Suchergebnisse - "Pulmonary Disease, Chronic Obstructive"

Beyond pulmonary rehabilitation: can the PICk UP programme fill the gap? A randomised trial in COPD.

Autoren: Rebelo P Brooks D Cravo J et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2416827. Date of Electronic Publication: 2024 Oct 24.

Publikationsart: Journal Article; Randomized Controlled Trial; Multicenter Study

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/rehabilitation , Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/psychology , Exercise*/physiology , Exercise Therapy*/methods, Humans ; Male ; Female ; Aged ; Quality of Life ; Middle Aged ; Treatment Outcome ; Muscle Strength/physiology

Treatable moments for smoking cessation in asthma and COPD: a nationwide cohort study.

Autoren: Vauterin D Lang AE Proesmans K et al.

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Dec 04; Vol. 12 (1). Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Smoking Cessation*/methods , Smoking Cessation*/statistics & numerical data , Pulmonary Disease, Chronic Obstructive*/epidemiology , Pulmonary Disease, Chronic Obstructive*/therapy , Asthma*/epidemiology , Tobacco Use Disorder*/therapy, Humans ; Female ; Male ; Middle Aged ; Aged ; Belgium/epidemiology ; Cohort Studies ; Adult

Cost-effectiveness of a self-management maintenance programme following pulmonary rehabilitation: a UK randomised controlled trial for patients with chronic obstructive pulmonary disease.

Autoren: Khan AJ Gumber A Richardson M et al.

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Dec 04; Vol. 12 (1). Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/rehabilitation , Pulmonary Disease, Chronic Obstructive*/economics , Self-Management*/economics , Self-Management*/methods, Humans ; Cost-Benefit Analysis ; Female ; Male ; Aged ; Middle Aged ; United Kingdom ; Quality-Adjusted Life Years ; Prospective Studies

Relationship of material deprivation with emergency or unplanned healthcare utilisation in adults with chronic obstructive pulmonary disease: analysis from an Asthma+Lung UK survey.

Autoren: Adesibikan A Williams PJ Cumella A et al.

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Nov 18; Vol. 12 (1). Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/therapy , Pulmonary Disease, Chronic Obstructive*/epidemiology , Pulmonary Disease, Chronic Obstructive*/economics , Patient Acceptance of Health Care*/statistics & numerical data , Poverty*/statistics & numerical data, Humans ; Female ; Male ; United Kingdom/epidemiology ; Middle Aged ; Aged ; Adult ; Asthma/epidemiology ; Socioeconomic Factors ; Emergency Service, Hospital/statistics & numerical data ; Surveys and Questionnaires

Identifying azithromycin responders with an individual treatment effect model in COPD.

Autoren: Verstraete K Gyselinck I Huts H et al.

Quelle: Thorax [Thorax] 2025 Nov 14; Vol. 80 (12), pp. 900-908. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE

MeSH-Schlagworte: Azithromycin*/therapeutic use , Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/physiopathology , Anti-Bacterial Agents*/therapeutic use, Humans ; Male ; Female ; Aged ; Treatment Outcome ; Middle Aged ; Machine Learning ; Disease Progression

A qualitative study of patient experiences and expectations around hospital care during exacerbations of chronic obstructive pulmonary disease - a health CASCADE study.

Autoren: An Q Sandlund M Schreier M et al.

Quelle: BMC pulmonary medicine [BMC Pulm Med] 2025 Nov 13; Vol. 25 (1), pp. 524. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100968563 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2466 (Electronic) Linking ISSN: 14712466 NLM ISO Abbreviation: BMC Pulm Med Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/therapy , Pulmonary Disease, Chronic Obstructive*/psychology , Hospitalization* , Patient Satisfaction*, Humans ; Qualitative Research ; Male ; Female ; Aged ; Middle Aged ; Disease Progression

Supine hyperinflation and expiratory flow limitation are associated with respiratory arousals and nocturnal hypoventilation in COPD.

Autoren: Srinivasan M Touma D Blokland KEC et al.

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Nov 05; Vol. 12 (1). Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/complications , Hypoventilation*/physiopathology , Hypoventilation*/etiology , Arousal*/physiology, Humans ; Male ; Female ; Aged ; Prospective Studies ; Middle Aged ; Polysomnography ; Supine Position/physiology ; Pulmonary Gas Exchange/physiology ; Exhalation ; Inspiratory Capacity ; Respiratory Mechanics/physiology

Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients (TELE-TOC): a study protocol for a type II hybrid effectiveness-implementation randomised, pragmatic clinical trial of a pharmacist-led intervention.

Autoren: Ramadurai D Lee CT Traeger L et al.

Quelle: BMJ open [BMJ Open] 2025 Nov 04; Vol. 15 (11), pp. e105521. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article; Clinical Trial Protocol

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/therapy , Pulmonary Disease, Chronic Obstructive*/drug therapy , Telemedicine* , Pharmacists* , Patient Education as Topic*/methods , Transitional Care*/organization & administration, Humans ; Pragmatic Clinical Trials as Topic ; Female

Predicting response to inhaled corticosteroid maintenance therapy in patients with chronic obstructive pulmonary disease using machine learning models.

