Suchergebnisse - "Poly I-C"

Polyinosinic Polycytidylic Acid (poly I:C) Induces Neuronal Cell Death Through NF-κB-Mediated Inflammation in Human Microglia and Neuroinflammation-Induced Cognitive Impairment in Mice.

Autoren: Altahrawi AY James AW Shah ZA

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Nov 19; Vol. 63 (1), pp. 82. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Poly I-C*/toxicity , Microglia*/drug effects , Microglia*/metabolism , Microglia*/pathology , NF-kappa B*/metabolism , Neurons*/drug effects , Neurons*/pathology , Neurons*/metabolism , Neuroinflammatory Diseases*/pathology , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/complications , Cognitive Dysfunction*/pathology , Cognitive Dysfunction*/metabolism , Inflammation*/pathology , Inflammation*/metabolism , Inflammation*/complications, Animals ; Humans ; Mice ; Cell Death/drug effects ; Male ; Cytokines/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Mice, Inbred C57BL ; Inflammasomes/metabolism ; Apoptosis/drug effects

Perioperative poly(I:C) reverses accelerated tumor growth after surgery in neuroblastoma.

Autoren: Mao C Poimenidou M McAllister D et al.

Quelle: ImmunoHorizons [Immunohorizons] 2025 Nov 09; Vol. 9 (11).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 101708159 Publication Model: Print Cited Medium: Internet ISSN: 2573-7732 (Electronic) Linking ISSN: 25737732 NLM ISO Abbreviation: Immunohorizons Subsets: MEDLINE

MeSH-Schlagworte: Neuroblastoma*/surgery , Neuroblastoma*/pathology , Neuroblastoma*/immunology , Neuroblastoma*/drug therapy , Poly I-C*/pharmacology , Poly I-C*/therapeutic use, Animals ; Mice ; Humans ; Disease Models, Animal ; Cell Line, Tumor ; N-Myc Proto-Oncogene Protein/genetics ; Female ; Macrophages/immunology ; Dendritic Cells/immunology

Impaired Gq signaling underlies oxytocin hyporesponsiveness in LPS and poly I:C-induced preterm labor in mice.

Autoren: Ravi Prakash G Vaidhya A Rathore LS et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 05; Vol. 1008, pp. 178340. Date of Electronic Publication: 2025 Nov 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Oxytocin*/pharmacology , Lipopolysaccharides*/pharmacology , Signal Transduction*/drug effects , Obstetric Labor, Premature*/chemically induced , Obstetric Labor, Premature*/metabolism , Obstetric Labor, Premature*/physiopathology , Poly I-C*/pharmacology , GTP-Binding Protein alpha Subunits, Gq-G11*/metabolism, Animals ; Female ; Mice ; Pregnancy ; Receptors, Oxytocin/metabolism ; Uterine Contraction/drug effects ; Cytokines/metabolism ; Matrix Metalloproteinase 9/metabolism ; Uterus/drug effects ; Uterus/metabolism

IFN-γ enhances Poly(I:C)-induced necroptosis and immunogenic cell death via TLR3 upregulation in cholangiocarcinoma cells.

Autoren: Sae-Fung A Lomphithak T Duangthim N et al.

Quelle: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 Nov 01; Vol. 214, pp. 107274. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Cholangiocarcinoma*/metabolism , Cholangiocarcinoma*/drug therapy , Cholangiocarcinoma*/genetics , Cholangiocarcinoma*/immunology , Cholangiocarcinoma*/pathology , Toll-Like Receptor 3*/metabolism , Toll-Like Receptor 3*/genetics , Poly I-C*/pharmacology , Necroptosis*/drug effects , Interferon-gamma*/pharmacology , Interferon-gamma*/metabolism , Bile Duct Neoplasms*/drug therapy , Bile Duct Neoplasms*/metabolism , Bile Duct Neoplasms*/immunology , Bile Duct Neoplasms*/genetics , Bile Duct Neoplasms*/pathology , Immunogenic Cell Death*/drug effects, Humans ; Cell Line, Tumor ; Up-Regulation/drug effects ; Interferon Regulatory Factor-1/metabolism ; Interferon Regulatory Factor-1/genetics

Prenatal poly(I:C) exposure, rather than altered maternal care, causes offspring behavioural and cognitive deficits in a rat model of neurodevelopmental disorders.

Autoren: Potter HG Woods RM Lorusso JM et al.

