Suchergebnisse - "RADIATION-sensitizing agents"

Tumor microenvironment-responsive metal-natural polyphenol nanozyme for radiosensitization by interfering glucose metabolism and redox homeostasis.

Autoren: Ren J Wen Q Du S et al.

Quelle: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Dec 10; Vol. 388 (Pt 2), pp. 114219. Date of Electronic Publication: 2025 Sep 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

MeSH-Schlagworte: Glucose*/metabolism , Radiation-Sensitizing Agents*/administration & dosage , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/therapeutic use , Phloretin*/administration & dosage , Phloretin*/chemistry , Phloretin*/pharmacology , Phloretin*/therapeutic use , Neoplasms*/metabolism , Neoplasms*/radiotherapy , Polyphenols*/administration & dosage , Polyphenols*/chemistry, Tumor Microenvironment/drug effects ; Animals ; Humans ; Cell Line, Tumor ; Oxidation-Reduction ; Mice, Nude ; Mice, Inbred BALB C ; Homeostasis/drug effects ; Mice ; Reactive Oxygen Species/metabolism ; Glucose Oxidase

8-(4-Trifluoromethylthio)benzylamino-2'-deoxyadenosine: a purine nucleoside as a potential radiosensitizer.

Autoren: Datta M Szczyrba A Nowak P et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118094. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/chemical synthesis , Deoxyadenosines*/pharmacology , Deoxyadenosines*/chemistry , Deoxyadenosines*/chemical synthesis , Purine Nucleosides*/pharmacology , Purine Nucleosides*/chemistry , Purine Nucleosides*/chemical synthesis, Humans ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Cell Proliferation/drug effects ; MCF-7 Cells

A Modular Supramolecular Peptide Platform Reveals Atomic-Number-Dependent Mechanisms Driving Radioenhancement.

Autoren: Jung S Navarro PL Barbé E et al.

Quelle: ACS nano [ACS Nano] 2025 Dec 02; Vol. 19 (47), pp. 40394-40403. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

MeSH-Schlagworte: Peptides*/chemistry , Peptides*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology , Breast Neoplasms*/pathology , Contrast Media*/chemistry , Contrast Media*/pharmacology, Humans ; Gadolinium/chemistry ; Gadolinium/pharmacology ; Bismuth/chemistry ; Bismuth/pharmacology ; Animals ; Mice ; Cell Line, Tumor ; Female

Ferulic acid-loaded chitosan nanoparticles enhance radiotherapy efficacy via STAT3 suppression and caspase-8/p53 activation in Ehrlich ascites carcinoma.

Autoren: Mansour MT Hussein MA Emara AA et al.

Quelle: Scientific reports [Sci Rep] 2025 Dec 01; Vol. 15 (1), pp. 42910. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Carcinoma, Ehrlich Tumor*/radiotherapy , Carcinoma, Ehrlich Tumor*/metabolism , Carcinoma, Ehrlich Tumor*/pathology , Carcinoma, Ehrlich Tumor*/drug therapy , Chitosan*/chemistry , Coumaric Acids*/chemistry , Coumaric Acids*/pharmacology , Coumaric Acids*/administration & dosage , Caspase 8*/metabolism , Nanoparticles*/chemistry , Tumor Suppressor Protein p53*/metabolism , STAT3 Transcription Factor*/metabolism , STAT3 Transcription Factor*/antagonists & inhibitors , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry, Animals ; Mice

D-mannose augments targeted radioligand-immunotherapy of prostate cancer by enhancing radiosensitivity and reshaping immune microenvironment.

Autoren: Tao L Xu B Sun J et al.

Quelle: Drug delivery and translational research [Drug Deliv Transl Res] 2025 Dec; Vol. 15 (12), pp. 4761-4774. Date of Electronic Publication: 2025 Jun 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE

MeSH-Schlagworte: Mannose*/pharmacology , Mannose*/administration & dosage , Radiation Tolerance*/drug effects , Prostatic Neoplasms*/immunology , Prostatic Neoplasms*/therapy , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/radiotherapy , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/administration & dosage , Prostatic Neoplasms, Castration-Resistant*/immunology, Male ; Animals ; Humans ; Cell Line, Tumor ; Mice ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology ; Immunotherapy/methods ; Apoptosis/drug effects ; DNA Damage/drug effects ; Cell Proliferation/drug effects

Multifunctional HfSe 2 @TA/Fe ³⁺ nanosheets for cancer therapy: Synergistic radiosensitization, photothermal ablation, and selenium-mediated radioprotection.

Autoren: Liu B Hong C Xu J et al.

