Výsledky vyhľadávania - "RANK Ligand"

Corosolic acid modulates RANKL-triggered signaling to suppress osteoclastogenesis and ovariectomy-induced bone loss.

Autori: Zhao C Wu F Zhao L a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 882-898. Date of Electronic Publication: 2025 Oct 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/metabolism , RANK Ligand*/genetics , Osteogenesis*/drug effects , Osteoclasts*/drug effects , Osteoclasts*/metabolism , Osteoclasts*/pathology , Triterpenes*/pharmacology , Bone Resorption*/drug therapy , Bone Resorption*/pathology , Bone Resorption*/metabolism , Osteoporosis*/drug therapy , Osteoporosis*/pathology , Osteoporosis*/metabolism , Osteoporosis*/etiology, Animals ; Ovariectomy/adverse effects ; Mice ; Female ; Cell Differentiation/drug effects ; Signal Transduction/drug effects ; Reactive Oxygen Species/metabolism ; NF-kappa B/metabolism ; NF-kappa B/genetics ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; Humans ; Macrophages/drug effects ; Macrophages/metabolism ; Oxidative Stress/drug effects ; Mice, Inbred C57BL

The RANK-RANKL-OPG axis in dermatological malignancies: A systematic review.

Autori: Zartab H Maghsoodloo D Parsi-Moud A a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115624. Date of Electronic Publication: 2025 Oct 15.

Spôsob vydávania: Journal Article; Systematic Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoprotegerin*/metabolism , RANK Ligand*/metabolism , Receptor Activator of Nuclear Factor-kappa B*/metabolism , Skin Neoplasms*/drug therapy , Skin Neoplasms*/immunology , Skin Neoplasms*/metabolism , Skin Neoplasms*/pathology, Animals ; Humans ; Denosumab/therapeutic use ; Signal Transduction

LRRc17-RANKL pathway regulates mitophagy and contributes to atrial remodeling in diabetes.

Autori: Zhou L Liu D Bao Q a ďalší

Zdroj: Cellular signalling [Cell Signal] 2025 Dec; Vol. 136, pp. 112148. Date of Electronic Publication: 2025 Sep 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mitophagy* , RANK Ligand*/metabolism , RANK Ligand*/genetics , Atrial Remodeling* , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/pathology , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/complications, Animals ; Mice ; Male ; Myocytes, Cardiac/metabolism ; Mice, Inbred C57BL ; Signal Transduction ; Humans ; Heart Atria/metabolism ; Heart Atria/pathology

Structure-based discovery and molecular dynamics evaluation of dihydrorobinetin as a potential anti-osteoclastogenic RANKL inhibitor in rheumatoid arthritis.

Autori: S DSN Sundararajan V

Zdroj: Journal of biological physics [J Biol Phys] 2025 Nov 19; Vol. 51 (1), pp. 29. Date of Electronic Publication: 2025 Nov 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Kluwer Country of Publication: Netherlands NLM ID: 0417731 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-0689 (Electronic) Linking ISSN: 00920606 NLM ISO Abbreviation: J Biol Phys Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/antagonists & inhibitors , RANK Ligand*/chemistry , RANK Ligand*/metabolism , Molecular Dynamics Simulation* , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/metabolism , Arthritis, Rheumatoid*/pathology , Osteoclasts*/drug effects , Osteoclasts*/cytology , Drug Discovery*, Humans

The RANK/RANKL axis controls vascular dynamics in the bone marrow.

Autori: Kaneko T Yari S Kikuta J a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 11; Vol. 122 (45), pp. e2425366122. Date of Electronic Publication: 2025 Nov 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/metabolism , RANK Ligand*/genetics , Receptor Activator of Nuclear Factor-kappa B*/metabolism , Receptor Activator of Nuclear Factor-kappa B*/genetics , Bone Marrow*/blood supply , Bone Marrow*/metabolism , Capillary Permeability*/physiology, Animals ; Mice ; Osteoclasts/metabolism ; Osteoclasts/cytology ; Signal Transduction ; Vascular Cell Adhesion Molecule-1/metabolism ; Mice, Inbred C57BL ; Intercellular Adhesion Molecule-1/metabolism

Transcriptional regulation of Rankl by Txnip-Ecd in aging and diabetic related osteoporosis.

