Search Results - "Pharmacogenomic Testing"

Multi-Gene Pharmacogenomic Testing in a Community-Based Setting Is Feasible and Reduces Total Healthcare Costs.

Authors: El Rouby N Allen JD Koep T et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Dec; Vol. 18 (12), pp. e70418.

Publication Type: Journal Article

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/economics , Pharmacogenomic Testing*/methods , Pharmacogenomic Testing*/statistics & numerical data , Health Care Costs*/statistics & numerical data , Community Health Services*/economics, Humans ; Female ; Male ; Aged ; United States ; Aged, 80 and over ; Polypharmacy ; Feasibility Studies ; Cost-Benefit Analysis ; Cost Savings/statistics & numerical data ; Medicare Part C/economics ; Medicare Part C/statistics & numerical data ; Retrospective Studies ; Primary Health Care/economics

Meta-analysis of Response and Remission Outcomes With a Weighted Multigene Pharmacogenomic Test for Adults With Depression.

Authors: Albers RE Dyer MP Kucera M et al.

Source: Journal of clinical psychopharmacology [J Clin Psychopharmacol] 2025 Nov-Dec 01; Vol. 45 (6), pp. 570-579. Date of Electronic Publication: 2025 Sep 03.

Publication Type: Journal Article; Meta-Analysis

Journal Info: Publisher: Williams And Wilkins Country of Publication: United States NLM ID: 8109496 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-712X (Electronic) Linking ISSN: 02710749 NLM ISO Abbreviation: J Clin Psychopharmacol Subsets: MEDLINE

MeSH Terms: Antidepressive Agents*/therapeutic use , Depressive Disorder, Major*/drug therapy , Depressive Disorder, Major*/genetics , Pharmacogenomic Testing*/methods, Adult ; Humans ; Remission Induction ; Treatment Outcome

Real-World Characterization of Psychiatric Pharmacogenomic Test Ordering and Clinical Relevance in Adults and Children.

Authors: Zhang L Tholkes AJ Jones KC et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Oct; Vol. 18 (10), pp. e70297.

Publication Type: Journal Article

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/statistics & numerical data , Pharmacogenomic Testing*/methods , Mental Disorders*/drug therapy , Mental Disorders*/genetics , Practice Patterns, Physicians'*/statistics & numerical data , Psychotropic Drugs*/therapeutic use, Humans ; Adult ; Male ; Female ; Child ; Electronic Health Records/statistics & numerical data ; Adolescent ; Middle Aged ; Young Adult ; Aged ; Child, Preschool ; Genotype ; Clinical Relevance

Progress in Pharmacogenomics Implementation in the United States: Barrier Erosion and Remaining Challenges.

Authors: Smith DM Douglas MP Aquilante CL et al.

Corporate Authors: Smith DM Douglas MP Aquilante CL et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Oct; Vol. 118 (4), pp. 778-789. Date of Electronic Publication: 2025 Jun 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: Pharmacogenetics*/economics , Pharmacogenetics*/trends , Pharmacogenetics*/methods , Pharmacogenetics*/legislation & jurisprudence , Pharmacogenomic Testing*/economics , Pharmacogenomic Testing*/methods, Humans ; United States ; Precision Medicine

The Clinical Pharmacogenetics Implementation Consortium's consensus-based framework for assigning allele function.

Authors: Tibben BM Gaedigk A Gong L et al.

Source: American journal of human genetics [Am J Hum Genet] 2025 Dec 04; Vol. 112 (12), pp. 2842-2859. Date of Electronic Publication: 2025 Oct 31.

Publication Type: Journal Article; Review

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

MeSH Terms: Alleles* , Pharmacogenetics*/methods , Pharmacogenetics*/standards , Pharmacogenomic Testing*/standards, Humans ; Consensus ; Haplotypes

Implementation of a pharmacist-guided pharmacogenomics dosing service at a rural NCI-designated comprehensive cancer center.

Authors: Green JK Hackett LJ Green DC et al.

