Výsledky vyhľadávania - "Pancreatic Neoplasms pathology"

Single-Cell Lipidomics by LC-MS Interlaboratory Study Reveals the Impact of X-ray Irradiation on a Pancreatic Cancer Cell Line and Its Bystanders

Autori: Kyle D. G. Saunders Johanna von Gerichten Rahul Deshpande a ďalší

Zdroj: Anal Chem
Saunders, K D G, von Gerichten, J, Deshpande, R, Spick, M, Bird, S, Schettino, G, Bolland, H, Whetton, A, Velliou, E & Bailey, M J 2025, 'Single-Cell Lipidomics by LC-MS Interlaboratory Study Reveals the Impact of X-ray Irradiation on a Pancreatic Cancer Cell Line and Its Bystanders', Analytical Chemistry, vol. 97, no. 25, pp. 13532-13541. https://doi.org/10.1021/acs.analchem.5c02010

Predmety: Lipidomics/methods, Lipids/analysis, Pancreatic Neoplasms/pathology, X-Rays, Cell Line, Tumor, Liquid Chromatography-Mass Spectrometry, Single-Cell Analysis/methods, Humans, Mass Spectrometry, Article, Chromatography, Liquid

Popis súboru: application/pdf

Prístupová URL adresa: https://kclpure.kcl.ac.uk/ws/files/349691271/saunders-et-al-2025-single-cell-lipidomics-by-lc-ms-interlaboratory-study-reveals-the-impact-of-x-ray-irradiation-on-a.pdf

Cancer du pancréas en 2025 : prise en charge multidisciplinaire

Autori: Brito, Rita Mack, Sahar Bornand, Aurélie a ďalší

Zdroj: Revue Médicale Suisse. 21:1010-1015

Predmety: Pancreatic Neoplasms / diagnosis, Minimally Invasive Surgical Procedures / methods, 616.0757, Pancreatic Neoplasms / epidemiology, 616.07, Prognosis, Combined Modality Therapy, Switzerland / epidemiology, Pancreatic Neoplasms / therapy, Survival Rate, Pancreatic Neoplasms / pathology, Humans

Popis súboru: application/pdf

Prístupová URL adresa: https://archive-ouverte.unige.ch/unige:186719
https://doi.org/10.53738/revmed.2025.21.918.47207

Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas

Autori: Chen, Jing Sobecki, Michal Krzywinska, Ewelina a ďalší

Prispievatelia: Chen, Jing Sobecki, Michal Krzywinska, Ewelina a ďalší

Zdroj: EMBO Mol Med
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3033-3056 (2024)

Predmety: Cancer-Associated Fibroblasts Immunology, Medicine (General), Adenocarcinoma Immunology, 10017 Institute of Anatomy, Cancer-Associated Fibroblasts Pathology, 10184 Institute of Veterinary Pathology, ADAM12 Protein Metabolism, Pancreatic Neoplasms Prevention & Control, ADAM12 Protein, 610 Medicine & health, QH426-470, CD8-Positive T-Lymphocytes, Adenocarcinoma, 10263 Institute of Experimental Immunology, Cancer Vaccines, Mice, CD8-Positive T-Lymphocytes Immunology, R5-920, Cancer-Associated Fibroblasts, Report, Carcinoma, Pancreatic Ductal Pathology, Genetics, Mice Inbred C57BL, Adenocarcinoma Pathology, Animals, Humans, Cancer Vaccines Immunology, Pancreatic Adenocarcinoma, Cancer Vaccines Administration & Dosage, Cancer-Associated Fibroblasts Metabolism, Disease Models Animal, Vaccination, Fibrosis, Pancreatic Neoplasms, Mice, Inbred C57BL, Disease Models, Animal, Pancreatic Neoplasms Immunology, 1313 Molecular Medicine, 11401 Comprehensive Cancer Center Zurich, Pancreatic Neoplasms Pathology, Carcinoma Pancreatic Ductal Therapy, Adenocarcinoma Therapy, 570 Life sciences, biology, Immunotherapy, Carcinoma Pancreatic Ductal Immunology, Carcinoma, Pancreatic Ductal

Popis súboru: application/pdf; chen_et_al_2024_fibrolytic_vaccination_against_adam12_reduces_desmoplasia_in_preclinical_pancreatic_adenocarcinomas.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39478152
https://doaj.org/article/32a6bfacd9884de49c5ed19adffba64c
https://phaidra.vetmeduni.ac.at/o:3794
https://doi.org/10.1038/s44321-024-00157-4

