise review on MDM2 inhibitors and recent progress in radiopharmaceutical development for imaging MDM2 expression in tumors with PET or SPECT.

Autori: Siriki A Ragland G Vasireddy J a ďalší

Zdroj: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2025 Dec 15; Vol. 129, pp. 130394. Date of Electronic Publication: 2025 Sep 04.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proto-Oncogene Proteins c-mdm2*/antagonists & inhibitors , Proto-Oncogene Proteins c-mdm2*/metabolism , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/pharmacology , Radiopharmaceuticals*/chemical synthesis , Neoplasms*/diagnostic imaging , Neoplasms*/metabolism , Tomography, Emission-Computed, Single-Photon* , Positron-Emission Tomography*, Humans ; Animals ; Molecular Structure

Development of novel ¹⁸ F-labelled FAP-targeting tracers with improved pharmacokinetics: From preclinical optimization to clinical translation.

Autori: Feng D Li B Yang J a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118152. Date of Electronic Publication: 2025 Sep 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fluorine Radioisotopes*/chemistry , Radiopharmaceuticals*/pharmacokinetics , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/chemical synthesis , Gelatinases*/metabolism , Membrane Proteins*/metabolism , Serine Endopeptidases*/metabolism, Humans ; Animals ; Mice ; Positron-Emission Tomography ; Molecular Structure ; Tissue Distribution ; Structure-Activity Relationship ; Endopeptidases

VyPAL2 peptide asparaginyl ligase enables versatile workflows for radiolabeling single-domain antibody-based theranostics.

Autori: Declercq S Chen WM El Sahili A a ďalší

Zdroj: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Dec 10; Vol. 388 (Pt 2), pp. 114361. Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Výrazy zo slovníka MeSH: Peptide Synthases*/chemistry , Peptide Synthases*/isolation & purification , Peptide Synthases*/metabolism , Single-Domain Antibodies*/chemistry , Radiopharmaceuticals*/chemistry , Gallium Radioisotopes*/chemistry, Precision Medicine ; Viola/chemistry ; Viola/enzymology ; Radioligand Assay ; Mice, Inbred C57BL ; Humans ; Male ; Female ; Animals ; Mice ; Mice, Nude

Iron-catalyzed three-component amino(radio)fluorination of alkenes to unprotected β-(radio)fluoroamines.

Autori: Li Y Zhou Y Bortolus MR a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Dec 05; Vol. 16 (1), pp. 10917. Date of Electronic Publication: 2025 Dec 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alkenes*/chemistry , Iron*/chemistry , Fluorine Radioisotopes*/chemistry , Amines*/chemistry , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/chemistry, Catalysis ; Halogenation ; Positron-Emission Tomography

Development of triazole-based positron emission tomography ligands targeting glutaminyl cyclases (QCs) in the brain.

Autori: Li W Zhang X Yu L a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118060. Date of Electronic Publication: 2025 Aug 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aminoacyltransferases*/metabolism , Aminoacyltransferases*/antagonists & inhibitors , Brain*/diagnostic imaging , Brain*/metabolism , Positron-Emission Tomography* , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/chemical synthesis , Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Triazoles*/metabolism, Animals ; Humans ; Male ; Mice ; Rats ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/metabolism ; Dose-Response Relationship, Drug ; Fluorine Radioisotopes ; Ligands ; Mice, Transgenic ; Molecular Structure ; Structure-Activity Relationship ; Tissue Distribution ; Pharmacokinetics

Availability of Radiopharmaceuticals and Imaging Equipment in English-Speaking African Countries.

Autori: Mosima LS Manicum AE Summers B

Zdroj: Journal of nuclear medicine technology [J Nucl Med Technol] 2025 Dec 04; Vol. 53 (Suppl 1), pp. 118S-124S. Date of Electronic Publication: 2025 Dec 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0430303 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5675 (Electronic) Linking ISSN: 00914916 NLM ISO Abbreviation: J Nucl Med Technol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/supply & distribution , Language* , Health Services Accessibility*/statistics & numerical data , Diagnostic Imaging*/instrumentation, Africa ; Humans ; Cross-Sectional Studies

Extravasation of Therapeutic Radiopharmaceuticals: A Systematic Review and Management Proposal.

