Search Results - "Proteomics methods"

To Fly, or Not to Fly, That Is the Question: A Deep Learning Model for Peptide Detectability Prediction in Mass Spectrometry

Authors: Naim Abdul-Khalek Mario Picciani Omar Shouman et al.

Source: J Proteome Res
Abdul-Khalek, N, Picciani, M, Shouman, O, Wimmer, R, Overgaard, M T, Wilhelm, M & Gregersen Echers, S 2025, 'To Fly, or Not to Fly, That Is the Question : A Deep Learning Model for Peptide Detectability Prediction in Mass Spectrometry', Journal of Proteome Research, vol. 24, no. 6, pp. 2709-2726. https://doi.org/10.1021/acs.jproteome.4c00973

Subject Terms: Attention mechanism, Computational proteomics, Encoder-decoder, Peptides/analysis, Classification, Article, ddc, Flyability, Rescoring, Deep Learning, Bottom-up proteomics, Peptide Library, ddc:630, Animals, Humans, Amino Acid Sequence, Proteomics/methods, Peptide detectability, Mass Spectrometry/methods, Software

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40344201
https://mediatum.ub.tum.de/doc/1784920/document.pdf

A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease

Authors: Jelle Vehof Amber Rhee Niccolò Rossi et al.

Source: Vehof, J, Rhee, A, Rossi, N, Falchi, M, Hammond, C J & Williams, F M K 2025, ' A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease ', OCULAR SURFACE, vol. 36, pp. 198-208 . https://doi.org/10.1016/j.jtos.2025.01.011

Subject Terms: Inflammation/blood, Serum, Male, Proteomics, Adult, Aged, 80 and over, Inflammation, Middle Aged, Dry Eye Syndromes/blood, Young Adult, Surveys and Questionnaires, Autoimmune disease, Cytokines, Humans, Dry Eye Syndromes, Female, Dry eye disease, Proteomics/methods, Chemokines, Biomarkers/blood, Neurotrophin-3, Biomarkers, Aged

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39884388
https://hdl.handle.net/11370/1273994c-b806-4497-9c96-b78cc5bca189
https://research.rug.nl/en/publications/1273994c-b806-4497-9c96-b78cc5bca189
https://doi.org/10.1016/j.jtos.2025.01.011
https://kclpure.kcl.ac.uk/ws/files/340205500/1-s2.0-S1542012425000199-main.pdf

An overview of quantitative proteomic approaches

Authors: Kumar, Neelesh Parida, Satya Narayan Tripathy, Partha Sarathi et al.

Source: Advances in omics technologies. :219-245

Subject Terms: Animal protein, Proteomics, Proteomics: methods, Quantitative proteomic

File Description: print

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-246999

Plasma proteome variation and its genetic determinants in children and adolescents

Authors: Lili Niu Sara Elizabeth Stinson Louise Aas Holm et al.

Source: Nat Genet
Niu, L, Stinson, S E, Holm, L A, Lund, M A V, Fonvig, C E, Cobuccio, L, Meisner, J, Juel, H B, Fadista, J, Thiele, M, Krag, A, Holm, J C, Rasmussen, S, Hansen, T & Mann, M 2025, ' Plasma proteome variation and its genetic determinants in children and adolescents ', Nature Genetics, vol. 57, pp. 635–646 . https://doi.org/10.1038/s41588-025-02089-2

Subject Terms: Male, Proteomics, Adult, Adolescent, Proteome, Quantitative Trait Loci, Genetic Variation, Blood Proteins, Mendelian Randomization Analysis, Article, Body Mass Index, Proteome/genetics, Blood Proteins/genetics, Humans, Female, Proteomics/methods, Child

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39972214
https://curis.ku.dk/ws/files/451268461/Plasma_proteome.pdf
https://portal.findresearcher.sdu.dk/da/publications/68814f0c-b2e0-465e-819f-66ceb0f65beb
https://doi.org/10.1038/s41588-025-02089-2

Interaction and regulation of the mitochondrial proteome – in health and disease

Authors: Palmfeldt, Johan

Source: Palmfeldt, J 2025, 'Interaction and regulation of the mitochondrial proteome-in health and disease', Expert Review of Proteomics, vol. 22, no. 1, pp. 19-33. https://doi.org/10.1080/14789450.2025.2451704