Efficacy and Safety of the Anti-IL1RAP Antibody Nadunolimab (CAN04) in Combination with Gemcitabine and Nab-Paclitaxel in Patients with Advanced/Metastatic Pancreatic Cancer

Autori: Van Cutsem, Eric Collignon, Joëlle Eefsen, Rikke L a ďalší

Zdroj: Clin Cancer Res

Predmety: Male, Pancreatic Neoplasms/pathology, Oncologie, Carcinoma, Pancreatic Ductal/drug therapy, Deoxycytidine, ACTIVATION, Deoxycytidine/analogs & derivatives, Pancreatic Neoplasms/drug therapy, Antineoplastic Combined Chemotherapy Protocols, Paclitaxel/adverse effects, Human health sciences, Neoplasm Metastasis, Aged, 80 and over, CHEMORESISTANCE, Carcinoma, Pancreatic Ductal/immunology, Medicine (all), Middle Aged, Treatment Outcome, Oncology, Antibodies, Monoclonal, Humanized/adverse effects, Female, Pancreatic Neoplasms/immunology, Life Sciences & Biomedicine, Albumins/administration & dosage, Antibodies, Monoclonal, Humanized/administration & dosage, Carcinoma, Pancreatic Ductal, Adult, Paclitaxel, Clinical Trials: Targeted Therapy, Carcinoma, Pancreatic Ductal/pathology, Antibodies, Monoclonal, Humanized, Sciences de la santé humaine, POOR-PROGNOSIS, Paclitaxel/administration & dosage, 3211 Oncology and carcinogenesis, Albumins, Biomarkers, Tumor, Pancreatic Neoplasms/mortality, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Deoxycytidine/administration & dosage, Aged, Albumins/adverse effects, Science & Technology, Antineoplastic Combined Chemotherapy Protocols/adverse effects, IL1RAP protein, human, 3202 Clinical sciences, 130-nm albumin-bound paclitaxel, Gemcitabine, Pancreatic Neoplasms, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Interleukin-1 Receptor Accessory Protein, Deoxycytidine/therapeutic use

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39385434
https://lirias.kuleuven.be/handle/20.500.12942/769085
https://doi.org/10.1158/1078-0432.ccr-24-0645
https://hdl.handle.net/2268/333840
https://doi.org/10.1158/1078-0432.CCR-24-0645

Rapid Evolution of Metastases in Patients with Treated G3 Neuroendocrine Tumors Associated with NEC-Like Transformation and TP53 Mutation

Autori: Atsuko Kasajima Nicole Pfarr Eva-Maria Mayr a ďalší

Zdroj: Endocr Pathol

Predmety: Male, Adult, Female [MeSH], Pancreatic Neoplasms/genetics [MeSH], Disease Progression [MeSH], Mutation [MeSH], Aged [MeSH], Pancreatic Neoplasms/pathology [MeSH], Adult [MeSH], Humans [MeSH], Neoplasm Metastasis [MeSH], Longitudinal Studies [MeSH], Progression, Middle Aged [MeSH], Tumor Suppressor Protein p53/genetics [MeSH], Transformation, Neuroendocrine tumors, Male [MeSH], NEC-like NET G3, Neuroendocrine Tumors/pathology [MeSH], Research, Carcinoma, Neuroendocrine/pathology [MeSH], Carcinoma, Neuroendocrine/genetics [MeSH], Neuroendocrine Tumors/genetics [MeSH], Middle Aged, ddc, Carcinoma, Neuroendocrine, Pancreatic Neoplasms, Neuroendocrine Tumors, Mutation, Disease Progression, Humans, Female, Longitudinal Studies, Tumor Suppressor Protein p53, Neoplasm Metastasis, Aged

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39382626
https://repository.publisso.de/resource/frl:6503559
https://mediatum.ub.tum.de/doc/1770587/document.pdf

Textural heterogeneity of liver lesions in CT imaging - comparison of colorectal and pancreatic metastases

Autori: Friedrich L. Pietsch Florian Haag Isabelle Ayx a ďalší

Zdroj: Abdom Radiol (NY)

Predmety: Male, Adult, Aged, 80 and over, 0301 basic medicine, Liver Neoplasms, Contrast Media, Middle Aged, Pancreatic Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Female [MeSH], Pancreas, Computed tomography, Aged, 80 and over [MeSH], Aged [MeSH], Liver Neoplasms/diagnostic imaging [MeSH], Pancreatic Neoplasms/pathology [MeSH], Colorectum, Adult [MeSH], Hepatobiliary, Humans [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Tomography, X-Ray Computed/methods [MeSH], Radiographic Image Interpretation, Computer-Assisted/methods [MeSH], Pancreatic Neoplasms/diagnostic imaging [MeSH], Contrast Media [MeSH], Radiomics, Tumoral Heterogeneity, Male [MeSH], Tumor/Oncology, Liver Neoplasms/secondary [MeSH], Colorectal Neoplasms/pathology [MeSH], Colorectal Neoplasms/diagnostic imaging [MeSH], Humans, Radiographic Image Interpretation, Computer-Assisted, Female, Colorectal Neoplasms, Tomography, X-Ray Computed, Retrospective Studies, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39115682
https://repository.publisso.de/resource/frl:6502305

BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells

Autori: Bilal Alashkar Alhamwe Viviane Ponath Fahd Alhamdan a ďalší

Zdroj: Cell Mol Immunol

Predmety: 0301 basic medicine, 0303 health sciences, Cell Line, Tumor [MeSH], Disease Progression [MeSH], Mice, Inbred C57BL [MeSH], Pancreatic Neoplasms/pathology [MeSH], Mast Cells/immunology [MeSH], BAG6, Mast Cells/metabolism [MeSH], Interleukin-33/genetics [MeSH], Extracellular Vesicles/metabolism [MeSH], Pancreatic cancer, Carcinoma, Pancreatic Ductal/immunology [MeSH], Cell Proliferation [MeSH], Interleukin-33/metabolism [MeSH], Humans [MeSH], Animals [MeSH], Mast cells, Carcinoma, Pancreatic Ductal/genetics [MeSH], Pancreatic Neoplasms/immunology [MeSH], Mice [MeSH], Article, Carcinoma, Pancreatic Ductal/pathology [MeSH], 631/250/251, EVs, article, 631/67/580, Tumor Microenvironment [MeSH], Interleukin-33, Mice, Inbred C57BL, Pancreatic Neoplasms, Mice, Extracellular Vesicles, 03 medical and health sciences, Cell Line, Tumor, Disease Progression, Tumor Microenvironment, Animals, Humans, Mast Cells, Carcinoma, Pancreatic Ductal, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38942797
https://repository.publisso.de/resource/frl:6506245

Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions

Autori: Patel, Sameer H. Wilson, Gregory C. Wu, Yuqing a ďalší

Zdroj: J Mol Med (Berl)

Predmety: 0301 basic medicine, 0303 health sciences, Kv1.3 Potassium Channel, Cell Death, Medizin, Mitochondria, Cell Line, Tumor [MeSH], Proto-Oncogene Proteins p21(ras)/metabolism [MeSH], Pancreatic Neoplasms/pathology [MeSH], Proto-Oncogene Proteins p21(ras)/genetics [MeSH], Original Article, Cell Death/drug effects [MeSH], Kv1.3, Kv1.3 Potassium Channel/antagonists, Carcinoma, Pancreatic Ductal/metabolism [MeSH], Pancreatic Neoplasms/genetics [MeSH], Mitochondria/metabolism [MeSH], Humans [MeSH], Kv1.3 Potassium Channel/genetics [MeSH], Kv1.3 Potassium Channel/metabolism [MeSH], Animals [MeSH], Pancreatic Neoplasms/drug therapy [MeSH], Cytochrome C, Carcinoma, Pancreatic Ductal/genetics [MeSH], Sphingosine/analogs, Carcinoma, Pancreatic Ductal/drug therapy [MeSH], Mice [MeSH], Pancreas cancer, Sphingosine/metabolism [MeSH], Carcinoma, Pancreatic Ductal/pathology [MeSH], Mitochondria/drug effects [MeSH], Pancreatic Neoplasms/metabolism [MeSH], Sphingosine, 3. Good health, Pancreatic Neoplasms, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, Cell Line, Tumor, Humans, Animals, Carcinoma, Pancreatic Ductal

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38780771
https://hdl.handle.net/11577/3515924
https://doi.org/10.1007/s00109-024-02456-2
https://repository.publisso.de/resource/frl:6518160
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85193940138
https://www.ncbi.nlm.nih.gov/pubmed/38780771
https://doi.org/10.1007/s00109-024-02456-2

Nanoformulation of dasatinib cannot overcome therapy resistance of pancreatic cancer cells with low LYN kinase expression

