Výsledky vyhľadávania - "Proteins chemistry"

Spotlight on cytochrome b561 and DOMON domain proteins

Autori: Joaquín Clúa Aime Jaskolowski Luciano A. Abriata a ďalší

Zdroj: Trends in plant science, vol. 30, no. 6, pp. 665-677

Predmety: Plant Proteins/metabolism, Plant Proteins/genetics, Plant Proteins/chemistry, Protein Domains, Cytochrome b Group/metabolism, Stress, Physiological, Plants/metabolism, Plants/enzymology, Plants/genetics, Oxidation-Reduction, DOMON domain, ROS signaling, abiotic stress, cytochrome b561, iron homeostasis, root development

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39674795
https://serval.unil.ch/notice/serval:BIB_3C4BAE69CCDD
https://serval.unil.ch/resource/serval:BIB_3C4BAE69CCDD.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3C4BAE69CCDD1

Stabilization of Condensate Interfaces Using Dynamic Protein Insertion

Autori: Yannick H. A. Leurs Sanne N. Giezen Yudong Li a ďalší

Zdroj: J Am Chem Soc

Predmety: SDG 3 - Good Health and Well-being, Surface Properties, Organelles/chemistry, Protein Stability, Communication, SDG 3 – Goede gezondheid en welzijn, Proteins/chemistry

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40411463
https://research.tue.nl/en/publications/00ae5073-60f9-4727-b6ae-9bc8cd781450
https://doi.org/10.1021/jacs.5c03740

Employing the SpyTag-SpyCatcher Reaction for the Modification of Supramolecular Polymers with Functional Proteins

Autori: Fenna W.B. Craenmehr Alexander Gräwe Victor A. Veenbrink a ďalší

Zdroj: Bioconjug Chem
Bioconjugate Chemistry

Predmety: Polymers/chemistry, Humans, Peptides/chemistry, Article, Proteins/chemistry

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40365870

Integrating Machine Learning-Based Pose Sampling with Established Scoring Functions for Virtual Screening

Autori: Thi Ngoc Lan Vu Hosein Fooladi Johannes Kirchmair

Zdroj: J Chem Inf Model

Predmety: Machine Learning, Molecular Docking Simulation, 106005 Bioinformatik, Preclinical/methods, Protein Conformation, 102001 Artificial intelligence, 102001 Artificial Intelligence, Drug Evaluation, 106005 Bioinformatics, 301207 Pharmazeutische Chemie, Article, 301207 Pharmaceutical chemistry, Proteins/chemistry

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40343848

Hyphenation of Affinity Capillary Electrophoresis with Mass Spectrometry for the Study of Ligand–Protein Interactions: n-Methylmorpholine Acetate Buffer and Polydopamine-Based Coating as Key Assets

Autori: Davoine, Clara Fillet, Marianne ULiège - Université de Liège a ďalší

Prispievatelia: Davoine, Clara Fillet, Marianne ULiège - Université de Liège a ďalší

Zdroj: Analytical Chemistry. 97:3988-3995

Predmety: Drug discovery, Proteins, Electrophoresis, Capillary, Pharmacie, pharmacologie & toxicologie, Morpholines/chemistry, Ligands, Biochimie, biophysique & biologie moléculaire, Life sciences, Sciences de la santé humaine, Mass Spectrometry, Analytical Chemistry, Physiological condition, Affinity capillary electrophoresis, Sciences du vivant, N-methylmorpholine, Human health sciences, polydopamine, Pharmacy, pharmacology & toxicology, Proteins/chemistry, Proteins/analysis, Protein Binding, Ligand-protein interaction, Biochemistry, biophysics & molecular biology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39933826

Home is where the lipids are: a comparison of MSP and DDDG nanodiscs for membrane protein research: A comparison of MSP and DDDG nanodiscs for membrane protein research

Autori: Kaori Nakao Alexandra Steinhauser Grégory Durand a ďalší

Zdroj: Soft Matter. 21:6596-6602

Predmety: Membrane Proteins/chemistry, Thermococcus/chemistry, Glucosides/chemistry, Nanostructures/chemistry, Lipid Bilayers/chemistry

Chemical tools for probing histidine modifications

Autori: Nurgül Bilgin Jordi C. J. Hintzen Jasmin Mecinović

Zdroj: Chemical Communications. 61:3805-3820

Predmety: Post-Translational, Histidine/chemistry, Humans, Peptides/chemistry, Methylation, Protein Processing, Proteins/chemistry

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39936705
https://portal.findresearcher.sdu.dk/da/publications/136604a7-4d91-43d3-a9e7-81a525900ad4
https://doi.org/10.1039/d4cc06586g

Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation

Autori: Kasper Holst Hansen Mert Golcuk Chang Hyeock Byeon a ďalší

Zdroj: Hansen, K H, Golcuk, M, Byeon, C H, Tunc, A, Plechinger, E B, Dueholm, M K D, Conway, J F, Andreasen, M, Gur, M & Akbey, Ü 2025, 'Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation', Science Advances, vol. 11, no. 39, eadx7829, pp. eadx7829. https://doi.org/10.1126/sciadv.adx7829

Predmety: Amyloid/chemistry, Pseudomonas aeruginosa/physiology, Bacterial Proteins/chemistry, Protein Conformation, Cryoelectron Microscopy, Pseudomonas/physiology, Biofilms/growth & development, Molecular Dynamics Simulation

Popis súboru: application/pdf

Prístupová URL adresa: https://vbn.aau.dk/da/publications/d37e8648-1897-40ac-aef1-bbcb8376ce08
https://vbn.aau.dk/ws/files/797890299/sciadv.adx7829.pdf
https://doi.org/10.1126/sciadv.adx7829

Cryo-EM structures of the MnmE–MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification

Autori: Laila Maes Israel Mares-Mejía Ella Martin a ďalší

Prispievatelia: Laila Maes Israel Mares-Mejía Ella Martin a ďalší

Zdroj: Nucleic Acids Research. 53

Predmety: Models, Molecular, RNA, Transfer/metabolism, Methyltransferases/chemistry, Protein Conformation, Flavin-Adenine Dinucleotide/metabolism, Escherichia coli Proteins/chemistry, Cryoelectron Microscopy, NAD/metabolism, Protein Binding, GTP Phosphohydrolases

Prístupová URL adresa: https://biblio.vub.ac.be/vubir/cryoem-structures-of-the-mnmemnmg-complex-reveal-large-conformational-changes-and-provide-new-insights-into-the-mechanism-of-trna-modification(e0a1d23a-e82f-4641-8e99-f03cd8c1729f).html

Specificity in clustering of gene-specific transcription factors is encoded in the genome

Autori: Shivali Dongre Nadine L Vastenhouw

Zdroj: Nucleic Acids Res
Nucleic acids research, vol. 53, no. 13

Predmety: Gene regulation, Chromatin and Epigenetics, Animals, Zebrafish/genetics, Zebrafish/embryology, Zebrafish/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Transcription Factors/chemistry, Zebrafish Proteins/genetics, Zebrafish Proteins/metabolism, Zebrafish Proteins/chemistry, Genome, Multigene Family, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism, Octamer Transcription Factor-3/chemistry, Nanog Homeobox Protein/genetics, Nanog Homeobox Protein/metabolism, Intrinsically Disordered Proteins/metabolism, Intrinsically Disordered Proteins/genetics, DNA/metabolism, Embryo, Nonmammalian/metabolism

Popis súboru: application/pdf

Prístupová URL adresa: https://serval.unil.ch/notice/serval:BIB_4CD68E481E64
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4CD68E481E641
https://serval.unil.ch/resource/serval:BIB_4CD68E481E64.P001/REF.pdf

Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein

Autori: Sobek, Jens Li, Junhao Combes, Benjamin Francois a ďalší

Prispievatelia: Sobek, Jens Li, Junhao Combes, Benjamin Francois a ďalší

Zdroj: Eur J Nucl Med Mol Imaging
Sobek, Jens; Li, Junhao; Combes, Benjamin F; Gerez, Juan A; Henrich, Martin T; Geibl, Fanni F; Nilsson, Peter R; Shi, Kuangyu; Rominger, Axel; Oertel, Wolfgang H; Nitsch, Roger M; Nordberg, Agneta; Ågren, Hans; Ni, Ruiqing (2024). Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein. (In Press). European journal of nuclear medicine and molecular imaging Springer 10.1007/s00259-024-06806-7 <http://dx.doi.org/10.1007/s00259-024-06806-7>
Sobek, Jens; Li, Junhao; Combes, Benjamin F; Gerez, Juan A; Henrich, Martin T; Geibl, Fanni F; Nilsson, Peter R; Shi, Kuangyu; Rominger, Axel; Oertel, Wolfgang H; Nitsch, Roger M; Nordberg, Agneta; Ågren, Hans; Ni, Ruiqing (2024). Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein. European journal of nuclear medicine and molecular imaging, 51(13), pp. 3960-3977. Springer 10.1007/s00259-024-06806-7 <http://dx.doi.org/10.1007/s00259-024-06806-7>
European Journal of Nuclear Medicine and Molecular Imaging, 51 (13)

