Výsledky vyhľadávania - "Organ Specificity"

A cross-tissue transcriptome-wide association study identifies novel candidate genes associated with brain glymphatic system function.

Autori: Zhu X Wang S Zhang S a ďalší

Zdroj: Molecular brain [Mol Brain] 2025 Dec 05; Vol. 18 (1), pp. 90. Date of Electronic Publication: 2025 Dec 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606 (Electronic) Linking ISSN: 17566606 NLM ISO Abbreviation: Mol Brain Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genome-Wide Association Study* , Transcriptome*/genetics , Glymphatic System*/physiology , Glymphatic System*/metabolism , Brain*/metabolism , Brain*/physiology , Organ Specificity*/genetics, Humans ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; Mendelian Randomization Analysis ; Diffusion Tensor Imaging

Development and evaluation of a novel organ-specific biomechanics-guided contrast-enhanced CT volume synthesis model ^.

Autori: Du S Shen M Liu Y a ďalší

Zdroj: Physics in medicine and biology [Phys Med Biol] 2025 Oct 28; Vol. 70 (21). Date of Electronic Publication: 2025 Oct 28.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: IOP Publishing Country of Publication: England NLM ID: 0401220 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6560 (Electronic) Linking ISSN: 00319155 NLM ISO Abbreviation: Phys Med Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tomography, X-Ray Computed*/methods , Contrast Media* , Organ Specificity*, Biomechanical Phenomena ; Humans ; Liver/diagnostic imaging ; Image Processing, Computer-Assisted/methods ; Kidney/diagnostic imaging

Endothelial c-Myc and Doxorubicin-Induced Metabolic Alterations: A Multi-Organ Optical Imaging Study.

Autori: Nategh P Neghabi M Ceyhan B a ďalší

Zdroj: Journal of biophotonics [J Biophotonics] 2025 Sep; Vol. 18 (9), pp. e70037. Date of Electronic Publication: 2025 Apr 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101318567 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1864-0648 (Electronic) Linking ISSN: 1864063X NLM ISO Abbreviation: J Biophotonics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Doxorubicin*/pharmacology , Optical Imaging* , Proto-Oncogene Proteins c-myc*/metabolism , Proto-Oncogene Proteins c-myc*/deficiency , Proto-Oncogene Proteins c-myc*/genetics , Organ Specificity*/drug effects, Animals ; Mice ; Oxidative Stress/drug effects ; Oxidation-Reduction/drug effects ; Mice, Knockout ; Kidney/metabolism ; Kidney/drug effects ; Kidney/diagnostic imaging ; Liver/metabolism ; Liver/drug effects ; Liver/diagnostic imaging

Cross-tissue multicellular coordination and its rewiring in cancer.

Autori: Shi Q Chen Y Li Y a ďalší

Zdroj: Nature [Nature] 2025 Jul; Vol. 643 (8071), pp. 529-538. Date of Electronic Publication: 2025 May 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cell Communication* , Neoplasms*/pathology , Neoplasms*/genetics , Neoplasms*/immunology , Organ Specificity* , Tumor Microenvironment*, Animals ; Female ; Humans ; Male ; Mice ; Aging/pathology ; Breast Neoplasms/pathology ; Disease Progression ; Fibroblasts/pathology ; Fibroblasts/cytology ; Single-Cell Analysis ; Spleen/cytology ; Spleen/pathology ; Spleen/immunology ; Transcriptome

The Somatic Mosaicism across Human Tissues Network.

Autori: Coorens THH Oh JW Choi YA a ďalší

Korporácia: Coorens THH Oh JW Choi YA a ďalší

Zdroj: Nature [Nature] 2025 Jul; Vol. 643 (8070), pp. 47-59. Date of Electronic Publication: 2025 Jul 02.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mosaicism* , Mutation*/genetics , Organ Specificity*/genetics, Humans ; Clone Cells/metabolism ; Clone Cells/cytology ; Phenotype ; Female ; Male ; Aging/genetics

Heterogeneous tissue-specific macrophages orchestrate metastatic organotropism of breast cancer: implications for promising therapeutics.

Autori: Wang C Fan P Zhou Y a ďalší

Zdroj: Journal of translational medicine [J Transl Med] 2025 Jun 20; Vol. 23 (1), pp. 692. Date of Electronic Publication: 2025 Jun 20.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Breast Neoplasms*/pathology , Breast Neoplasms*/therapy , Macrophages*/pathology , Macrophages*/metabolism , Organ Specificity*, Humans ; Neoplasm Metastasis ; Female ; Tumor Microenvironment ; Animals ; Signal Transduction

Investigation of cell development and tissue structure network based on natural Language processing of scRNA-seq data.