Autoren: Wu SC Wu CY Chien JY et al.

Quelle: Respiratory medicine [Respir Med] 2025 Nov; Vol. 248, pp. 108378. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/physiopathology , Machine Learning* , Adrenal Cortex Hormones*/administration & dosage , Adrenal Cortex Hormones*/therapeutic use, Humans ; Male ; Female ; Administration, Inhalation ; Aged ; Middle Aged ; Treatment Outcome ; ROC Curve ; Eosinophils

Real-life impact of anti-IL5 therapy on exacerbation types in patients with obstructive lung disease.

Autoren: Vanfleteren LEGW Vauterin D Lahousse L

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Oct 22; Vol. 12 (1). Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/complications , Pulmonary Disease, Chronic Obstructive*/epidemiology , Antibodies, Monoclonal, Humanized*/therapeutic use , Interleukin-5*/antagonists & inhibitors , Asthma*/drug therapy , Anti-Asthmatic Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Disease Progression ; Belgium/epidemiology ; Adrenal Cortex Hormones/therapeutic use ; Smoking/epidemiology ; Adult ; Hospitalization/statistics & numerical data ; Treatment Outcome

Sputum colour charts to guide antibiotic self-treatment of acute exacerbation of chronic obstructive pulmonary disease: the Colour-COPD RCT.

Autoren: Gkini E De Soyza J Spittle DA et al.

Quelle: BMJ open respiratory research [BMJ Open Respir Res] 2025 Oct 10; Vol. 12 (1). Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article; Multicenter Study; Randomized Controlled Trial; Pragmatic Clinical Trial

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/microbiology , Pulmonary Disease, Chronic Obstructive*/diagnosis , Sputum*/microbiology , Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/administration & dosage , Self-Management*/methods, Humans ; Male ; Female ; Aged ; Middle Aged ; Color ; Quality of Life ; Disease Progression ; United Kingdom ; Hospitalization/statistics & numerical data

Productivity benefits of chronic obstructive pulmonary disease prevention in China.

Autoren: Zhu Y Li Z Chen S et al.

Quelle: BMC public health [BMC Public Health] 2025 Oct 03; Vol. 25 (1), pp. 3312. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100968562 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2458 (Electronic) Linking ISSN: 14712458 NLM ISO Abbreviation: BMC Public Health Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/prevention & control , Pulmonary Disease, Chronic Obstructive*/economics , Pulmonary Disease, Chronic Obstructive*/epidemiology , Efficiency*, Humans ; China/epidemiology ; Male ; Middle Aged ; Female ; Adult ; Young Adult ; Life Tables

Jianpi Yifei Tongluo recipe attenuates inflammation by promoting the expression of interferon regulatory factor 4 in the rat model of chronic obstructive pulmonary disease.

Autoren: Wei W Qi L Ling FU et al.

Quelle: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2025 Oct; Vol. 45 (5), pp. 1048-1058.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academy Of Traditional Chinese Medicine Country of Publication: China NLM ID: 8211546 Publication Model: Print Cited Medium: Internet ISSN: 2589-451X (Electronic) Linking ISSN: 02552922 NLM ISO Abbreviation: J Tradit Chin Med Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/genetics , Pulmonary Disease, Chronic Obstructive*/immunology , Pulmonary Disease, Chronic Obstructive*/metabolism , Drugs, Chinese Herbal*/administration & dosage , Interferon Regulatory Factors*/genetics , Interferon Regulatory Factors*/immunology, Animals ; Rats, Sprague-Dawley ; Rats ; Male ; Disease Models, Animal ; Humans ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; Lung/drug effects ; Lung/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology

Liquid chromatography-mass spectrometry-based metabolomics study of the protective mechanism of Shenji Guben decoction on chronic obstructive pulmonary disease.

Autoren: Tingyu P Jing Y Yue GE et al.

Quelle: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2025 Oct; Vol. 45 (5), pp. 1009-1018.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academy Of Traditional Chinese Medicine Country of Publication: China NLM ID: 8211546 Publication Model: Print Cited Medium: Internet ISSN: 2589-451X (Electronic) Linking ISSN: 02552922 NLM ISO Abbreviation: J Tradit Chin Med Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/metabolism , Pulmonary Disease, Chronic Obstructive*/genetics , Drugs, Chinese Herbal*/administration & dosage , Protective Agents*/administration & dosage, Animals ; Metabolomics ; Mice ; Male ; Humans ; Mass Spectrometry ; Chromatography, Liquid ; Mice, Inbred C57BL ; Lung/drug effects ; Lung/metabolism ; Disease Models, Animal ; Female ; Liquid Chromatography-Mass Spectrometry

Electrovest®: A novel portable electro-vibratory device for airway clearance in chronic hypersecretory lung diseases.

