Search Results - "Prenatal Exposure Delayed Effects chemically induced"
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1
Authors: et al.
Source: Bluett-Duncan, M, Adams, J, Berkovitch, M, Berlin, M, Cahoon, A, Clayton-Smith, J, Khanom, S, Mølgaard-Nielsen, D, Richardson, J L, Simms, V, Stellfeld, M, Winterfeld, U & Bromley, R L 2025, 'A Scoping Review of Human Teratogens and Their Impact on the Developing Brain : A Contribution From the ConcePTION Project', Birth Defects Research, vol. 117, no. 9, pp. e2497. https://doi.org/10.1002/bdr2.2497
Subject Terms: Teratogens/toxicity, Adult, Brain/drug effects, Adolescent, Pregnancy, Neurodevelopmental Disorders/chemically induced, Prenatal Exposure Delayed Effects/chemically induced, Humans, Abnormalities, Drug-Induced, Female, Child
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2
Authors: et al.
Source: Obstetrics and Gynecology, 145, 2, pp. 168-176
Subject Terms: EXPOSURES, Autism Spectrum Disorder, Prenatal Exposure Delayed Effects/chemically induced, PRENATAL USE, Non-Narcotic/adverse effects, Attention Deficit Disorder with Hyperactivity/drug therapy, Autism Spectrum Disorder/chemically induced, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, CHILD IQ, IQ health - Radboud University Medical Center, DRUGS, Humans, COHORT, Child, Obstetrics & Reproductive Medicine, Acetaminophen, RISK, Analgesics, Science & Technology, HERITABILITY, 3215 Reproductive medicine, Obstetrics & Gynecology, Analgesics, Non-Narcotic, Attention Deficit Disorder with Hyperactivity, Prenatal Exposure Delayed Effects, 1114 Paediatrics and Reproductive Medicine, Female, Life Sciences & Biomedicine, CHRONIC PAIN, Acetaminophen/adverse effects
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3
Authors: et al.
Source: Andrology. 13:259-267
Subject Terms: Male, Adult, 0301 basic medicine, pharmacoepidemiology, Prenatal Exposure Delayed Effects/chemically induced, birth outcomes, Infant, Newborn, Selective Serotonin Reuptake Inhibitors/adverse effects, Denmark/epidemiology, 3. Good health, Cohort Studies, paternal exposure, Congenital Abnormalities/epidemiology, Fathers, 03 medical and health sciences, Premature Birth/epidemiology, 0302 clinical medicine, selective serotonin reuptake inhibitors, Pregnancy, SSRIs, Paternal Exposure/adverse effects, Humans, Small for Gestational Age, Female
Access URL: https://pubmed.ncbi.nlm.nih.gov/38639021
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4
Authors: et al.
Contributors: et al.
Source: Birth Defects Research. 117
Subject Terms: Male, Adult, [SDV]Life Sciences [q-bio], Prenatal Exposure Delayed Effects/chemically induced, medications, Pregnancy, Risk Factors, Humans, Eye Abnormalities, Registries, First, Maternal Exposure/adverse effects, congenital ocular anomaly, in utero exposure, pharmacology, pregnancy, [SDV] Life Sciences [q-bio], Europe, Analgesics, Opioid, Eye Abnormalities/chemically induced, Drug-Induced/epidemiology, Maternal Exposure, Case-Control Studies, Prenatal Exposure Delayed Effects, Female, Pregnancy Trimester, Abnormalities
File Description: application/pdf
Access URL: https://pubmed.ncbi.nlm.nih.gov/39890450
https://hdl.handle.net/11370/f13939b0-c776-4518-8ca7-52f46b801c01
https://research.rug.nl/en/publications/f13939b0-c776-4518-8ca7-52f46b801c01
https://doi.org/10.1002/bdr2.2435
https://cronfa.swan.ac.uk/Record/cronfa68873
https://hal.science/hal-04928756v1
https://doi.org/10.1002/bdr2.2435
https://portal.findresearcher.sdu.dk/da/publications/92dab1e9-bc57-456b-a458-c92f179c1f4c
https://doi.org/10.1002/bdr2.2435
https://hdl.handle.net/11392/2580850
https://onlinelibrary.wiley.com/doi/10.1002/bdr2.2435
https://doi.org/10.1002/bdr2.2435 -
5
Authors: et al.