Quelle: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Dec; Vol. 699 (Pt 1), pp. 138166. Date of Electronic Publication: 2025 Jun 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

MeSH-Schlagworte: Selenium*/chemistry , Selenium*/pharmacology , Photothermal Therapy* , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology , Radiation-Protective Agents*/pharmacology , Radiation-Protective Agents*/chemistry , Nanostructures*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry, Animals ; Mice ; Mice, Inbred BALB C ; Female ; Humans ; Particle Size ; Tannins/chemistry ; Tannins/pharmacology ; Apoptosis/drug effects ; Surface Properties ; Cell Line, Tumor ; Tumor Microenvironment/drug effects ; Cell Survival/drug effects

Exploratory Rat Toxicology and Efficacy of the Boron Neutron Capture Therapy Drug Boronotyrosine in a Mouse Model of Head and Neck Cancer.

Autoren: Raitano A Kilby W Morrison K et al.

Quelle: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Dec 01; Vol. 123 (5), pp. 1395-1400. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE

MeSH-Schlagworte: Boron Neutron Capture Therapy*/methods , Boron Neutron Capture Therapy*/adverse effects , Head and Neck Neoplasms*/radiotherapy , Head and Neck Neoplasms*/pathology , Head and Neck Neoplasms*/blood , Boron Compounds*/toxicity , Boron Compounds*/administration & dosage , Boron Compounds*/pharmacokinetics , Tyrosine*/analogs & derivatives , Tyrosine*/toxicity , Tyrosine*/administration & dosage , Tyrosine*/pharmacokinetics , Radiation-Sensitizing Agents*/toxicity , Radiation-Sensitizing Agents*/administration & dosage , Radiation-Sensitizing Agents*/pharmacokinetics, Animals ; Mice ; Rats ; Mice, Nude ; Rats, Sprague-Dawley ; Humans ; Male ; Time Factors ; Cell Line, Tumor ; Female ; Xenograft Model Antitumor Assays ; Phenylalanine/analogs & derivatives ; Disease Models, Animal

Synergistic cancer treatment with PCuLu nanocatalysts by inducing cuproptosis and enhancing radiotherapy.

Autoren: Yuan P Wang Y Wang A et al.

Quelle: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Dec; Vol. 699 (Pt 2), pp. 138260. Date of Electronic Publication: 2025 Jun 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

MeSH-Schlagworte: Copper*/chemistry , Copper*/pharmacology , Photochemotherapy* , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Photosensitizing Agents*/pharmacology , Photosensitizing Agents*/chemistry , Neoplasms*/drug therapy , Neoplasms*/pathology, Humans ; Catalysis ; X-Rays ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Cell Line, Tumor ; Particle Size

Investigations on bioactive compounds of Punica granatum and Beta vulgaris for breast cancer treatment: Network pharmacology predictions, molecular docking, and in-vitro experimental verification of radiation-sensitizing effects.

Autoren: Sukumaran N Sureka CS Gurusaravanan P et al.

Quelle: Computational biology and chemistry [Comput Biol Chem] 2025 Dec; Vol. 119, pp. 108512. Date of Electronic Publication: 2025 May 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

MeSH-Schlagworte: Pomegranate*/chemistry , Beta vulgaris*/chemistry , Breast Neoplasms*/drug therapy , Breast Neoplasms*/radiotherapy , Network Pharmacology*/methods , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/isolation & purification , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/therapeutic use , Anthocyanins*/chemistry , Anthocyanins*/isolation & purification , Anthocyanins*/pharmacology , Anthocyanins*/therapeutic use , Plant Extracts*/chemistry , Plant Extracts*/isolation & purification , Plant Extracts*/pharmacology, Molecular Docking Simulation ; Humans ; Female ; MDA-MB-231 Cells ; Cell Proliferation/drug effects

Ion-interference amplifier nano-system enhances radiotherapy via mitochondrial dysfunction and efferocytosis Inhibition.

Autoren: Zheng S Zheng Y Hu H et al.

Quelle: Journal of nanobiotechnology [J Nanobiotechnology] 2025 Nov 25; Vol. 23 (1), pp. 737. Date of Electronic Publication: 2025 Nov 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE

MeSH-Schlagworte: Mitochondria*/drug effects , Mitochondria*/radiation effects , Mitochondria*/metabolism , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology , Nanoparticles*/chemistry, Animals ; Mice, Inbred BALB C ; Mice ; Cell Line, Tumor ; Female ; Manganese/chemistry ; Tumor Microenvironment/drug effects ; Apoptosis/drug effects ; Calcium/chemistry ; Phagocytosis/drug effects ; Hyaluronic Acid/chemistry ; Efferocytosis

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer.

Autoren: Haines BJ Kreamer M Benej M et al.

