Search Results - "Oxidative Phosphorylation/drug effects"

T cell toxicity induced by tigecycline binding to the mitochondrial ribosome

Authors: Qiuya Shao Anas Khawaja Minh Duc Nguyen et al.

Source: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)
Shao, Q, Khawaja, A, Nguyen, M D, Singh, V, Zhang, J, Liu, Y, Nordin, J, Adori, M, Axel Innis, C, Castro Dopico, X & Rorbach, J 2025, 'T cell toxicity induced by tigecycline binding to the mitochondrial ribosome', Nature Communications, vol. 16, no. 1, 4080. https://doi.org/10.1038/s41467-025-59388-9

Subject Terms: Protein Biosynthesis/drug effects, Binding Sites, Science, T-Lymphocytes, Cryoelectron Microscopy, Mitochondrial Ribosomes/metabolism, Minocycline, Tigecycline, Article, Oxidative Phosphorylation, Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents, Mitochondria, Mitochondrial Ribosomes, T-Lymphocytes/drug effects, Minocycline/analogs & derivatives, Protein Biosynthesis, Mitochondria/metabolism, Humans, Tigecycline/toxicity, Oxidative Phosphorylation/drug effects

Access URL: https://pubmed.ncbi.nlm.nih.gov/40312422
https://doaj.org/article/e532be8fc8144233af66616996fe94f8

Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer

Authors: Alicia-Marie K. Beier Celina Ebersbach Tiziana Siciliano et al.

Source: Oncogene

Subject Terms: Male, 0301 basic medicine, 0303 health sciences, Glutamine, Prostatic Neoplasms, Antineoplastic Agents, Docetaxel, Article, Oxidative Phosphorylation, 03 medical and health sciences, Glutaminase, Drug Resistance, Neoplasm, Cell Line, Tumor, 96/34, Cell Line, Tumor [MeSH], Prostatic Neoplasms/metabolism [MeSH], Prostatic Neoplasms/drug therapy [MeSH], Prostatic Neoplasms/pathology [MeSH], Antineoplastic Agents/pharmacology [MeSH], 96/109, 96/31, 13/51, Glutaminase/antagonists, Male [MeSH], 631/67/2327, Glutaminase/genetics [MeSH], 96/63, Drug Resistance, Neoplasm [MeSH], Docetaxel/pharmacology [MeSH], Humans [MeSH], Glutamine/metabolism [MeSH], 631/67/589/466, Oxidative Phosphorylation/drug effects [MeSH], Prostatic Neoplasms/genetics [MeSH], Glutaminase/metabolism [MeSH], Antineoplastic Agents/therapeutic use [MeSH], 38/89, 13/105, Cell Proliferation/drug effects [MeSH], article, Humans, Cell Proliferation

Access URL: https://pubmed.ncbi.nlm.nih.gov/38750263
https://repository.publisso.de/resource/frl:6504923

CDK6 kinase inhibition unmasks metabolic dependencies in BCR::ABL1+ leukemia

Authors: Scheiblecker, Lisa Klampfl, Thorsten Doma, Eszter et al.

Source: Cell Death Dis
Cell Death and Disease, Vol 16, Iss 1, Pp 1-11 (2025)

Subject Terms: Cyclin-Dependent Kinase 6 Antagonists & Inhibitors, Imatinib Mesylate Pharmacology, Pyridines, Mitochondria Drug Effects, Fusion Proteins, bcr-abl, Protein Kinase Inhibitors Pharmacology, Deoxy Glucose, Leukemia, Myelogenous, Chronic, BCR-ABL Positive Pathology, Imatinib Mesylate Therapeutic Use, Apoptosis, Deoxyglucose, Article, Piperazines, Oxidative Phosphorylation, Leukemia, Myelogenous, Chronic, BCR-ABL Positive Metabolism, Cell Drug Effects, Drug Resistance, Neoplasm Drug Effects, Cell Line, Tumor, Fusion Proteins, bcr-abl Metabolism, Oxidative Phosphorylation Drug Effects, Humans, Mitochondria Metabolism, Protein Kinase Inhibitors, Cell Proliferation, Glycolysisdrug Effects, Leukemia, QH573-671, Cyclin-Dependent Kinase 6, Leukemia, Myelogenous, Chronic, BCR-ABL Positive Genetics, Piperazines Pharmacology, Pyridines Pharmacology, Leukemia, Myelogenous, Chronic, BCR-ABL Positive Drug Therapy, Fusion Proteins, bcr-abl Genetics, Mitochondria, Cyclin-Dependent Kinase 6 Metabolism, Drug Resistance, Neoplasm, Apoptosisdrug Effects, Imatinib Mesylate, Deoxy Pharmacology, K562 Cells, Cytology, Glycolysis