Source: Vestergaard, T, Holm Meiltoft, I, Julsgaard, M, Helmig, R B, Friedman, S & Kelsen, J 2024, 'Preterm Birth and in Utero Exposure to Corticosteroids Are Associated With Increased Infection Risk in Children of Mothers With IBD', Inflammatory Bowel Diseases, vol. 30, no. 12, izad316, pp. 2297-2305. https://doi.org/10.1093/ibd/izad316
Vestergaard, T, Holm Meiltoft, I, Julsgaard, M, Bek Helmig, R, Friedman, S & Kelsen, J 2024, 'Preterm Birth and in Utero Exposure to Corticosteroids Are Associated With Increased Infection Risk in Children of Mothers With IBD', Inflammatory Bowel Diseases, vol. 30, no. 12, pp. 2297-2305. https://doi.org/10.1093/ibd/izad316Subject Terms: Adult, Male, 0301 basic medicine, Pregnancy Complications/drug therapy, Adrenal Cortex Hormones/adverse effects, Denmark, Prenatal Exposure Delayed Effects/chemically induced, IBD, Infections, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Adrenal Cortex Hormones, Risk Factors, Inflammatory Bowel Diseases/drug therapy, Humans, biologics, Retrospective Studies, Infant, Newborn, Infant, Infections/chemically induced, infections in children, Inflammatory Bowel Diseases, Denmark/epidemiology, 3. Good health, Pregnancy Complications, Premature Birth/epidemiology, Prenatal Exposure Delayed Effects, Premature Birth, Female, pregnancy
Access URL: https://pubmed.ncbi.nlm.nih.gov/38206331
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6
Authors: et al.
Source: Reproductive Toxicology, 132, 108854 (2025-03)
Subject Terms: Bisphenol S, DNA methylation, Placenta, Steroid receptor coactivator 2, Transcription, Phenols, Sulfones, Bisphenol S Compounds, Animals, Female, Pregnancy, Male, Prenatal Exposure Delayed Effects/chemically induced, DNA Methylation/drug effects, Rats, Sprague-Dawley, Wistar, Phenols/toxicity, Placenta/drug effects, Placenta/metabolism, Sulfones/toxicity, Transcriptome/drug effects, Toxicology, Human health sciences, Pharmacy, pharmacology & toxicology, Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie
Relation: https://api.elsevier.com/content/article/PII:S0890623825000255?httpAccept=text/xml; urn:issn:0890-6238; urn:issn:1873-1708; https://orbi.uliege.be/handle/2268/329782; info:hdl:2268/329782; info:pmid:39933604
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7
Authors: et al.
Contributors: et al.
Source: Part Fibre Toxicol
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-12 (2024)Subject Terms: Male, DISORDERS, Early-life exposure, Anxiety, Female [MeSH], Mice, Inbred C57BL [MeSH], Nanoparticles/toxicity [MeSH], Anxiety/chemically induced [MeSH], Air Pollutants/toxicity [MeSH], Animals [MeSH], Maternal Exposure/adverse effects [MeSH], Mice [MeSH], Male [MeSH], Ultrafine particulate matter, Research, Anxiety-like behaviour, Prenatal Exposure Delayed Effects/chemically induced [MeSH], Particle Size [MeSH], Particulate Matter/toxicity [MeSH], Carbon/toxicity [MeSH], Behavioural development, Inhalation Exposure/adverse effects [MeSH], Behavior, Animal/drug effects [MeSH], Pregnancy [MeSH], Mice, PARTICULATE MATTER, Pregnancy, RA1190-1270, ANXIETY, Animals, COHORT, OXIDATIVE STRESS, Particle Size, RISK, Inhalation Exposure, Air Pollutants, AIR-POLLUTION EXPOSURE, Behavior, Animal, HD7260-7780.8, Carbon, Mice, Inbred C57BL, Maternal Exposure, Prenatal Exposure Delayed Effects, Toxicology. Poisons, Nanoparticles, Industrial hygiene. Industrial welfare, Female, Particulate Matter, BEHAVIOR
File Description: application/pdf
Access URL: https://pubmed.ncbi.nlm.nih.gov/39633442
https://doaj.org/article/2bd6d2175c5f4a61b7f9bbf84a1754c9
https://research-portal.uu.nl/en/publications/d6197aed-242f-4acd-9007-e9bf6a10a307
https://doi.org/10.1186/s12989-024-00612-7
https://repository.publisso.de/resource/frl:6491196
http://hdl.handle.net/1942/46258 -
8
Authors: et al.
