Výsledky vyhledávání - "PROTEIN PHOSPHATASE 2A"

Folic acid improves intestinal function in grass carp (Ctenopharyngodon idella): Revealing a new perspective of DNA methyltransferases and PP2A-p38 signaling pathway in intestinal epithelial function

Autoři: Yun Wang Weidan Jiang Pei Wu a další

Zdroj: Animal Nutrition, Vol 23, Iss , Pp 246-256 (2025)

Témata: Folic acid, Intestinal barrier, Methyltransferase, Protein phosphatase 2A, Grass carp, Animal culture, SF1-1100

Popis souboru: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405654525001477; https://doaj.org/toc/2405-6545

Přístupová URL adresa: https://doaj.org/article/0e9a04f4dcd2428d94d674b5a8562c26

In-silico identification and functional analysis of cis-regulatory elements in selected protein phosphatase 2A (PP2A) gene promoters of Arabidopsis thaliana reveals 5′-AAAG-3′ as over-represented motif under abiotic stress condition

Autoři: Zaiba Hasan Khan Yukti Singh Saumya Agrawal a další

Zdroj: BMC Research Notes, Vol 18, Iss 1, Pp 1-12 (2025)

Témata: Protein phosphatase 2A, Abiotic stress, cis-regulatory elements, Gene expression, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

Popis souboru: electronic resource

Relation: https://doaj.org/toc/1756-0500

Přístupová URL adresa: https://doaj.org/article/bcd530ad572d4b14b99530a170686750

PP2A Promotes Epithelial-Mesenchymal Transition in Chronic Rhinosinusitis with Nasal Polyps via Wnt/β-Catenin Pathway: A Novel Insight

Autoři: Chen W Zheng B Shu L a další

Zdroj: Journal of Asthma and Allergy, Vol 18, Iss Issue 1, Pp 1505-1522 (2025)

Témata: chronic rhinosinusitis, Protein Phosphatase 2A, epithelial-mesenchymal transition, nasal polyps, Wnt., Immunologic diseases. Allergy, RC581-607

Popis souboru: electronic resource

Relation: https://www.dovepress.com/pp2a-promotes-epithelial-mesenchymal-transition-in-chronic-rhinosinusi-peer-reviewed-fulltext-article-JAA; https://doaj.org/toc/1178-6965

Přístupová URL adresa: https://doaj.org/article/b91f4d947f24460aa67a2a603f92fdf7

Pathogenic de novo variants in PPP2R5C cause a neurodevelopmental disorder within the Houge-Janssens syndrome spectrum

Autoři: Verbinnen, Iris Douzgou Houge, Sofia Hsieh, Tzung-Chien a další

Zdroj: The American Journal of Human Genetics. 112:554-571

Témata: Male, Adolescent, Mutation, Missense, Infant, PP2A, PPP2R5C, PPP2R5D, autism, developmental delay, epilepsy, intellectual disability, macrocephaly, neurodevelopmental disorder, protein phosphatase 2A, Syndrome, Phenotype, Neurodevelopmental Disorders, Child, Preschool, Intellectual Disability, Humans, Female, Protein Phosphatase 2, Child

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39978342
https://pure.eur.nl/en/publications/979a712c-d9b7-493e-93e9-d082cfb1b59b
https://doi.org/10.1016/j.ajhg.2025.01.021
https://hdl.handle.net/2318/2059653
https://doi.org/10.1016/j.ajhg.2025.01.021

Cerebral endothelial 3-mercaptopyruvate sulfurtransferase improves ischemia-induced cognitive impairment via interacting with protein phosphatase 2A

Autoři: Li Zhu Yi Huang Jing Jin a další

Zdroj: Acta Pharm Sin B
Acta Pharmaceutica Sinica B, Vol 15, Iss 1, Pp 314-330 (2025)

Témata: Hydrogen sulfide, Cerebral endothelium, 3-Mercaptopyruvate sulfurtransferase, Calpain2, Original Article, Therapeutics. Pharmacology, RM1-950, Neuron, Protein phosphatase 2A

