Suchergebnisse - "Potassium"

Bioavailability of Magnesium and Potassium Salts Used as Potential Substitutes for Sodium Chloride in Human Nutrition - A Review.

Autoren: Merschmann R Burgmer C Eckert GP et al.

Quelle: Molecular nutrition & food research [Mol Nutr Food Res] 2025 Nov; Vol. 69 (22), pp. e70227. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101231818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-4133 (Electronic) Linking ISSN: 16134125 NLM ISO Abbreviation: Mol Nutr Food Res Subsets: MEDLINE

MeSH-Schlagworte: Magnesium*/pharmacokinetics , Magnesium Compounds*/pharmacokinetics , Potassium Chloride*/pharmacokinetics , Potassium*/pharmacokinetics, Humans ; Biological Availability ; Dietary Supplements ; Potassium Citrate/pharmacokinetics ; Magnesium Chloride/pharmacokinetics ; Hypertension ; Sodium Chloride, Dietary ; Magnesium Oxide/pharmacokinetics ; Organometallic Compounds ; Citric Acid

Highly Efficient Artificial Potassium Ion Channels Constructed via Supramolecular Cooperativity.

Autoren: Xu Z Zhang C Lin Z et al.

Quelle: ACS sensors [ACS Sens] 2025 Oct 24; Vol. 10 (10), pp. 8027-8035. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101669031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3694 (Electronic) Linking ISSN: 23793694 NLM ISO Abbreviation: ACS Sens Subsets: MEDLINE

MeSH-Schlagworte: Potassium Channels*/chemistry , Potassium Channels*/metabolism , Biomimetic Materials*/chemistry , Biomimetic Materials*/chemical synthesis, Potassium/metabolism ; Potassium/chemistry ; Hydrogen Bonding ; Ion Transport

Role of Kir7.1 K ⁺ channel in retinal pigment epithelium probed in a Kir7.1-M125R-expressing mutant mouse.

Autoren: Vera E Henao JC Cid LP et al.

Quelle: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2025 Dec 01; Vol. 329 (6), pp. C1873-C1879. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

MeSH-Schlagworte: Retinal Pigment Epithelium*/metabolism , Potassium Channels, Inwardly Rectifying*/genetics , Potassium Channels, Inwardly Rectifying*/metabolism, Animals ; Mice ; Potassium/metabolism ; Membrane Potentials/physiology ; Mutation ; Mice, Inbred C57BL ; Electroretinography ; Mice, Transgenic

Hypomagnesaemia-associated hypokalaemia requires activation of both ENaC and ROMK.

Autoren: Maeoka Y Duan XP Zhang CB et al.

Quelle: The Journal of physiology [J Physiol] 2025 Nov; Vol. 603 (22), pp. 7365-7382. Date of Electronic Publication: 2025 Oct 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

MeSH-Schlagworte: Epithelial Sodium Channels*/metabolism , Hypokalemia*/metabolism , Hypokalemia*/etiology , Hypokalemia*/blood , Magnesium*/blood , Potassium Channels, Inwardly Rectifying*/metabolism , Magnesium Deficiency*/metabolism , Magnesium Deficiency*/complications, Animals ; Mice, Inbred C57BL ; Potassium/blood ; Potassium/metabolism ; Mice ; Male ; Sodium/metabolism ; Kidney Tubules, Distal/metabolism

Role of BK channels and Kv4.2 channels in the electrophysiological properties of Merkel cells in rat whisker hair follicles.

Autoren: Yamada A Gu J

Quelle: Journal of neurophysiology [J Neurophysiol] 2025 Nov 01; Vol. 134 (5), pp. 1762-1773. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

MeSH-Schlagworte: Large-Conductance Calcium-Activated Potassium Channels*/metabolism , Large-Conductance Calcium-Activated Potassium Channels*/antagonists & inhibitors , Large-Conductance Calcium-Activated Potassium Channels*/physiology , Merkel Cells*/physiology , Merkel Cells*/drug effects , Merkel Cells*/metabolism , Hair Follicle*/physiology , Hair Follicle*/cytology , Hair Follicle*/drug effects , Vibrissae*/physiology , Vibrissae*/cytology , Shal Potassium Channels*/metabolism , Shal Potassium Channels*/antagonists & inhibitors , Shal Potassium Channels*/physiology, Animals ; Rats ; Potassium Channel Blockers/pharmacology ; Rats, Sprague-Dawley ; Action Potentials/drug effects ; Male ; Tetraethylammonium/pharmacology ; Peptides/pharmacology ; Membrane Potentials ; Patch-Clamp Techniques

K V 11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets.