Source: Nat Commun
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Nature Communications
Madley-Dowd, P, Ahlqvist, V H, Forbes, H, Rast, J E, Martin, F Z, Zhong, C, Barry, C-J S, Berglind, D, Lundberg, M, Lyall, K, Newschaffer, C J, Tomson, T, Davies, N M, Magnusson, C, Rai, D & Lee, B K 2024, 'Antiseizure medication use during pregnancy and children's neurodevelopmental outcomes', Nature Communications, vol. 15, no. 1, 9640. https://doi.org/10.1038/s41467-024-53813-1Subject Terms: Valproic Acid/adverse effects, Topiramate/adverse effects, Male, Adult, Pregnancy Complications/drug therapy, Adolescent, Neurodevelopmental Disorders/chemically induced, Science, Prenatal Exposure Delayed Effects/chemically induced, Carbamazepine/adverse effects, Attention Deficit Disorder with Hyperactivity/drug therapy, Lamotrigine, Article, Cohort Studies, Pregnancy, Topiramate, Intellectual Disability, Humans, Intellectual Disability/epidemiology, Registries, Autistic Disorder, Child, Sweden, Anticonvulsants/adverse effects, United Kingdom/epidemiology, Valproic Acid, Infant, United Kingdom, Pregnancy Complications, Sweden/epidemiology, Carbamazepine, Attention Deficit Disorder with Hyperactivity, Prenatal Exposure Delayed Effects, Child, Preschool, Female, Anticonvulsants, Lamotrigine/adverse effects, Autistic Disorder/drug therapy, Epilepsy/drug therapy
File Description: application/pdf
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9
Authors: et al.
Subject Terms: California: epidemiology, Case-Control Studies, Child, Child, Preschool, Environmental Exposure: adverse effects, Female, Humans, Pesticides: adverse effects, Pregnancy, Prenatal Exposure Delayed Effects: chemically induced, epidemiology, Retinal Neoplasms: chemically induced, epidemiology, Retinoblastoma: chemically induced, epidemiology
Access URL: https://escholarship.org/uc/item/3ng1j38k
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10
Authors: et al.
Source: Curr Environ Health Rep
Clemmensen, P J, Schullehner, J, Brix, N, Sigsgaard, T, Stayner, L T, Kolstad, H A & Ramlau-Hansen, C H 2023, 'Prenatal Exposure to Nitrate in Drinking Water and Adverse Health Outcomes in the Offspring : a Review of Current Epidemiological Research', Current Environmental Health Reports, vol. 10, no. 3, pp. 250-263. https://doi.org/10.1007/s40572-023-00404-9
Current Environmental Health ReportsSubject Terms: Adult, Nitrates, Drinking Water/adverse effects, Drinking Water, Prenatal Exposure Delayed Effects/chemically induced, Infant, Newborn, Nitrates/adverse effects, Nitrate, 6. Clean water, Article, 3. Good health, Young Adult, Epidemiologic Studies, Pregnancy, Prenatal Exposure Delayed Effects, Outcome Assessment, Health Care, Drinking water, Prenatal, Humans, Female
File Description: application/pdf
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11
Authors: et al.