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39966356
https://doaj.org/article/febe63f417904fd6ae1fd7ef05515b55
https://phaidra.vetmeduni.ac.at/o:3977
https://doi.org/10.1038/s41419-025-07434-1

Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival

Authors: Komza, M. Khatun, J. Gelles, J.D. et al.

Source: Cell Commun Signal
Cell Communication and Signaling, Vol 23, Iss 1, Pp 1-23 (2025)
Cell communication and signaling, vol. 23, no. 1, pp. 47

Subject Terms: Adaptations, Leukemia, QH573-671, Cell Survival, Research, Humans, Mitochondria/metabolism, Mitochondria/drug effects, Glucose/metabolism, Cell Survival/drug effects, Leukemia, Myeloid, Acute/pathology, Leukemia, Myeloid, Acute/metabolism, Leukemia, Myeloid, Acute/genetics, Leukemia, Myeloid, Acute/drug therapy, Cell Respiration/drug effects, Glycolysis/drug effects, Oxidative Phosphorylation/drug effects, Cell Line, Tumor, Adaptation, Physiological, Bioenergetics, Cancer, Chemotherapy, Glucose, Metabolism, Mitochondria, Oncogenes, Stem cells, Cell Respiration, Oxidative Phosphorylation, Leukemia, Myeloid, Acute, Medicine, Cytology, Glycolysis

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39863913
https://doaj.org/article/1ee0edd56afb478b807dd13d66caf1ab
https://serval.unil.ch/resource/serval:BIB_903FD8FB36B8.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_903FD8FB36B8
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_903FD8FB36B84

Targeting the Electron Transport System for Enhanced Longevity

Authors: Radovic, Marko Gartzke, Lucas P Wink, Simon E et al.

Source: Radovic, M, Gartzke, L P, Wink, S E, van der Kleij, J A, Politiek, F A & Krenning, G 2025, 'Targeting the Electron Transport System for Enhanced Longevity', Biomolecules, vol. 15, no. 5, 614. https://doi.org/10.3390/biom15050614

Subject Terms: Humans, Longevity/drug effects, Electron Transport/drug effects, Metformin/pharmacology, Animals, Mitochondria/metabolism, Sirolimus/pharmacology, Reactive Oxygen Species/metabolism, Oxidative Phosphorylation/drug effects

File Description: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/40427507; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/ba16c68f-7ad9-4011-90d6-dde37981aaf8; info:eu-repo/semantics/altIdentifier/pissn/2218-273X; info:eu-repo/semantics/altIdentifier/eissn/2218-273X

Availability: https://hdl.handle.net/11370/ba16c68f-7ad9-4011-90d6-dde37981aaf8
https://research.rug.nl/en/publications/ba16c68f-7ad9-4011-90d6-dde37981aaf8
https://doi.org/10.3390/biom15050614
https://pure.rug.nl/ws/files/1326108163/biomolecules-15-00614-v2.pdf
https://www.scopus.com/pages/publications/105006678175

Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma

Authors: Chiara Raggi Maria Letizia Taddei Elena Sacco et al.

Contributors: Chiara Raggi Maria Letizia Taddei Elena Sacco et al.

Source: Raggi, C, Taddei, M L, Sacco, E, Navari, N, Correnti, M, Piombanti, B, Pastore, M, Campani, C, Pranzini, E, Iorio, J, Lori, G, Lottini, T, Peano, C, Cibella, J, Lewinska, M, Andersen, J B, di Tommaso, L, Viganò, L, Di Maira, G, Madiai, S, Ramazzotti, M, Orlandi, I, Arcangeli, A, Chiarugi, P & Marra, F 2021, ' Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma ', Journal of Hepatology, vol. 74, no. 6, pp. 1373-1385 . https://doi.org/10.1016/j.jhep.2020.12.031