Source: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2025 Dec; Vol. 31 (8), pp. 1264-1269. Date of Electronic Publication: 2024 Sep 04.

Publication Type: Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9511372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-092X (Electronic) Linking ISSN: 10781552 NLM ISO Abbreviation: J Oncol Pharm Pract Subsets: MEDLINE

MeSH Terms: Pharmacists*/organization & administration , Pharmacogenetics*/methods , Cancer Care Facilities*/organization & administration , Pharmacogenomic Testing*/methods , Neoplasms*/drug therapy , Neoplasms*/genetics , Antineoplastic Agents*/administration & dosage, Humans ; Male ; Female ; Middle Aged ; Aged ; Pilot Projects ; Professional Role ; National Cancer Institute (U.S.) ; Adult ; Lebanon ; Electronic Health Records ; Precision Medicine

Cost-Effectiveness of Pre-emptive DPYD Genotyping Compared to Standard of Care Among Patients Receiving Fluoropyrimidine-Based Anti-cancer Treatment in Australia.

Authors: Glewis S Fagery M Lingaratnam S et al.

Source: Clinical drug investigation [Clin Drug Investig] 2025 Dec; Vol. 45 (12), pp. 945-956. Date of Electronic Publication: 2025 Oct 27.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE

MeSH Terms: Neoplasms*/drug therapy , Neoplasms*/genetics , Neoplasms*/economics , Standard of Care*/economics , Dihydrouracil Dehydrogenase (NADP)*/genetics , Pharmacogenomic Testing*/economics, Humans ; Cost-Benefit Analysis ; Australia ; Quality-Adjusted Life Years ; Fluorouracil/adverse effects ; Fluorouracil/therapeutic use ; Genotype ; Male ; Female ; Pharmacogenetics/economics

Clinical implementation and outcome evaluation of dihydropyrimidine dehydrogenase (DPYD) pharmacogenomic testing for fluoropyrimidine dosing in a Canadian Provincial Healthcare center.

Authors: Wu F Lu S Zhang D et al.

Source: Clinical biochemistry [Clin Biochem] 2025 Dec; Vol. 140, pp. 111008. Date of Electronic Publication: 2025 Sep 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0133660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2933 (Electronic) Linking ISSN: 00099120 NLM ISO Abbreviation: Clin Biochem Subsets: MEDLINE

MeSH Terms: Dihydrouracil Dehydrogenase (NADP)*/genetics , Fluorouracil*/administration & dosage , Fluorouracil*/adverse effects , Fluorouracil*/analogs & derivatives , Capecitabine*/administration & dosage , Capecitabine*/adverse effects , Pharmacogenomic Testing*/methods , Antimetabolites, Antineoplastic*/administration & dosage , Antimetabolites, Antineoplastic*/adverse effects , Neoplasms*/drug therapy , Neoplasms*/genetics, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Canada ; Adult ; Genotype ; Dihydropyrimidine Dehydrogenase Deficiency/genetics ; Pyrimidines

CYP2D6 Pharmacogenetics in Nigerian Sickle Cell Disease: Phase 1 of Implementing Pharmacogenomics Testing for Effective Care and Treatment in Africa (iPROTECTA) program.

Authors: Adeagbo B Olarewaju O Orherhe O et al.

Corporate Authors: Adeagbo B Olarewaju O Orherhe O et al.

Source: Gates open research [Gates Open Res] 2025 Nov 10; Vol. 9, pp. 101. Date of Electronic Publication: 2025 Nov 10 (Print Publication: 2025).

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Bill and Melinda Gates Foundation Country of Publication: United States NLM ID: 101717821 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-4754 (Electronic) Linking ISSN: 25724754 NLM ISO Abbreviation: Gates Open Res Subsets: MEDLINE

MeSH Terms: Anemia, Sickle Cell*/genetics , Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/epidemiology , Cytochrome P-450 CYP2D6*/genetics , Analgesics, Opioid*/therapeutic use , Pharmacogenomic Testing*/methods, Humans ; Nigeria/epidemiology ; Female ; Male ; Adult ; Prospective Studies ; Adolescent ; Polymorphism, Single Nucleotide ; Young Adult ; Codeine/therapeutic use ; Pharmacogenetics/methods ; Genotype ; Tramadol/therapeutic use ; Middle Aged ; Phenotype ; Gene Frequency

Targeted adaptive sampling enables clinical pharmacogenomics testing and genome-wide genotyping.

