Suchergebnisse - "Paracrine Communication"

MicroRNAs as key paracrine factors in stem cell therapy: Molecular mechanisms, therapeutic applications, and future perspectives.

Autoren: Zhong Y Liu X Ma L et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 05; Vol. 1008, pp. 178333. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , MicroRNAs*/metabolism , Paracrine Communication*/genetics , Stem Cell Transplantation*/methods , Stem Cells*/metabolism, Humans ; Animals ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/transplantation ; Regenerative Medicine/methods

Cx43 hemichannel-mediated paracrine involves in the promotion of MSCs on skin wound healing.

Autoren: Dou X Zhang Y Yang X et al.

Quelle: Stem cell research & therapy [Stem Cell Res Ther] 2025 Dec 03; Vol. 16 (1), pp. 672. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

MeSH-Schlagworte: Connexin 43*/metabolism , Connexin 43*/genetics , Wound Healing*/drug effects , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Paracrine Communication* , Skin*/metabolism , Skin*/injuries , Skin*/pathology, Animals ; Mice ; Culture Media, Conditioned/pharmacology ; Macrophages/metabolism ; Male ; Humans ; Mice, Inbred C57BL ; Fibroblasts/metabolism

Metabolic and Paracrine Heterogeneity of Pancreatic Glucagon-Secreting α-Cells.

Autoren: Dou H Miranda C Tolö J et al.

Quelle: Diabetes [Diabetes] 2025 Dec 01; Vol. 74 (12), pp. 2307-2321.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

MeSH-Schlagworte: Glucagon-Secreting Cells*/metabolism , Glucagon-Secreting Cells*/drug effects , Glucagon*/metabolism , Paracrine Communication*/physiology, Animals ; KATP Channels/metabolism ; KATP Channels/antagonists & inhibitors ; Mice ; Somatostatin/metabolism ; Action Potentials/drug effects ; Action Potentials/physiology ; Glucose/metabolism ; Glucose/pharmacology ; Amino Acids/pharmacology

Ultrasound-Stimulated BMSCs Promote Regenerative Healing in Refractory Foot Ulcer by Paracrine Effect.

Autoren: Tang Y Xu H He S et al.

Quelle: Ultrasound in medicine & biology [Ultrasound Med Biol] 2025 Dec; Vol. 51 (12), pp. 2292-2302. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 0410553 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-291X (Electronic) Linking ISSN: 03015629 NLM ISO Abbreviation: Ultrasound Med Biol Subsets: MEDLINE

MeSH-Schlagworte: Wound Healing*/physiology , Diabetic Foot*/therapy , Mesenchymal Stem Cell Transplantation*/methods , Mesenchymal Stem Cells*/physiology , Ultrasonic Therapy*/methods , Paracrine Communication* , Ultrasonic Waves*, Animals ; Rats, Sprague-Dawley ; Rats ; Male ; Disease Models, Animal

Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.

Autoren: Reinecke JB Jimenez Garcia L Saraf AJ et al.

Quelle: Cancer research [Cancer Res] 2025 Nov 14; Vol. 85 (22), pp. 4341-4358.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

MeSH-Schlagworte: Osteosarcoma*/pathology , Osteosarcoma*/metabolism , Osteosarcoma*/genetics , Lung Neoplasms*/secondary , Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Bone Neoplasms*/pathology , Bone Neoplasms*/metabolism , Bone Neoplasms*/genetics , Paracrine Communication*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Tumor Microenvironment ; Female ; Interleukin-1alpha/metabolism ; Xenograft Model Antitumor Assays

Myoblast paracrine factors induce catabolic remodelling in electrically stimulated myotubes.

Autoren: Lesinski MA Kamal MJ Parise G

Quelle: Scientific reports [Sci Rep] 2025 Nov 04; Vol. 15 (1), pp. 38537. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Muscle Fibers, Skeletal*/metabolism , Muscle Fibers, Skeletal*/cytology , Paracrine Communication* , Myoblasts*/metabolism , Myoblasts*/cytology, Animals ; Mice ; Electric Stimulation ; Cell Line ; Muscle, Skeletal/metabolism ; Cell Differentiation ; Signal Transduction

Gap Junctional Versus Paracrine Signaling in the Human Lens Epithelium: Analysis Based on Multicellular Ca²⁺ Imaging and Computational Modeling.

Autoren: Šterk M Thaler E Fajmut A et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Nov 03; Vol. 66 (14), pp. 39.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Gap Junctions*/metabolism , Gap Junctions*/physiology , Paracrine Communication*/physiology , Calcium Signaling*/physiology , Lens, Crystalline*/metabolism , Lens, Crystalline*/cytology , Calcium*/metabolism , Epithelial Cells*/metabolism, Humans ; Computer Simulation ; Carbenoxolone/pharmacology ; Adenosine Triphosphate/metabolism ; Cataract/metabolism ; Apyrase/pharmacology ; Aged

Depression- and exercise-associated stimuli exert contrasting effects on neural stem cell activity and paracrine signaling.