Subject Terms: Male, 0301 basic medicine, Indoles, Carcinogenesis, PGC-1α, Mice, SCID, Oxidative Phosphorylation, CCLP1, HUCCT1, OXPHOS, SR-18292, Cholangiocarcinoma, Mice, Metformin/administration & dosage, Mice, Inbred NOD, Signal Transduction/drug effects, PGC-1?, Propanols/administration & dosage, Oxidative Phosphorylation/drug effects, 0303 health sciences, Tumor, Electron Transport Complex II, Indoles/administration & dosage, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/antagonists & inhibitors, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Progression-Free Survival, Metformin, Mitochondria, 3. Good health, Treatment Outcome, Phenotype, Neoplastic Stem Cells, Epithelial-Mesenchymal Transition/drug effects, Electron Transport Complex II/metabolism, Tumor Burden/drug effects, Epithelial-Mesenchymal Transition, SCID, Transfection, Cell Line, 03 medical and health sciences, Neoplastic Stem Cells/metabolism, Cell Line, Tumor, Mitochondria/metabolism, Cholangiocarcinoma/drug therapy, Animals, Humans, Gene Silencing, Bile Duct Neoplasms/drug therapy, Carcinogenesis/drug effects, Xenograft Model Antitumor Assays, Bile Duct Neoplasms, Inbred NOD

File Description: application/pdf; STAMPA

Access URL: https://pubmed.ncbi.nlm.nih.gov/33484774
https://www.ncbi.nlm.nih.gov/pubmed/33484774
https://boa.unimib.it/handle/10281/314811
https://pubmed.ncbi.nlm.nih.gov/33484774/
https://air.unimi.it/handle/2434/825203
https://www.sciencedirect.com/science/article/pii/S0168827821000246
https://europepmc.org/article/MED/33484774
https://hdl.handle.net/20.500.14243/450171
http://www.scopus.com/record/display.url?eid=2-s2.0-85104152123&origin=inward
https://doi.org/10.1016/j.jhep.2020.12.031
https://hdl.handle.net/2434/825203
https://doi.org/10.1016/j.jhep.2020.12.031
https://hdl.handle.net/10281/314811
https://doi.org/10.1016/j.jhep.2020.12.031
https://www.journal-of-hepatology.eu/article/S0168-8278(21)00024-6/fulltext
https://hdl.handle.net/11365/1286695
https://doi.org/10.1016/j.jhep.2020.12.031
https://curis.ku.dk/ws/files/333036705/mitochondrial_oxidative_metabolism_in_cca.pdf
https://hdl.handle.net/2158/1223058
https://doi.org/10.1016/j.jhep.2020.12.031

Chronic ethanol ingestion increases efficiency of oxidative phosphorylation in rat liver mitochondria

Authors: Piquet, M. A. Nogueira, V. Devin, A. et al.

Subject Terms: Alcohol Drinking/metabolism Alcoholic Intoxication/metabolism Alcoholism/*metabolism Animals Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology Electron Transport Complex IV/antagonists & inhibitors/metabolism Hydrogen-Ion Concentration Kinetics Male Mitochondria, Liver/drug effects/*metabolism Oligomycins/pharmacology *Oxidative Phosphorylation/drug effects Oxygen Consumption/drug effects Rats Rats, Wistar Rotenone/pharmacology Sodium Azide/pharmacology

Relation: FEBS Letters; https://iris.unil.ch/handle/iris/70818; serval:BIB_1AF5DEE59F96; 000085662000027

Availability: https://iris.unil.ch/handle/iris/70818
https://doi.org/10.1016/S0014-5793(00)01225-4

Mitochondrial polarization in rat hippocampal astrocytes is resistant to cytosolic Ca(2+) loads

Authors: Kahlert, S. Schild, L. Reiser, G.

Subject Terms: Adenosine Triphosphate/metabolism Animals Animals, Newborn Astrocytes/drug effects/*metabolism Brain Ischemia/*metabolism/physiopathology Calcium/*metabolism Cells, Cultured Cytochrome c Group/metabolism/pharmacology Cytosol/drug effects/*metabolism Energy Metabolism/drug effects/*physiology Enzyme Inhibitors/pharmacology Fluorescent Dyes/diagnostic use Glycolysis/drug effects/physiology Hippocampus/drug effects/*metabolism/physiopathology Intracellular Membranes/drug effects/metabolism Ionophores/pharmacology Membrane Potentials/drug effects/physiology Membrane Transport Proteins/drug effects/physiology Mitochondria/drug effects/*metabolism Oxidative Phosphorylation/drug effects Rats Rats, Wistar

Relation: Journal of Neuroscience Research; https://iris.unil.ch/handle/iris/60929; serval:BIB_44BF3D8645D7; 000172562200037

Availability: https://iris.unil.ch/handle/iris/60929
https://doi.org/10.1002/jnr.10052

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies

Authors: Kim, Yonghyo Doma, Viktória Çakır, Uğur et al.