Subject Terms: Proteomics, Mitochondrial Proteins/metabolism, Proteome, Proteome/metabolism, oxidative phosphorylation, stress response, NAD, kynurenine, Mitochondria, Mitochondrial Proteins, proteomics, Neoplasms, Mitochondria/metabolism, metabolic disorders, Humans, Animals, biomarker panels, Proteomics/methods, Mitochondrion, Energy Metabolism

Access URL: https://pubmed.ncbi.nlm.nih.gov/39806765

Multiomics approach provides insight into altered choline metabolism and liver injury in patients with glycogen storage disease type Ia

Authors: Pirozzi, Francesca Amiri, Ramin Luni, Camilla et al.

Source: Sci Rep

Subject Terms: Male, Liver/metabolism, Adult, Adolescent, Choline/metabolism, ALDOB, Serum biomarkers, Liver injury, Multiomics, Glycogen Storage Disease Type I/metabolism, Article, Young Adult, Glycogen storage disease type Ia, Lipid metabolism, Humans, Metabolomics/methods, Female, Proteomics/methods, Child, Biomarkers/blood

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Access URL: https://hdl.handle.net/11588/1011755
https://research.rug.nl/en/publications/694c167a-a793-493c-a97e-a9e3d7426525
https://hdl.handle.net/11370/694c167a-a793-493c-a97e-a9e3d7426525
https://doi.org/10.1038/s41598-025-06272-7
https://hdl.handle.net/11588/1011755
https://doi.org/10.1038/s41598-025-06272-7
https://www.nature.com/articles/s41598-025-06272-7
https://hdl.handle.net/11585/1019735
https://doi.org/10.1038/s41598-025-06272-7

N-Terminal Proteomics Reveals Distinct Protein Degradation Patterns in Different Types of Human Atherosclerotic Plaques

Authors: Lasse G. Lorentzen Karin Yeung Auguste Zitkeviciute et al.

Source: Lorentzen, L G, Yeung, K, Zitkeviciute, A, Yang-Jensen, K C, Eldrup, N, Eiberg, J P & Davies, M J 2025, ' N-Terminal Proteomics Reveals Distinct Protein Degradation Patterns in Different Types of Human Atherosclerotic Plaques ', Journal of Proteome Research, vol. 24, no. 1, pp. 144-157 . https://doi.org/10.1021/acs.jproteome.4c00548

Subject Terms: Atherosclerotic/metabolism, Peptide Fragments/metabolism, Proteomics, Male, Chromatography, Liquid, Peptide Hydrolases/metabolism, Extracellular Matrix/metabolism, Middle Aged, Plaque, Atherosclerotic, Peptide Fragments, Mass Spectrometry, Extracellular Matrix, Cross-Sectional Studies, Proteolysis, Humans, Plaque, Atherosclerotic/metabolism, Female, Carotid Stenosis, Proteomics/methods, Carotid Stenosis/metabolism, Plaque, Chromatography, Liquid, Aged, Peptide Hydrolases

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39665830
https://curis.ku.dk/ws/files/432831587/N_Terminal_pro.pdf

Evaluating the performance of multi-omics integration: a thyroid toxicity case study

Authors: Sebastian Canzler Kristin Schubert Ulrike E. Rolle-Kampczyk et al.

Source: Arch Toxicol

Subject Terms: Proteomics, Male, Thyroid Gland/metabolism [MeSH], Proteomics/methods [MeSH], Thyroid Gland/drug effects [MeSH], Risk Assessment [MeSH], Humans [MeSH], Risk assessment, Rats [MeSH], Thyroid Gland/pathology [MeSH], Transcriptome/drug effects [MeSH], Genomics/methods [MeSH], Data integration, Animals [MeSH], Chemical exposure, Toxicogenomics and Omics Technologies, Multi-omics, Multiomics [MeSH], Toxicology, Male [MeSH], Metabolomics/methods [MeSH], Toxicity Tests/methods [MeSH], Thyroid Gland, Genomics, Multiomics, Risk Assessment, Rats, Toxicity Tests, Animals, Metabolomics, Humans, Transcriptome

Access URL: https://pubmed.ncbi.nlm.nih.gov/39441382
https://repository.publisso.de/resource/frl:6502259

Proteomic Profiling of Lymph Nodes Differentiates Classic Hodgkin Lymphoma With and Without Skeletal Involvement

Authors: Maja Dam Andersen Katharina Wolter Marie Beck Hairing Enemark et al.