Autori: Marilyn Kaul Ahmed Y. Sanin Wenjie Shi a ďalší

Zdroj: Pharmacol Rep

Predmety: 0301 basic medicine, 0303 health sciences, Dasatinib, Metal Nanoparticles, Antineoplastic Agents, Article, Pancreatic Neoplasms, 03 medical and health sciences, src-Family Kinases, Drug Resistance, Neoplasm, Cell Line, Tumor, Humans, Gold, Pancreatic Neoplasms/genetics [MeSH], Cell Line, Tumor [MeSH], Dasatinib/pharmacology [MeSH], Gold/chemistry [MeSH], Drug Resistance, Neoplasm/drug effects [MeSH], Pancreatic Neoplasms/pathology [MeSH], Protein Kinase Inhibitors/pharmacology [MeSH], Humans [MeSH], Gold nanoparticles, Nanomedicine, Antineoplastic Agents/pharmacology [MeSH], LYN, Pancreatic Neoplasms/drug therapy [MeSH], Metal Nanoparticles/administration, Carcinoma, Pancreatic Ductal/drug therapy [MeSH], Metal Nanoparticles/chemistry [MeSH], Carcinoma, Pancreatic Ductal/pathology [MeSH], Dasatinib/administration, Cell Proliferation/drug effects [MeSH], src-Family Kinases/metabolism [MeSH], Pancreatic cancer, Protein Kinase Inhibitors, Carcinoma, Pancreatic Ductal, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38739359
https://repository.publisso.de/resource/frl:6519233

REDISCOVER guidelines for borderline-resectable and locally advanced pancreatic cancer: management algorithm, unanswered questions, and future perspectives: management algorithm, unanswered questions, and future perspectives

Autori: Boggi, Ugo Kauffmann, Emanuele F. Napoli, Niccolò a ďalší

Zdroj: Updates Surg

Predmety: REDISCOVER guidelines, Borderline resectable pancreatic cancer, Locally advanced pancreatic cancer, Pancreatic cancer, Pancreatic ductal adenocarcinoma, REDISCOVER registry, Algorithms [MeSH], Systematic Reviews as Topic [MeSH], Pancreatectomy/methods [MeSH], Pancreatic Neoplasms/pathology [MeSH], Humans [MeSH], Consensus Conference, Perioperative Care/methods [MeSH], Neoadjuvant Therapy [MeSH], Pancreatic Neoplasms/therapy [MeSH], Carcinoma, Pancreatic Ductal/pathology [MeSH], Carcinoma, Pancreatic Ductal/therapy [MeSH], Neoadjuvant Therapy, Perioperative Care, 3. Good health, Pancreatic Neoplasms, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Humans, Algorithms, Carcinoma, Pancreatic Ductal, Systematic Reviews as Topic

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38684573
https://link.springer.com/article/10.1007/s13304-024-01860-0
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11564/842552
https://hdl.handle.net/20.500.11768/170696
https://link.springer.com/article/10.1007/s13304-024-01860-0
https://doi.org/10.1007/s13304-024-01860-0
https://pure.amsterdamumc.nl/en/publications/dc909c8d-f162-4064-b61e-ab82c5fa0df1
https://doi.org/10.1007/s13304-024-01860-0
https://ora.ox.ac.uk/objects/uuid:4ae4b539-a27a-4a96-854e-7699aef9618f
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/2434/1078680
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11577/3514323
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11383/2191869
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11379/615728
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11380/1367533
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11573/1746388
https://doi.org/10.1007/s13304-024-01860-0
https://repository.publisso.de/resource/frl:6518220
https://hdl.handle.net/11568/1248407
https://link.springer.com/article/10.1007/s13304-024-01860-0
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11697/257982
https://doi.org/10.1007/s13304-024-01860-0
https://link.springer.com/article/10.1007/s13304-024-01860-0
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/11585/1008456
https://hdl.handle.net/20.500.11769/604589
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/2158/1404714
https://link.springer.com/article/10.1007/s13304-024-01860-0
https://doi.org/10.1007/s13304-024-01860-0
https://hdl.handle.net/2318/2035042
https://doi.org/10.1007/s13304-024-01860-0

Differences in Lymph Node Metastases Patterns Among Non-pancreatic Periampullary Cancers and Histologic Subtypes: An International Multicenter Retrospective Cohort Study and Systematic Review

Autori: Uijterwijk, Bas A. Lemmers, Daniël H. Fusai, Giuseppe Kito a ďalší

Prispievatelia: Uijterwijk, Bas A. Lemmers, Daniël H. Fusai, Giuseppe Kito a ďalší