Source: Cancer; 131(13), no e35897 (2025) ; ISSN: 1097-0142

Subject Terms: Basic Cancer Research, Cancer and Oncology, Humans, Melanoma/pathology, Proteome/metabolism, Mitochondria/metabolism, Oxidative Phosphorylation/drug effects, Skin Neoplasms/pathology, Cell Line, Tumor, Mitochondrial Proteins/metabolism, Proteomics/methods, Female, Apoptosis/drug effects, Male, Proto-Oncogene Proteins B-raf/genetics, Prospective Studies, Cell Proliferation/drug effects, Drug Resistance, Neoplasm, Middle Aged

Relation: http://dx.doi.org/10.1002/cncr.35897; pmid:40545870; scopus:105008731411

Availability: https://lup.lub.lu.se/record/69abfc43-90c8-4c1c-807d-132eddd7fdc5
https://doi.org/10.1002/cncr.35897

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

Authors: Lopes, Fernando Keita, Åsa V Saxena, Alpana et al.

Source: Journal of Biological Chemistry, vol 293, iss 9

Subject Terms: Male, 0301 basic medicine, Biomedical and clinical sciences, Crohn's Disease, Epithelium/drug effects, Medical and Health Sciences, Oral and gastrointestinal, intestinal barrier function, Epithelium, Oxidative Phosphorylation, Mice, oxidative metabolism, DAPK1, bacteria, Oxidative Phosphorylation/drug effects, Tumor, Escherichia coli/drug effects, Tunicamycin, Biological Sciences, Endoplasmic Reticulum Stress, Death-Associated Protein Kinases/metabolism, Mitochondria/drug effects, Mitochondria, 3. Good health, mitochondria, Biological sciences, endoplasmic reticulum stress, Female, epithelial barrier, autophagy, Biochemistry & Molecular Biology, Tunicamycin/pharmacology, Autoimmune Disease, Permeability, Cell Line, 03 medical and health sciences, inflammatory bowel disease, Cell Line, Tumor, Endoplasmic Reticulum Stress/drug effects, Escherichia coli, Animals, Humans, bacterial translocation, Aged, mitochondrial stress, Biomedical and Clinical Sciences, epithelial cell, Inflammatory Bowel Disease, Activating Transcription Factor 6/metabolism, Activating Transcription Factor 6, Death-Associated Protein Kinases, Chemical sciences, IBD basic research, Chemical Sciences, Biochemistry and Cell Biology, Digestive Diseases

Access URL: http://www.jbc.org/content/293/9/3073.full.pdf
https://pubmed.ncbi.nlm.nih.gov/29317503
http://liu.diva-portal.org/smash/record.jsf?pid=diva2%3A1199527
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836131
https://www.jbc.org/article/S0021-9258(20)39046-3/fulltext
https://www.jbc.org/content/293/9/3073.full
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836131
https://pubmed.ncbi.nlm.nih.gov/29317503/
https://escholarship.org/uc/item/1p21f9f6

The antibiotic doxycycline impairs cardiac mitochondrial and contractile function

Authors: Wüst, R.C.I. Coolen, B.F. Held, N.M. et al.