Autori: Wei S Lu Y Wang P a ďalší

Zdroj: Journal of translational medicine [J Transl Med] 2025 Mar 04; Vol. 23 (1), pp. 264. Date of Electronic Publication: 2025 Mar 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Single-Cell Analysis*/methods , Natural Language Processing* , RNA-Seq* , Sequence Analysis, RNA* , Organ Specificity*/genetics, Humans ; Gene Regulatory Networks ; Cell Differentiation/genetics ; Animals ; Single-Cell Gene Expression Analysis

From Multiple Sclerosis to Organ-Specific Autoimmune Disorders: Insights into the Molecular and Clinical Implications of Comorbidity.

Autori: Zabihi MR Zangooie A Piroozkhah M a ďalší

Zdroj: Molecular neurobiology [Mol Neurobiol] 2025 Mar; Vol. 62 (3), pp. 3396-3411. Date of Electronic Publication: 2024 Sep 17.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Multiple Sclerosis*/epidemiology , Multiple Sclerosis*/immunology , Multiple Sclerosis*/pathology , Autoimmune Diseases*/epidemiology , Autoimmune Diseases*/immunology , Autoimmune Diseases*/pathology , Organ Specificity*, Humans ; Comorbidity ; Animals

Transcriptional dynamics and tissue-specific expression patterns of transposable elements in orthopteran insects.

Autori: Majid M Liu X Khan H a ďalší

Zdroj: Gene [Gene] 2025 Feb 05; Vol. 936, pp. 149090. Date of Electronic Publication: 2024 Nov 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE

Výrazy zo slovníka MeSH: Gene Expression Regulation* , Organ Specificity*/genetics , Orthoptera*/genetics , Transcription, Genetic*, Animals ; Gene Expression Profiling ; Genetic Variation ; Genome Size ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Species Specificity ; Male ; Female

Organ-specific microenvironments drive divergent T cell evolution in acute graft-versus-host disease.

Autori: Omdahl KI Bermea RS Fleming R a ďalší

Zdroj: Science translational medicine [Sci Transl Med] 2025 Jan 29; Vol. 17 (783), pp. eads1298. Date of Electronic Publication: 2025 Jan 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Graft vs Host Disease*/immunology , Graft vs Host Disease*/genetics , Graft vs Host Disease*/pathology , T-Lymphocytes*/immunology , Organ Specificity* , Cellular Microenvironment*, Animals ; Acute Disease ; CD8-Positive T-Lymphocytes/immunology ; Lung/pathology ; Lung/immunology ; Liver/pathology ; Liver/immunology ; Hematopoietic Stem Cell Transplantation ; Single-Cell Analysis ; Gene Expression Profiling ; CX3C Chemokine Receptor 1/metabolism

miRNATissueAtlas 2025: an update to the uniformly processed and annotated human and mouse non-coding RNA tissue atlas.

Autori: Rishik S Hirsch P Grandke F a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2025 Jan 06; Vol. 53 (D1), pp. D129-D137.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Organ Specificity*/genetics, Animals ; Mice ; Humans ; Molecular Sequence Annotation ; RNA, Untranslated/genetics ; Software ; Databases, Genetic ; Databases, Nucleic Acid

Vitamin D elicits tissue-specific isoform expression in Atlantic salmon muscles.

Autori: Gorman CE McGinnity P Hulsey CD

Zdroj: BMC genomics [BMC Genomics] 2025 Nov 12; Vol. 26 (1), pp. 1031. Date of Electronic Publication: 2025 Nov 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Salmo salar*/genetics , Salmo salar*/metabolism , Vitamin D*/pharmacology , Muscles*/metabolism , Muscles*/drug effects , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/drug effects, Animals ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Alternative Splicing/drug effects ; Organ Specificity/drug effects ; Organ Specificity/genetics ; Gene Expression Profiling ; Transcriptome/drug effects ; Gene Expression Regulation/drug effects

Establishment of a liver-specific Albumin-Cre recombinase transgenic golden hamster model using gRosa26-Targeted dual-fluorescent reporter system for hepatocyte-specific genetic manipulation.

Autori: Dong M Zhang J Long L a ďalší

Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Dec 15; Vol. 792, pp. 152912. Date of Electronic Publication: 2025 Nov 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Integrases*/genetics , Integrases*/metabolism , Mesocricetus*/genetics , Hepatocytes*/metabolism , Genes, Reporter* , Liver*/metabolism , Albumins*/genetics , Albumins*/metabolism , RNA, Untranslated*/genetics, Animals ; Cricetinae ; Animals, Genetically Modified ; CRISPR-Cas Systems ; Gene Editing/methods ; Male ; Mice ; Organ Specificity

A bioinformatic survey of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data.