Autori: Cao X Liu K Yuan J a ďalší

Zdroj: Journal of advanced research [J Adv Res] 2025 Nov; Vol. 77, pp. 221-234. Date of Electronic Publication: 2025 Jan 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/genetics , RANK Ligand*/metabolism , Osteoporosis*/metabolism , Osteoporosis*/genetics , Osteoporosis*/etiology , Osteoporosis*/pathology , Carrier Proteins*/metabolism , Carrier Proteins*/genetics , Aging*/genetics , Aging*/metabolism , Thioredoxins*/metabolism , Thioredoxins*/genetics, Animals ; Mice ; Mice, Knockout ; Female ; Mesenchymal Stem Cells/metabolism ; Osteogenesis/genetics ; Humans ; Gene Expression Regulation ; Cell Differentiation ; Osteoclasts/metabolism ; Mice, Inbred C57BL

Anti-osteoporotic effect of sitagliptin in an osteoporosis model of ovariectomized rats: role of RUNX2 and RANKL/OPG ratio.

Autori: El-Marasy SA Abdel-Rahman RF Abd-Elsalam RM a ďalší

Zdroj: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Nov; Vol. 398 (11), pp. 15857-15871. Date of Electronic Publication: 2025 May 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Sitagliptin Phosphate*/pharmacology , Sitagliptin Phosphate*/therapeutic use , RANK Ligand*/metabolism , RANK Ligand*/genetics , Osteoprotegerin*/metabolism , Osteoprotegerin*/genetics , Core Binding Factor Alpha 1 Subunit*/metabolism , Core Binding Factor Alpha 1 Subunit*/genetics , Osteoporosis*/drug therapy , Osteoporosis*/metabolism , Osteoporosis*/pathology , Bone Density Conservation Agents*/pharmacology , Bone Density Conservation Agents*/therapeutic use, Animals ; Female ; Ovariectomy ; Bone Density/drug effects ; Disease Models, Animal ; Rats ; Femur/drug effects ; Femur/metabolism ; Femur/pathology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Sprague-Dawley

Idebenone attenuates RANKL-induced osteoclastogenesis and improves bone mass in ovariectomized mice.

Autori: Yu C Cai L Zhuang L a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Oct; Vol. 238, pp. 206-219. Date of Electronic Publication: 2025 Jun 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoclasts*/drug effects , Osteoclasts*/metabolism , Osteogenesis*/drug effects , RANK Ligand*/metabolism , RANK Ligand*/genetics , Ubiquinone*/analogs & derivatives , Ubiquinone*/pharmacology , Osteoporosis, Postmenopausal*/drug therapy , Osteoporosis, Postmenopausal*/pathology , Osteoporosis, Postmenopausal*/metabolism , Osteoporosis, Postmenopausal*/genetics, Animals ; Ovariectomy ; Female ; Mice ; Cell Differentiation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Humans ; Macrophages/drug effects ; Macrophages/metabolism ; Bone Density/drug effects ; Oxidative Stress/drug effects ; Bone Resorption/drug therapy ; MAP Kinase Signaling System/drug effects ; Cells, Cultured

The role of probiotics in modulating RANKL in osteoporosis: A systematic review of animal interventional studies and RCTs.

Autori: Hamedi-Kalajahi F Alizadeh M Kheirouri S

Zdroj: Bone [Bone] 2025 Dec; Vol. 201, pp. 117622. Date of Electronic Publication: 2025 Sep 01.

Spôsob vydávania: Journal Article; Systematic Review; Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE

Výrazy zo slovníka MeSH: Probiotics*/therapeutic use , Probiotics*/pharmacology , RANK Ligand*/metabolism , Osteoporosis*/metabolism , Osteoporosis*/drug therapy, Animals ; Humans ; Randomized Controlled Trials as Topic ; Disease Models, Animal

Cellular senescence of RANKL ⁺ osteoblasts and Th17 cells in severe periodontitis with occlusal trauma.

Autori: Wang Y Nakagawa M Luo C a ďalší

Zdroj: Journal of prosthodontic research [J Prosthodont Res] 2025 Nov 18; Vol. 69 (4), pp. 533-542. Date of Electronic Publication: 2025 Feb 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Japan Prosthodontic Society Country of Publication: Japan NLM ID: 101490359 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-4632 (Electronic) Linking ISSN: 18831958 NLM ISO Abbreviation: J Prosthodont Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cellular Senescence*/physiology , Periodontitis*/pathology , Periodontitis*/etiology , RANK Ligand*/metabolism , Th17 Cells*/physiology , Th17 Cells*/metabolism , Osteoblasts*/physiology , Osteoblasts*/metabolism , Osteoblasts*/pathology , Dental Occlusion, Traumatic*/complications, Animals ; Alveolar Bone Loss/etiology ; Male ; Rats, Sprague-Dawley ; Disease Models, Animal ; Osteoclasts ; Rats ; Osteogenesis

Denosumab for Primary Osteoporosis and Its Impact on Sarcopenia in the Chinese Population: Insights from Clinical Evidence and RANKL Pathway Mendelian Randomization.