Source: Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks‐Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, 'The antibiotic doxycycline impairs cardiac mitochondrial and contractile function', International Journal of Molecular Sciences, vol. 22, no. 8, 4100, pp. 1-19. https://doi.org/10.3390/ijms22084100

Subject Terms: Aging/metabolism, Animals, Anti-Bacterial Agents/pharmacology, Calcium/metabolism, Calcium Signaling/drug effects, Cell Respiration/drug effects, Cytosol/metabolism, Diabetes Mellitus, Experimental/pathology, Diastole/drug effects, Doxycycline/pharmacology, Drosophila melanogaster/drug effects, Electron Transport Complex I/metabolism, Electron Transport Complex II/metabolism, Glucose/metabolism, Glycolysis/drug effects, Male, Mice, Inbred C57BL, Mitochondria, Heart/drug effects, Mitochondrial Proteins/metabolism, Myocardial Contraction/drug effects, Myocytes, Cardiac/drug effects, Nuclear Proteins/metabolism, Oxidative Phosphorylation/drug effects, Rats, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Relation: info:eu-repo/semantics/altIdentifier/pmid/33921053; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1871.1/a482a5ee-18e2-449f-b5ac-daaa2bf31091; info:eu-repo/semantics/altIdentifier/pissn/1422-0067

Availability: https://research.vu.nl/en/publications/a482a5ee-18e2-449f-b5ac-daaa2bf31091
https://doi.org/10.3390/ijms22084100
https://hdl.handle.net/1871.1/a482a5ee-18e2-449f-b5ac-daaa2bf31091
https://www.scopus.com/pages/publications/85104159105
https://www.scopus.com/inward/citedby.url?scp=85104159105&partnerID=8YFLogxK

Postconditioning With Cyclosporine A Reduces Early Renal Dysfunction by Inhibiting Mitochondrial Permeability Transition

Authors: Lemoine, Sandrine Pillot, B. Rognant, N. et al.

Contributors: Lemoine, Sandrine Pillot, B. Rognant, N. et al.

Source: Transplantation. 99:717-723

Subject Terms: Kidney Transplantation/adverse effects/*methods, Mitochondrial Membrane Transport Proteins/*antagonists & inhibitors/metabolism, Male, 0301 basic medicine, Time Factors, Reperfusion Injury/metabolism/pathology/physiopathology/*prevention & control, [SDV]Life Sciences [q-bio], Mitochondria/*drug effects/metabolism/pathology, Apoptosis, Kidney, Mitochondrial Membrane Transport Proteins, Nephrectomy, Oxidative Phosphorylation, Mice, 03 medical and health sciences, Immunosuppressive Agents/*administration & dosage, Models, Animals, Ischemic Postconditioning, Inbred BALB C, Oxidative Phosphorylation/drug effects, Mice, Inbred BALB C, 0303 health sciences, Animal, Mitochondrial Permeability Transition Pore, Apoptosis/drug effects, Cyclosporine/*administration & dosage, Creatinine/blood, Kidney/*drug effects/metabolism/pathology/physiopathology/*surgery, Kidney Transplantation, Mitochondria, 3. Good health, [SDV] Life Sciences [q-bio], Cytoprotection, 13. Climate action, Creatinine, Reperfusion Injury, Models, Animal, Cyclosporine, Ischemic Postconditioning/*methods, Urea/blood, Biomarkers/blood, Biomarkers, Immunosuppressive Agents

Access URL: https://pubmed.ncbi.nlm.nih.gov/25793558
https://pubmed.ncbi.nlm.nih.gov/25793558/
https://hal.archives-ouvertes.fr/hal-01850624
http://www.ncbi.nlm.nih.gov/pubmed/25793558/
https://hal.science/hal-01850624v1
https://doi.org/10.1097/tp.0000000000000530

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg‐like metabolism?

Authors: Escoll, Pedro Buchrieser, Carmen Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria et al.

Contributors: Escoll, Pedro Buchrieser, Carmen Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria et al.

Source: ISSN: 1742-464X.

Subject Terms: Bacterial infection, Glycolysis, Mitochondria, OXPHOS, Warburg-like metabolism, MESH: Animals, MESH: Bacteria/growth & development, MESH: Cell Differentiation, MESH: Cell Proliferation, MESH: Interleukin-1beta/immunology, MESH: Cellular Reprogramming/drug effects, MESH: Glycolysis/genetics, MESH: Host-Pathogen Interactions, MESH: Humans, MESH: Interleukin-1beta/biosynthesis, MESH: Lipopolysaccharides/pharmacology, MESH: Macrophages/drug effects, MESH: Mitochondria/metabolism, MESH: Macrophages/immunology, MESH: Macrophages/metabolism, MESH: Macrophages/microbiology, MESH: Mitochondria/drug effects, MESH: Mitochondria/immunology, MESH: Mitochondria/microbiology, MESH: Bacteria/pathogenicity, MESH: Oxidative Phosphorylation/drug effects, MESH: T-Lymphocytes/drug effects, MESH: T-Lymphocytes/immunology, MESH: T-Lymphocytes/metabolism, MESH: T-Lymphocytes/microbiology