Autori: Page ML Aguzzoli Heberle B Brandon JA a ďalší

Zdroj: BMC genomics [BMC Genomics] 2025 Dec 05; Vol. 26 (1), pp. 1078. Date of Electronic Publication: 2025 Dec 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: RNA Isoforms*/genetics , Computational Biology*/methods, Humans ; Alternative Splicing ; Organ Specificity ; Sequence Analysis, RNA ; Molecular Sequence Annotation ; Gene Expression Profiling

Tissue-specific transcriptomic and endocrine signatures of obligatory reproductive diapause in Eurygaster integriceps.

Autori: Alborzi Z Amiri A Piulachs MD a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Dec 02; Vol. 15 (1), pp. 42999. Date of Electronic Publication: 2025 Dec 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Transcriptome* , Diapause, Insect*/genetics , Hemiptera*/genetics , Hemiptera*/physiology , Diapause*/genetics, Animals ; Reproduction/genetics ; Insect Proteins/genetics ; Insect Proteins/metabolism ; Gene Expression Profiling ; Juvenile Hormones/metabolism ; Juvenile Hormones/genetics ; Female ; Fat Body/metabolism ; Brain/metabolism ; Vitellogenins/genetics ; Vitellogenins/metabolism ; Organ Specificity

Tissue-specific transcriptome analysis in Propsilocerus akamusi provides novel insights into the regulatory mechanisms under deltamethrin exposure.

Autori: Sun X Peng Y Zhu J a ďalší

Zdroj: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101542. Date of Electronic Publication: 2025 May 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pyrethrins*/pharmacology , Pyrethrins*/toxicity , Nitriles*/pharmacology , Nitriles*/toxicity , Chironomidae*/genetics , Chironomidae*/drug effects , Chironomidae*/metabolism , Transcriptome*/drug effects , Insecticides*/pharmacology , Insecticides*/toxicity , Gene Expression Regulation*/drug effects, Animals ; Gene Expression Profiling ; Malpighian Tubules/metabolism ; Malpighian Tubules/drug effects ; Insect Proteins/genetics ; Insect Proteins/metabolism ; Organ Specificity

Phylogenetic analysis, tissue expression, and response to temperature variation of TRP genes in Monopterus albus.

Autori: Yang Z Sun Y

Zdroj: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101616. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Transient Receptor Potential Channels*/genetics , Transient Receptor Potential Channels*/metabolism , Phylogeny* , Smegmamorpha*/genetics , Fish Proteins*/genetics , Fish Proteins*/metabolism, Animals ; Temperature ; Male ; Female ; Organ Specificity

Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities.

Autori: Robles-Remacho A Zou Y Grillo M a ďalší

Zdroj: Trends in genetics : TIG [Trends Genet] 2025 Dec; Vol. 41 (12), pp. 1131-1143. Date of Electronic Publication: 2025 Jul 11.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 8507085 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0168-9525 (Print) Linking ISSN: 01689525 NLM ISO Abbreviation: Trends Genet Subsets: MEDLINE

Výrazy zo slovníka MeSH: MicroRNAs*/genetics , Gene Expression Profiling*/methods , Gene Expression Regulation* , Transcriptome*/genetics, Humans ; Animals ; Organ Specificity/genetics

Tissue-specific regulation of NO-GC isoforms in the cardiovascular system.

Autori: Giesen J Menges L Benndorf RA

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 4), pp. 117384. Date of Electronic Publication: 2025 Oct 03.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cardiovascular System*/metabolism , Cardiovascular System*/enzymology , Nitric Oxide*/metabolism , Guanylate Cyclase*/metabolism , Guanylate Cyclase*/genetics, Animals ; Humans ; Cyclic GMP/metabolism ; Cardiovascular Diseases/metabolism ; Signal Transduction/physiology ; Organ Specificity/physiology ; Isoenzymes/metabolism

Brain Region-Specific Accumulation of Amyloidosis-Associated Proteins in Postmortem Brain Tissues of Alzheimer's Disease Patients.

Autori: Tsering W Philips JL Golde TE a ďalší

Zdroj: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 15759-15778. Date of Electronic Publication: 2025 Jul 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Brain*/metabolism , Brain*/pathology , Amyloidosis*/metabolism , Amyloidosis*/pathology , Extracellular Matrix Proteins*/metabolism, Humans ; Female ; Male ; Aged ; Aged, 80 and over ; Plaque, Amyloid/pathology ; Plaque, Amyloid/metabolism ; Neurofibrillary Tangles/metabolism ; Neurofibrillary Tangles/pathology ; Autopsy ; tau Proteins/metabolism ; Organ Specificity ; Amyloid beta-Peptides/metabolism