Source: Drug Saf
Drug Safety
Dudukina, E, Szépligeti, S K, Karlsson, P, Asomaning, K, Daltveit, A K, Hakkarainen, K, Hoti, F, Kieler, H, Lunde, A, Odsbu, I, Rantanen, M, Reutfors, J, Saarelainen, L, Ehrenstein, V & Toft, G 2023, 'Prenatal exposure to pregabalin, birth outcomes and neurodevelopment – a population-based cohort study in four Nordic countries', Drug Safety, vol. 46, no. 7, pp. 661-675. https://doi.org/10.1007/s40264-023-01307-2Subject Terms: Anticonvulsants/adverse effects, Stillbirth/epidemiology, Prenatal Exposure Delayed Effects/chemically induced, Infant, Newborn, Pregabalin, Stillbirth, Scandinavian and Nordic Countries, 3. Good health, Scandinavian and Nordic Countries/epidemiology, Cohort Studies, Pregnancy, Prenatal Exposure Delayed Effects, Intellectual Disability, Pregabalin/adverse effects, Humans, Premature Birth, Female, Anticonvulsants, Original Research Article
File Description: application/pdf
Access URL: https://pubmed.ncbi.nlm.nih.gov/37099261
https://hdl.handle.net/11250/3068340
https://pure.au.dk/ws/files/384322831/Prenatal_Exposure_To_Pregabalin_Birth_Outcomes_and_Neurodevelopment_-_A_Population-Based_Cohort_Study_In_Four_Nordic_Countries.pdf
https://hdl.handle.net/11250/3068791
https://pure.au.dk/ws/files/384322831/Prenatal_Exposure_To_Pregabalin_Birth_Outcomes_and_Neurodevelopment_-_A_Population-Based_Cohort_Study_In_Four_Nordic_Countries.pdf
https://doi.org/10.1007/s40264-023-01307-2
https://pure.au.dk/portal/en/publications/220383d2-aaa8-4f98-b983-ac4d1fc0a00f
http://www.scopus.com/inward/record.url?scp=85153612756&partnerID=8YFLogxK -
12
Authors: et al.
Source: Bang Madsen, K, Robakis, T K, Liu, X, Momen, N, Larsson, H, Dreier, J W, Kildegaard, H, Groth, J B, Newcorn, J H, Hove Thomsen, P, Munk-Olsen, T & Bergink, V 2023, 'In utero exposure to ADHD medication and long-term offspring outcomes', Molecular Psychiatry, vol. 28, no. 4, pp. 1739-1746. https://doi.org/10.1038/s41380-023-01992-6
Subject Terms: Adult, Amphetamines/adverse effects, Neurodevelopmental Disorders/chemically induced, Methylphenidate/adverse effects, Denmark, Prenatal Exposure Delayed Effects/chemically induced, Mothers, Gestational Age, Modafinil, Attention Deficit Disorder with Hyperactivity/drug therapy, Clonidine, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Pregnancy, Modafinil/adverse effects, Humans, Registries, Child, Preschool, Clonidine/adverse effects, Amphetamines, Infant, SDG 10 - Reduced Inequalities, Denmark/epidemiology, Mothers/psychology, 3. Good health, Attention Deficit Disorder with Hyperactivity, Neurodevelopmental Disorders, Child, Preschool, Prenatal Exposure Delayed Effects, Methylphenidate, Female
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13
Authors: et al.
Contributors: et al.
Source: Trends in Immunology. 43:230-244
Subject Terms: Inflammation, 0301 basic medicine, 0303 health sciences, Prenatal Exposure Delayed Effects* / chemically induced, Animal, Microbiota, Inflammation / immunology, Prenatal Exposure Delayed Effects* / immunology, 3. Good health, Disease Models, Animal, 03 medical and health sciences, Pregnancy, Immune System, Prenatal Exposure Delayed Effects, Disease Models, Animals, Humans, Female
File Description: application/pdf
Access URL: https://pubmed.ncbi.nlm.nih.gov/35131181
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14
Authors: et al.