Relation: info:eu-repo/semantics/altIdentifier/pmid/29603622; PUBMED: 29603622

Availability: https://pasteur.hal.science/pasteur-02437195
https://pasteur.hal.science/pasteur-02437195v1/document
https://pasteur.hal.science/pasteur-02437195v1/file/2018%20FEBS_Escoll.pdf
https://doi.org/10.1111/febs.14446

Disruption of Oxidative Phosphorylation (OXPHOS) by Hydroxylated Polybrominated Diphenyl Ethers (OH-PBDEs) Present in the Marine Environment

Authors: Lillemor Asplund Jessica Legradi Anna-Karin Dahlberg et al.

Source: Environmental Science & Technology. 48:14703-14711

Subject Terms: 0301 basic medicine, Embryo, Nonmammalian, Mytilus edulis, Adenosine Triphosphate/metabolism, Cells, Mytilus edulis/metabolism, Chemical/toxicity, Halogenated Diphenyl Ethers/toxicity, Ecotoxicology, Hydroxylation, Membrane Potential, 01 natural sciences, Oxidative Phosphorylation, Dose-Response Relationship, 03 medical and health sciences, Adenosine Triphosphate, Halogenated Diphenyl Ethers, Animals, Humans, Water Pollutants, SDG 14 - Life Below Water, 14. Life underwater, Nonmammalian/cytology, Cells, Cultured, Zebrafish, Oxidative Phosphorylation/drug effects, 0105 earth and related environmental sciences, Membrane Potential, Mitochondrial, Cultured, Dose-Response Relationship, Drug, 4. Education, Mitochondrial/drug effects, Ecotoxicology/methods, Rats, 3. Good health, Embryo, 13. Climate action, Zebrafish/embryology, Drug, Water Pollutants, Chemical

Access URL: https://pubmed.ncbi.nlm.nih.gov/25422162
https://hdl.handle.net/1871.1/a95da2c9-7b7d-4824-a324-d3113ddd967c
https://doi.org/10.1021/es5039744
https://research.vu.nl/en/publications/a95da2c9-7b7d-4824-a324-d3113ddd967c
https://www.ncbi.nlm.nih.gov/pubmed/25422162
http://ui.adsabs.harvard.edu/abs/2014EnST...4814703L/abstract
https://pubs.acs.org/doi/full/10.1021/es5039744
https://pubag.nal.usda.gov/catalog/5357567
http://www.diva-portal.org/smash/record.jsf?pid=diva2:778165
http://pubs.acs.org/doi/10.1021/es5039744

Ubiquitous protective effects of cyclosporine A in preventing cardiac arrest-induced multiple organ failure

Authors: Maryline Abrial Vincent Jahandiez Abdallah Gharib et al.

Contributors: Maryline Abrial Vincent Jahandiez Abdallah Gharib et al.

Source: Journal of Applied Physiology. 117:930-936

Subject Terms: Cardiotonic Agents, [SDV]Life Sciences [q-bio], Multiple Organ Failure, Cell Respiration, Myocardial Reperfusion Injury, Mitochondria/drug effects/pathology, Mitochondrial Membrane Transport Proteins, Oxidative Phosphorylation, 03 medical and health sciences, 0302 clinical medicine, Cyclosporine/*pharmacology, Cell Respiration/drug effects, Animals, Oxidative Phosphorylation/drug effects, Heart Arrest/*physiopathology, Mitochondrial Permeability Transition Pore, Hemodynamics, Multiple Organ Failure/physiopathology/*prevention & control, Heart Arrest, Mitochondria, 3. Good health, [SDV] Life Sciences [q-bio], Hemodynamics/drug effects, Cardiotonic Agents/*pharmacology, Mitochondrial Membrane Transport Proteins/metabolism, Cyclosporine, Rabbits, Myocardial Reperfusion Injury/drug therapy/physiopathology

Access URL: https://pubmed.ncbi.nlm.nih.gov/25213634
https://jap.physiology.org/content/jap/117/8/930.full.pdf
https://www.physiology.org/doi/full/10.1152/japplphysiol.00495.2014
https://www.ncbi.nlm.nih.gov/pubmed/25213634
https://journals.physiology.org/doi/full/10.1152/japplphysiol.00495.2014
https://jap.physiology.org/content/117/8/930
https://hal.science/hal-01859551v1
https://doi.org/10.1152/japplphysiol.00495.2014

Mitochondrial Oxidative Phosphorylation Reserve Is Required for Hormone- and PPARγ Agonist-Induced Adipogenesis

Authors: Seong Eun Lee Soung Jung Kim Hyo Kyun Chung et al.