Autoren: Simão AL Sá Santos S Ferreira Moreira JA et al.

Quelle: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Nov; Vol. 1871 (8), pp. 167997. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

MeSH-Schlagworte: Neural Stem Cells*/metabolism , Neural Stem Cells*/pathology , Paracrine Communication* , Physical Conditioning, Animal* , Depression*/metabolism , Depression*/pathology, Animals ; Mice ; Neurogenesis ; Microglia/metabolism ; Male ; Mice, Inbred C57BL ; Cell Differentiation ; Cell Proliferation ; Mitochondria/metabolism ; Secretome/metabolism

Human Urine-Derived SIX2-Positive Renal Progenitor Cells Partially Improve Kidney Fibrosis by Paracrine Signaling.

Autoren: Kordes C Spitzhorn LS Bohndorf M et al.

Quelle: Stem cells and development [Stem Cells Dev] 2025 Nov; Vol. 34 (21-22), pp. 472-482. Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101197107 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8534 (Electronic) Linking ISSN: 15473287 NLM ISO Abbreviation: Stem Cells Dev Subsets: MEDLINE

MeSH-Schlagworte: Stem Cells*/metabolism , Stem Cells*/cytology , Kidney*/pathology , Kidney*/metabolism , Paracrine Communication* , Stem Cell Transplantation*, Humans ; Animals ; Female ; Fibrosis ; Mice ; Adult ; Reperfusion Injury/therapy ; Reperfusion Injury/pathology

Mesenchymal stromal cells modulate neutrophil phenotype via paracrine signals.

Autoren: Cherry L Popescu S Neculachi CA et al.

Quelle: Stem cell research & therapy [Stem Cell Res Ther] 2025 Oct 21; Vol. 16 (1), pp. 574. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

MeSH-Schlagworte: Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Neutrophils*/metabolism , Neutrophils*/cytology , Paracrine Communication* , Myocardial Infarction*/therapy , Myocardial Infarction*/pathology , Myocardial Infarction*/metabolism, Humans ; Animals ; Mice ; HL-60 Cells ; Phenotype ; Mesenchymal Stem Cell Transplantation ; Cell Differentiation ; Male ; Coculture Techniques

Selective Paracrine Modulation of Stromal Cells: Wharton's Jelly MSC Secretome Enhances Adipose-Derived MSC Functionality While Maintaining Dermal Fibroblast Quiescence.

Autoren: Stoyanova T Topalova L Kyurkchiev S et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 16; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Fibroblasts*/metabolism , Fibroblasts*/cytology , Secretome*/metabolism , Wharton Jelly*/cytology , Wharton Jelly*/metabolism , Paracrine Communication* , Adipose Tissue*/cytology , Adipose Tissue*/metabolism, Humans ; Cell Proliferation ; Cell Movement ; Animals ; Cells, Cultured ; Cell Adhesion ; Collagen/metabolism ; Rats ; Dermis/cytology

The modulation of SHED-induced macrophage polarization and plasticity through paracrine mediators.

Autoren: Mohammad-Hasani A Mohammadi S Saeidi M et al.

Quelle: Tissue & cell [Tissue Cell] 2025 Oct; Vol. 96, pp. 103038. Date of Electronic Publication: 2025 Jul 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH-Schlagworte: Macrophages*/cytology , Macrophages*/metabolism , Paracrine Communication* , Tooth, Deciduous*/cytology , Cell Plasticity* , Cell Polarity*, Humans ; Cytokines/metabolism ; Coculture Techniques ; THP-1 Cells ; Oxidative Stress

Advances in Photobiomodulation: Effects on Mesenchymal Stem Cells and their Paracrine Factors.

Autoren: Shi Z Chen S Cai W et al.

Quelle: Stem cell reviews and reports [Stem Cell Rev Rep] 2025 Oct; Vol. 21 (7), pp. 1918-1930. Date of Electronic Publication: 2025 Jul 10.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 101752767 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2629-3277 (Electronic) Linking ISSN: 26293277 NLM ISO Abbreviation: Stem Cell Rev Rep Subsets: MEDLINE

MeSH-Schlagworte: Mesenchymal Stem Cells*/radiation effects , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Paracrine Communication*/radiation effects , Low-Level Light Therapy*/methods, Humans ; Animals ; Tissue Engineering/methods ; Osteogenesis/radiation effects ; Cell Differentiation/radiation effects

Sense and sensitivity - decoding calcium signalling across cellular, autocrine, paracrine and endocrine pathways in plant resilience.

Autoren: Lederer S Liese A Lee J et al.