Authors: Gan PHP Yeo HL Bin Hajis MI et al.

Source: Scientific reports [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39346. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/methods , Genotyping Techniques*/methods , Pharmacogenetics*/methods , Genome-Wide Association Study*/methods, Humans ; Genotype ; Cytochrome P-450 CYP2D6/genetics ; High-Throughput Nucleotide Sequencing/methods ; Polymorphism, Single Nucleotide ; Computational Biology/methods ; Haplotypes

Increasing statin prescribing through a pharmacogenomics-guided initiative.

Authors: Rennie C Roads M Bright B et al.

Source: Journal of the American Pharmacists Association : JAPhA [J Am Pharm Assoc (2003)] 2025 Nov-Dec; Vol. 65 (6), pp. 102898. Date of Electronic Publication: 2025 Aug 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101176252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1544-3450 (Electronic) Linking ISSN: 10865802 NLM ISO Abbreviation: J Am Pharm Assoc (2003) Subsets: MEDLINE

MeSH Terms: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Pharmacogenetics*/methods , Pharmacogenomic Testing*/methods , Practice Patterns, Physicians'*/statistics & numerical data, Humans ; Male ; Female ; Pharmacists/organization & administration ; United States Department of Veterans Affairs ; Middle Aged ; Aged ; Quality Improvement ; Veterans ; United States

Understanding clinician support preferences related to the use of pharmacogenomic results in electronic health records: A qualitative study in an academic health system.

Authors: Dreikorn EN Sacchi S Riden K et al.

Source: Journal of the American Pharmacists Association : JAPhA [J Am Pharm Assoc (2003)] 2025 Nov-Dec; Vol. 65 (6), pp. 102912. Date of Electronic Publication: 2025 Aug 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101176252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1544-3450 (Electronic) Linking ISSN: 10865802 NLM ISO Abbreviation: J Am Pharm Assoc (2003) Subsets: MEDLINE

MeSH Terms: Electronic Health Records* , Pharmacogenetics*/methods , Pharmacogenomic Testing*/methods, Humans ; Qualitative Research ; Pharmacists/psychology ; Attitude of Health Personnel ; Academic Medical Centers ; Precision Medicine/methods ; Pennsylvania ; Male ; Female ; Physicians/psychology ; Interviews as Topic ; Adult ; Middle Aged

Genome-wide screening of pharmacogenomic biomarkers in jordanian patients with genetic disorders.

Authors: Jarrar Y Hakooz N Hashem DA et al.

Source: The pharmacogenomics journal [Pharmacogenomics J] 2025 Oct 18; Vol. 25 (6), pp. 28. Date of Electronic Publication: 2025 Oct 18.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101083949 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-1150 (Electronic) Linking ISSN: 1470269X NLM ISO Abbreviation: Pharmacogenomics J Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/methods , Genetic Diseases, Inborn*/genetics , Genetic Diseases, Inborn*/drug therapy, Humans ; Jordan/epidemiology ; Male ; Female ; Adolescent ; Child ; Pharmacogenetics/methods ; Young Adult ; Whole Genome Sequencing ; Biomarkers ; Genome-Wide Association Study/methods ; Adult

An innovative model for pharmacogenomics critical results identification and intervention.

Authors: Uber R Hayduk VA Flango A et al.

Source: The pharmacogenomics journal [Pharmacogenomics J] 2025 Oct 02; Vol. 25 (5), pp. 25. Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101083949 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-1150 (Electronic) Linking ISSN: 1470269X NLM ISO Abbreviation: Pharmacogenomics J Subsets: MEDLINE

MeSH Terms: Pharmacogenetics*/methods , Pharmacogenomic Testing*/methods, Humans ; Precision Medicine/methods

Pharmacogenetic Implementation Studies-Lessons Learned From the PREPARE Study.

