Výsledky vyhľadávania - "Proteogenomics"

Proteogenomic Reassessment Provides Novel Insight into the Life Cycle of Tetrahymenathermophila.

Autori: Gu C Yang M Zhang J a ďalší

Zdroj: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2025 Nov; Vol. 24 (11), pp. 101081. Date of Electronic Publication: 2025 Sep 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics*/methods , Life Cycle Stages*/genetics , Tetrahymena thermophila*/genetics , Tetrahymena thermophila*/metabolism , Tetrahymena thermophila*/growth & development , Protozoan Proteins*/metabolism , Protozoan Proteins*/genetics, Protein Processing, Post-Translational ; Proteome

Leveraging Proteomics and Proteogenomics for Understanding Osteoporosis and Other Musculoskeletal Diseases.

Autori: Hasebe M Su CY Kiel DP a ďalší

Zdroj: Current osteoporosis reports [Curr Osteoporos Rep] 2025 Oct 11; Vol. 23 (1), pp. 43. Date of Electronic Publication: 2025 Oct 11.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Current Science Country of Publication: United States NLM ID: 101176492 Publication Model: Electronic Cited Medium: Internet ISSN: 1544-2241 (Electronic) Linking ISSN: 15441873 NLM ISO Abbreviation: Curr Osteoporos Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoporosis*/genetics , Osteoporosis*/metabolism , Proteomics*/methods , Proteogenomics* , Sarcopenia*/genetics , Sarcopenia*/metabolism , Musculoskeletal Diseases*/genetics , Musculoskeletal Diseases*/metabolism , Osteoarthritis*/genetics , Osteoarthritis*/metabolism, Humans ; Biomarkers/metabolism ; Genome-Wide Association Study

Distant metastases of melanoma exhibit varying extent of intrapatient proteogenomic heterogeneity.

Autori: Szeitz B Hagemeijer YP Pahi ZG a ďalší

Zdroj: Clinical and translational medicine [Clin Transl Med] 2025 Oct; Vol. 15 (10), pp. e70477.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Melanoma*/genetics , Melanoma*/pathology , Proteogenomics*/methods , Neoplasm Metastasis*/genetics, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; Aged, 80 and over

Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells.

Autori: Walters K Castro-Gutierrez R Sarkar S a ďalší

Zdroj: Diabetes [Diabetes] 2025 Dec 01; Vol. 74 (12), pp. 2322-2336.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/immunology , Proteogenomics*/methods , Open Reading Frames*/genetics , Antigen Presentation*/genetics , HLA Antigens*/immunology , HLA Antigens*/genetics , HLA Antigens*/metabolism, Humans

PatientProfiler: building patient-specific signaling models from proteogenomic data.

Autori: Lombardi V Di Rocco L Meo E a ďalší

Zdroj: Molecular systems biology [Mol Syst Biol] 2025 Dec; Vol. 21 (12), pp. 1845-1865. Date of Electronic Publication: 2025 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Signal Transduction* , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Proteogenomics*/methods , Computational Biology*/methods, Humans ; Female ; Biomarkers, Tumor/genetics ; Prognosis ; Transcriptome

Integrative Proteogenomics and Forward Genetics Reveal a Novel Mitotic Vulnerability in Triple-Negative Breast Cancer.

Autori: Neill NJ Satpathy S Krug K a ďalší

Zdroj: Cancer discovery [Cancer Discov] 2025 Nov 03; Vol. 15 (11), pp. 2326-2343.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Výrazy zo slovníka MeSH: Triple Negative Breast Neoplasms*/genetics , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Mitosis*/genetics , Proteogenomics*/methods, Humans ; Female ; Cell Line, Tumor ; Animals ; Mice

The proteogenomic landscape of the human kidney and implications for cardio-kidney-metabolic health.

Autori: Hirohama D Fadista J Ha E a ďalší

Zdroj: Nature medicine [Nat Med] 2025 Nov; Vol. 31 (11), pp. 3917-3929. Date of Electronic Publication: 2025 Aug 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Kidney*/metabolism , Kidney*/pathology , Proteogenomics*/methods , Cardio-Renal Syndrome*/genetics , Cardio-Renal Syndrome*/metabolism, Humans ; Quantitative Trait Loci/genetics ; Genome-Wide Association Study ; Proteomics/methods ; Mendelian Randomization Analysis

Proteogenomic Identification of Annotated and Novel smORFs Via Microprotein Enrichment.