Autori: Li S Hu S Zheng X a ďalší

Zdroj: Clinical interventions in aging [Clin Interv Aging] 2025 Nov 15; Vol. 20, pp. 2065-2077. Date of Electronic Publication: 2025 Nov 15 (Print Publication: 2025).

Spôsob vydávania: Case Reports; Clinical Trial; Journal Article

Informácie o časopise: Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101273480 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-1998 (Electronic) Linking ISSN: 11769092 NLM ISO Abbreviation: Clin Interv Aging Subsets: MEDLINE

Výrazy zo slovníka MeSH: Bone Density Conservation Agents*/therapeutic use , Denosumab*/therapeutic use , Osteoporosis*/drug therapy , Osteoporosis*/genetics , RANK Ligand*/genetics , Sarcopenia*/drug therapy , Sarcopenia*/genetics, Aged ; Female ; Humans ; Male ; Middle Aged ; Bone Density/drug effects ; China ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Muscle Strength/drug effects ; East Asian People/genetics

Prognostic value of RANK signalling in breast cancer: a systematic review and meta-analysis.

Autori: Li L Wang X Li Y a ďalší

Zdroj: BMJ open [BMJ Open] 2025 Nov 11; Vol. 15 (11), pp. e098846. Date of Electronic Publication: 2025 Nov 11.

Spôsob vydávania: Journal Article; Systematic Review; Meta-Analysis

Informácie o časopise: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

Výrazy zo slovníka MeSH: Breast Neoplasms*/mortality , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Receptor Activator of Nuclear Factor-kappa B*/metabolism , Osteoprotegerin*/metabolism , RANK Ligand*/metabolism, Humans ; Prognosis ; Female ; Signal Transduction ; Biomarkers, Tumor/metabolism

"Clinical and radiological evaluation of periodontal intrabony defects treated with DFDBA and 1% melatonin gel and its effect on RANKL and OPG in gingival crevicularfluid - a randomized controlled trial".

Autori: Kavya GL Kumar KA Penmetsa GS a ďalší

Zdroj: Clinical oral investigations [Clin Oral Investig] 2025 Nov 08; Vol. 29 (12), pp. 557. Date of Electronic Publication: 2025 Nov 08.

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoprotegerin*/metabolism , Gingival Crevicular Fluid*/chemistry , Gingival Crevicular Fluid*/metabolism , Melatonin*/administration & dosage , Melatonin*/therapeutic use , Melatonin*/pharmacology , RANK Ligand*/metabolism , Alveolar Bone Loss*/diagnostic imaging , Alveolar Bone Loss*/therapy , Alveolar Bone Loss*/surgery , Bone Transplantation*/methods, Humans ; Male ; Female ; Cone-Beam Computed Tomography ; Middle Aged ; Single-Blind Method ; Prospective Studies ; Gels ; Treatment Outcome ; Adult ; Biomarkers/metabolism ; Periodontal Index

CLCF1 Exercise-induced Myokine Protocol for Investigating RANKL/OPG Bone Protection Mechanisms in Postmenopausal Osteoporosis.

Autori: Zhao H Li H Sun Y

Zdroj: Journal of visualized experiments : JoVE [J Vis Exp] 2025 Nov 07 (225). Date of Electronic Publication: 2025 Nov 07.

Spôsob vydávania: Journal Article; Video-Audio Media

Informácie o časopise: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/metabolism , Osteoporosis, Postmenopausal*/metabolism , Cytokines*/metabolism , Cytokines*/genetics , Osteoprotegerin*/metabolism , Exercise*/physiology, Humans ; Female ; Osteoclasts/metabolism ; Osteoblasts/metabolism ; Myokines

Crosstalk between endothelial cells and osteoblasts stimulates ALP via Notch signaling and RANKL/OPG ratio independently of Notch signaling in vitro.

Autori: Wirsig K Bürger N Bernhardt A

Zdroj: Cellular & molecular biology letters [Cell Mol Biol Lett] 2025 Oct 02; Vol. 30 (1), pp. 108. Date of Electronic Publication: 2025 Oct 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoblasts*/metabolism , Osteoblasts*/cytology , Osteoblasts*/drug effects , RANK Ligand*/metabolism , Osteoprotegerin*/metabolism , Signal Transduction*/drug effects , Receptors, Notch*/metabolism , Alkaline Phosphatase*/metabolism, Humans ; Coculture Techniques ; Vascular Endothelial Growth Factor A/pharmacology ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/cytology ; Dexamethasone/pharmacology ; Cells, Cultured ; Cell Communication/drug effects

Impact of Myb deficiency on Rankl/Opg expression within the developing mouse mandible.