Source: Eur J Haematol
Andersen, M D, Wolter, K, Enemark, M B H, Pedersen, M A, Gormsen, L C, Lauridsen, K L, Starklint, J, Hamilton-Dutoit, S J, d'Amore, F, Ludvigsen, M, Honoré, B & Kamper, P 2025, 'Proteomic Profiling of Lymph Nodes Differentiates Classic Hodgkin Lymphoma With and Without Skeletal Involvement', European Journal of Haematology, vol. 114, no. 1, pp. 173-185. https://doi.org/10.1111/ejh.14326

Subject Terms: Male, Proteomics, Adult, Hodgkin Disease/diagnosis, Proteome, Bone Neoplasms, Bone Neoplasms/diagnosis, Middle Aged, classic Hodgkin lymphoma (CHL), Prognosis, bone, Hodgkin Disease, proteomics, Biomarkers, Tumor/metabolism, Positron Emission Tomography Computed Tomography, Lymph Nodes/pathology, Biomarkers, Tumor, Humans, Original Article, Female, Lymph Nodes, Proteomics/methods, nLC-MS/MS, Aged

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39394762
https://pure.au.dk/ws/files/434179323/European_J_of_Haematology_-_2024_-_Andersen_-_Proteomic_Profiling_of_Lymph_Nodes_Differentiates_Classic_Hodgkin_Lymphoma.pdf
http://www.scopus.com/inward/record.url?scp=85206086991&partnerID=8YFLogxK
https://doi.org/10.1111/ejh.14326
https://pure.au.dk/ws/files/434179323/European_J_of_Haematology_-_2024_-_Andersen_-_Proteomic_Profiling_of_Lymph_Nodes_Differentiates_Classic_Hodgkin_Lymphoma.pdf
https://pure.au.dk/portal/en/publications/7b7dcf89-f4c5-48bc-a0c2-2b2cba276800

A proteomic approach supports the clinical relevance of TAT-Cx43266-283 in glioblastoma

Authors: Sara G. Pelaz Raquel Flores-Hernández Tatjana Vujic et al.

Source: Translational research, vol. 272, pp. 95-110

Subject Terms: Glioblastoma/metabolism, Glioblastoma/pathology, Humans, Proteomics/methods, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Cell Line, Tumor, src-Family Kinases/metabolism, Clinical Relevance, Brain tumors, Cell-penetrating peptides, Connexin, Glioblastoma, Proteomics, Src, src-Family Kinases, Brain Neoplasms

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Access URL: https://pubmed.ncbi.nlm.nih.gov/38876188
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_61BEB1A329563
https://serval.unil.ch/notice/serval:BIB_61BEB1A32956
https://serval.unil.ch/resource/serval:BIB_61BEB1A32956.P001/REF.pdf

An integrated multi-omics analysis of the effects of the food processing-induced contaminant 2-monochloropropane-1,3-diol (2-MCPD) in rat heart

Authors: Lucien G. J. Cayer Thorsten Buhrke Jennifer Roberts et al.

Source: Arch Toxicol

Subject Terms: Male, Proteomics, Myocardium, alpha-Chlorohydrin, Food Contamination, Heart, Toxicogenomics and Omics Technologies, Multiomics, Rats, Inbred F344, Cardiotoxicity, Rats, Oxylipin, Rats, Inbred F344 [MeSH], Cardiotoxicity/etiology [MeSH], Proteomics/methods [MeSH], Tandem Mass Spectrometry [MeSH], Food Contamination [MeSH], Proteome, Rats [MeSH], Transcriptome/drug effects [MeSH], Animals [MeSH], Heart/drug effects [MeSH], Multi-omics, Multiomics [MeSH], Male [MeSH], Transcriptome, alpha-Chlorohydrin/toxicity [MeSH], Lipidomics [MeSH], 2-MCPD, Oxylipins [MeSH], Myocardium/metabolism [MeSH], Tandem Mass Spectrometry, Lipidomics, Animals, Oxylipins