Autori: He C Zhang Y Xu P

Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2026; Vol. 2992, pp. 51-60.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics*/methods , Open Reading Frames*/genetics , Molecular Sequence Annotation*/methods, Saccharomyces cerevisiae/genetics ; Mass Spectrometry/methods ; Genome, Fungal

A Novel Machine Learning Post-processing Filter for Mass Spectrometry-Based Proteogenomics Leveraging Retention Time Deviation and Peptide Physicochemical Properties.

Autori: Wei F Sasada T

Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2026; Vol. 2980, pp. 251-259.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Machine Learning* , Peptides*/chemistry , Mass Spectrometry*/methods , Proteogenomics*/methods , Proteomics*/methods, Humans ; Software ; Workflow

Assessing Long-Term Stored Tissues for Multi-Omics Data Quality and Proteogenomics Suitability.

Autori: Song KJ Kim M Heo YJ a ďalší

Zdroj: Journal of proteome research [J Proteome Res] 2025 Sep 05; Vol. 24 (9), pp. 4563-4574. Date of Electronic Publication: 2025 Aug 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics*/methods , Neoplasms*/genetics , Neoplasms*/pathology , Neoplasms*/metabolism , Proteomics*/methods , Specimen Handling*, Humans ; Protein Processing, Post-Translational ; Transcriptome/genetics ; Data Accuracy ; Gene Expression Profiling ; Genomics/methods ; Phosphorylation ; Multiomics

Proteogenomic characterization unveils biomarkers associated with chemoresistance in muscle-invasive bladder cancer.

Autori: Holt MV Dou Y Young MN a ďalší

Zdroj: Cell reports. Medicine [Cell Rep Med] 2025 Aug 19; Vol. 6 (8), pp. 102255. Date of Electronic Publication: 2025 Jul 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Urinary Bladder Neoplasms*/genetics , Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/drug therapy , Urinary Bladder Neoplasms*/metabolism , Drug Resistance, Neoplasm*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Proteogenomics*/methods, Humans ; Male ; Female ; ATPases Associated with Diverse Cellular Activities/metabolism ; ATPases Associated with Diverse Cellular Activities/genetics ; Neoplasm Invasiveness ; Aged ; Middle Aged ; Signal Transduction ; Proteomics/methods ; Cell Adhesion Molecules/metabolism

The melanoma MEGA-study: Integrating proteogenomics, digital pathology, and AI-analytics for precision oncology.

Autori: Guedes J Szadai L Woldmar N a ďalší

Zdroj: Journal of proteomics [J Proteomics] 2025 Aug 15; Vol. 319, pp. 105482. Date of Electronic Publication: 2025 Jun 16.

Spôsob vydávania: Journal Article; Multicenter Study; Observational Study

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101475056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7737 (Electronic) Linking ISSN: 18743919 NLM ISO Abbreviation: J Proteomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Melanoma*/pathology , Melanoma*/genetics , Melanoma*/metabolism , Precision Medicine*/methods , Proteogenomics*/methods , Skin Neoplasms*/pathology , Skin Neoplasms*/genetics , Skin Neoplasms*/metabolism, Female ; Humans ; Male ; Machine Learning ; Tumor Microenvironment

Unraveling ADAR-Mediated Protein Recoding: A Proteogenomic Exploration in Model Organisms and Human Pathology.

Autori: Kudriavskii VV Kliuchnikova AA Goncharov AO a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 16; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 16.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Adenosine Deaminase*/metabolism , Adenosine Deaminase*/genetics , RNA Editing* , Proteogenomics*/methods , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Animals ; Humans ; Proteome/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Mice

ProHap Explorer: Visualizing Haplotypes in Proteogenomic Datasets.