Zdroj: Ann Surg Oncol

Predmety: Male, Ampulla of Vater, CARCINOMA, Common Bile Duct Neoplasms, Adenocarcinoma, Pancreaticoduodenectomy, Cholangiocarcinoma, 03 medical and health sciences, PROGNOSTIC-FACTORS, 0302 clinical medicine, Duodenal Neoplasms, Humans, Retrospective Studies, Aged, Science & Technology, pancreatoduodenectomy, ampullary adenocarcinoma, PANCREATICOBILIARY, STATEMENT, Kirurgi, Pancreatic Tumors, DISTAL CHOLANGIOCARCINOMA, Middle Aged, Prognosis, 3. Good health, Pancreatic Neoplasms, Oncology, Bile Duct Neoplasms, Lymphatic Metastasis, PANCREATICODUODENECTOMY, SURVIVAL, Lymph Node Excision, Surgery, Female, Lymph Nodes, AMPULLA, Life Sciences & Biomedicine, Lymph Nodes/pathology [MeSH], Ampulla of Vater/pathology [MeSH], Aged [MeSH], Pancreatic Neoplasms/pathology [MeSH], Common Bile Duct Neoplasms/pathology [MeSH], Common Bile Duct Neoplasms/surgery [MeSH], Ampulla of Vater/surgery [MeSH], Duodenal Neoplasms/pathology [MeSH], Lymphatic Metastasis [MeSH], Adenocarcinoma/secondary [MeSH], Male [MeSH], Adenocarcinoma/pathology [MeSH], Bile Duct Neoplasms/surgery [MeSH], Carcinoma, Pancreatic Ductal/surgery [MeSH], Duodenal Neoplasms/surgery [MeSH], Pancreaticoduodenectomy [MeSH], Lymph Nodes/surgery [MeSH], Pancreatic Neoplasms/surgery [MeSH], Cholangiocarcinoma/surgery [MeSH], Female [MeSH], Follow-Up Studies [MeSH], Humans [MeSH], Retrospective Studies [MeSH], Bile Duct Neoplasms/pathology [MeSH], Middle Aged [MeSH], Carcinoma, Pancreatic Ductal/secondary [MeSH], Lymph Node Excision [MeSH], Carcinoma, Pancreatic Ductal/pathology [MeSH], Cholangiocarcinoma/pathology [MeSH], Prognosis [MeSH], Adenocarcinoma/surgery [MeSH], Follow-Up Studies, Carcinoma, Pancreatic Ductal

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38602578
https://ddd.uab.cat/record/306320
https://repository.publisso.de/resource/frl:6494004
https://hdl.handle.net/11568/1248428
https://doi.org/10.1245/s10434-024-15213-z
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-202921

Long-Term Oncologic Outcome following Duodenum-Preserving Pancreatic Head Resection for Benign Tumors, Cystic Neoplasms, and Neuroendocrine Tumors: Systematic Review and Meta-analysis

Autori: Beger, Hans G. Mayer, Benjamin Poch, Bertram

Zdroj: Ann Surg Oncol

Predmety: Pancreatoduodenectomy, Pancreaticoduodenectomy/adverse effects [MeSH], Duodenum-preserving pancreatic head resection, Neuroendocrine neoplasm of the pancreas, Pancreatectomy/methods [MeSH], Pancreatic Neoplasms/pathology [MeSH], Cystic neoplasm, Humans [MeSH], Pancreatic Tumors, Duodenum/surgery [MeSH], Organ Sparing Treatments/methods [MeSH], Neuroendocrine Tumors/surgery [MeSH], Benign pancreatic head tumors, Duodenum/pathology [MeSH], Neuroendocrine Tumors/pathology [MeSH], Pancreaticoduodenectomy/methods [MeSH], Prognosis [MeSH], Postoperative Complications/etiology [MeSH], Periampullary neoplasms, Pancreatic Cyst/pathology [MeSH], Pancreatic Neoplasms/surgery [MeSH], Pancreatic Cyst/surgery [MeSH], Duodenum, Prognosis, Pancreaticoduodenectomy, Pancreatic Neoplasms, Neuroendocrine Tumors, 03 medical and health sciences, Postoperative Complications, Pancreatectomy, 0302 clinical medicine, Humans, Pancreatic Cyst, Organ Sparing Treatments

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38578553
http://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-56817-0
https://doi.org/10.18725/OPARU-56742
https://repository.publisso.de/resource/frl:6517756

Identification of tumour regression in neoadjuvantly treated pancreatic cancer is based on divergent and nonspecific criteria

Autori: Holm, Maia Blomhoff Lenggenhager, Daniela Detlefsen, Sönke a ďalší

Prispievatelia: Holm, Maia Blomhoff Lenggenhager, Daniela Detlefsen, Sönke a ďalší