Autoren: Rivilla Rivilla R Méndez Alonso AY Roque Betancourt E et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2594888. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Vibration*/therapeutic use , Electric Stimulation Therapy*/instrumentation , Electric Stimulation Therapy*/methods , Pulmonary Disease, Chronic Obstructive*/therapy , Pulmonary Disease, Chronic Obstructive*/physiopathology , Lung Diseases*/therapy , Lung Diseases*/physiopathology, Humans ; Cross-Over Studies ; Female ; Male ; Pilot Projects ; Middle Aged ; Aged ; Chronic Disease ; Treatment Outcome ; Sputum/metabolism ; Adult ; Bronchiectasis/therapy ; Cystic Fibrosis/therapy ; Cystic Fibrosis/physiopathology

Prognostic implications of cluster-defined phenotypes in AECOPD patients with bronchiectasis: A multicenter study.

Autoren: Pu J Luo Y Wei H et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2591498. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Bronchiectasis*/mortality , Bronchiectasis*/complications , Bronchiectasis*/epidemiology , Pulmonary Disease, Chronic Obstructive*/mortality , Pulmonary Disease, Chronic Obstructive*/complications , Pulmonary Disease, Chronic Obstructive*/physiopathology, Humans ; Male ; Female ; Aged ; Prognosis ; Phenotype ; Prospective Studies ; Middle Aged ; Cluster Analysis ; Length of Stay/statistics & numerical data ; Disease Progression ; China/epidemiology ; Hospitalization/statistics & numerical data ; Respiration, Artificial/statistics & numerical data ; Propensity Score ; Intensive Care Units/statistics & numerical data ; Noninvasive Ventilation/statistics & numerical data

Effects of asymmetric nasal high-flow cannula on carbon dioxide in hypercapnic patients: A randomised crossover physiological pilot study.

Autoren: Pisani L Vega ML Ageno E et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2411813. Date of Electronic Publication: 2024 Nov 05.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Hypercapnia*/therapy , Hypercapnia*/etiology , Hypercapnia*/physiopathology , Pulmonary Disease, Chronic Obstructive*/therapy , Pulmonary Disease, Chronic Obstructive*/complications , Pulmonary Disease, Chronic Obstructive*/physiopathology , Cannula* , Carbon Dioxide*/blood , Oxygen Inhalation Therapy*/instrumentation , Oxygen Inhalation Therapy*/methods , Noninvasive Ventilation*/instrumentation , Noninvasive Ventilation*/methods, Humans ; Cross-Over Studies ; Male ; Pilot Projects ; Female ; Aged ; Prospective Studies ; Middle Aged

Physiological effects of nasal high flow therapy during exercise in patients with chronic obstructive pulmonary disease: A crossover randomised controlled trial.

Autoren: Bonnevie T Gravier FE Smondack P et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2424649. Date of Electronic Publication: 2024 Nov 20.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/therapy , Oxygen Inhalation Therapy*/methods , Exercise*/physiology, Humans ; Cross-Over Studies ; Male ; Female ; Middle Aged ; Single-Blind Method ; Aged ; Dyspnea/physiopathology ; Dyspnea/therapy ; Dyspnea/etiology ; Exercise Test/methods ; Respiratory Muscles/physiopathology ; Exercise Tolerance/physiology ; Tidal Volume

Associations of pre-COPD indicators with lung function decline and their longitudinal transitions.

Autoren: Fan J Cong S Zhang Y et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2486881. Date of Electronic Publication: 2025 May 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/epidemiology , Pulmonary Disease, Chronic Obstructive*/diagnosis , Bronchitis, Chronic*/physiopathology , Bronchitis, Chronic*/epidemiology , Lung*/physiopathology, Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Forced Expiratory Volume ; Spirometry/methods ; China/epidemiology ; Vital Capacity/physiology ; Aged ; Longitudinal Studies ; Disease Progression ; Smoking/adverse effects ; Smoking/epidemiology ; Respiratory Function Tests/methods ; Peak Expiratory Flow Rate/physiology

Effect of exercise training on modulating the TH17/TREG imbalance in individuals with severe COPD: A randomized controlled trial.

Autoren: Ito JT Alves LHV Oliveira LM et al.

Quelle: Pulmonology [Pulmonology] 2025 Dec 31; Vol. 31 (1), pp. 2441069. Date of Electronic Publication: 2025 Jan 07.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101723786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-0437 (Electronic) Linking ISSN: 25310429 NLM ISO Abbreviation: Pulmonology Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/immunology , Pulmonary Disease, Chronic Obstructive*/rehabilitation , Pulmonary Disease, Chronic Obstructive*/physiopathology , Th17 Cells*/immunology , T-Lymphocytes, Regulatory*/immunology , Muscle Strength*/physiology , Exercise Therapy*/methods, Humans ; Male ; Female ; Aged ; Middle Aged ; Severity of Illness Index ; Exercise/physiology ; Walk Test/methods ; Resistance Training/methods ; Treatment Outcome ; Inflammation/immunology ; Exercise Tolerance/physiology ; Physical Fitness/physiology