Suchergebnisse - "RNA-binding proteins"

RNA-protein interaction techniques - A historical and comparative analysis.

Autoren: Chakrabarty S Roy S Sarkar S et al.

Quelle: Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2025 Dec; Vol. 1868 (4), pp. 195115. Date of Electronic Publication: 2025 Sep 11.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-4320 (Electronic) Linking ISSN: 18749399 NLM ISO Abbreviation: Biochim Biophys Acta Gene Regul Mech Subsets: MEDLINE

MeSH-Schlagworte: RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , RNA*/metabolism , RNA*/genetics, Humans ; Protein Binding ; Animals

Key RNA-binding proteins in renal fibrosis: a comprehensive bioinformatics and machine learning framework for diagnostic and therapeutic insights.

Autoren: Chen J Zhang B Huang Q et al.

Quelle: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2463560. Date of Electronic Publication: 2025 Feb 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH-Schlagworte: Machine Learning* , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Kidney*/pathology , Kidney*/metabolism , Renal Insufficiency, Chronic*/pathology , Renal Insufficiency, Chronic*/genetics, Fibrosis ; Animals ; Computational Biology/methods ; Mice ; Humans ; Disease Models, Animal ; Ureteral Obstruction/complications ; Biomarkers/metabolism ; Single-Cell Analysis

ELAV/Hu RNA-binding protein family: key regulators in neurological disorders, cancer, and other diseases.

Autoren: Wutikeli H Xie T Xiong W et al.

Quelle: RNA biology [RNA Biol] 2025 Dec; Vol. 22 (1), pp. 1-11. Date of Electronic Publication: 2025 Mar 20.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

MeSH-Schlagworte: Nervous System Diseases*/metabolism , Nervous System Diseases*/genetics , Neoplasms*/metabolism , Neoplasms*/genetics , ELAV Proteins*/metabolism , ELAV Proteins*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Humans ; Animals ; Gene Expression Regulation

The role of RNA binding proteins in regulating oocyte maturation.

Autoren: Chen L Chen J

Quelle: Cellular signalling [Cell Signal] 2025 Dec; Vol. 136, pp. 112150. Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

MeSH-Schlagworte: RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Oocytes*/metabolism , Oocytes*/cytology , Oogenesis*, Humans ; Animals ; Female ; RNA, Messenger/metabolism ; RNA, Messenger/genetics

Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is altered in striated muscle diseases.

Autoren: Gentile GM Blue RE Goda GA et al.

Quelle: RNA biology [RNA Biol] 2025 Dec; Vol. 22 (1), pp. 1-20. Date of Electronic Publication: 2025 May 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

MeSH-Schlagworte: Alternative Splicing* , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Exons* , RNA Splicing Factors*/metabolism , RNA Splicing Factors*/genetics , Qc-SNARE Proteins*/genetics , Qc-SNARE Proteins*/metabolism , Vesicular Transport Proteins*/genetics , Vesicular Transport Proteins*/metabolism , Muscular Diseases*/genetics , Muscular Diseases*/metabolism, Animals ; Mice ; Humans ; Organ Specificity ; Muscle, Skeletal/metabolism ; Muscle, Striated/metabolism ; Repressor Proteins

RNA-binding proteins as therapeutic targets in cancer.

Autoren: Jungfleisch J Gebauer F

Quelle: RNA biology [RNA Biol] 2025 Dec; Vol. 22 (1), pp. 1-8. Date of Electronic Publication: 2025 Feb 27.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

MeSH-Schlagworte: RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/antagonists & inhibitors , Neoplasms*/genetics , Neoplasms*/metabolism , Neoplasms*/drug therapy , Neoplasms*/therapy , Neoplasms*/pathology , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/pharmacology, Humans ; Molecular Targeted Therapy ; Gene Expression Regulation, Neoplastic/drug effects ; Animals

Unraveling the impact of VHL exon 2 mutations in erythrocytosis or von Hippel-Lindau disease identified RNA-binding proteins involved in VHL splicing.

Autoren: Karaghiannis V Schmitt L Chesnel F et al.

Quelle: American journal of human genetics [Am J Hum Genet] 2025 Nov 06; Vol. 112 (11), pp. 2591-2604. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

MeSH-Schlagworte: Von Hippel-Lindau Tumor Suppressor Protein*/genetics , Von Hippel-Lindau Tumor Suppressor Protein*/metabolism , Polycythemia*/genetics , von Hippel-Lindau Disease*/genetics , RNA Splicing*/genetics , Exons*/genetics , Mutation*/genetics , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism, Humans ; Protein Stability ; Mutation, Missense ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H/genetics ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H/metabolism

DRBD3 regulates long non-coding RNA abundance and cryptic splice site selection in trypanosomes.