Zdroj: Histopathology. 85:171-181

Predmety: therapeutic effect, Male, Observer Variation, Pancreatic Neoplasms/pathology, pancreatic cancer, 610 Medicine & health, Middle Aged, 2722 Histology, observer variation, Neoadjuvant Therapy, 3. Good health, 2734 Pathology and Forensic Medicine, Pancreatic Neoplasms, 03 medical and health sciences, 0302 clinical medicine, 10049 Institute of Pathology and Molecular Pathology, Antineoplastic Combined Chemotherapy Protocols, Humans, pathology, Female, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Neoplasm Grading, neoadjuvant chemotherapy, Aged

Popis súboru: Histopathology___2024___Holm.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38571446
https://www.zora.uzh.ch/id/eprint/266196/
https://doi.org/10.5167/uzh-266196

Prämaligne, zystische Neoplasien und neuroendokrine Tumoren des Pankreaskopfes – Ist die Kausch-Whipple-Resektion eine adäquate Therapie?

Autori: Beger, Hans G.

Zdroj: Chirurgie (Heidelb)

Predmety: Neuroendocrine tumor, Pancreatoduodenectomy, Duodenum-preserving resection of the pancreatic head, Neuroendokrine Tumore, Cystic neoplasm, Übersichten, Precancerous Conditions/surgery [MeSH], Pancreatic Neoplasms/pathology [MeSH], Postoperative Complications/epidemiology [MeSH], Pankreatoduodenektomie, Pancreaticoduodenectomy/mortality [MeSH], Precancerous Conditions/pathology [MeSH], Neuroendocrine Tumors/pathology [MeSH], Postoperative Complications/etiology [MeSH], Pancreatic Neoplasms/mortality [MeSH], Pancreatic Neoplasms/surgery [MeSH], Pancreaticoduodenectomy/adverse effects [MeSH], Tumor enucleation, Zystische Neoplasie, Humans [MeSH], Duodenumerhaltende Resektion des Pankreaskopfes, Neuroendocrine Tumors/surgery [MeSH], Tumorenukleation, Neuroendocrine Tumors/mortality [MeSH], Pancreaticoduodenectomy/methods [MeSH], Pancreatic Cyst/pathology [MeSH], Pancreatic Cyst/surgery [MeSH]

Popis súboru: application/pdf

Prístupová URL adresa: http://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-56787-5
https://doi.org/10.18725/OPARU-56712
https://repository.publisso.de/resource/frl:6523806

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Autori: Jain, Aakriti Heremans, Isaac Rademaker, Gilles a ďalší

Prispievatelia: Jain, Aakriti Heremans, Isaac Rademaker, Gilles a ďalší

Zdroj: Science, Vol. 387, no.6741, p. eadq8331 (2025)

Predmety: Proteomics, Pancreatic Neoplasms/pathology, Carcinoma, Pancreatic Ductal/genetics, Carcinoma, Pancreatic Ductal/pathology, Lysosomes/metabolism, Biochimie, biophysique & biologie moléculaire, Leucyl Aminopeptidase/metabolism, Leucyl Aminopeptidase, Mice, Protein Domains, Leucine, Cell Line, Tumor, Leucine/metabolism, Humans, Animals, Membrane Proteins/genetics, Pancreatic Neoplasms/metabolism, Membrane Proteins, Leucyl Aminopeptidase/genetics, Pancreatic Neoplasms/genetics, Life sciences, Endocytosis, Pancreatic Neoplasms, Proteolysis, Sciences du vivant, Pinocytosis, Membrane Proteins/metabolism, Lysosomes, Hydrophobic and Hydrophilic Interactions, Carcinoma, Pancreatic Ductal/metabolism, Biochemistry, biophysics & molecular biology, Carcinoma, Pancreatic Ductal

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40146846
https://hdl.handle.net/2078.1/302769

Local Inflammation Precedes Diaphragm Wasting and Fibrotic Remodelling in a Mouse Model of Pancreatic Cancer

Autori: Daria Neyroud Andrew C. D'Lugos Enrique J. Trevino a ďalší

Zdroj: J Cachexia Sarcopenia Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 16, Iss 1, Pp n/a-n/a (2025)
Journal of cachexia, sarcopenia and muscle, vol. 16, no. 1, pp. e13668

Predmety: muscle atrophy, muscle fibrosis, Inflammation, Cachexia, pancreatic cancer, QM1-695, Diaphragm, Animals, Mice, Diaphragm/pathology, Diaphragm/metabolism, Diaphragm/physiopathology, Pancreatic Neoplasms/pathology, Pancreatic Neoplasms/complications, Disease Models, Animal, Fibrosis, Cachexia/etiology, Cachexia/pathology, Cachexia/metabolism, Humans, cancer cachexia, inflammatory response, Diseases of the musculoskeletal system, Pancreatic Neoplasms, RC925-935, Human anatomy, Original Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39810606
https://doaj.org/article/5edaf3db8e614c4b8dc77c4e06bdd541
https://serval.unil.ch/notice/serval:BIB_DA569A51F3FB
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DA569A51F3FB5
https://serval.unil.ch/resource/serval:BIB_DA569A51F3FB.P001/REF.pdf