Quelle: Journal of medicinal chemistry [J Med Chem] 2025 Nov 13; Vol. 68 (21), pp. 23140-23162. Date of Electronic Publication: 2025 Oct 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Papaverine*/pharmacology , Papaverine*/chemistry , Papaverine*/analogs & derivatives , Papaverine*/chemical synthesis , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemical synthesis , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/therapeutic use , Electron Transport Complex I*/antagonists & inhibitors, Animals ; Mice ; Female ; Cell Line, Tumor ; Humans ; Structure-Activity Relationship ; Solubility ; Mammary Neoplasms, Experimental/radiotherapy ; Mammary Neoplasms, Experimental/drug therapy

Intracellular Disulfide Stress Induced Actin Dysfunction for Enhancing Radiotherapy Sensitivity and Eliciting Antitumor Immunity.

Autoren: Liu Y Zhang C Deng Z et al.

Quelle: ACS nano [ACS Nano] 2025 Nov 11; Vol. 19 (44), pp. 38669-38684. Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

MeSH-Schlagworte: Disulfides*/chemistry , Disulfides*/metabolism , Actins*/metabolism , Radiation Tolerance*/drug effects , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Neoplasms*/radiotherapy, Mice ; Humans ; Animals ; Cell Line, Tumor

Photodynamic treatment in glioma: Metabolic and structural evaluation after therapy.

Autoren: Teixeira MG Marcolino LMC Pinto JG et al.

Quelle: Photochemistry and photobiology [Photochem Photobiol] 2025 Nov-Dec; Vol. 101 (6), pp. 1380-1391. Date of Electronic Publication: 2025 Sep 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Photobiology Country of Publication: United States NLM ID: 0376425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-1097 (Electronic) Linking ISSN: 00318655 NLM ISO Abbreviation: Photochem Photobiol Subsets: MEDLINE

MeSH-Schlagworte: Photochemotherapy* , Gliosarcoma*/drug therapy , Gliosarcoma*/pathology , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/therapeutic use , Chlorophyllides*/pharmacology , Chlorophyllides*/therapeutic use , Central Nervous System Neoplasms*/drug therapy , Central Nervous System Neoplasms*/pathology, Membrane Potential, Mitochondrial/drug effects ; Cytoskeleton/drug effects ; Cytoskeleton/ultrastructure ; Benzimidazoles/chemistry ; Carbocyanines/chemistry ; Rhodamine 123/chemistry ; Apoptosis/drug effects ; Flow Cytometry ; Fluorescent Dyes/chemistry ; Microscopy, Electron, Scanning ; Humans

Novel pyrrole-sulfonamide derivatives as EGFR inhibitors and radiosensitizers in lung cancer.

Autoren: El-Gazzar MGM Zahran SS Ghorab MM et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Nov; Vol. 166, pp. 109173. Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Sulfonamides*/chemical synthesis , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Lung Neoplasms*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Pyrroles*/chemistry , Pyrroles*/pharmacology , Pyrroles*/chemical synthesis , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/chemical synthesis, Humans ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/metabolism ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Molecular Docking Simulation ; Cell Line, Tumor

Safety and Potential Radiosensitizing Effect of Olaparib in Combination With Breast Radiation Therapy for Patients With Triple-Negative Breast Cancer With Residual Disease: Long-Term Results From the RADIOPARP Phase 1 Trial.

Autoren: Loap P Loirat D Stern MH et al.

Quelle: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Nov 01; Vol. 123 (3), pp. 726-731. Date of Electronic Publication: 2025 May 18.

Publikationsart: Journal Article; Clinical Trial, Phase I

Info zur Zeitschrift: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/radiotherapy , Triple Negative Breast Neoplasms*/therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/mortality , Triple Negative Breast Neoplasms*/genetics , Phthalazines*/adverse effects , Phthalazines*/therapeutic use , Phthalazines*/administration & dosage , Piperazines*/adverse effects , Piperazines*/therapeutic use , Piperazines*/administration & dosage , Radiation-Sensitizing Agents*/therapeutic use , Radiation-Sensitizing Agents*/adverse effects , Poly(ADP-ribose) Polymerase Inhibitors*/adverse effects , Poly(ADP-ribose) Polymerase Inhibitors*/therapeutic use , Chemoradiotherapy*/adverse effects , Chemoradiotherapy*/methods, Humans ; Female ; Middle Aged ; Neoplasm, Residual ; Adult ; Aged ; Neoplasm Recurrence, Local ; Combined Modality Therapy

HSA-templated synergistic platform boosts radiotherapy via enhanced radiosensitization and ferroptosis induction.

Autoren: Fan X Liu J Xie S et al.