Authors: Guchelaar HJ van der Wouden CH Manson LEN et al.

Corporate Authors: Guchelaar HJ van der Wouden CH Manson LEN et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Oct; Vol. 118 (4), pp. 803-812. Date of Electronic Publication: 2025 Jun 24.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/methods , Drug-Related Side Effects and Adverse Reactions*/prevention & control , Drug-Related Side Effects and Adverse Reactions*/genetics , Pharmacogenetics*/methods, Humans ; Research Design ; Cross-Over Studies

Pharmacogenetic Testing - Evidence, Challenges, and Pathways to Adoption.

Authors: El Rouby N Johnson JA

Source: NEJM evidence [NEJM Evid] 2025 Oct; Vol. 4 (10), pp. EVIDra2400343. Date of Electronic Publication: 2025 Sep 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: NEJM Group, a division of the Massachusetts Medical Society Country of Publication: United States NLM ID: 9918317485806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2766-5526 (Electronic) Linking ISSN: 27665526 NLM ISO Abbreviation: NEJM Evid Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing* , Pharmacogenetics*, Humans

The prevalence of pharmacogenetic testing in the United States.

Authors: Czizik AM Burkett H Black JC et al.

Source: Pharmacogenetics and genomics [Pharmacogenet Genomics] 2025 Oct 01; Vol. 35 (8), pp. 221-225. Date of Electronic Publication: 2025 Sep 02.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101231005 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-6880 (Electronic) Linking ISSN: 17446872 NLM ISO Abbreviation: Pharmacogenet Genomics Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/statistics & numerical data , Pharmacogenetics*, Humans ; Female ; Adult ; United States ; Male ; Middle Aged ; Prevalence ; Young Adult ; Adolescent ; Aged ; Surveys and Questionnaires

Pharmacogenetic testing coverage by Canadian insurance providers.

Authors: Brubaker-Plitt R Bousman CA

Source: Pharmacogenetics and genomics [Pharmacogenet Genomics] 2026 Jan 01; Vol. 36 (1), pp. 18-22. Date of Electronic Publication: 2025 Oct 18.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101231005 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-6880 (Electronic) Linking ISSN: 17446872 NLM ISO Abbreviation: Pharmacogenet Genomics Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/economics , Insurance Coverage*/economics , Pharmacogenetics*/economics , Insurance, Health*/economics, Humans ; Canada ; Precision Medicine/economics

Implementation of mass pharmacogenetic testing: Dihydropyrimidine dehydrogenase testing prior to fluoropyrimidine treatment for patients.

Authors: Shaunak N Keen J Kim A et al.

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Sep; Vol. 91 (9), pp. 2534-2542. Date of Electronic Publication: 2025 Apr 27.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Dihydrouracil Dehydrogenase (NADP)*/genetics , Pharmacogenomic Testing*/methods , Pharmacogenomic Testing*/statistics & numerical data , Antimetabolites, Antineoplastic*/therapeutic use , Neoplasms*/drug therapy , Neoplasms*/genetics, Humans ; Surveys and Questionnaires ; Precision Medicine/methods ; Fluorouracil ; England ; Pharmacogenetics

Genotype-guided pharmacotherapy: the challenges of integrating pharmacogenomic testing into routine healthcare with a focus on experiences at a single site.

Authors: Cavallari LH Cicali EJ Norris M et al.

Source: Expert review of clinical pharmacology [Expert Rev Clin Pharmacol] 2025 Sep; Vol. 18 (9), pp. 655-667. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278296 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-2441 (Electronic) Linking ISSN: 17512433 NLM ISO Abbreviation: Expert Rev Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Pharmacogenomic Testing*/methods , Pharmacogenomic Testing*/economics , Pharmacogenetics*/methods, Humans ; Electronic Health Records ; Genotype ; Decision Support Systems, Clinical/organization & administration ; Pharmacists/organization & administration ; Precision Medicine/methods