Predmety: Male, Amyloid, Binding sites, 610 Medicine & health, tau Proteins, Biochemistry, Fluorescence, 170 Ethics, Alpha-synuclein, Mice, Amyloid beta-Protein Precursor, Forensic Imaging, synuclein, Surface plasmon resonance, Humans, Animals, 10237 Institute of Biomedical Engineering, Computer Simulation, Biokemi, Molecular Biology, Aged, Brain Chemistry, Alpha, Molekylärbiologi, Binding Sites, In silico, Brain, Läkemedelskemi, 11359 Institute for Regenerative Medicine (IREM), Middle Aged, Surface Plasmon Resonance, Recombinant Proteins, Protein Structure, Tertiary, 3. Good health, Mice, Inbred C57BL, Amyloid beta-Protein Precursor/chemistry [MeSH], Surface Plasmon Resonance [MeSH], Mice, Inbred C57BL [MeSH], Aged [MeSH], Amyloid-beta, Protein Structure, Tertiary [MeSH], Computer Simulation [MeSH], Brain Chemistry [MeSH], Forensic Imaging [MeSH], Original Article, Male [MeSH], alpha-Synuclein/chemistry [MeSH], Fluorescence [MeSH], Amyloid beta-Protein Precursor/metabolism [MeSH], tau Proteins/chemistry [MeSH], Humans [MeSH], Middle Aged [MeSH], Animals [MeSH], Mice [MeSH], Binding Sites [MeSH], Brain/metabolism [MeSH], Tau, Recombinant Proteins/chemistry [MeSH], alpha-Synuclein/metabolism [MeSH], tau Proteins/metabolism [MeSH], Recombinant Proteins/metabolism [MeSH], alpha-Synuclein, beta, Medicinal Chemistry

Popis súboru: application/pdf; application/application/pdf; ZORA_260747.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38953933
https://boris.unibe.ch/198396/
https://repository.publisso.de/resource/frl:6508032
http://hdl.handle.net/20.500.11850/682590
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-206432
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-548381
https://www.zora.uzh.ch/id/eprint/260747/
https://doi.org/10.5167/uzh-260747

Gold Nanoparticles Decorated with HPLC6-Derived Peptides as a Platform for Ice Recrystallization Inhibition

Autori: Impresari, Elisa Peqini, Kaliroi Hogervorst, Tim P. a ďalší

Zdroj: Biomacromolecules. 26:715-725

Predmety: Antifreeze Proteins/chemistry, Gold/chemistry, Ice, Metal Nanoparticles/chemistry, Humans, Crystallization, Peptides/chemistry

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39688229
https://research.tue.nl/en/publications/1f53b115-b6ce-40c9-8f3e-39ea0fc5bbf7
https://doi.org/10.1021/acs.biomac.4c01586
https://hdl.handle.net/2434/1125695
https://doi.org/10.1021/acs.biomac.4c01586

Molecular basis for thiocarboxylation and release of Urm1 by its E1-activating enzyme Uba4

Autori: Sokołowski, Mikołaj Kwasna, Dominika Ravichandran, Keerthiraju E a ďalší

Zdroj: Nucleic Acids Res

Predmety: Models, Molecular, 0301 basic medicine, Saccharomyces cerevisiae Proteins, Saccharomyces cerevisiae Proteins Genetics, Saccharomyces cerevisiae Proteins Metabolism, Ubiquitin-Activating Enzymes, Saccharomyces cerevisiae, Saccharomyces Cerevisiae Genetics, RNA, Transfer Chemistry, Ubiquitin-Activating Enzymes Genetics, 03 medical and health sciences, Sulfhydryl Compounds Metabolism, Protein Domains, RNA, Transfer, RNA, Transfer Metabolism, Saccharomyces cerevisiae Metabolism, Sulfhydryl Compounds, Nucleotidyltransferases Chemistry, Ubiquitins, Ubiquitin-Activating Enzymes Chemistry, 0303 health sciences, Nucleotidyltransferases Metabolism, Ubiquitin-Activating Enzymes Metabolism, Ubiquitins Genetics, Cryoelectron Microscopy, Ubiquitins Metabolism, Molecular and Structural Biology, Nucleotidyltransferases, Ubiquitins Chemistry, Sulfhydryl Compounds Chemistry, Mutation, Nucleotidyltransferases Genetics, Saccharomyces cerevisiae Proteins Chemistry, Protein Binding

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39673271
https://ruj.uj.edu.pl/handle/item/499751
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1111/7914207