Access URL: https://pubmed.ncbi.nlm.nih.gov/39316134
https://repository.publisso.de/resource/frl:6508394

Towards characterization of cell culture conditions for reliable proteomic analysis: in vitro studies on A549, differentiated THP-1, and NR8383 cell lines

Authors: Rico Ledwith Tobias Stobernack Antje Bergert et al.

Source: Arch Toxicol
Archives of Toxicology

Subject Terms: Proteomics, Proteome, Proteomics/methods [MeSH], Macrophages/drug effects [MeSH], Humans [MeSH], Cell Differentiation/drug effects [MeSH], Cell Line [MeSH], Rats [MeSH], Macrophages/metabolism [MeSH], THP-1 Cells [MeSH], Animals [MeSH], New approach methodologies (NAMs), Toxicity mechanisms, Cell culture conditions, Passage numbers, Toxicogenomics and Omics Technologies, Reproducibility of Results [MeSH], Cell Culture Techniques [MeSH], Oxidative Stress/drug effects [MeSH], THP-1 differentiation process, Proteome [MeSH], THP-1 Cells, Macrophages, Cell Culture Techniques, Reproducibility of Results, Cell Differentiation, Cell Line, Rats, Oxidative Stress, Biowissenschaften, Biologie, Humans, Animals

Access URL: https://pubmed.ncbi.nlm.nih.gov/39264451
https://repository.publisso.de/resource/frl:6508286

Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis

Authors: Jochum, Kristina Miccoli, Andrea Sommersdorf, Cornelia et al.

Source: Arch Toxicol

Subject Terms: Kidney/drug effects [MeSH], Omics, Liver/metabolism [MeSH], Cell Line [MeSH], Cytochrome P-450 CYP1A2/genetics [MeSH], Liver/drug effects [MeSH], Pesticides, Risk Assessment/methods [MeSH], Computational Biology [MeSH], RPTEC, Regulatory Toxicology, Pathway analysis, Toxicity Tests/methods [MeSH], Proteomics/methods [MeSH], Cytochrome P-450 CYP1A2/metabolism [MeSH], Gene enrichment, Kidney/metabolism [MeSH], HepaRG, Humans [MeSH], Transcriptome/drug effects [MeSH], Cytochrome P-450 CYP1A1/genetics [MeSH], Reproducibility of Results [MeSH], Cytochrome P-450 CYP1A1/metabolism [MeSH], Proteome/drug effects [MeSH], Pesticides/toxicity [MeSH], Proteomics, 0301 basic medicine, 0303 health sciences, Proteome, Computational Biology, Reproducibility of Results, HepaRG, RPTEC, Omics, Pathway analysis, Gene enrichment, Pesticides, Kidney, Risk Assessment, Cell Line, 03 medical and health sciences, Liver, Cytochrome P-450 CYP1A2, Toxicity Tests, Cytochrome P-450 CYP1A1, Humans, Transcriptome

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39207506
https://hdl.handle.net/20.500.14243/494026
https://doi.org/10.1007/s00204-024-03839-7
https://repository.publisso.de/resource/frl:6505978

Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases

Authors: Maja Thiele Ida Falk Villesen Lili Niu et al.

Source: Thiele, M, Villesen, I F, Niu, L, Johansen, S, Sulek, K, Nishijima, S, Espen, L V, Keller, M, Israelsen, M, Suvitaival, T, Zawadzki, A D, Juel, H B, Brol, M J, Stinson, S E, Huang, Y, Silva, M C A, Kuhn, M, Anastasiadou, E, Leeming, D J, Karsdal, M, Matthijnssens, J, Arumugam, M, Dalgaard, L T, Legido-Quigley, C, Mann, M, Trebicka, J, Bork, P, Jensen, L J, Hansen, T, Krag, A, MicrobLiver Consortium & GALAXY Consortium 2024, ' Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases ', Journal of Hepatology, vol. 81, no. 2, pp. 345-359 . https://doi.org/10.1016/j.jhep.2024.03.035
Journal of Hepatology