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40041885
https://doaj.org/article/25a44ff1721a4306af96957c15b83423

De novo missense variants in the PP2A regulatory subunit PPP2R2B in a neurodevelopmental syndrome: potential links to mitochondrial dynamics and spinocerebellar ataxias: potential links to mitochondrial dynamics and spinocerebellar ataxias

Autoři: Priyanka Sandal Chian Ju Jong Ronald A Merrill a další

Zdroj: Hum Mol Genet
Human Molecular Genetics, 34, 2, pp. 193-203

Témata: MECHANISM, Male, 0301 basic medicine, Adolescent, cerebellar ataxias, dynamin-related protein 1, Developmental Disabilities, Mutation, Missense, Nerve Tissue Proteins, Mitochondrial Dynamics, 03 medical and health sciences, Intellectual Disability, Humans, Spinocerebellar Ataxias, Protein Phosphatase 2, PHOSPHORYLATION, Child, 0303 health sciences, neurodevelopmental disorders, protein phosphatase 2A, PROTEIN PHOSPHATASE 2A, DEPHOSPHORYLATION, mitochondrial dynamics, Mitochondria, Neurodevelopmental Disorders, Child, Preschool, Human Genetics - Development and lifelong plasticity, Original Article, Female

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39565297
https://cris.maastrichtuniversity.nl/en/publications/0b20f186-5244-4bce-a370-eb9993e3a75b
https://doi.org/10.1093/hmg/ddae166
https://repository.ubn.ru.nl//bitstream/handle/2066/315967/315967.pdf
https://hdl.handle.net/2066/315967

Protein phosphatase 2A promotes mitophagy to alleviate fructose-induced mitochondrial oxidative damage in M2-type macrophages

Autoři: LI Xiaoman LAN Li LONG Yijin

Zdroj: 陆军军医大学学报, Vol 47, Iss 18, Pp 2186-2196 (2025)

Témata: fructose, macrophages, mitophagy, oxidative stress, protein phosphatase 2a, Medicine (General), R5-920

Popis souboru: electronic resource

Relation: https://aammt.tmmu.edu.cn/html/202505052.html; https://doaj.org/toc/2097-0927

Přístupová URL adresa: https://doaj.org/article/83453060247f4929baef6b0a73c480e6

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Autoři: Matheus Henrique Dias René Bernards

Zdroj: Molecular Oncology, Vol 19, Iss 9, Pp 2468-2471 (2025)

Témata: biomarker, Immune checkpoint blockade, ovarian cancer, Protein Phosphatase 2A, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Popis souboru: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Přístupová URL adresa: https://doaj.org/article/e22a2790dcbf496eb8a37a762cfda550

PPP2CA knockdown upregulates the expression levels of ferroptosis-related genes TFRC and ACSL4 in colorectal cancer cells by promoting mTOR phosphorylation

Autoři: Jing Cheng Zhihan Liu Haibo Liu a další

Zdroj: Frontiers in Oncology, Vol 15 (2025)

Témata: protein phosphatase 2A catalytic subunit alpha, colorectal cancer, ferroptosis, malignant phenotype, mTOR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Popis souboru: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1694932/full; https://doaj.org/toc/2234-943X

Přístupová URL adresa: https://doaj.org/article/9b244f29cc0347168c77e93ac7ce0f67

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Autoři: Wei‐Peng Hu Ze‐Yu Cai Qing‐Le Li a další

Zdroj: Advanced Science, Vol 12, Iss 37, Pp n/a-n/a (2025)

Témata: aortic aneurysm/dissection, kruppel‐like factor 4, phenotypic switching, protein phosphatase 2A, vascular smooth muscle cell, Science