Molecular basis of plastoquinone reduction in plant cytochrome b6f

Autori: Pintscher, Sebastian Pietras, Rafał Mielecki, Bohun a ďalší

Zdroj: Nat Plants

Predmety: Models, Molecular, Plant Proteins Genetics, Plastoquinone, Models Molecular, Cryoelectron Microscopy, Cytochrome b6f Complex Metabolism, Spinacia oleracea Metabolism, Article, Plastoquinone Metabolism, Cytochrome b6f Complex, Spinacia oleracea, Cytochrome b6f Complex Chemistry, Plant Proteins Metabolism, Plant Proteins Chemistry, Oxidation-Reduction, Plant Proteins

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39362993
https://www.nature.com/articles/s41477-024-01804-x
https://ruj.uj.edu.pl/handle/item/460222
https://phaidra.vetmeduni.ac.at/o:3764
https://doi.org/10.1038/s41477-024-01804-x

The Comprehensive Guide to the Egyptian False Cobra

Autori: dimatri, mina

Predmety: Cobra Cardiotoxin Proteins/poisoning, Snake Venoms/biosynthesis, Reptiles/urine, Cobra Cardiotoxin Proteins, Snake Bites, Snake Venoms/pharmacokinetics, Snake Venoms/metabolism, Cobra Neurotoxin Proteins/chemistry, Cobra, Cobra Neurotoxin Proteins/pharmacokinetics, Cobra Neurotoxin Proteins/pharmacology, Reptiles/genetics, Cobra Cardiotoxin Proteins/genetics, Cobra Cardiotoxin Proteins/immunology, Snake Venoms/chemistry, Reptiles/growth & development, Reptiles/virology, Snakes, Snake Bites/mortality, Snake Bites/virology, Reptiles/surgery, Reptiles/anatomy & histology, Cobra Neurotoxin Proteins/immunology, Cobra Neurotoxin Proteins/urine, Snake Bites/parasitology, Reptiles/embryology, Cobra Neurotoxin Proteins/agonists, Cobra Cardiotoxin Proteins/pharmacology, Snake Venoms/urine, Reptiles/microbiology, Snake Venoms, Cobra Neurotoxin Proteins/metabolism, Snake Bites/veterinary, Snake, Cobra Cardiotoxin Proteins/urine, Reptile, Cobra Cardiotoxin Proteins/history, Reptiles/metabolism, Snake Venoms/history, Reptiles/classification, Snake Venoms/immunology, Snake Venoms/analysis, Reptiles/injuries, Reptiles/abnormalities, Cobra Neurotoxin Proteins, Snake Venoms/agonists, Cobra Cardiotoxin Proteins/agonists, Reptiles, Reptiles/blood, Reptiles/cerebrospinal fluid, Snake Bites/ethnology, Cobra Neurotoxin Proteins/blood, Reptiles/physiology, Cobra Neurotoxin Proteins/poisoning, Snake Venoms/blood, Snake Bites/embryology, Egyptian false cobra, Reptiles/immunology, Reptiles/parasitology, Cobra Neurotoxin Proteins/classification, Peptides

Rapid interpretation of protein backbone rotation dynamics directly from spin relaxation data

Autori: Ollila Samuli Mantzari Efstathia Sandelin Amanda E. a ďalší

Prispievatelia: Ollila Samuli Mantzari Efstathia Sandelin Amanda E. a ďalší

Zdroj: J Phys Chem Lett

Predmety: Intrinsically Disordered Proteins, Intrinsically Disordered Proteins/chemistry, Chemical sciences, Rotation, Protein Conformation, Nuclear Magnetic Resonance, Proteins, Peptides/chemistry, Peptides, Nuclear Magnetic Resonance, Biomolecular, Micelles, Biomolecular, Proteins/chemistry

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39353179
https://cris.vtt.fi/en/publications/0034f588-c523-422b-8297-2e997c7dca30
https://doi.org/10.1021/acs.jpclett.4c01800
http://hdl.handle.net/10138/587141

FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions

Autori: Pablo Alcón Artur P. Kaczmarczyk Korak Kumar Ray a ďalší

Prispievatelia: Pablo Alcón Artur P. Kaczmarczyk Korak Kumar Ray a ďalší

Zdroj: Nature

Predmety: Cell Extracts, DNA Replication, Models, Molecular, DNA Repair, DNA, Single-Stranded, Article, Diffusion, Xenopus laevis, Models, Animals, Humans, Fanconi Anemia Complementation Group D2 Protein/chemistry, General, DNA/chemistry, Fanconi Anemia Complementation Group D2 Protein, Cryoelectron Microscopy, Molecular, DNA, Fanconi Anemia Complementation Group Proteins, Single Molecule Imaging, 3. Good health, Fanconi Anemia Complementation Group Proteins/chemistry, Single-Stranded/chemistry, Female, DNA Damage, Protein Binding