Contributors: Seong Eun Lee Soung Jung Kim Hyo Kyun Chung et al.

Source: Molecules and Cells. 35:134-141

Subject Terms: 0301 basic medicine, Oxidative Phosphorylation/drug effects, Cell Cycle Proteins, Inbred C57BL, Oxidative Phosphorylation, Rosiglitazone, Gene Knockout Techniques, Mice, 03 medical and health sciences, 3T3-L1 Cells, Ethidium, Animals, Adipogenesis/drug effects, Cell Cycle Proteins/genetics, PAR gamma/genetics, 0303 health sciences, PPAR gamma/agonists, Adipogenesis, Thiazolidinediones/pharmacology, Ethidium/pharmacology, Membrane Proteins, Cell Cycle Proteins/metabolism, Cyclooxygenase 1/metabolism, Mitochondria/metabolism, Mitochondria, Adiponectin/agonists, Fatty Acid Synthase, Type I, Mice, Inbred C57BL, PPAR gamma, Fatty Acid Synthase, Cyclooxygenase 1, Membrane Proteins/metabolism, Thiazolidinediones, Type I/metabolism, Adiponectin

Access URL: https://europepmc.org/articles/pmc3887907?pdf=render
https://pubmed.ncbi.nlm.nih.gov/23456335
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158476
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887907
https://link.springer.com/article/10.1007%2Fs10059-012-2257-1
http://dspace.kci.go.kr/handle/kci/67454
https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/158476/1/T201306194.pdf
https://pubmed.ncbi.nlm.nih.gov/23456335/

Vibrio vulnificus-induced Cell Death of Human Mononuclear Cells Requires ROS-dependent Activation of p38 and ERK 1/2 MAPKs

Authors: Woo Hyang Kim Soon-Jung Park Kyu-Ho Lee et al.

Contributors: Woo Hyang Kim Soon-Jung Park Kyu-Ho Lee et al.

Source: Immunological Investigations. 38:31-48

Subject Terms: Nitric Oxide Synthase Type II/immunology, 0301 basic medicine, Nitric Oxide/antagonists & inhibitors, Vibrio Infections/immunology, Nitric Oxide Synthase Type II, p38 Mitogen-Activated Protein Kinases, Human peripheral blood mononuclear cells, Oxidative Phosphorylation, Onium Compounds/pharmacology, Onium Compounds, Cell Death/drug effects, Signal Transduction/drug effects, Leukocytes, Mononuclear/microbiology, Vibrio vulnificus/immunology, Mitogen-activated protein kinases, Extracellular Signal-Regulated MAP Kinases, Vibrio vulnificus, Cells, Cultured, Oxidative Phosphorylation/drug effects, Reactive Oxygen Species/antagonists & inhibitors, p38 Mitogen-Activated Protein Kinases/metabolism, 0303 health sciences, Cell Death/immunology, Cultured, Cell Death, Mononuclear/pathology, Extracellular Signal-Regulated MAP Kinases/metabolism, Vibrio Infections/enzymology, Reactive Oxygen Species/immunology, Enzyme Activation/drug effects, Nitric Oxide Synthase Type II/metabolism, Signal Transduction, Extracellular Signal-Regulated MAP Kinases/immunology, Cells, Vibrio vulnificus/pathogenicity, Nitric Oxide, Nitric Oxide/immunology, Mononuclear/metabolism, 03 medical and health sciences, Humans, p38 Mitogen-Activated Protein Kinases/immunology, Mononuclear/immunology, Enzyme Activation, Vibrio Infections, Leukocytes, Mononuclear, Reactive oxygen species, Reactive Oxygen Species

File Description: 31~48

Access URL: https://pubmed.ncbi.nlm.nih.gov/19172484
https://www.tandfonline.com/doi/full/10.1080/08820130802500583
https://www.ncbi.nlm.nih.gov/pubmed/19172484
http://europepmc.org/abstract/MED/19172484

Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin

Contributors: College of Medicine Dept. of Neurosurgery Eui Hyun Kim et al.