Adjuvant Gemcitabine Versus Neoadjuvant/Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: The Randomized Multicenter Phase II NEPAFOX Trial

Autori: Goetze, Thorsten O. Reichart, Alexander Bankstahl, Ulli S. a ďalší

Zdroj: Ann Surg Oncol

Predmety: Male, Adult, Leucovorin, Pancreatic Tumors, Middle Aged, Irinotecan, Prognosis, Deoxycytidine, Gemcitabine, FOLFIRINOX, Leucovorin/administration, Aged [MeSH], Pancreatic Neoplasms/pathology [MeSH], Deoxycytidine/administration, Oxaliplatin/therapeutic use [MeSH], Irinotecan/therapeutic use [MeSH], Neoadjuvant Therapy [MeSH], Male [MeSH], Adenocarcinoma/drug therapy [MeSH], Adenocarcinoma/pathology [MeSH], Pancreatectomy [MeSH], Pancreatic Neoplasms/surgery [MeSH], Fluorouracil/administration, Oxaliplatin/administration, Female [MeSH], Follow-Up Studies [MeSH], Leucovorin/therapeutic use [MeSH], Adult [MeSH], Humans [MeSH], Irinotecan/administration, Middle Aged [MeSH], Neoadjuvant, Pancreatic Neoplasms/drug therapy [MeSH], Antineoplastic Combined Chemotherapy Protocols/therapeutic use [MeSH], Gemcitabine [MeSH], Survival Rate [MeSH], Chemotherapy, Adjuvant [MeSH], Resectable pancreatic cancer, Adjuvant, Deoxycytidine/analogs, Prognosis [MeSH], Adenocarcinoma/mortality [MeSH], Adenocarcinoma/surgery [MeSH], Neoadjuvant Therapy, Pancreatic Neoplasms, Oxaliplatin, Survival Rate, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Chemotherapy, Adjuvant, Antineoplastic Combined Chemotherapy Protocols, Humans, Female, Fluorouracil, Aged, Follow-Up Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38459418
https://repository.publisso.de/resource/frl:6502185

The Value of Biological and Conditional Factors for Staging of Patients with Resectable Pancreatic Cancer Undergoing Upfront Resection: A Nationwide Analysis: A Nationwide Analysis

Autori: Schouten, T.J. Goor, I.W.J.M. van Dorland, G.A. a ďalší

Prispievatelia: Schouten, T.J. Goor, I.W.J.M. van Dorland, G.A. a ďalší

Zdroj: Ann Surg Oncol
Schouten, T J, van Goor, I W J M, Dorland, G A, Besselink, M G, Bonsing, B A, Bosscha, K, Brosens, L A A, Busch, O R, Cirkel, G A, van Dam, R M, Festen, S, Groot Koerkamp, B, van der Harst, E, de Hingh, I H J T, Intven, M P W, Kazemier, G, Liem, M S L, van Lienden, K P, Los, M, de Meijer, V E, Patijn, G A, Schreinemakers, J M J, Stommel, M W J, van Tienhoven, G J, Verdonk, R C, Verkooijen, H M, van Santvoort, H C, Molenaar, I Q & Daamen, L A 2024, 'The Value of Biological and Conditional Factors for Staging of Patients with Resectable Pancreatic Cancer Undergoing Upfront Resection : A Nationwide Analysis', Annals of Surgical Oncology, vol. 31, no. 8, pp. 4956-4965. https://doi.org/10.1245/s10434-024-15070-w
Annals of Surgical Oncology, 31, 8, pp. 4956-4965