Quelle: Current opinion in plant biology [Curr Opin Plant Biol] 2025 Oct; Vol. 87, pp. 102782. Date of Electronic Publication: 2025 Aug 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Current Biology Ltd Country of Publication: England NLM ID: 100883395 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0356 (Electronic) Linking ISSN: 13695266 NLM ISO Abbreviation: Curr Opin Plant Biol Subsets: MEDLINE

MeSH-Schlagworte: Calcium Signaling*/physiology , Plant Immunity* , Autocrine Communication* , Paracrine Communication* , Plants*/metabolism , Plants*/immunology, Calcium/metabolism

Periostin enhances paracrine effect of adipose-derived stem cells on chondrocyte proliferation, adhesion and migration.

Autoren: Lu R Hou Y Wang X et al.

Quelle: Tissue & cell [Tissue Cell] 2025 Oct; Vol. 96, pp. 102979. Date of Electronic Publication: 2025 May 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH-Schlagworte: Chondrocytes*/cytology , Chondrocytes*/metabolism , Cell Movement* , Adipose Tissue*/cytology , Adipose Tissue*/metabolism , Cell Adhesion Molecules*/metabolism , Paracrine Communication* , Stem Cells*/cytology , Stem Cells*/metabolism, Animals ; Cell Proliferation ; Mice ; Cell Adhesion ; Apoptosis ; Signal Transduction ; Periostin

Lactate Promotes the Second Cell Fate Decision in Blastocysts by Prompting Primitive Endoderm Formation Through an Intercellular Positive Feedback Loop That Couples Paracrine FGF Signalling.

Autoren: Hu X Tang Y Zhao W et al.

Quelle: Cell proliferation [Cell Prolif] 2025 Oct; Vol. 58 (10), pp. e70088. Date of Electronic Publication: 2025 Jun 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2184 (Electronic) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif Subsets: MEDLINE

MeSH-Schlagworte: Endoderm*/metabolism , Endoderm*/cytology , Lactic Acid*/metabolism , Lactic Acid*/pharmacology , Blastocyst*/metabolism , Blastocyst*/cytology , Fibroblast Growth Factors*/metabolism , Paracrine Communication*/drug effects, Animals ; Cell Differentiation/drug effects ; Mice ; Signal Transduction ; Embryonic Development ; Feedback, Physiological ; Cell Lineage ; Female

New Perspectives on Paracrine IL-18 Signaling in the Intestinal Epithelium.

Autoren: Winsor NJ Ranger A Singh O et al.

Quelle: DNA and cell biology [DNA Cell Biol] 2025 Oct; Vol. 44 (10), pp. 533-536. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article; Review; Editorial

Info zur Zeitschrift: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7430 (Electronic) Linking ISSN: 10445498 NLM ISO Abbreviation: DNA Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Interleukin-18*/metabolism , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/immunology , Intestinal Mucosa*/cytology , Signal Transduction* , Paracrine Communication*, Animals ; Humans ; Mice ; Inflammasomes/metabolism

Spatial transcriptomics exploration of the primary neuroblastoma microenvironment in archived FFPE samples unveils novel paracrine interactions.

Autoren: Siaw JT Merseburger P Borenäs M et al.

Quelle: The Journal of pathology [J Pathol] 2025 Oct; Vol. 267 (2), pp. 181-195. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE

MeSH-Schlagworte: Tumor Microenvironment*/genetics , Neuroblastoma*/genetics , Neuroblastoma*/pathology , Neuroblastoma*/metabolism , Transcriptome* , Paracrine Communication*/genetics , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/metabolism, Humans ; Paraffin Embedding ; Gene Expression Profiling ; Single-Cell Analysis ; Gene Expression Regulation, Neoplastic ; Formaldehyde ; Male

Senescent-like border-associated macrophages regulate cognitive aging via migrasome-mediated induction of paracrine senescence in microglia.

Autoren: Hu M Kang X Liu Z et al.

Quelle: Nature aging [Nat Aging] 2025 Oct; Vol. 5 (10), pp. 2039-2054. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/metabolism , Microglia*/physiology , Cellular Senescence*/physiology , Paracrine Communication*/physiology , Macrophages*/physiology , Macrophages*/metabolism , Cognitive Aging*/physiology , Aging*, Animals ; Mice ; Apoptosis ; Mice, Inbred C57BL ; Cell Movement ; Male ; Amyloid beta-Peptides/metabolism ; Brain/pathology ; Humans

Paracrine IGFBP3 spatially coordinates IGF signaling to induce myocardial regeneration in mice.

Autoren: Ali SR Nguyen NUN Elhelaly W et al.

Quelle: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2025 Oct; Vol. 207, pp. 93-106. Date of Electronic Publication: 2025 Aug 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

MeSH-Schlagworte: Insulin-Like Growth Factor Binding Protein 3*/metabolism , Insulin-Like Growth Factor Binding Protein 3*/genetics , Regeneration*/genetics , Paracrine Communication* , Signal Transduction* , Myocardium*/metabolism , Myocardium*/pathology , Insulin-Like Growth Factor II*/metabolism , Heart*/physiology, Animals ; Myocytes, Cardiac/metabolism ; Mice ; Animals, Newborn ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Myocardial Infarction/genetics ; Mitosis