Suchergebnisse - "RNA-Seq"

Commentary: a review of technical considerations for planning an RNA-Sequencing experiment.

Autoren: Verma R Savaria-Butler A Enguita FJ et al.

Quelle: BMC genomics [BMC Genomics] 2025 Oct 14; Vol. 26 (1), pp. 918. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

MeSH-Schlagworte: Sequence Analysis, RNA*/methods , Sequence Analysis, RNA*/economics , RNA-Seq*/methods , RNA-Seq*/economics, Humans ; Gene Library ; RNA/genetics

Integrating Multiple Clustering Techniques and Performance Measures via Ranking for scRNA-Seq Data.

Autoren: Visser O Datta S

Quelle: Statistics in medicine [Stat Med] 2025 Dec; Vol. 44 (28-30), pp. e70331.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print Cited Medium: Internet ISSN: 1097-0258 (Electronic) Linking ISSN: 02776715 NLM ISO Abbreviation: Stat Med Subsets: MEDLINE

MeSH-Schlagworte: Single-Cell Analysis*/methods , Single-Cell Analysis*/statistics & numerical data , RNA-Seq*/methods , RNA-Seq*/statistics & numerical data, Cluster Analysis ; Humans ; Gene Expression Profiling/methods ; Single-Cell Gene Expression Analysis

The offonome reveals on and off states of gene expression near the detection limit of RNA-seq.

Autoren: Choi WY Zhao X Holt J et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 43141. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: RNA-Seq*/methods , Gene Expression Profiling*/methods , Neoplasms*/genetics , Gene Expression Regulation, Neoplastic* , Sequence Analysis, RNA*/methods, Humans ; Single-Cell Analysis ; Transcriptome

Single-cell RNA-seq of small-intestinal neuroendocrine tumors reveals the cell of origin and gene expression of early tumor development.

Autoren: Sei Y Forbes J Oguz C et al.

Quelle: Cell reports [Cell Rep] 2025 Nov 25; Vol. 44 (11), pp. 116500. Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Neuroendocrine Tumors*/genetics , Neuroendocrine Tumors*/pathology , Neuroendocrine Tumors*/metabolism , Single-Cell Analysis*/methods , Gene Expression Regulation, Neoplastic* , Intestinal Neoplasms*/genetics , Intestinal Neoplasms*/pathology , RNA-Seq* , Intestine, Small*/pathology , Intestine, Small*/metabolism , Carcinogenesis*/genetics , Carcinogenesis*/pathology, Humans ; Male ; Single-Cell Gene Expression Analysis

Rup (RNA-seq Usability Assessment Pipeline) - Quality Control for Bulk RNA-seq Experiments in Eukaryotes.

Autoren: Rupp O Roessner LH Kong D et al.

Quelle: Journal of visualized experiments : JoVE [J Vis Exp] 2025 Nov 07 (225). Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article; Video-Audio Media

Info zur Zeitschrift: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

MeSH-Schlagworte: RNA-Seq*/methods , RNA-Seq*/standards , RNA, Plant*/genetics , Sequence Analysis, RNA*/methods , Sequence Analysis, RNA*/standards , Software* , Eukaryota*/genetics, Quality Control

Immuno-laser capture microdissection of perfusion-fixed mouse brain tissue coupled to RNA-seq.

Autoren: Ge S Gan W Karlinsey K et al.

Quelle: Journal of neuroscience methods [J Neurosci Methods] 2025 Nov; Vol. 423, pp. 110548. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7905558 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-678X (Electronic) Linking ISSN: 01650270 NLM ISO Abbreviation: J Neurosci Methods Subsets: MEDLINE

MeSH-Schlagworte: Laser Capture Microdissection*/methods , Brain*/metabolism , Tissue Fixation*/methods , RNA-Seq*/methods , RNA*, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Gene Expression Profiling/methods ; Perfusion/methods ; Formaldehyde ; Immunohistochemistry/methods ; Polymers

Compositional data modeling of high-dimensional single cell RNA-seq (CoDA-hd): its advantages over commonly used normalization approaches.