Quelle: Brain, behavior, and immunity [Brain Behav Immun] 2025 Oct; Vol. 129, pp. 186-195. Date of Electronic Publication: 2025 Jun 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

MeSH-Schlagworte: Prenatal Exposure Delayed Effects*/metabolism , Poly I-C*/pharmacology , Neurodevelopmental Disorders*/metabolism , Neurodevelopmental Disorders*/chemically induced , Cognitive Dysfunction* , Maternal Behavior*/drug effects , Maternal Behavior*/physiology, Animals ; Female ; Pregnancy ; Rats ; Rats, Wistar ; Male ; Disease Models, Animal ; Behavior, Animal/drug effects ; Cognition/drug effects ; Prefrontal Cortex/metabolism

Ex vivo analysis of the impact of dsRNA complexed to cationic phytoglycogen nanoparticles on the innate immune response in rainbow trout.

Autoren: Oberhoffner SJ Velázquez Pérez J Richardson SA et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Nov; Vol. 166, pp. 110634. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Oncorhynchus mykiss*/immunology , Immunity, Innate*/drug effects , RNA, Double-Stranded*/pharmacology , RNA, Double-Stranded*/immunology , Poly I-C*/pharmacology , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Fish Diseases*/immunology, Animals

Prenatal Poly I:C exposure affects tryptophan-kynurenine metabolism associated with intestinal microbiome in female juvenile rats.

Autoren: Yang L Chen H Zeng M et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Oct 01; Vol. 16, pp. 1669845. Date of Electronic Publication: 2025 Oct 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C* , Tryptophan*/metabolism , Gastrointestinal Microbiome*/drug effects , Prenatal Exposure Delayed Effects*/metabolism , Kynurenine*/metabolism, Animals ; Female ; Pregnancy ; Rats ; Prefrontal Cortex/metabolism ; Behavior, Animal ; Male ; Anxiety

An in vitro study of type I interferon and inflammatory markers induced by dsRNA and dsRNA-phytoglycogen in rainbow trout.

Autoren: Jenik K Rodríguez-Ramos T Sanyaolu A et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Oct; Vol. 165, pp. 110524. Date of Electronic Publication: 2025 Jun 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Oncorhynchus mykiss*/immunology , Oncorhynchus mykiss*/genetics , Poly I-C*/pharmacology , RNA, Double-Stranded*/pharmacology , Immunity, Innate*/drug effects , Interferon Type I*/genetics , Interferon Type I*/metabolism , Interferon Type I*/immunology , Fish Proteins*/genetics , Fish Proteins*/metabolism , Fish Proteins*/immunology, Animals ; Cell Line ; Biomarkers/metabolism ; Fish Diseases/immunology

Dendritic Cell-Cytokine-Induced Killer Cells Co-Loaded with WT1/MUC1/Poly(I:C) Enhance Antitumor Immune Responses In Vitro and In Vivo.

Autoren: Liu H Wang C Chang H et al.

Quelle: Biomolecules [Biomolecules] 2025 Sep 24; Vol. 15 (10). Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Poly I-C*/immunology , Mucin-1*/immunology , Dendritic Cells*/immunology , Cytokine-Induced Killer Cells*/immunology , WT1 Proteins*/immunology, Humans ; Animals ; Cell Line, Tumor ; Mice ; Xenograft Model Antitumor Assays ; Apoptosis ; Stomach Neoplasms/immunology ; Stomach Neoplasms/therapy

A Phase Ib Study of Indirect Immunization with Oregovomab and Toll-like-Receptor-3 Stimulation with Hiltonol ^® in Patients with Recurrent Platinum-Resistant Ovarian Cancer.

Autoren: Holloway RW Temkin SM Gordon SW et al.

Quelle: Current oncology (Toronto, Ont.) [Curr Oncol] 2025 Sep 24; Vol. 32 (10). Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article; Clinical Trial, Phase I

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Electronic Cited Medium: Internet ISSN: 1718-7729 (Electronic) Linking ISSN: 11980052 NLM ISO Abbreviation: Curr Oncol Subsets: MEDLINE

MeSH-Schlagworte: Neoplasm Recurrence, Local*/drug therapy , Neoplasm Recurrence, Local*/immunology , Neoplasm Recurrence, Local*/mortality , Neoplasm Recurrence, Local*/pathology , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/mortality , Ovarian Neoplasms*/pathology , Poly I-C*/therapeutic use , Poly I-C*/administration & dosage , Polylysine*/analogs & derivatives , Polylysine*/therapeutic use , Polylysine*/administration & dosage , Polylysine*/analogs & derivatives , Toll-Like Receptor 3*/agonists, Adult ; Aged ; Female ; Humans ; Middle Aged ; Adjuvants, Immunologic/therapeutic use ; Drug Resistance, Neoplasm ; Carboxymethylcellulose Sodium/analogs & derivatives

A co-culture system to study the effects of Poly I:C-activated microglia on the differentiation of murine primary neural stem cells.