Autori: Vasicek J Skiadopoulou D Kuznetsova KG a ďalší

Zdroj: IEEE computer graphics and applications [IEEE Comput Graph Appl] 2025 Sep-Oct; Vol. 45 (5), pp. 64-77.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: IEEE Computer Society Country of Publication: United States NLM ID: 9881869 Publication Model: Print Cited Medium: Internet ISSN: 1558-1756 (Electronic) Linking ISSN: 02721716 NLM ISO Abbreviation: IEEE Comput Graph Appl Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics*/methods , Haplotypes*/genetics , Computer Graphics* , Software* , Databases, Protein* , Proteome*/genetics, Humans ; User-Computer Interface

Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.

Autori: Kuliesius J Timmers PRHJ Navarro P a ďalší

Zdroj: Communications biology [Commun Biol] 2025 Aug 29; Vol. 8 (1), pp. 1300. Date of Electronic Publication: 2025 Aug 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics*/methods , Drug Discovery*/methods , Blood Proteins*/genetics, Humans ; Scotland ; Quantitative Trait Loci ; Genome-Wide Association Study ; Male ; Cohort Studies ; Diabetes Mellitus, Type 2/genetics ; Mendelian Randomization Analysis ; Glucuronosyltransferase/genetics ; Prostatic Neoplasms/genetics

Integrative proteogenomic characterization of Wilms tumor.

Autori: Cheng C Zhang L Chang X a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Aug 19; Vol. 16 (1), pp. 7715. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Wilms Tumor*/genetics , Wilms Tumor*/metabolism , Wilms Tumor*/pathology , Proteogenomics*/methods , Kidney Neoplasms*/genetics , Kidney Neoplasms*/metabolism , Kidney Neoplasms*/pathology, Humans ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Transcriptome ; Female ; Exome Sequencing ; Gene Expression Regulation, Neoplastic ; Male ; Wnt Signaling Pathway/genetics ; Prognosis ; Epigenesis, Genetic ; Tumor Microenvironment ; Kidney/pathology ; Kidney/metabolism ; Proteomics/methods ; Mutation ; Proteome/genetics ; Child

Precise Discovery of Novel N-Terminal Proteoforms beyond the Limitations of Proteogenomics and De Novo Sequencing.

Autori: He C Su K Liu H a ďalší

Zdroj: Analytical chemistry [Anal Chem] 2025 Aug 12; Vol. 97 (31), pp. 16986-16994. Date of Electronic Publication: 2025 Jul 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteogenomics* , Peptides*/chemistry , Peptides*/analysis, Humans ; Algorithms ; Sequence Analysis, Protein ; Mass Spectrometry

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy.

Autori: Huber F Arnaud M Stevenson BJ a ďalší

Zdroj: Nature biotechnology [Nat Biotechnol] 2025 Aug; Vol. 43 (8), pp. 1360-1372. Date of Electronic Publication: 2024 Oct 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antigens, Neoplasm*/immunology , Antigens, Neoplasm*/genetics , Proteogenomics*/methods , Immunotherapy*/methods , Neoplasms*/therapy , Neoplasms*/immunology , Neoplasms*/genetics , Precision Medicine*/methods, Humans ; Software ; Cancer Vaccines/immunology

Proteogenomics-enabled discovery of novel small open reading frame (sORF)-encoded polypeptides in human and mouse tissues.

Autori: Yang M Xie Y Wang L a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2025 Jul 19; Vol. 53 (14).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Open Reading Frames*/genetics , Proteogenomics*/methods , Peptides*/genetics , Peptides*/metabolism, Humans ; Animals ; Mice ; Organ Specificity

Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.

Autori: Jaehnig EJ Fernandez-Martinez A Vashist TD a ďalší

Zdroj: Cell reports. Medicine [Cell Rep Med] 2025 Jun 17; Vol. 6 (6), pp. 102154. Date of Electronic Publication: 2025 Jun 05.

Spôsob vydávania: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Drug Resistance, Neoplasm*/genetics , Proteogenomics*/methods , Receptor, ErbB-2*/metabolism , Receptor, ErbB-2*/genetics, Female ; Humans ; Epithelial-Mesenchymal Transition/drug effects ; Lapatinib/therapeutic use ; Neoadjuvant Therapy ; Trastuzumab/therapeutic use