Autoren: Ceballos-Pérez G Gómez-Liñán C Sánchez-Luque FJ et al.

Quelle: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Nov 06; Vol. 82 (1), pp. 386. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

MeSH-Schlagworte: RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Trypanosoma brucei brucei*/genetics , Trypanosoma brucei brucei*/metabolism , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Protozoan Proteins*/genetics , Protozoan Proteins*/metabolism , RNA Splice Sites*/genetics, RNA Splicing ; RNA, Protozoan/genetics ; RNA, Protozoan/metabolism ; Introns ; Alternative Splicing

A narrative review of RNA-binding proteins: Key players in cardiovascular health and disease.

Autoren: Yang S Cao N Zhang Y et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 329 (Pt 2), pp. 147826. Date of Electronic Publication: 2025 Sep 21.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Cardiovascular Diseases*/metabolism , Cardiovascular Diseases*/genetics , Cardiovascular Diseases*/pathology , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Cardiovascular System*/metabolism, Humans ; Animals ; Gene Expression Regulation

Navigation of Nanos germ cell specification factor to germ granules-posttranscriptional regulation hubs-across species†.

Autoren: Lakshmi B Alla M Jaruzelska J

Quelle: Biology of reproduction [Biol Reprod] 2025 Oct 14; Vol. 113 (4), pp. 745-764.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0207224 Publication Model: Print Cited Medium: Internet ISSN: 1529-7268 (Electronic) Linking ISSN: 00063363 NLM ISO Abbreviation: Biol Reprod Subsets: MEDLINE

MeSH-Schlagworte: RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Germ Cells*/metabolism , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics, Animals ; Humans

Loss of ADAR1 in lung cancer activates anti-tumour immunity and suppresses tumour cell growth via the RIG-I/MDA5-MAVS pathway.

Autoren: Jia W Ma L Bai M et al.

Quelle: Cancer letters [Cancer Lett] 2025 Dec 28; Vol. 635, pp. 218071. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

MeSH-Schlagworte: Adenosine Deaminase*/genetics , Adenosine Deaminase*/metabolism , Lung Neoplasms*/immunology , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Interferon-Induced Helicase, IFIH1*/metabolism , Interferon-Induced Helicase, IFIH1*/genetics , DEAD Box Protein 58*/metabolism , DEAD Box Protein 58*/genetics , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics, Humans ; Animals ; Signal Transduction ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Receptors, Immunologic ; RNA, Double-Stranded/metabolism ; RNA, Double-Stranded/genetics ; Mice, Knockout ; A549 Cells

ZNF831-YTHDF1-DNMT1/3a feedback loop regulates lung carcinogenesis and progression through WNT7B-FZD5-β-catenin signalling axis.

Autoren: Chen D Chen H Zeng Y et al.

Quelle: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 338-352. Date of Electronic Publication: 2025 Sep 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH-Schlagworte: Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , DNA (Cytosine-5-)-Methyltransferase 1*/genetics , DNA (Cytosine-5-)-Methyltransferase 1*/metabolism , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Frizzled Receptors*/genetics , Frizzled Receptors*/metabolism , Wnt Proteins*/genetics , Wnt Proteins*/metabolism, Humans ; Animals ; beta Catenin/genetics ; beta Catenin/metabolism ; Mice ; DNA Methyltransferase 3A ; Gene Expression Regulation, Neoplastic ; DNA Methylation ; DNA (Cytosine-5-)-Methyltransferases/genetics ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Carcinogenesis/genetics ; Wnt Signaling Pathway ; Female ; Disease Progression ; Male ; Cell Movement ; Feedback, Physiological ; Mice, Nude ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism

Identification and validation of key covalent inhibitors targeting lung cancer proteins through integrated In Silico analysis.

Autoren: Fatima I Safhi AY Alsalhi A et al.

Quelle: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Dec 15; Vol. 792, pp. 152973. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH-Schlagworte: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , DNA-Binding Proteins*/antagonists & inhibitors , DNA-Binding Proteins*/chemistry , Lipocalin-2*/antagonists & inhibitors , Lipocalin-2*/chemistry , Lung Neoplasms*/metabolism , RNA-Binding Proteins*/antagonists & inhibitors , RNA-Binding Proteins*/chemistry , Transcription Factor DP1*/antagonists & inhibitors , Transcription Factor DP1*/chemistry, Humans ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation/drug effects ; Structure-Activity Relationship ; Ligands ; Hydrogen Bonding

RNA Binding by the Yeast Slf1 and Sro9 La-motif Domains.