Autoren: Sala C Iorio J Duranti C et al.

Quelle: Pharmacological research [Pharmacol Res] 2025 Nov; Vol. 221, pp. 107992. Date of Electronic Publication: 2025 Oct 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

MeSH-Schlagworte: Ether-A-Go-Go Potassium Channels*/metabolism , Lymphoma, Large B-Cell, Diffuse*/metabolism , Lymphoma, Large B-Cell, Diffuse*/pathology , Lymphoma, Large B-Cell, Diffuse*/drug therapy , ERG1 Potassium Channel*/metabolism, Humans ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Kv1.3 Potassium Channel/metabolism

Biomimetic KcsA channels enabled by 1D MOF-in-2D COF.

Autoren: Sun Q Dou P Du J et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 14; Vol. 16 (1), pp. 9099. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Potassium Channels*/chemistry , Potassium Channels*/metabolism , Metal-Organic Frameworks*/chemistry , Biomimetic Materials*/chemistry , Biomimetics*/methods , Bacterial Proteins*/chemistry , Bacterial Proteins*/metabolism, Potassium/chemistry ; Potassium/metabolism ; Sodium/chemistry ; Sodium/metabolism

A physiologically-relevant intermediate state structure of a voltage-gated potassium channel.

Autoren: Kyriakis E Sastre D Eldstrom J et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8814. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: KCNQ1 Potassium Channel*/chemistry , KCNQ1 Potassium Channel*/metabolism , KCNQ1 Potassium Channel*/genetics , KCNQ1 Potassium Channel*/ultrastructure , Potassium Channels, Voltage-Gated*/chemistry , Potassium Channels, Voltage-Gated*/metabolism, Cryoelectron Microscopy ; Humans ; Ion Channel Gating ; Animals ; Mutation ; Models, Molecular ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Potassium/metabolism

KCNQ3 activation by the naturally occurring phenol, eugenol.

Autoren: Rivera-Ruedas A Medina-Vilchis A Romero-Tovar J et al.

Quelle: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2025 Oct 01; Vol. 103 (10), pp. 325-333. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1205-7541 (Electronic) Linking ISSN: 00084212 NLM ISO Abbreviation: Can J Physiol Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Eugenol*/pharmacology , Eugenol*/metabolism , KCNQ3 Potassium Channel*/metabolism , KCNQ3 Potassium Channel*/chemistry , KCNQ3 Potassium Channel*/genetics , KCNQ3 Potassium Channel*/agonists, Animals ; TRPV Cation Channels/metabolism ; Molecular Docking Simulation ; Humans ; Diclofenac/pharmacology ; HEK293 Cells ; KCNQ2 Potassium Channel/metabolism ; KCNQ2 Potassium Channel/genetics ; Mice

Pharmacological inhibition of KSper impairs flagellar pH homeostasis of human spermatozoa.

Autoren: Ji N Wang X Zeng X et al.

Quelle: Andrology [Andrology] 2025 Oct; Vol. 13 (7), pp. 1805-1815. Date of Electronic Publication: 2024 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-2927 (Electronic) Linking ISSN: 20472919 NLM ISO Abbreviation: Andrology Subsets: MEDLINE

MeSH-Schlagworte: Spermatozoa*/drug effects , Spermatozoa*/metabolism , Sperm Tail*/drug effects , Sperm Tail*/metabolism , Potassium Channels*/metabolism , Large-Conductance Calcium-Activated Potassium Channels*/antagonists & inhibitors , Large-Conductance Calcium-Activated Potassium Channels*/metabolism, Male ; Humans ; Hydrogen-Ion Concentration ; Homeostasis/drug effects ; Quinidine/pharmacology ; Membrane Potentials/drug effects ; Sperm Motility/drug effects ; Adult ; Nerve Tissue Proteins ; Potassium Channels, Tandem Pore Domain

Targeting Ca ²⁺ -activated K ⁺ channels in glioma.