Subject Terms: Animals, Antimetabolites/pharmacology, Apoptosis/drug effects, Brain Neoplasms/drug therapy, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Cell Proliferation/drug effects, Deoxyglucose/pharmacology, Drug Synergism, Drug Therapy, Combination, Energy Metabolism/drug effects, Glioblastoma/drug therapy, Glioblastoma/metabolism, Glioblastoma/pathology, Glycolysis/drug effects, Humans, Hypoglycemic Agents/pharmacology, Metformin/pharmacology, Mice, Nude, Oxidative Phosphorylation/drug effects, Tumor Cells, Cultured, Xenograft Model Antitumor Assays, 2-deoxyglucose, glioblastoma, invasion, metformin, stemness

Relation: NEURO-ONCOLOGY; J02346; https://ir.ymlib.yonsei.ac.kr/handle/22282913/153583; T201700387; 42283

Availability: https://ir.ymlib.yonsei.ac.kr/handle/22282913/153583
https://doi.org/10.1093/neuonc/now174
https://academic.oup.com/neuro-oncology/article-lookup/doi/10.1093/neuonc/now174

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

Authors: Pirinen, E. Kuulasmaa, T. Pietila, M. et al.

Source: Mol Cell Biol. 27(13):4953-67

Subject Terms: Medical and Health Sciences, Medicin och hälsovetenskap, Acetyltransferases/metabolism, Adenosine Triphosphate/metabolism, Adipocytes/drug effects/metabolism, Adipose Tissue, White/cytology/drug effects/enzymology/*growth &, development, Animals, Body Composition/drug effects, *Energy Metabolism/drug effects, Feeding Behavior/drug effects, Fibroblasts/drug effects/metabolism, Food Deprivation, Gene Expression Regulation, Enzymologic/drug effects, Glucose/*metabolism, Glucose Intolerance, *Homeostasis/drug effects, Hydrogen Peroxide/pharmacology, Isoenzymes/genetics/metabolism, Macrophages/cytology/drug effects/metabolism, Mice, Mitochondria/drug effects/metabolism, Multienzyme Complexes/genetics/metabolism, Organ Size/drug effects, Oxidative Phosphorylation/drug effects, Phosphorylation/drug effects, Polyamines/*metabolism, Protein-Serine-Threonine Kinases/genetics/metabolism, Trans-Activators/genetics/metabolism, p38 Mitogen-Activated Protein Kinases/metabolism

Access URL: https://gup.ub.gu.se/publication/50449

The impact of mitochondrial genetics on male infertility

Authors: St John, Justin C. Jokhi, Roobin P. Barratt, Christopher L. R.

Source: International Journal of Andrology. 28:65-73

Subject Terms: Male, 0301 basic medicine, Nuclear Proteins/physiology, Transcription Factors/physiology, Mitochondrial/genetics, DNA, Mitochondrial, Oxidative Phosphorylation, DNA-Binding Proteins/physiology, Sperm Motility/drug effects, Mitochondrial Proteins, 03 medical and health sciences, Rotenone, Male/genetics, Testis, Animals, Humans, Potassium Cyanide, Testis/cytology, Infertility, Male, Oxidative Phosphorylation/drug effects, 0303 health sciences, Mitochondrial Myopathies/genetics, Mitochondrial Myopathies, Nuclear Proteins, DNA, Oligomycins/pharmacology, DNA-Binding Proteins, Rotenone/pharmacology, Mitochondrial Proteins/physiology, Infertility, Sperm Motility, Oligomycins, Potassium Cyanide/pharmacology, Gene Deletion, Transcription Factors

Access URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2605.2005.00515.x
https://pubmed.ncbi.nlm.nih.gov/15811066
https://europepmc.org/article/MED/15811066
https://research.monash.edu/en/publications/the-impact-of-mitochondrial-genetics-on-male-infertility
https://pubmed.ncbi.nlm.nih.gov/15811066/
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2605.2005.00515.x
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2605.2005.00515.x
https://www.ncbi.nlm.nih.gov/pubmed/15811066