Source: Momen, N C, Robakis, T, Liu, X, Reichenberg, A, Bergink, V & Munk-Olsen, T 2022, 'In utero exposure to antipsychotic medication and psychiatric outcomes in the offspring', Neuropsychopharmacology, vol. 47, no. 3, pp. 759-766. https://doi.org/10.1038/s41386-021-01223-y
NeuropsychopharmacologySubject Terms: Mental Disorders, Prenatal Exposure Delayed Effects/chemically induced, 3. Good health, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Pregnancy, Prenatal Exposure Delayed Effects, Humans, Mental Disorders/diagnosis, Female, Antipsychotic Agents/adverse effects, Child, Antipsychotic Agents, Proportional Hazards Models
Access URL: https://pubmed.ncbi.nlm.nih.gov/34750566
https://pure.eur.nl/en/publications/b54db0ee-ed05-46ff-8ac0-1b9a9e699c2e
https://doi.org/10.1038/s41386-021-01223-y
https://www.nature.com/articles/s41386-021-01223-y.pdf
https://www.nature.com/articles/s41386-021-01223-y
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782838/pdf/41386_2021_Article_1223.pdf
http://www.scopus.com/inward/record.url?scp=85118611778&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/ba07f198-cf7a-48b3-96dc-6cc2e67b82e9
https://doi.org/10.1038/s41386-021-01223-y -
15
Authors: et al.
Source: Environ Health
Environmental Health, Vol 22, Iss 1, Pp 1-11 (2023)
Beck, I H, Bilenberg, N, Andersen, H R, Trecca, F, Bleses, D & Jensen, T K 2023, 'Association between prenatal or early postnatal exposure to perfluoroalkyl substances and language development in 18 to 36-month-old children from the Odense Child Cohort', Environmental Health: A Global Access Science Source, vol. 22, 46. https://doi.org/10.1186/s12940-023-00993-wSubject Terms: Fluorocarbons/adverse effects, Prenatal Exposure Delayed Effects/chemically induced, PFAS, Neurodevelopment, MacArthur-Bates Communicative Development inventories, Language Development, Pregnancy, Environmental Pollutants/adverse effects, Animals, Humans, Prospective Studies, Language development, Preschool, Child, First, Fluorocarbons, Research, Infant, Brain, MB-CDI, Industrial medicine. Industrial hygiene, 3. Good health, RC963-969, Pregnancy Trimester, First, Perfluoroalkyl substances, Alkanesulfonic Acids, Child, Preschool, Prenatal Exposure Delayed Effects, Female, Environmental Pollutants, Pregnancy Trimester, The Odense Child Cohort, Public aspects of medicine, RA1-1270
Access URL: https://pubmed.ncbi.nlm.nih.gov/37254153
https://doaj.org/article/fd64488517344b729c73921d95c4d912
http://www.scopus.com/inward/record.url?scp=85160607274&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/43408b5b-7530-4fb0-91eb-b4e02957b7e7
https://doi.org/10.1186/s12940-023-00993-w -
16
Authors: et al.
Source: American journal of epidemiology, vol 190, iss 6
Inoue, K, Ritz, B, Ernst, A, Tseng, W-L, Yuan, Y, Meng, Q, Ramlau-Hansen, C H, Strandberg-Larsen, K, Arah, O A, Obel, C, Li, J, Olsen, J & Liew, Z 2021, 'Behavioral Problems at Age 11 Years After Prenatal and Postnatal Exposure To Acetaminophen : Parent-reported and Self-reported Outcomes', American Journal of Epidemiology, vol. 190, no. 6, pp. 1009-1020. https://doi.org/10.1093/aje/kwaa257Subject Terms: Parents, multiple informants' comparison, paracetamol, Epidemiology, Denmark, Prenatal Exposure Delayed Effects/chemically induced, Child Behavior, Reproductive health and childbirth, Medical and Health Sciences, Mathematical Sciences, Cohort Studies, 0302 clinical medicine, CHILD, DIFFICULTIES QUESTIONNAIRE, Pregnancy, Child Behavior Disorders/chemically induced, Child, acetaminophen, Pediatric, 2. Zero hunger, Analgesics, DNBC, Analgesics, Non-Narcotic, 3. Good health, PREGNANCY, Prenatal Exposure Delayed Effects, STRENGTHS, Female, Analgesics, Non-Narcotic/adverse effects, Acetaminophen/adverse effects, behavioral problems, Pediatric Research Initiative, Child Behavior/drug effects, Child Behavior Disorders, NEURODEVELOPMENT, 03 medical and health sciences, Clinical Research, Non-Narcotic, Behavioral and Social Science, Humans, Patient Reported Outcome Measures, Acetaminophen, PARACETAMOL ACETAMINOPHEN, Prevention, MATERNAL USE, Good Health and Well Being, ACETYLSALICYLIC-ACID, THE-COUNTER MEDICATIONS, ADOLESCENT AGREEMENT