Popis souboru: electronic resource

Relation: https://doaj.org/toc/2198-3844

Přístupová URL adresa: https://doaj.org/article/23293f85b09849298ea7902ca1e6c95a

The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism

Autoři: Remmerie, Michiel Dok, Rüveyda Wang, Zhigang a další

Zdroj: Cellular Oncology. 47:1811-1829

Témata: 0301 basic medicine, NUCLEOTIDE, Protein phosphatase 2A (PP2A), Apoptosis, DEOXYCYTIDINE KINASE, 0601 Biochemistry and Cell Biology, Gain-of-function (GOF) mutation, 03 medical and health sciences, DRUG-SENSITIVITY, KOTK_KUL/2019/11893/1, 3211 Oncology and carcinogenesis, Cell Line, Tumor, Pathology, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Protein Phosphatase 2, LB-100, NUCLEOSIDE, 0303 health sciences, Science & Technology, Deoxycytidine kinase (dCK), Adenine Nucleotides, INHIBITOR, PROTEIN PHOSPHATASE 2A, Cell Biology, Nucleoside analogue, Uterine serous carcinoma (USC), Cystadenocarcinoma, Serous, 3. Good health, PPP2R1A, Oncology, Drug Resistance, Neoplasm, Uterine Neoplasms, Mutation, SURVIVAL, Female, ANTICANCER, Arabinonucleosides, Life Sciences & Biomedicine, Clofarabine

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38888850

RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis

Autoři: Shu-jie Pang Tian-yi Jiang Nai-guo Wang a další

Zdroj: Cell Communication and Signaling, Vol 23, Iss 1, Pp 1-20 (2025)

Témata: IκB kinase β (IKKβ), RNA polymerase II subunit 5-mediating protein (RMP), NF-κB, Sepsis, Macrophage, Protein phosphatase 2A (PP2A), Medicine, Cytology, QH573-671

Popis souboru: electronic resource

Relation: https://doaj.org/toc/1478-811X

Přístupová URL adresa: https://doaj.org/article/2c4ac83b622c4d3499bc8bca60a3f2f2

Early life seizures chronically disrupt L-type voltage gated calcium channel regulation of mGluR mediated long term depression via interactions with protein phosphatase 2A

Autoři: Paul B. Bernard Anna M. Castano Olivia R. Buonarati a další

Zdroj: Neurobiology of Disease, Vol 209, Iss , Pp 106884- (2025)

Témata: L-type voltage gated Ca2+ channels, CaV1.2, Metabotropic glutamate receptor, Long-term depression, Protein phosphatase 2A, Early life seizure, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

Popis souboru: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996125001007; https://doaj.org/toc/1095-953X

Přístupová URL adresa: https://doaj.org/article/59dcfd4579804579b7ce18b46dd2625c

Cigarette smoke alters calcium flux to induce PP2A membrane trafficking and endothelial cell permeability

Autoři: Abdoulaye J. Dabo Sonya Raghavan Wendy Ezegbunam a další

Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Témata: Chronic obstructive pulmonary disease, Inflammation, Protein phosphatase 2A, Endothelium, Permeability, And cigarette smoke, Medicine, Science

Popis souboru: electronic resource

Relation: https://doaj.org/toc/2045-2322

Přístupová URL adresa: https://doaj.org/article/52d64c38518940ceb10a6b214ae0223c

The Emerging Role of the Cancerous Inhibitor of Protein Phosphatase 2A in Pulmonary Diseases

Autoři: Hamza Hamza Dinesh Nirmal Stephanie Pappas a další

Zdroj: Medicina, Vol 61, Iss 10, p 1740 (2025)

Témata: cancerous inhibitor of PP2A, protein phosphatase 2A, pulmonary diseases, immune responses, cell cycle, signaling transduction, Medicine (General), R5-920

Popis souboru: electronic resource

Relation: https://www.mdpi.com/1648-9144/61/10/1740; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

Přístupová URL adresa: https://doaj.org/article/69b164ad7db7480cbe7cc6453d794428

Evaluating the Potential Inhibition of PP2A by Nodularin-R Disinfection By-Products: Effect and Mechanism

Autoři: Mengchen Li Chunyu Fu Qiannan Shi a další

Zdroj: Toxins, Vol 17, Iss 10, p 484 (2025)