Autoren: Huang J Yam SCP Leung KS et al.

Quelle: Journal of translational medicine [J Transl Med] 2025 Oct 21; Vol. 23 (1), pp. 1143. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH-Schlagworte: Single-Cell Analysis*/methods , RNA-Seq*/methods , Sequence Analysis, RNA* , Models, Statistical*, Humans ; Algorithms

A mixture of attention experts-embedded flow-based generative model to create synthetic cells in single-cell RNA-Seq datasets.

Autoren: Turgut Ögme SS Aydin N Kurt Z

Quelle: PLoS computational biology [PLoS Comput Biol] 2025 Oct 06; Vol. 21 (10), pp. e1013525. Date of Electronic Publication: 2025 Oct 06 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH-Schlagworte: Single-Cell Analysis*/methods , Single-Cell Analysis*/statistics & numerical data , RNA-Seq*/methods , RNA-Seq*/statistics & numerical data , Sequence Analysis, RNA*/methods, Humans ; Computational Biology/methods ; Algorithms ; Single-Cell Gene Expression Analysis

Unveiling the molecular mechanisms of hemorrhagic shock and acute lung injury: An integrative RNA-Seq and network analysis.

Autoren: Mishra M Agrawal S Mishra SP et al.

Quelle: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2025 Oct; Vol. 284, pp. 17-28. Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 101280339 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1810 (Electronic) Linking ISSN: 18781810 NLM ISO Abbreviation: Transl Res Subsets: MEDLINE

MeSH-Schlagworte: Shock, Hemorrhagic*/genetics , Shock, Hemorrhagic*/complications , Acute Lung Injury*/genetics , Acute Lung Injury*/etiology , Acute Lung Injury*/metabolism , RNA-Seq*, Animals ; Male ; Rats ; Rats, Sprague-Dawley ; Protein Interaction Maps/genetics ; Gene Regulatory Networks ; Lung/pathology ; Lung/metabolism ; Disease Models, Animal ; Transcriptome

Harnessing scRNA-seq and bulk RNA-seq to identify CD39+ T cell genes for rheumatoid arthritis diagnosis and therapy.

Autoren: Yun D Xu C Yu H et al.

Quelle: Journal of leukocyte biology [J Leukoc Biol] 2025 Oct 01; Vol. 117 (10).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print Cited Medium: Internet ISSN: 1938-3673 (Electronic) Linking ISSN: 07415400 NLM ISO Abbreviation: J Leukoc Biol Subsets: MEDLINE

MeSH-Schlagworte: Arthritis, Rheumatoid*/diagnosis , Arthritis, Rheumatoid*/genetics , Arthritis, Rheumatoid*/therapy , Arthritis, Rheumatoid*/immunology , Arthritis, Rheumatoid*/drug therapy , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , Apyrase*/metabolism , Apyrase*/genetics , RNA-Seq*/methods , Tetraspanin 29*/metabolism, Humans ; Single-Cell Analysis/methods ; Biomarkers ; Female ; Gene Expression Profiling ; Male ; MicroRNAs/genetics ; Middle Aged ; Single-Cell Gene Expression Analysis ; Antigens, CD

LncRAnalyzer: a robust workflow for long non-coding RNA discovery using RNA-Seq.

Autoren: Nikhil S Shaik Mohideen H Natesan Sella R

Quelle: The Plant journal : for cell and molecular biology [Plant J] 2025 Oct; Vol. 124 (1), pp. e70509.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Scientific Publishers and BIOS Scientific Publishers in association with the Society for Experimental Biology Country of Publication: England NLM ID: 9207397 Publication Model: Print Cited Medium: Internet ISSN: 1365-313X (Electronic) Linking ISSN: 09607412 NLM ISO Abbreviation: Plant J Subsets: MEDLINE

MeSH-Schlagworte: RNA, Long Noncoding*/genetics , RNA, Plant*/genetics , RNA-Seq*/methods , Software* , Sorghum*/genetics , Computational Biology*/methods, Workflow ; Molecular Sequence Annotation

The efficacy of RNA-seq-based endometrial receptivity test (rsERT) in guiding personalized embryo transfer in women with polycystic ovarian syndrome without recurrent implantation failure: a randomized controlled trial.