Autoren: Zhang Y Ribas HT Winnischofer SMB et al.

Quelle: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Oct; Vol. 1871 (7), pp. 167950. Date of Electronic Publication: 2025 Jun 06.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

MeSH-Schlagworte: Glioma*/metabolism , Glioma*/pathology , Glioma*/drug therapy , Glioma*/genetics , Brain Neoplasms*/metabolism , Brain Neoplasms*/pathology , Brain Neoplasms*/drug therapy , Brain Neoplasms*/genetics , Potassium Channels, Calcium-Activated*/metabolism , Potassium Channels, Calcium-Activated*/genetics , Potassium Channels, Calcium-Activated*/antagonists & inhibitors , Glioblastoma*/metabolism , Glioblastoma*/pathology , Glioblastoma*/drug therapy , Glioblastoma*/genetics, Humans ; Animals ; Gene Expression Regulation, Neoplastic/drug effects ; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism ; Intermediate-Conductance Calcium-Activated Potassium Channels/genetics ; Cell Proliferation

Simple methods for estimating the maximum 24-hour urinary potassium excretion in kidney failure without replacement therapy patients.

Autoren: Zhang D Wang Y Jiang S et al.

Quelle: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2445157. Date of Electronic Publication: 2025 Jan 08.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH-Schlagworte: Hyperkalemia*/urine , Hyperkalemia*/etiology , Potassium*/urine, Humans ; Female ; Male ; Middle Aged ; Aged ; Renal Insufficiency/urine ; Potassium, Dietary/urine ; Linear Models ; Adult

K ⁺ channels as key modulators of in vitro high-frequency oscillations associated with interictal epileptiform activity.

Autoren: Kalogeropoulos K Psarropoulou C

Quelle: Neuroscience [Neuroscience] 2025 Nov 28; Vol. 589, pp. 84-95. Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

MeSH-Schlagworte: Hippocampus*/drug effects , Hippocampus*/physiopathology , Potassium Channels*/metabolism , Potassium Channels*/physiology , Epilepsy*/physiopathology , Epilepsy*/metabolism, Animals ; Potassium Channel Blockers/pharmacology ; Male ; Bicuculline/pharmacology ; Bicuculline/analogs & derivatives ; Rats, Wistar ; Tetraethylammonium/pharmacology ; Pentylenetetrazole ; Rats ; GABA-A Receptor Antagonists/pharmacology ; Seizures/physiopathology ; Status Epilepticus/physiopathology ; Status Epilepticus/chemically induced ; In Vitro Techniques

Activation of Kv11.1 potassium channel suppresses non-small cell lung cancer growth by promoting c-Myc degradation.

Autoren: Eskandari N Delisi D O'Neil R et al.

Quelle: Communications biology [Commun Biol] 2025 Nov 20; Vol. 8 (1), pp. 1615. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

MeSH-Schlagworte: Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Carcinoma, Non-Small-Cell Lung*/metabolism , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/genetics , ERG1 Potassium Channel*/metabolism , ERG1 Potassium Channel*/genetics , ERG1 Potassium Channel*/agonists , Proto-Oncogene Proteins c-myc*/metabolism , Proto-Oncogene Proteins c-myc*/genetics, Humans ; Proteolysis ; Animals ; Cell Line, Tumor ; Cell Proliferation ; Mice ; Adenocarcinoma of Lung/metabolism ; A549 Cells ; Gene Expression Regulation, Neoplastic ; Ether-A-Go-Go Potassium Channels

Excess dietary potassium raises blood pressure in male mice by an aldosterone-dependent increase in ENaC.

Autoren: Assmus AM Odgaard LN Garrelds IM et al.

Quelle: Communications biology [Commun Biol] 2025 Nov 17; Vol. 8 (1), pp. 1581. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

MeSH-Schlagworte: Aldosterone*/metabolism , Epithelial Sodium Channels*/metabolism , Blood Pressure*/drug effects , Potassium, Dietary*/adverse effects , Potassium, Dietary*/administration & dosage , Hypertension*/metabolism , Hypertension*/physiopathology , Hypertension*/etiology, Animals ; Male ; Mice ; Mice, Inbred C57BL ; Potassium

Nebivolol prevents coronary artery spasm by upregulating voltage-gated potassium channels via protein kinase A.