Popis súboru: application/pdf; text/xml; application/zip

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39085614
https://hdl.handle.net/20.500.11755/bf79e9ad-8007-4d72-9eb6-f2dcd1647d60
https://pure.knaw.nl/portal/en/publications/bf79e9ad-8007-4d72-9eb6-f2dcd1647d60
https://doi.org/10.1038/s41586-024-07770-w
https://dspace.library.uu.nl/handle/1874/455837
https://www.repository.cam.ac.uk/handle/1810/373061
https://doi.org/10.1038/s41586-024-07770-w
https://www.repository.cam.ac.uk/handle/1810/380380
https://doi.org/10.1038/s41586-024-07770-w

In Situ Measurement of Nanoparticle–Blood Protein Adsorption and Its Heterogeneity with Single-Nanoparticle Resolution via Dual Fluorescence Quantification

Autori: Yuanyuan Niu Yingjie Yu Xinyang Shi a ďalší

Zdroj: Nano Lett
Nano Letters

Predmety: Kinetics, Kinetics [MeSH], Letter, Fluorescence [MeSH], nanomedicine, Nanoparticles/chemistry [MeSH], protein corona, Humans [MeSH], drug delivery, Blood Proteins/analysis [MeSH], nano-bio interaction, Blood Proteins/chemistry [MeSH], Protein Corona/chemistry [MeSH], Vroman effect, Adsorption [MeSH], Nanoparticles, Humans, Protein Corona, Adsorption, Blood Proteins, Fluorescence

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39037031
http://hdl.handle.net/21.11116/0000-000F-B39A-9
http://hdl.handle.net/21.11116/0000-000F-A249-8
https://repository.publisso.de/resource/frl:6488376

DNA supercoiling enhances DNA condensation by ParB proteins

Autori: Alejandro Martin Gonzalez Miloš Tišma Brian T. Analikwu a ďalší

Zdroj: Nucleic Acids Res
Nucleic acids research, vol. 52, no. 21, pp. 13255-13268
Nucleic Acids Research

Predmety: DNA, Bacterial, DNA-Binding Proteins, Bacterial Proteins, DNA, Superhelical, DNA, Superhelical/metabolism, DNA, Superhelical/chemistry, DNA, Bacterial/metabolism, Bacterial Proteins/metabolism, Bacterial Proteins/chemistry, DNA-Binding Proteins/metabolism, Chromosomes, Bacterial/metabolism, Chromosomes, Bacterial/chemistry, Escherichia coli/genetics, Escherichia coli/metabolism, Single Molecule Imaging, Escherichia coli Proteins/metabolism, Chromosome Segregation, Escherichia coli Proteins, Escherichia coli, Molecular and Structural Biology, Chromosomes, Bacterial

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39441069
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9F0306AB2E806
https://serval.unil.ch/notice/serval:BIB_9F0306AB2E80
https://serval.unil.ch/resource/serval:BIB_9F0306AB2E80.P001/REF.pdf

Sensoproteomic Characterization of Lactobacillus Johnsonii-Fermented Pea Protein-Based Beverage: A Promising Strategy for Enhancing Umami and Kokumi Sensations while Mitigating Bitterness

Autori: Andrea Spaccasassi Lijuan Ye Cristian Rincón a ďalší

Zdroj: J Agric Food Chem

Predmety: Proteomics, Adult, Male, Article, Chemistry andBiology of Aroma and Taste, Fermentation of pea protein, L. johnsonii, taste improvement, kokumi and umami, senso(prote)omics, Proteomics [MeSH], Pea Proteins/metabolism [MeSH], Lactobacillus/genetics [MeSH], Lactobacillus/metabolism [MeSH], Beverages/microbiology [MeSH], Pea Proteins/chemistry [MeSH], Male [MeSH], Flavoring Agents/chemistry [MeSH], Flavoring Agents/metabolism [MeSH], Female [MeSH], Fermentation [MeSH], Adult [MeSH], Humans [MeSH], Pisum sativum/metabolism [MeSH], Taste [MeSH], Beverages/analysis [MeSH], Pisum sativum/chemistry [MeSH], Young Adult [MeSH], Chemistry and Biology of Aroma and Taste, ddc, Flavoring Agents, Beverages, Lactobacillus, Young Adult, Taste, Fermentation, Humans, Female, Pisum sativum, Pea Proteins

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38957928
https://repository.publisso.de/resource/frl:6487067
https://mediatum.ub.tum.de/doc/1750552/document.pdf