Search Results - "Platinum Compounds"

Combination therapy for platinum-resistant ovarian cancer: a novel at-home regimen with envafolimab, lenvatinib, and etoposide.

Authors: Ding B Yu T Zheng S et al.

Source: The oncologist [Oncologist] 2025 Sep 01; Vol. 30 (9).

Publication Type: Journal Article; Clinical Trial, Phase II

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

MeSH Terms: Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/pharmacology , Etoposide*/pharmacology , Etoposide*/therapeutic use , Etoposide*/administration & dosage , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/pathology , Phenylurea Compounds*/pharmacology , Phenylurea Compounds*/therapeutic use , Phenylurea Compounds*/administration & dosage , Quinolines*/pharmacology , Quinolines*/therapeutic use , Quinolines*/administration & dosage , Platinum Compounds*/pharmacology , Platinum Compounds*/therapeutic use, Adult ; Aged ; Female ; Humans ; Middle Aged ; Drug Resistance, Neoplasm/drug effects ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/pathology

Research Progress of Platinum-Based Complexes in Lung Cancer Treatment: Mechanisms, Applications, and Challenges.

Authors: Liang W Huang Y Wang Y et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 18; Vol. 26 (16). Date of Electronic Publication: 2025 Aug 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Lung Neoplasms*/drug therapy , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Organoplatinum Compounds*/therapeutic use , Organoplatinum Compounds*/pharmacology , Organoplatinum Compounds*/chemistry , Platinum*/chemistry , Platinum*/therapeutic use , Platinum Compounds*/therapeutic use, Humans ; Cisplatin/therapeutic use ; Oxaliplatin/therapeutic use ; Animals

Exposure-response relationships for platinum salt sensitization in precious metal refinery workers: a 16-yr retrospective study.

Authors: Smit LAM Jacobs J van Rooy F et al.

Source: Annals of work exposures and health [Ann Work Expo Health] 2025 Jul 15; Vol. 69 (6), pp. 592-601.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101698454 Publication Model: Print Cited Medium: Internet ISSN: 2398-7316 (Electronic) Linking ISSN: 23987308 NLM ISO Abbreviation: Ann Work Expo Health Subsets: MEDLINE

MeSH Terms: Occupational Exposure*/adverse effects , Occupational Exposure*/analysis , Metallurgy* , Platinum*/adverse effects , Platinum Compounds*/adverse effects, Humans ; Retrospective Studies ; Male ; Adult ; Female ; Middle Aged ; Skin Tests ; Air Pollutants, Occupational/analysis ; Air Pollutants, Occupational/adverse effects ; Proportional Hazards Models

Platinum-based chemotherapies-induced nephrotoxicity: mechanisms, potential treatments, and management.

Authors: Shahrahmani F Badamchizadeh S Kaihani F et al.

Source: International urology and nephrology [Int Urol Nephrol] 2025 May; Vol. 57 (5), pp. 1563-1583. Date of Electronic Publication: 2024 Dec 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0262521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2584 (Electronic) Linking ISSN: 03011623 NLM ISO Abbreviation: Int Urol Nephrol Subsets: MEDLINE

MeSH Terms: Antineoplastic Agents*/adverse effects , Acute Kidney Injury*/chemically induced , Acute Kidney Injury*/therapy , Organoplatinum Compounds*/adverse effects , Renal Insufficiency, Chronic*/chemically induced , Renal Insufficiency, Chronic*/therapy , Kidney Diseases*/chemically induced , Kidney Diseases*/therapy , Platinum Compounds*/adverse effects, Humans

"Non-Classical" Platinum Complexes: A Concise Review.

Authors: Bakalova A Ruseva N Cherneva E

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 28; Vol. 26 (13). Date of Electronic Publication: 2025 Jun 28.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Organoplatinum Compounds*/chemistry , Organoplatinum Compounds*/therapeutic use , Organoplatinum Compounds*/pharmacology , Neoplasms*/drug therapy , Platinum*/chemistry , Platinum Compounds*/chemistry, Humans ; Cisplatin/chemistry ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Structure-Activity Relationship ; Animals

Advances in platinum-based cancer therapy: overcoming platinum resistance through rational combinatorial strategies.