Autoren: Pacheco E Shoara AA Donaldson LW

Quelle: Journal of molecular biology [J Mol Biol] 2025 Dec 15; Vol. 437 (24), pp. 169534. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/chemistry , RNA-Binding Proteins*/genetics, Molecular Dynamics Simulation ; Protein Binding ; Protein Domains ; Magnetic Resonance Spectroscopy

Deficiency of the innate immune protein IFITM3 impairs phagocytosis and promotes autism-like behaviors in mice.

Autoren: Lin G Xinying G Jingwen Q et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115599. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Membrane Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/deficiency , Microglia*/immunology , Microglia*/physiology , Phagocytosis*/immunology , Neurons*/immunology , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Autism Spectrum Disorder*/immunology , Autism Spectrum Disorder*/genetics, Animals ; Mice ; Immunity, Innate ; Mice, Inbred C57BL ; Mice, Knockout ; Male ; Apoptosis ; Humans ; Disease Models, Animal ; Behavior, Animal ; Cell Proliferation ; Signal Transduction ; Dexamethasone/pharmacology

PDCD4: A critical regulator in leukemic signaling networks and its therapeutic potential.

Autoren: Huang J Yin M Zhang R et al.

Quelle: Molecular biology reports [Mol Biol Rep] 2025 Dec 06; Vol. 53 (1), pp. 167. Date of Electronic Publication: 2025 Dec 06.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH-Schlagworte: Apoptosis Regulatory Proteins*/metabolism , Apoptosis Regulatory Proteins*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Signal Transduction* , Leukemia*/metabolism , Leukemia*/genetics , Leukemia*/pathology, Humans ; Apoptosis/genetics ; Cell Proliferation ; Animals ; Gene Expression Regulation, Leukemic

Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal cancer.

Autoren: Rokavec M Du Y Hermeking H

Quelle: Molecular biomedicine [Mol Biomed] 2025 Dec 03; Vol. 6 (1), pp. 133. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Epithelial-Mesenchymal Transition*/genetics , DNA Methylation*/genetics , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Down-Regulation* , CpG Islands*/genetics , Hepatocyte Nuclear Factor 3-alpha*/metabolism , Hepatocyte Nuclear Factor 3-alpha*/genetics , Gene Silencing*, Humans ; Animals ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Mice ; Neoplasm Metastasis ; Promoter Regions, Genetic ; Prognosis ; Cell Movement/genetics ; Female ; Male

Cold-inducible RNA-binding protein promotes gut barrier dysfunction and visceral hypersensitivity via activating mast cells in IBS-D.

Autoren: Wang T Yang P Dong S et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Dec 03; Vol. 166, pp. 115640. Date of Electronic Publication: 2025 Oct 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Mast Cells*/immunology , Mast Cells*/metabolism , Irritable Bowel Syndrome*/immunology , Irritable Bowel Syndrome*/metabolism , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Diarrhea*/immunology , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/immunology, Animals ; Mice, Knockout ; Mice ; Humans ; Male ; Mice, Inbred C57BL ; Disease Models, Animal ; TRPV Cation Channels/metabolism ; Toll-Like Receptor 4/metabolism

Probing direct interactions between nuclear proteins in cells with nxReLo.

Autoren: Ismail S Kubíková J Maichel M et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 02; Vol. 122 (48), pp. e2518711122. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Drosophila Proteins*/chemistry , Nuclear Proteins*/metabolism , Nuclear Proteins*/genetics , Nuclear Proteins*/chemistry , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Animals ; Drosophila melanogaster/metabolism ; Drosophila melanogaster/genetics ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/genetics ; Protein Binding ; Argonaute Proteins/metabolism

YTHDC2 promotes sepsis-induced cardiomyopathy by activating apoptosis and NF-κB pathway.

Autoren: Wang W Zhang TN Wang ZM et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2597565. Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Apoptosis* , Cardiomyopathies*/etiology , Cardiomyopathies*/metabolism , Cardiomyopathies*/genetics , Sepsis*/complications , Signal Transduction* , NF-kappa B*/metabolism , NF-kappa B*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Animals ; Rats ; Myocytes, Cardiac/metabolism ; Lipopolysaccharides ; Rats, Sprague-Dawley ; Male ; Cell Line ; Adenosine/analogs & derivatives