Predmety: Male, Female [MeSH], Follow-Up Studies [MeSH], Aged [MeSH], Pancreatic Neoplasms/pathology [MeSH], Humans [MeSH], Pancreatic Tumors, Middle Aged [MeSH], Biological factors, CA-19-9 Antigen/blood [MeSH], Neoplasm Staging [MeSH], Survival Rate [MeSH], Conditional factors, Male [MeSH], Carcinoma, Pancreatic Ductal/pathology [MeSH], Pancreatectomy [MeSH], Carcinoma, Pancreatic Ductal/surgery [MeSH], Netherlands/epidemiology [MeSH], Prognosis [MeSH], Pancreatic ductal adenocarcinoma, Biomarkers, Tumor [MeSH], Pancreatic Neoplasms/surgery [MeSH], Pancreatic cancer, CA-19-9 Antigen, Pancreatectomy, SDG 3 - Good Health and Well-being, Journal Article, Biomarkers, Tumor, Humans, Aged, Neoplasm Staging, Netherlands, Pathology - Radboud University Medical Center, Middle Aged, Prognosis, 3. Good health, Pancreatic Neoplasms, Survival Rate, Oncology, Surgery, Female, Surgery - Radboud University Medical Center, Carcinoma, Pancreatic Ductal, Follow-Up Studies

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38386198
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/308562
https://pure.eur.nl/en/publications/404752b0-6a4b-4805-9b00-249837e7ce95
https://doi.org/10.1245/s10434-024-15070-w
https://research.rug.nl/en/publications/91768459-38be-4c96-ab3f-6027f1a3a3c4
https://doi.org/10.1245/s10434-024-15070-w
https://hdl.handle.net/11370/91768459-38be-4c96-ab3f-6027f1a3a3c4
https://research.vumc.nl/en/publications/66f291a8-a9cc-4974-8f58-437e7a76423e
https://dspace.library.uu.nl/handle/1874/454107
https://hdl.handle.net/1887/4209199
https://repository.ubn.ru.nl//bitstream/handle/2066/308562/308562.pdf
https://repository.ubn.ru.nl/handle/2066/308562
https://repository.publisso.de/resource/frl:6503133

Prognostic importance of margin clearance in ampullary adenocarcinoma following pancreaticoduodenectomy in a Danish population-based nationwide study

Autori: Trine Aaquist Claus W. Fristrup Jane P. Hasselby a ďalší

Zdroj: Aaquist, T, Fristrup, C W, Hasselby, J P, Hamilton-Dutoit, S, Eld, M, Pfeiffer, P, Mortensen, M B & Detlefsen, S 2024, 'Prognostic importance of margin clearance in ampullary adenocarcinoma following pancreaticoduodenectomy in a Danish population-based nationwide study', H P B, vol. 26, no. 2, pp. 241-250. https://doi.org/10.1016/j.hpb.2023.10.009
Aaquist, T, Fristrup, C W, Hasselby, J P, Hamilton-Dutoit, S, Eld, M, Pfeiffer, P, Mortensen, M B & Detlefsen, S 2024, 'Prognostic importance of margin clearance in ampullary adenocarcinoma following pancreaticoduodenectomy in a Danish population-based nationwide study', HPB, vol. 26, no. 2, pp. 241-250. https://doi.org/10.1016/j.hpb.2023.10.009

Predmety: Pancreatic Neoplasms, Common Bile Duct Neoplasms/surgery, Pancreatic Neoplasms/pathology, Denmark, Common Bile Duct Neoplasms, Humans, Adenocarcinoma, Prognosis, 3. Good health, Pancreaticoduodenectomy

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37996299
https://vbn.aau.dk/da/publications/300b2872-8621-4406-9375-4d7a99202597
http://www.scopus.com/inward/record.url?scp=85178235386&partnerID=8YFLogxK
https://doi.org/10.1016/j.hpb.2023.10.009
https://portal.findresearcher.sdu.dk/da/publications/7c8f5321-1489-4a48-8f1e-f5841a6cdccf
https://doi.org/10.1016/j.hpb.2023.10.009
http://www.scopus.com/inward/record.url?scp=85178235386&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/58bf4989-15bf-4d01-8344-0e705efa65b4
https://doi.org/10.1016/j.hpb.2023.10.009

Molecular diagnostics of hepatobiliary and pancreatic neoplasias

Autori: T. Longerich A. Stenzinger P. Schirmacher

Zdroj: Virchows Arch

Predmety: Review and Perspectives, Pancreatic Neoplasms, 0301 basic medicine, 03 medical and health sciences, 0302 clinical medicine, Molecular Diagnostic Techniques, Humans, Genetic Predisposition to Disease, Pathology, Molecular, Medical Oncology, Genetic Predisposition to Disease [MeSH], Pancreas, Pancreatic Neoplasms/genetics [MeSH], Medical Oncology [MeSH], Pathology, Molecular [MeSH], Cancer, Pancreatic Neoplasms/pathology [MeSH], Hepatobiliary, Humans [MeSH], Molecular Diagnostic Techniques [MeSH], Personalized Medicine, Molecular diagnostics, Pancreatic Neoplasms/diagnosis [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38429607
https://repository.publisso.de/resource/frl:6524752