Quelle: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2025 Nov; Vol. 83, pp. 101293. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9815369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2084 (Electronic) Linking ISSN: 13687646 NLM ISO Abbreviation: Drug Resist Updat Subsets: MEDLINE

MeSH-Schlagworte: Ferroptosis*/drug effects , Ferroptosis*/radiation effects , Radiation-Sensitizing Agents*/administration & dosage , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Neoplasms*/radiotherapy , Neoplasms*/pathology , Neoplasms*/immunology, Humans ; Animals ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology ; Tumor Microenvironment/radiation effects ; Mice ; Radiation Tolerance/drug effects ; Cell Line, Tumor ; Nanoparticles/chemistry ; Nanoparticles/administration & dosage ; Folic Acid/chemistry ; Folic Acid/analogs & derivatives ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/drug effects ; Lipid Peroxidation/drug effects ; Oxidative Stress/drug effects ; Polyethylene Glycols/chemistry ; Xenograft Model Antitumor Assays ; Dendritic Cells/drug effects ; Dendritic Cells/immunology

A multifunctional curcumin-Fe 3 O 4 @ZIF-8 nanoformulation as a T2 MRI contrast agent and pH-responsive theranostic platform for targeted ROS generation, radiosensitization, and triple-negative breast cancer treatment.

Autoren: Rahmani A Maleki A Jafari R et al.

Quelle: Journal of materials chemistry. B [J Mater Chem B] 2025 Oct 29; Vol. 13 (42), pp. 13805-13829. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-7518 (Electronic) Linking ISSN: 2050750X NLM ISO Abbreviation: J Mater Chem B Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/diagnostic imaging , Triple Negative Breast Neoplasms*/metabolism , Reactive Oxygen Species*/metabolism , Curcumin*/chemistry , Curcumin*/pharmacology , Contrast Media*/chemistry , Contrast Media*/pharmacology , Theranostic Nanomedicine* , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Metal-Organic Frameworks*/chemistry, Humans ; Hydrogen-Ion Concentration ; Magnetic Resonance Imaging ; Apoptosis/drug effects ; Female ; Animals ; Cell Line, Tumor ; Mice ; Drug Screening Assays, Antitumor ; Cell Proliferation/drug effects ; Particle Size ; Cell Survival/drug effects ; Imidazoles

A multifunctional nanotheranostic: hyaluronic acid-squalene nanoclusters for radiosensitization, ferroptosis, and Mn/Fe-based dual MR imaging.

Autoren: Nagareddy R Chahal S Vasvani S et al.

Quelle: Biomaterials science [Biomater Sci] 2025 Oct 21; Vol. 13 (21), pp. 6113-6126. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

MeSH-Schlagworte: Ferroptosis*/drug effects , Hyaluronic Acid*/chemistry , Hyaluronic Acid*/pharmacology , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology , Magnetic Resonance Imaging*/methods , Nanoparticles*/chemistry, Animals ; Humans ; Mice ; Manganese/chemistry ; Ferric Compounds/chemistry ; Cell Line, Tumor ; Manganese Compounds/chemistry ; Theranostic Nanomedicine ; Iron/chemistry ; Reactive Oxygen Species/metabolism ; Contrast Media/chemistry ; Colonic Neoplasms/diagnostic imaging ; Mice, Nude ; Mice, Inbred BALB C

The physicochemical and biochemical mechanisms of porphyrinoid-mediated radiodynamic therapy.

Autoren: Leo S Carigga Gutierrez NM Bulin AL et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Oct 15; Vol. 296, pp. 117861. Date of Electronic Publication: 2025 Jun 16.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Porphyrins*/chemistry , Porphyrins*/pharmacology , Porphyrins*/therapeutic use , Photosensitizing Agents*/chemistry , Photosensitizing Agents*/pharmacology , Neoplasms*/radiotherapy , Neoplasms*/drug therapy , Radiation-Sensitizing Agents*/chemistry , Radiation-Sensitizing Agents*/pharmacology, Humans ; Animals ; Molecular Structure ; Reactive Oxygen Species/metabolism

JS-K enhances renal cell carcinoma radiosensitivity through the Wnt/β-catenin signaling pathway and inhibits DNA damage repair.

Autoren: Zhao Y Lin X Zeng W et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118514. Date of Electronic Publication: 2025 Aug 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Carcinoma, Renal Cell*/drug therapy , Carcinoma, Renal Cell*/radiotherapy , Kidney Neoplasms*/drug therapy , Kidney Neoplasms*/radiotherapy , Nitric Oxide Donors*/pharmacology , Nitric Oxide Donors*/therapeutic use , Radiation-Sensitizing Agents*/pharmacology , Radiation-Sensitizing Agents*/therapeutic use , Recombinational DNA Repair*/drug effects , Wnt Signaling Pathway*/drug effects, Humans ; Cell Cycle/drug effects ; Cell Line, Tumor ; Radiation Tolerance/drug effects ; Male ; Animals ; Mice ; Mice, Nude ; Mice, Inbred BALB C ; Xenograft Model Antitumor Assays ; Azo Compounds ; Piperazines