Authors: Yusoh NA Ahmad H Vallis KA et al.

Source: Medical oncology (Northwood, London, England) [Med Oncol] 2025 Jun 16; Vol. 42 (7), pp. 262. Date of Electronic Publication: 2025 Jun 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

MeSH Terms: Drug Resistance, Neoplasm*/drug effects , Neoplasms*/drug therapy , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Platinum Compounds*/therapeutic use , Antineoplastic Agents*/therapeutic use , Organoplatinum Compounds*/therapeutic use, Humans

Clinical outcomes of recurrent or metastatic head and neck cancer after failure of platinum and nivolumab: a multicenter retrospective study.

Authors: Watanabe T Oka H Nagashima K et al.

Source: The oncologist [Oncologist] 2025 Mar 10; Vol. 30 (3).

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

MeSH Terms: Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Head and Neck Neoplasms*/drug therapy , Head and Neck Neoplasms*/pathology , Head and Neck Neoplasms*/mortality , Neoplasm Recurrence, Local*/drug therapy , Neoplasm Recurrence, Local*/pathology , Nivolumab*/therapeutic use , Nivolumab*/pharmacology , Squamous Cell Carcinoma of Head and Neck*/drug therapy , Squamous Cell Carcinoma of Head and Neck*/pathology , Squamous Cell Carcinoma of Head and Neck*/secondary , Platinum Compounds*/therapeutic use, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis ; Paclitaxel/therapeutic use ; Retrospective Studies ; Salvage Therapy ; Treatment Failure ; Docetaxel/therapeutic use

Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes.

Authors: Bogas G Ariza A Vázquez-Revuelta P et al.

Source: Allergy [Allergy] 2025 Jan; Vol. 80 (1), pp. 271-286. Date of Electronic Publication: 2024 Aug 31.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE

MeSH Terms: Drug Hypersensitivity*/diagnosis , Drug Hypersensitivity*/immunology , Basophils*/immunology , Basophils*/metabolism , Basophil Degranulation Test*/methods , Taxoids*/adverse effects , Platinum Compounds*/adverse effects , Hypersensitivity, Immediate*/diagnosis , Hypersensitivity, Immediate*/immunology , Antineoplastic Agents*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Prospective Studies ; Skin Tests

Experimental and molecular dynamics simulation study on thermal rectification in multilayer PtSe2.

Authors: Zhao, Haibo Yang, Xiao Shen, Yanan et al.

Source: Journal of Applied Physics. 11/7/2025, Vol. 138 Issue 17, p1-8. 8p.

Subject Terms: *TWO-dimensional materials (Nanotechnology), *PLATINUM compounds, *THERMOELECTRIC apparatus & appliances, *SEMICONDUCTORS, *MOLECULAR dynamics, *TRANSISTORS

Engineering carbon-based nanomaterials for the delivery of platinum compounds: An innovative cancer disarming frontier.

Authors: Rahchamandi SYR Mirhadi E Gheybi F et al.

Source: Environmental research [Environ Res] 2024 Dec 01; Vol. 262 (Pt 2), pp. 119933. Date of Electronic Publication: 2024 Sep 13.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

MeSH Terms: Neoplasms*/drug therapy , Nanostructures* , Platinum Compounds*/chemistry, Humans ; Carbon/chemistry ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Drug Delivery Systems/methods ; Animals

Immune checkpoint inhibitors plus platinum-based chemotherapy compared to platinum-based chemotherapy with or without bevacizumab for first-line treatment of older people with advanced non-small cell lung cancer.

Authors: Orillard E Adhikari A Malouf RS et al.

Source: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2024 Aug 13; Vol. 8. Cochrane AN: CD015495. Date of Electronic Publication: 2024 Aug 13.