Autoren: Manitz MP Violou K Hedstück M et al.

Quelle: In vitro cellular & developmental biology. Animal [In Vitro Cell Dev Biol Anim] 2025 Sep; Vol. 61 (8), pp. 991-1004. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Germany NLM ID: 9418515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-706X (Electronic) Linking ISSN: 10712690 NLM ISO Abbreviation: In Vitro Cell Dev Biol Anim Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Microglia*/drug effects , Microglia*/cytology , Microglia*/metabolism , Cell Differentiation*/drug effects , Neural Stem Cells*/cytology , Neural Stem Cells*/drug effects , Neural Stem Cells*/metabolism, Animals ; Coculture Techniques/methods ; Mice ; Cell Line ; Neurogenesis/drug effects ; Cytokines/metabolism

M1 Macrophage Extracellular Vesicles and TLR3 Agonist Nanoparticles Down-Regulate Immunosuppression and Metastasis via AKT/TAM in Triple-Negative Breast Cancer.

Autoren: Souza SVP Aguiar ACV Albuquerque ECS et al.

Quelle: Molecular carcinogenesis [Mol Carcinog] 2025 Sep; Vol. 64 (9), pp. 1450-1461. Date of Electronic Publication: 2025 Jun 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2744 (Electronic) Linking ISSN: 08991987 NLM ISO Abbreviation: Mol Carcinog Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/immunology , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/metabolism , Toll-Like Receptor 3*/agonists , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Macrophages*/metabolism , Macrophages*/immunology , Macrophages*/drug effects , Proto-Oncogene Proteins c-akt*/metabolism , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/immunology , Poly I-C*/pharmacology , Poly I-C*/administration & dosage, Animals ; Female ; Mice ; Tumor Microenvironment/immunology ; Tumor Microenvironment/drug effects ; Humans ; RAW 264.7 Cells ; Cell Line, Tumor

Poly(I:C) stimulates cytokine production, but not cell migration, in an extravillous trophoblast cell line.

Autoren: Hameete BC Hogenkamp A Plösch T et al.

Quelle: Journal of reproductive immunology [J Reprod Immunol] 2025 Sep; Vol. 171, pp. 104632. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 8001906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7603 (Electronic) Linking ISSN: 01650378 NLM ISO Abbreviation: J Reprod Immunol Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Poly I-C*/immunology , Trophoblasts*/immunology , Trophoblasts*/drug effects , Cytokines*/metabolism, Humans ; Cell Movement/drug effects ; Female ; Pregnancy ; Cell Line ; Toll-Like Receptor 3/agonists ; Toll-Like Receptor 3/metabolism ; Chorionic Gonadotropin/metabolism ; Progesterone/metabolism ; Extravillous Trophoblasts

PolyIC as an adjuvant outperforms anti-VEGF in combination with anti-PD-L1 therapy in mouse liver tumor models.

Autoren: Ji Y Lu LC Zhuang H et al.

Quelle: Hepatology communications [Hepatol Commun] 2025 Aug 15; Vol. 9 (9). Date of Electronic Publication: 2025 Aug 15 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

MeSH-Schlagworte: Vascular Endothelial Growth Factor A*/antagonists & inhibitors , Immune Checkpoint Inhibitors*/pharmacology , Immune Checkpoint Inhibitors*/therapeutic use , B7-H1 Antigen*/antagonists & inhibitors , Poly I-C*/pharmacology , Poly I-C*/therapeutic use , Liver Neoplasms*/drug therapy , Liver Neoplasms*/immunology, Animals ; Mice ; Disease Models, Animal ; Cell Line, Tumor ; Adjuvants, Immunologic/pharmacology ; Mice, Inbred C57BL ; Angiogenesis Inhibitors/pharmacology ; CD8-Positive T-Lymphocytes/immunology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology

Differential Effects of Prenatal Poly I:C Exposure and Antipsychotics on NMDA/GABA Receptors and GSK3β-Mediated Signaling in the Dorsal Raphe Nucleus of Female Rats.

Autoren: Chen S Lian J Su Y et al.