Subject Terms: Proteomics, viromics, microbiome, ALCOHOL, Biomarkers/analysis, GUT MICROBIOME, VALIDATION, 1117 Public Health and Health Services, VIROME, proteomics, Genetics, Metabolomics/methods, FIBROSIS, Humans, Metabolomics, genetics, GENOME-WIDE ASSOCIATION, GALAXY consortium, Fatty Liver/diagnosis, metagenomics, Science & Technology, metatranscriptomics, Gastroenterology & Hepatology, Non-invasive test, NONALCOHOLIC STEATOHEPATITIS, 3202 Clinical sciences, INCREASED INTESTINAL PERMEABILITY, 1103 Clinical Sciences, Genomics, metabolomics, Genomics/methods, 3. Good health, Fatty Liver, SYSTEMS BIOLOGY, lipidomics, MicrobLiver consortium, Viromics, MULTI-OMICS, Metagenomics, Microbiome, Proteomics/methods, Life Sciences & Biomedicine, Biomarkers

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Access URL: https://pubmed.ncbi.nlm.nih.gov/38552880
https://lirias.kuleuven.be/handle/20.500.12942/740356
https://doi.org/10.1016/j.jhep.2024.03.035
https://curis.ku.dk/ws/files/400206035/1_s2.0_S0168827824002198_main.pdf
https://portal.findresearcher.sdu.dk/da/publications/14c4e941-2b9a-403a-9206-c88f75ebec1f
https://doi.org/10.1016/j.jhep.2024.03.035

Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

Authors: van Bergen, Wouter Baggelaar, Marc P. Heck, Albert J. R. et al.

Source: ACS Chem Biol
ACS Chemical Biology

Subject Terms: Proteomics, 0301 basic medicine, 0303 health sciences, Bioorthogonal chemistry, Binding Sites, Proteome, EGFR, Drugs, ErbB Receptors, 03 medical and health sciences, Humans, ABPP, ErbB Receptors Metabolism Antagonists & Inhibitors Chemistry, Protein Binding, Protein Kinase Inhibitors Pharmacology Metabolism Chemistry, Proteomics Methods, Proteome Metabolism, Protein Kinase Inhibitors

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39052621

Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lipid remodeling in lung adenocarcinoma progression

Authors: Sajic, Tatjana Vizovišek, Matej Arni, Stephan et al.

Contributors: Sajic, Tatjana Vizovišek, Matej Arni, Stephan et al.

Source: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-24 (2025)
Nature communications, vol. 16, no. 1, pp. 4889
Nature Communications, 16 (1)

Subject Terms: Humans, Lung Neoplasms/pathology, Lung Neoplasms/metabolism, Lung Neoplasms/enzymology, Adenocarcinoma of Lung/pathology, Adenocarcinoma of Lung/metabolism, Adenocarcinoma of Lung/genetics, Adenocarcinoma of Lung/enzymology, Proteomics/methods, Disease Progression, Mass Spectrometry/methods, Proteome/metabolism, Lipid Metabolism, 10255 Clinic for Thoracic Surgery, 1300 General Biochemistry, Genetics and Molecular Biology, Science, 610 Medicine & health, 1600 General Chemistry, 3100 General Physics and Astronomy, Article

File Description: application/pdf; application/application/pdf; ZORA278830.pdf - application/pdf

Access URL: https://doaj.org/article/5ed40093c17942c4ad588f09639912ce
https://serval.unil.ch/resource/serval:BIB_A8042DF76EC3.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_A8042DF76EC3
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A8042DF76EC34
http://hdl.handle.net/20.500.11850/739221
https://www.zora.uzh.ch/id/eprint/278830/
https://doi.org/10.5167/uzh-278830

Systemic Changes in Adults With a Fontan Circulation: Insights From the Plasma Proteome

Authors: Benjamin Kelly Maren Ravndal Peter Bach et al.