Publication Type: Journal Article; Meta-Analysis; Systematic Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100909747 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-493X (Electronic) Linking ISSN: 13616137 NLM ISO Abbreviation: Cochrane Database Syst Rev Subsets: MEDLINE

MeSH Terms: Antineoplastic Combined Chemotherapy Protocols*/administration & dosage , Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Bevacizumab*/administration & dosage , Bevacizumab*/adverse effects , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/mortality , Carcinoma, Non-Small-Cell Lung*/pathology , Immune Checkpoint Inhibitors*/administration & dosage , Immune Checkpoint Inhibitors*/adverse effects , Lung Neoplasms*/drug therapy , Lung Neoplasms*/mortality , Lung Neoplasms*/pathology , Platinum Compounds*/administration & dosage , Platinum Compounds*/adverse effects, Aged ; Humans ; Progression-Free Survival ; Quality of Life ; Randomized Controlled Trials as Topic

Alectinib in Resected ALK -Positive Non-Small-Cell Lung Cancer.

Authors: Wu YL Dziadziuszko R Ahn JS et al.

Corporate Authors: Wu YL Dziadziuszko R Ahn JS et al.

Source: The New England journal of medicine [N Engl J Med] 2024 Apr 11; Vol. 390 (14), pp. 1265-1276.

Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

MeSH Terms: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/surgery , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/surgery , Tyrosine Kinase Inhibitors*/therapeutic use , Platinum Compounds*/therapeutic use , Antineoplastic Agents*/therapeutic use, Humans ; Carbazoles/therapeutic use ; Neoplasm Recurrence, Local/drug therapy ; Piperidines/therapeutic use ; Receptor Protein-Tyrosine Kinases ; Treatment Outcome ; Administration, Oral ; Administration, Intravenous

Perioperative Toripalimab Plus Chemotherapy for Patients With Resectable Non-Small Cell Lung Cancer: The Neotorch Randomized Clinical Trial.

Authors: Lu S Zhang W Wu L et al.

Corporate Authors: Lu S Zhang W Wu L et al.

Source: JAMA [JAMA] 2024 Jan 16; Vol. 331 (3), pp. 201-211.

Publication Type: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

MeSH Terms: Antibodies, Monoclonal, Humanized*/adverse effects , Antibodies, Monoclonal, Humanized*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/surgery , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Lung Neoplasms*/surgery , Antineoplastic Agents*/therapeutic use , Platinum Compounds*/administration & dosage , Platinum Compounds*/therapeutic use, Female ; Humans ; Male ; Middle Aged ; Pathologic Complete Response ; Combined Modality Therapy ; Aged

Expansion Microscopy Provides Nanoscale Insight into Nucleolar Reorganization and Nuclear Foci Formation during Nucleolar Stress.

Authors: Alley KR Wyatt KM Fries AC et al.

Source: ACS chemical biology [ACS Chem Biol] 2025 Jun 20; Vol. 20 (6), pp. 1232-1246. Date of Electronic Publication: 2025 May 20.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

MeSH Terms: Cell Nucleolus*/metabolism , Cell Nucleolus*/drug effects, Humans ; Dactinomycin/pharmacology ; HeLa Cells ; Platinum Compounds/chemistry ; Platinum Compounds/pharmacology ; Stress, Physiological ; Oxaliplatin/chemistry ; Oxaliplatin/pharmacology

Perioperative Nivolumab and Chemotherapy in Stage III Non-Small-Cell Lung Cancer.

Authors: Provencio M Nadal E González-Larriba JL et al.

Source: The New England journal of medicine [N Engl J Med] 2023 Aug 10; Vol. 389 (6), pp. 504-513. Date of Electronic Publication: 2023 Jun 28.

Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

MeSH Terms: Antineoplastic Combined Chemotherapy Protocols*/adverse effects , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/surgery , Lung Neoplasms*/drug therapy , Lung Neoplasms*/surgery , Nivolumab*/administration & dosage , Nivolumab*/adverse effects , Nivolumab*/therapeutic use , Platinum Compounds*/administration & dosage , Platinum Compounds*/adverse effects , Platinum Compounds*/therapeutic use, Humans ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Staging ; Survival Analysis ; Combined Modality Therapy

Synergistic strategies: histone deacetylase inhibitors and platinum-based drugs in cancer therapy.

Authors: Shirbhate E Singh V Kore R et al.

Source: Expert review of anticancer therapy [Expert Rev Anticancer Ther] 2025 Feb; Vol. 25 (2), pp. 121-141. Date of Electronic Publication: 2025 Jan 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101123358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8328 (Electronic) Linking ISSN: 14737140 NLM ISO Abbreviation: Expert Rev Anticancer Ther Subsets: MEDLINE

MeSH Terms: Histone Deacetylase Inhibitors*/administration & dosage , Histone Deacetylase Inhibitors*/pharmacology , Neoplasms*/drug therapy , Neoplasms*/pathology , Antineoplastic Combined Chemotherapy Protocols*/administration & dosage , Antineoplastic Combined Chemotherapy Protocols*/pharmacology , Antineoplastic Combined Chemotherapy Protocols*/adverse effects, Humans ; Drug Synergism ; Drug Resistance, Neoplasm ; Precision Medicine/methods ; Patient Selection ; Animals ; Platinum Compounds/administration & dosage ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacology

Atomic-precise Pt 2 Cu 4 cluster-based fluorescent sensor for rapid interleukin-6 detection.

Authors: Shao ZH Mo HL Zhao X et al.

Source: Analytical methods : advancing methods and applications [Anal Methods] 2023 Jul 06; Vol. 15 (26), pp. 3161-3164. Date of Electronic Publication: 2023 Jul 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: RSC Pub Country of Publication: England NLM ID: 101519733 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-9679 (Electronic) Linking ISSN: 17599660 NLM ISO Abbreviation: Anal Methods Subsets: MEDLINE

MeSH Terms: Platinum Compounds*/chemistry, Copper/chemistry ; Fluorescent Dyes/chemistry ; Interleukin-6/analysis

Experimental and molecular dynamics simulation study on thermal rectification in multilayer PtSe2.

Authors: Zhao, Haibo Yang, Xiao Shen, Yanan et al.

Source: Journal of Applied Physics; 11/7/2025, Vol. 138 Issue 17, p1-8, 8p

Subject Terms: TWO-dimensional materials (Nanotechnology), PLATINUM compounds, THERMOELECTRIC apparatus & appliances, SEMICONDUCTORS, MOLECULAR dynamics, TRANSISTORS

High expression of CETN2 is associated with platinum resistance and poor prognosis in epithelial ovarian cancer.

Authors: Qiu PY Deng XH Li L

Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2023 May; Vol. 25 (5), pp. 1340-1352. Date of Electronic Publication: 2022 Dec 17.

Publication Type: Journal Article

Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE

MeSH Terms: Carcinoma, Ovarian Epithelial*/drug therapy , Carcinoma, Ovarian Epithelial*/genetics , Carcinoma, Ovarian Epithelial*/metabolism , Drug Resistance, Neoplasm*/genetics , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/metabolism , Platinum Compounds*/pharmacology , Platinum Compounds*/therapeutic use , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use, Female ; Humans ; DNA Repair/genetics ; Prognosis

State of art in the chemistry of nucleoside-based Pt(II) complexes.

Authors: D'Errico S Falanga AP Greco F et al.

Source: Bioorganic chemistry [Bioorg Chem] 2023 Feb; Vol. 131, pp. 106325. Date of Electronic Publication: 2022 Dec 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH Terms: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Coordination Complexes*/pharmacology , Platinum Compounds*/chemistry , Platinum Compounds*/pharmacology, Cisplatin/chemistry ; Nucleosides/pharmacology ; Nucleotides