Autori: Varadinkova S Matalova E Frampton J a ďalší

Zdroj: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft [Ann Anat] 2026 Jan; Vol. 263, pp. 152753. Date of Electronic Publication: 2025 Nov 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: G. Fischer Country of Publication: Germany NLM ID: 100963897 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0402 (Electronic) Linking ISSN: 09409602 NLM ISO Abbreviation: Ann Anat Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/genetics , RANK Ligand*/metabolism , Mandible*/embryology , Mandible*/metabolism , Mandible*/growth & development , Osteoprotegerin*/genetics , Osteoprotegerin*/metabolism , Proto-Oncogene Proteins c-myb*/genetics , Proto-Oncogene Proteins c-myb*/deficiency, Animals ; Mice ; Mice, Knockout ; Gene Expression Regulation, Developmental ; Mice, Inbred C57BL

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways.

Autori: Wang YH Wu YY Tsai CH a ďalší

Zdroj: Molecular medicine reports [Mol Med Rep] 2026 Jan; Vol. 33 (1). Date of Electronic Publication: 2025 Nov 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: RANK Ligand*/metabolism , RANK Ligand*/pharmacology , Osteogenesis*/drug effects , Apelin*/pharmacology , Apelin*/metabolism , NF-kappa B*/metabolism , Osteoclasts*/metabolism , Osteoclasts*/cytology , Osteoclasts*/drug effects , MAP Kinase Signaling System*/drug effects, Animals ; Mice ; Cell Differentiation/drug effects ; Signal Transduction/drug effects ; RAW 264.7 Cells

Effects of orthodontic tooth movement on periodontal tissues after ligature-induced periodontitis through the mechanism of RANKL-induced osteoclastogenesis: an animal study.

Autori: Feyizoglu BB Aysesek BH Kaya S a ďalší

Zdroj: BMC oral health [BMC Oral Health] 2025 Jul 30; Vol. 25 (1), pp. 1278. Date of Electronic Publication: 2025 Jul 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tooth Movement Techniques*/methods , RANK Ligand*/physiology , RANK Ligand*/analysis , Periodontitis*/pathology , Periodontitis*/metabolism , Periodontitis*/therapy , Osteoclasts*/physiology , Osteogenesis*/physiology, Animals ; Rats, Wistar ; Rats ; Osteoprotegerin/analysis ; Osteoprotegerin/metabolism ; Periodontal Ligament/pathology ; Male ; Ligation ; Disease Models, Animal ; Molar

Osteocytes Produces RANKL Via Wnt-TGFβ Signaling Axis for Osteoclastogenesis.

Autori: Liu Y Zhao L Li M a ďalší

Zdroj: International journal of biological sciences [Int J Biol Sci] 2025 Sep 12; Vol. 21 (13), pp. 5821-5841. Date of Electronic Publication: 2025 Sep 12 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteocytes*/metabolism , RANK Ligand*/metabolism , RANK Ligand*/genetics , Wnt Signaling Pathway*/physiology , Wnt Signaling Pathway*/genetics , Transforming Growth Factor beta*/metabolism , Osteogenesis*/physiology , Osteogenesis*/genetics, Animals ; Mice ; Osteoclasts/metabolism ; Cell Differentiation/physiology ; Cell Differentiation/genetics ; Mice, Inbred C57BL ; Signal Transduction ; Bone Resorption/metabolism

Effects of anti-RANKL and anti-PD-1 antibodies on cancer-induced osteolysis in mice.

Autori: Chao PC Karakawa A Hosonuma M a ďalší

Zdroj: Journal of oral biosciences [J Oral Biosci] 2025 Sep; Vol. 67 (3), pp. 100682. Date of Electronic Publication: 2025 Jul 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101226721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3865 (Electronic) Linking ISSN: 13490079 NLM ISO Abbreviation: J Oral Biosci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteolysis*/drug therapy , Osteolysis*/etiology , Osteolysis*/pathology , RANK Ligand*/immunology , RANK Ligand*/antagonists & inhibitors , Programmed Cell Death 1 Receptor*/immunology , Programmed Cell Death 1 Receptor*/antagonists & inhibitors , Denosumab*/pharmacology , Denosumab*/therapeutic use , Nivolumab*/pharmacology , Antibodies, Monoclonal*/pharmacology , Immune Checkpoint Inhibitors*/pharmacology, Animals ; Mice ; Female ; Cell Line, Tumor ; Mice, Inbred BALB C ; Osteoclasts/drug effects