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 14, Iss 10 (2025)
Kelly, B, Ravndal, M, Bach, P, Telinius, N, Bennike, T B & Hjortdal, V E 2025, 'Systemic Changes in Adults With a Fontan Circulation : Insights From the Plasma Proteome', Journal of the American Heart Association, vol. 14, no. 10, e038648. https://doi.org/10.1161/JAHA.124.038648

Subject Terms: Adult, Male, hypoplastic left heart, Proteome/metabolism, Blood Proteins/metabolism, Fontan Procedure/adverse effects, Heart Defects, Congenital/surgery, Young Adult, angiogenesis, proteomics, inflammation, Case-Control Studies, RC666-701, Univentricular Heart/surgery, Humans, Diseases of the circulatory (Cardiovascular) system, Female, Proteomics/methods, Biomarkers/blood, Fontan

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40371574
https://doaj.org/article/2d338385e5ac4f32af0564ef57c3a8e6

Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes

Authors: Narainrit Karuna Claire Tonry Mark Ledwidge et al.

Source: J Transl Med
Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-15 (2025)
Karuna, N, Tonry, C, Ledwidge, M, Glezeva, N, Gallagher, J, McDonald, K & Watson, C J 2025, 'Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes', Journal of Translational Medicine, vol. 23, 546. https://doi.org/10.1186/s12967-025-06563-7

Subject Terms: Heart Failure, Proteomics, Male, Research, proteomics/methods, Middle Aged, Cohort Studies, aged, biomarkers/blood, female, natriuretic peptide, brain/blood, Early Diagnosis, male, cohort studies, middle aged, Natriuretic Peptide, Brain, Medicine, Humans, Female, humans, heart failure/diagnosis, Biomarkers, early diagnosis, Aged

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40375290
https://doaj.org/article/804a69eb60ea4be6a1328d81a6cb2570
https://pure.qub.ac.uk/en/publications/a4f5c872-9a78-4656-b499-d8bcf4fbec8a

Multi-omic approach to characterize the venom of the parasitic wasp Cotesia congregata (Hymenoptera: Braconidae)

Authors: Moreau, Sébastien Marchal, Lorène Boulain, Hélène et al.

Contributors: Moreau, Sébastien Marchal, Lorène Boulain, Hélène et al.

Source: BMC Genomics
BMC Genomics, Vol 26, Iss 1, Pp 1-20 (2025)
BMC genomics, vol. 26, no. 1, pp. 431

Subject Terms: Proteomics, Animals, Wasps/genetics, Wasps/virology, Wasps/metabolism, Wasp Venoms/genetics, Wasp Venoms/metabolism, Wasp Venoms/chemistry, Female, Proteomics/methods, Insect Proteins/genetics, Insect Proteins/metabolism, Insect Proteins/chemistry, Multiomics, Cotesia congregata, Braconidae, Parasitoid, Transcriptomics, Venom, Research, Wasps, Wasp Venoms, QH426-470, [SDV] Life Sciences [q-bio], Genetics, Insect Proteins, TP248.13-248.65, Biotechnology

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40307720
https://doaj.org/article/4f245fbd26f444df91eda8b1d8757beb
https://serval.unil.ch/resource/serval:BIB_54485415898E.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_54485415898E
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_54485415898E8
https://hal.inrae.fr/hal-05070897v1
https://doi.org/10.1186/s12864-025-11604-y

Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry

Authors: Douwe Schulte Marta Šiborová Lukas Käll et al.

Source: eLife
eLife, Vol 14 (2025)

Subject Terms: Proteomics, QH301-705.5, Science, Cryoelectron Microscopy/methods, Tandem Mass Spectrometry/methods, Antibodies, proteomics, Immunology and Inflammation, Tandem Mass Spectrometry, Sequence Analysis, Protein, antibody, Humans, Biology (General), Chromatography, Liquid, epitope, Cryoelectron Microscopy, repertoire, cryoEM, Epitope Mapping/methods, Medicine, Proteomics/methods, Protein/methods, Antibodies/chemistry, Sequence Analysis, Epitope Mapping, Chromatography, Liquid

Access URL: https://pubmed.ncbi.nlm.nih.gov/40266252
https://doaj.org/article/dacc2b379ef0412fb4311005f9cc6368