Autoren: Chen J Zhao J Hu Q et al.

Quelle: Journal of assisted reproduction and genetics [J Assist Reprod Genet] 2025 Oct; Vol. 42 (10), pp. 3321-3332. Date of Electronic Publication: 2025 Sep 13.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Springer Country of Publication: Netherlands NLM ID: 9206495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7330 (Electronic) Linking ISSN: 10580468 NLM ISO Abbreviation: J Assist Reprod Genet Subsets: MEDLINE

MeSH-Schlagworte: Embryo Transfer*/methods , Polycystic Ovary Syndrome*/genetics , Polycystic Ovary Syndrome*/pathology , Polycystic Ovary Syndrome*/complications , Embryo Implantation*/genetics , Endometrium*/metabolism , Endometrium*/pathology , RNA-Seq*/methods , Infertility, Female*/genetics , Infertility, Female*/therapy, Humans ; Female ; Pregnancy ; Adult ; Pregnancy Rate ; Fertilization in Vitro/methods

Isoformic: a workflow for transcript-level RNA-seq interpretation.

Autoren: Mamede I Queiroz LR Mata-Machado C et al.

Quelle: NAR genomics and bioinformatics [NAR Genom Bioinform] 2025 Dec 03; Vol. 7 (4), pp. lqaf176. Date of Electronic Publication: 2025 Dec 03 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 101756213 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-9268 (Electronic) Linking ISSN: 26319268 NLM ISO Abbreviation: NAR Genom Bioinform Subsets: MEDLINE

MeSH-Schlagworte: RNA-Seq*/methods , Transcriptome* , Gene Expression Profiling*/methods , Sequence Analysis, RNA*/methods , Software*, Animals ; Humans ; Mice ; COVID-19/genetics ; COVID-19/virology ; Workflow ; Female ; Alternative Splicing ; Pre-Eclampsia/genetics ; SARS-CoV-2/genetics ; Pregnancy

Pan-cancer gene set discovery via scRNA-seq for optimal deep learning based downstream tasks.

Autoren: Kim JH Lee S Jang J

Quelle: Scientific reports [Sci Rep] 2025 Dec 02; Vol. 15 (1), pp. 43159. Date of Electronic Publication: 2025 Dec 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Deep Learning* , Neoplasms*/genetics , Single-Cell Analysis*/methods , RNA-Seq*/methods , Sequence Analysis, RNA*/methods, Humans ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic ; Neural Networks, Computer ; Mutation ; Transcriptome ; Computational Biology/methods ; Single-Cell Gene Expression Analysis

Integrated single-cell RNA-seq and bulk RNA-seq analysis to investigate key adipogenesis genes in adipose-derived stem cells.

Autoren: Zhang T Cai Z Li H et al.

Quelle: PloS one [PLoS One] 2025 Dec 01; Vol. 20 (12), pp. e0335152. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Adipogenesis*/genetics , RNA-Seq*/methods , Single-Cell Analysis*/methods , Adipose Tissue*/cytology , Adipose Tissue*/metabolism , Stem Cells*/metabolism , Stem Cells*/cytology, Gene Regulatory Networks ; RNA, Long Noncoding/genetics ; Humans ; Cell Differentiation/genetics ; Adipocytes/metabolism ; Adipocytes/cytology ; MicroRNAs/genetics ; RNA, Messenger/genetics ; Animals ; Lipid Metabolism/genetics ; Gene Expression Regulation ; Gene Expression Profiling ; Single-Cell Gene Expression Analysis

D3Impute: Dropout-aware discrimination, distribution-aware modeling, and density-guide imputation for scRNA-seq data.