Autori: Gebruers J Terwinghe C Graven LH a ďalší

Zdroj: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Dec 03; Vol. 66 (12), pp. 1948-1955. Date of Electronic Publication: 2025 Dec 03.

Spôsob vydávania: Journal Article; Systematic Review

Informácie o časopise: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/adverse effects , Radiopharmaceuticals*/therapeutic use , Extravasation of Diagnostic and Therapeutic Materials*/therapy, Humans

Radiopharmaceutical Therapy: Rapid Growth, Rising Challenges, and the Critical Need for Expertise.

Autori: Jacene HA Urbain JL Lewis JS a ďalší

Zdroj: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Dec 03; Vol. 66 (12), pp. 1871-1879. Date of Electronic Publication: 2025 Dec 03.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Radiopharmaceuticals*/therapeutic use , Nuclear Medicine*/education, Humans

Advances in Radioembolization for Liver Cancer.

Autori: Meiselman S Thomas MA Giardina JD a ďalší

Zdroj: Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2025 Dec; Vol. 36 (12), pp. 1876-1881.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Society of Cardiovascular and Interventional Radiology Country of Publication: United States NLM ID: 9203369 Publication Model: Print Cited Medium: Internet ISSN: 1535-7732 (Electronic) Linking ISSN: 10510443 NLM ISO Abbreviation: J Vasc Interv Radiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Liver Neoplasms*/radiotherapy , Liver Neoplasms*/diagnostic imaging , Liver Neoplasms*/pathology , Radiopharmaceuticals*/administration & dosage , Radiopharmaceuticals*/adverse effects , Embolization, Therapeutic*/methods , Embolization, Therapeutic*/adverse effects , Embolization, Therapeutic*/trends , Yttrium Radioisotopes*/administration & dosage , Yttrium Radioisotopes*/adverse effects, Humans ; Animals ; Treatment Outcome ; Microspheres

Recent advances in radionuclide drug conjugates (RDCs) for cancer theranostics: From targeted design to clinical translation.

Autori: Xijing L Cheng B

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109240. Date of Electronic Publication: 2025 Nov 13.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/drug therapy , Neoplasms*/diagnosis , Radioisotopes*/chemistry , Radioisotopes*/therapeutic use , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/pharmacology , Drug Design* , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/therapeutic use , Theranostic Nanomedicine* , Immunoconjugates*/chemistry , Immunoconjugates*/therapeutic use, Humans ; Animals ; Molecular Structure

Development and Evaluation of Peptide-Based [ ¹⁸ F]AlF-WT12 and [ ¹⁸ F]AlF-IPB-WT12 Radiotracers for Noninvasive PD-L1 Imaging in Tumor Models.

Autori: Mo C Tan JE Zhang M a ďalší

Zdroj: Molecular pharmaceutics [Mol Pharm] 2025 Dec 01; Vol. 22 (12), pp. 7500-7512. Date of Electronic Publication: 2025 Nov 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: B7-H1 Antigen*/metabolism , Fluorine Radioisotopes*/chemistry , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/pharmacokinetics , Peptides*/chemistry , Neoplasms*/diagnostic imaging, Animals ; Mice ; Humans ; Positron-Emission Tomography/methods ; Tissue Distribution ; Cell Line, Tumor ; Female ; Mice, Inbred BALB C ; Cricetulus ; A549 Cells ; CHO Cells

Automated production of radiotracer [ ¹⁸ F]FZTA for imaging sphingosine-1-phosphate receptor 1 (S1PR1) in human.

Autori: Qiu L Bognar C Tangadanchu VKR a ďalší

Zdroj: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2025 Dec; Vol. 226, pp. 112136. Date of Electronic Publication: 2025 Aug 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 9306253 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9800 (Electronic) Linking ISSN: 09698043 NLM ISO Abbreviation: Appl Radiat Isot Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fluorine Radioisotopes*/chemistry , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/chemistry , Sphingosine-1-Phosphate Receptors*/metabolism , Oxadiazoles*/chemical synthesis , Oxadiazoles*/chemistry, Humans ; Positron-Emission Tomography/methods ; Automation