Autoren: Yang J Zhou H Wang Y et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Nov 05; Vol. 1006, pp. 178157. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Coronary Vessels*/drug effects , Coronary Vessels*/metabolism , Coronary Vessels*/cytology , Nebivolol*/pharmacology , Cyclic AMP-Dependent Protein Kinases*/metabolism , Up-Regulation*/drug effects , Potassium Channels, Voltage-Gated*/metabolism, Animals ; Male ; Rats ; Rats, Sprague-Dawley ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Kv1.2 Potassium Channel/metabolism ; Vasoconstriction/drug effects

Investigating of tomato response to different concentrations of potassium in the nutrient solution and foliar application of calcium and silicon.

Autoren: Roosta HR Hashemi SZ Moradi M

Quelle: Scientific reports [Sci Rep] 2025 Nov 03; Vol. 15 (1), pp. 38399. Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Solanum lycopersicum*/growth & development , Solanum lycopersicum*/drug effects , Solanum lycopersicum*/metabolism , Silicon*/pharmacology , Potassium*/pharmacology , Potassium*/metabolism , Calcium*/pharmacology , Calcium*/metabolism, Plant Leaves/drug effects ; Plant Leaves/growth & development ; Plant Leaves/metabolism ; Nitrates/pharmacology ; Fruit/drug effects ; Fruit/growth & development ; Plant Roots/drug effects ; Plant Roots/growth & development ; Potassium Compounds/pharmacology ; Hydroponics ; Nutrients ; Calcium Compounds/pharmacology ; Sulfates/pharmacology ; Biomass ; Plant Shoots/drug effects ; Plant Shoots/growth & development

[Efficient expression and biological activity characterization of human potassium channel K V 3.1 in an Escherichia coli cell-free protein synthesis system].

Autoren: Zhao Z Zhou T Song Y et al.

Quelle: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2025 Nov; Vol. 41 (11), pp. 1000-1006.

Publikationsart: English Abstract; Journal Article

Info zur Zeitschrift: Publisher: Xi bao yu fen zi mian yi xue za zhi bian ji bu Country of Publication: China NLM ID: 101139110 Publication Model: Print Cited Medium: Print ISSN: 1007-8738 (Print) Linking ISSN: 10078738 NLM ISO Abbreviation: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Escherichia coli*/genetics , Escherichia coli*/metabolism , Shaw Potassium Channels*/genetics , Shaw Potassium Channels*/chemistry , Shaw Potassium Channels*/metabolism , Shaw Potassium Channels*/biosynthesis , Protein Biosynthesis*, Humans ; Cell-Free System ; Circular Dichroism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/genetics ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Membrane Potentials ; Shab Potassium Channels

Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury.

Autoren: Barbay T Pecchi E Ramirez-Franco J et al.

Quelle: Brain : a journal of neurology [Brain] 2025 Oct 03; Vol. 148 (10), pp. 3576-3591.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

MeSH-Schlagworte: Potassium Channels, Inwardly Rectifying*/metabolism , Astrocytes*/metabolism , Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/complications , Muscle Spasticity*/metabolism , Muscle Spasticity*/etiology, Animals ; Kcnj10 Channel ; Mice ; Mice, Inbred C57BL ; Disease Models, Animal ; Female ; Potassium/metabolism

Targeting KCNN4 channels modulates microglial activation and apoptosis in a PD-relevant inflammatory model.

Autoren: Hung HY Li IH Lin YN et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118526. Date of Electronic Publication: 2025 Sep 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/drug effects , Microglia*/metabolism , Microglia*/pathology , Intermediate-Conductance Calcium-Activated Potassium Channels*/antagonists & inhibitors , Intermediate-Conductance Calcium-Activated Potassium Channels*/metabolism , Apoptosis*/drug effects , Parkinson Disease*/drug therapy , Parkinson Disease*/metabolism, Animals ; Male ; Mice ; Lipopolysaccharides ; Disease Models, Animal ; Mice, Inbred C57BL ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Potassium Channel Blockers/pharmacology ; Neuroinflammatory Diseases/metabolism ; Neuroinflammatory Diseases/drug therapy ; Pyrazoles