Autoren: Huang S Jiang L Yi M et al.

Quelle: PLoS computational biology [PLoS Comput Biol] 2025 Dec 01; Vol. 21 (12), pp. e1013744. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH-Schlagworte: Single-Cell Analysis*/methods , Single-Cell Analysis*/statistics & numerical data , Sequence Analysis, RNA*/methods , RNA-Seq*/methods, Humans ; Computational Biology/methods ; Algorithms ; Software ; Gene Expression Profiling/methods ; Transcriptome/genetics ; Single-Cell Gene Expression Analysis

GEPREP: A comprehensive data atlas of RNA-seq-based gene expression profiles of exercise responses.

Autoren: Sun L Luan J Wang J et al.

Quelle: Journal of sport and health science [J Sport Health Sci] 2025 Dec; Vol. 14, pp. 100992. Date of Electronic Publication: 2024 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Shanghai University of Sport Country of Publication: China NLM ID: 101606001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2961 (Electronic) Linking ISSN: 22132961 NLM ISO Abbreviation: J Sport Health Sci Subsets: MEDLINE

MeSH-Schlagworte: Exercise*/physiology , RNA-Seq* , Transcriptome* , Gene Expression Profiling* , Databases, Genetic*, Humans ; Animals ; Mice ; Sequence Analysis, RNA ; Muscle, Skeletal/metabolism

A diagnostic signatures for intervertebral disc degeneration using TNFAIP6 and COL6A2 based on single-cell RNA-seq and bulk RNA-seq analyses.

Autoren: Song HM Li ZW Huang Q et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2443568. Date of Electronic Publication: 2024 Dec 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Intervertebral Disc Degeneration*/genetics , Intervertebral Disc Degeneration*/diagnosis , Intervertebral Disc Degeneration*/metabolism , Collagen Type VI*/genetics , Collagen Type VI*/metabolism , RNA-Seq* , Single-Cell Analysis*/methods, Humans ; Biomarkers/metabolism ; Nucleus Pulposus/metabolism ; ROC Curve ; Male ; Single-Cell Gene Expression Analysis ; Cell Adhesion Molecules

Single-Cell RNA-Seq Revealed the Immune Microenvironment Reprogramming by Dexmedetomidine Treatment in Ischemic Stroke.

Autoren: Zhang W Wang X Zhang B et al.

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 16150-16167. Date of Electronic Publication: 2025 Aug 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Dexmedetomidine*/pharmacology , Dexmedetomidine*/therapeutic use , Ischemic Stroke*/drug therapy , Ischemic Stroke*/immunology , Ischemic Stroke*/genetics , Ischemic Stroke*/pathology , Single-Cell Analysis*/methods , RNA-Seq*/methods , Cellular Microenvironment*/drug effects, Animals ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Mice, Inbred C57BL ; Male ; Mice ; Apoptosis/drug effects ; Infarction, Middle Cerebral Artery/drug therapy ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Single-Cell Gene Expression Analysis

Integrating RNA-seq and scRNA-seq to explore the prognostic features and immune landscape of exosome-related genes in breast cancer metastasis.

Autoren: Huang G Yu Y Su H et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2447917. Date of Electronic Publication: 2025 Jan 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Breast Neoplasms*/genetics , Breast Neoplasms*/immunology , Breast Neoplasms*/pathology , Breast Neoplasms*/mortality , Exosomes*/genetics , Exosomes*/immunology , RNA-Seq*/methods, Humans ; Female ; Prognosis ; Single-Cell Analysis/methods ; Gene Expression Regulation, Neoplastic ; Neoplasm Metastasis/genetics ; Biomarkers, Tumor/genetics ; Single-Cell Gene Expression Analysis