File Description: application/pdf
Access URL: https://escholarship.org/content/qt8v19p4mx/qt8v19p4mx.pdf?t=ql2h9l
https://pubmed.ncbi.nlm.nih.gov/33230558
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248972
https://escholarship.org/uc/item/8v19p4mx
https://escholarship.org/content/qt8v19p4mx/qt8v19p4mx.pdf?t=ql2h9l
https://academic.oup.com/aje/article-abstract/190/6/1009/5999103
http://europepmc.org/article/MED/33230558
https://www.ncbi.nlm.nih.gov/pubmed/33230558
https://escholarship.org/uc/item/8v19p4mx -
17
Authors:
Source: Revue médicale suisse, Vol. 16, No 682 (2020) pp. 357-360
Subject Terms: ddc:618, Tobacco Products/adverse effects, Prenatal Exposure Delayed Effects/chemically induced, ddc:616.07, 616.07, Electronic Nicotine Delivery Systems, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Smoking/adverse effects, Humans, Female, Switzerland, Maternal Exposure/adverse effects, Nicotine/adverse effects
File Description: application/pdf
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18
Authors: et al.
Source: Ren, T, Lee, M Y P, Li, F & Li, J 2023, 'Prenatal Carbamazepine Exposure and Academic Performance in Adolescents : A Population-Based Cohort Study', Neurology, vol. 100, no. 7, pp. e728-e738. https://doi.org/10.1212/WNL.0000000000201529
Subject Terms: Anticonvulsants/adverse effects, Adolescent, Valproic Acid, 4. Education, Prenatal Exposure Delayed Effects/chemically induced, Carbamazepine/adverse effects, Mothers, Lamotrigine, 3. Good health, Cohort Studies, Benzodiazepines, 03 medical and health sciences, Carbamazepine, 0302 clinical medicine, Pregnancy, Prenatal Exposure Delayed Effects, Academic Performance, Humans, Female, Anticonvulsants, Child
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19
Authors: et al.
Source: Clemmensen, P J, Brix, N, Schullehner, J, Ernst, A, Harrits Lunddorf, L L, Bjerregaard, A A, Halldorsson, T I, Olsen, S F, Hansen, B, Stayner, L T, Kolstad, H A, Sigsgaard, T & Ramlau-Hansen, C H 2023, 'Prenatal exposure to nitrosatable drugs and timing of puberty in sons and daughters : A nationwide cohort study', International Journal of Hygiene and Environmental Health, vol. 254, 114271. https://doi.org/10.1016/j.ijheh.2023.114271
Subject Terms: Nitrate, Nitrosatable drugs, Pregnancy, Prenatal, Puberty, Humans, Nuclear Family, Nitrates, Mothers, Antioxidants, Nitroso Compounds/adverse effects, Prenatal Exposure Delayed Effects/chemically induced, Female, Nitrites/adverse effects, Child, Cohort Studies
File Description: application/pdf
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20
Authors: et al.
Source: Dreier, J W, Bjørk, M-H, Alvestad, S, Gissler, M, Igland, J, Leinonen, M K, Sun, Y, Zoega, H, Cohen, J M, Furu, K, Tomson, T & Christensen, J 2023, 'Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders', JAMA Neurology, vol. 80, no. 6, 568-577, pp. 568-577. https://doi.org/10.1001/jamaneurol.2023.0674
Subject Terms: Adolescent, Anticonvulsants/therapeutic use, Attention Deficit Disorder with Hyperactivity/epidemiology, Carbamazepine/therapeutic use, Child, Preschool, Epilepsy/drug therapy, Female, Humans, Incidence, Lamotrigine/therapeutic use, Levetiracetam/therapeutic use, Male, Oxcarbazepine/therapeutic use, Pregnancy, Prenatal Exposure Delayed Effects/chemically induced, Prospective Studies, Topiramate/therapeutic use, Valproic Acid/therapeutic use
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