Quelle: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2025 Aug; Vol. 39 (4), pp. e70033.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print Cited Medium: Internet ISSN: 1472-8206 (Electronic) Linking ISSN: 07673981 NLM ISO Abbreviation: Fundam Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Glycogen Synthase Kinase 3 beta*/metabolism , Receptors, N-Methyl-D-Aspartate*/metabolism , Antipsychotic Agents*/pharmacology , Dorsal Raphe Nucleus*/drug effects , Dorsal Raphe Nucleus*/metabolism , Poly I-C*/toxicity , Poly I-C*/pharmacology , Prenatal Exposure Delayed Effects*, Animals ; Female ; Signal Transduction/drug effects ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Receptors, GABA-A/metabolism ; Risperidone/pharmacology ; Olanzapine/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Male ; Cyclic AMP Response Element-Binding Protein/metabolism ; Receptors, GABA/metabolism

High-fat intake during lactation ameliorates cardiac fatty acid metabolic disorders and dysfunction in mouse offspring undergoing prenatal poly (I:C) stimulation.

Autoren: Song L Meng M Ji Y et al.

Quelle: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Jul; Vol. 46 (7), pp. 1920-1929. Date of Electronic Publication: 2025 Feb 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

MeSH-Schlagworte: Diet, High-Fat*/adverse effects , Lactation* , Fatty Acids*/metabolism , Prenatal Exposure Delayed Effects*/metabolism , Poly I-C* , Myocardium*/metabolism , Metabolic Diseases*/metabolism, Animals ; Female ; Pregnancy ; Mice ; Mice, Inbred C57BL ; Male ; Energy Metabolism ; Heart/drug effects ; Heart/physiopathology

Comparison of cellular responses of cultured fibroblasts from Iriomote wild cats and domestic cats exposure to polyinosinic:polycytidylic acid.

Autoren: Katayama M Kataoka A Fukuda T et al.

Quelle: PloS one [PLoS One] 2025 Sep 25; Vol. 20 (9), pp. e0332954. Date of Electronic Publication: 2025 Sep 25 (Print Publication: 2025).

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/cytology, Animals ; Cats ; Interferon-Induced Helicase, IFIH1/genetics ; Interferon-Induced Helicase, IFIH1/metabolism ; Toll-Like Receptor 3/genetics ; Toll-Like Receptor 3/metabolism ; Cells, Cultured ; Animals, Wild ; DEAD Box Protein 58/genetics ; DEAD Box Protein 58/metabolism ; Gene Expression Regulation/drug effects

Evolutionary insights and poly(I:C)-induced changes in expression and m ⁶ A modifications of il17ra and il17rc in Miichthysmiiuy.

Autoren: Tian R Geng S Lv X et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Jul; Vol. 162, pp. 110343. Date of Electronic Publication: 2025 Apr 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Poly I-C*/pharmacology , Receptors, Interleukin-17*/genetics , Receptors, Interleukin-17*/immunology , Receptors, Interleukin-17*/chemistry , Fish Proteins*/genetics , Fish Proteins*/immunology , Fish Proteins*/chemistry , Perciformes*/immunology , Perciformes*/genetics , Gene Expression Regulation*/immunology , Immunity, Innate*/genetics, Animals ; Adenosine/analogs & derivatives ; Adenosine/metabolism ; Phylogeny

Poly-IC Alleviates Nitroglycerin-Induced Migraine by Inhibiting Neuroinflammation via TLR3/TRIF Signaling Pathway.

Autoren: Hong Y Ma M Li C et al.

Quelle: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2025 May; Vol. 31 (5), pp. e70444.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

MeSH-Schlagworte: Toll-Like Receptor 3*/metabolism , Toll-Like Receptor 3*/antagonists & inhibitors , Poly I-C*/pharmacology , Poly I-C*/therapeutic use , Signal Transduction*/drug effects , Signal Transduction*/physiology , Migraine Disorders*/chemically induced , Migraine Disorders*/drug therapy , Migraine Disorders*/metabolism , Adaptor Proteins, Vesicular Transport*/metabolism , Neuroinflammatory Diseases*/drug therapy , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/chemically induced, Animals ; Male ; Nitroglycerin/toxicity ; Rats ; Rats, Sprague-Dawley ; Cells, Cultured

Local delivery of lipid-based nanoparticles containing microbial nucleic acid for osteoimmunomodulation.

Autoren: Rahmani NR Jahanmard F Hassani Najafabadi A et al.

Quelle: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 May 01; Vol. 208, pp. 107050. Date of Electronic Publication: 2025 Feb 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Oligodeoxyribonucleotides*/administration & dosage , Oligodeoxyribonucleotides*/chemistry , Oligodeoxyribonucleotides*/pharmacology , Poly I-C*/administration & dosage , Poly I-C*/chemistry , Poly I-C*/pharmacology , Lipids*/chemistry, Humans ; Animals ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/immunology ; Rabbits ; Mesenchymal Stem Cells/drug effects ; Osteoblasts/drug effects ; Cells, Cultured ; Cell Differentiation/drug effects ; Cytokines/metabolism ; Osteogenesis/drug effects