Témata: nodularin-R, disinfection by-products, protein phosphatase 2A, homology modeling, molecular docking, Medicine

Popis souboru: electronic resource

Relation: https://www.mdpi.com/2072-6651/17/10/484; https://doaj.org/toc/2072-6651

Přístupová URL adresa: https://doaj.org/article/dc8fb84db87844a2b14416e78a148975

Carboxy-Methylation of the Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Integrates Methionine Availability with Methionine Addicted Cancer Cell Proliferation

Autoři: Anna Andronicos Kiku C. Yoneda Da-Wei Lin a další

Zdroj: Biomolecules, Vol 15, Iss 9, p 1210 (2025)

Témata: methionine dependence of cancer, methionine restriction, Hoffman effect, protein phosphatase 2A, methylation, Microbiology, QR1-502

Popis souboru: electronic resource

Relation: https://www.mdpi.com/2218-273X/15/9/1210; https://doaj.org/toc/2218-273X

Přístupová URL adresa: https://doaj.org/article/4c93929edce84e7b85018dda8ddce4b2

The phosphatase activity of the PPP2R5D-PP2A holoenzyme modulates liprin-α1 liquid-liquid phase separation

Autoři: Abigail Mayer Rita Derua Elijah Spahn a další

Zdroj: J Biol Chem

Témata: Biochemistry & Molecular Biology, Houge-Janssens syndrome (HSJ), Phase Separation, intrinsically disordered protein domain, Humans, mass spectrometry (MS), Protein Phosphatase 2, Phosphorylation, 11 Medical and Health Sciences, Adaptor Proteins, Signal Transducing, fluorescence recovery after photobleaching (FRAP), Science & Technology, protein phosphatase 2A (PP2A), phosphorylation, 31 Biological sciences, liprin-α1, 32 Biomedical and clinical sciences, 06 Biological Sciences, 34 Chemical sciences, HEK293 Cells, liprin-β1, phase separation, Holoenzymes, 03 Chemical Sciences, Life Sciences & Biomedicine, Research Article

Expression of CIP2A and CD44v6 in condyloma acuminatum-involved skin and its correlation with patients' prognosis

Autoři: ZHANG Yijie YANG Can LIN Yongli

Zdroj: Pifu-xingbing zhenliaoxue zazhi, Vol 31, Iss 8, Pp 511-517 (2024)

Témata: pointed condyloma, cancerous inhibitor of protein phosphatase 2a, cd44v6, human papillomavirus, prognosis, Dermatology, RL1-803

Popis souboru: electronic resource

Relation: http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.08.001; https://doaj.org/toc/1674-8468

Přístupová URL adresa: https://doaj.org/article/8f660d7ff21445f48f2d9c56188a70a4

Germacrone Ameliorates Diabetic Kidney Disease by Activating TFEB to Promote Autophagy and Inhibit Inflammation

Autoři: Zhishen Xie Mengmeng Wang Qingqing Song a další

Témata: Biochemistry, Microbiology, Genetics, Molecular Biology, Physiology, Pharmacology, Immunology, Developmental Biology, Marine Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcription factor eb, stage renal disease, docking results indicated, protein phosphatase 2a, findings highlighted ger, autophagy inhibitor chloroquine, underlying molecular mechanism, clear nlrp3 inflammasomes, ger activated tfeb, underlying mechanism, significantly activated, tfeb protein, protein caused, promote autophagy, activating autophagy, widely recognized, vivo <, vitro <, tfeb pathway

Relation: https://figshare.com/articles/journal_contribution/Germacrone_Ameliorates_Diabetic_Kidney_Disease_by_Activating_TFEB_to_Promote_Autophagy_and_Inhibit_Inflammation/29597398

Dostupnost: https://doi.org/10.1021/acsomega.5c00038.s001
https://figshare.com/articles/journal_contribution/Germacrone_Ameliorates_Diabetic_Kidney_Disease_by_Activating_TFEB_to_Promote_Autophagy_and_Inhibit_Inflammation/29597398