Search Results - "Optogenetics methods"

Dentate gyrus is needed for memory retrieval

Authors: Alejandro Carretero-Guillén Mario Treviño María Ángeles Gómez-Climent et al.

Source: Mol Psychiatry
Carretero-Guillén, Alejandro Treviño, M Gómez Climent, María Ángeles Dogbevia, GK Bertocchi, I Sprengel, R Larkum, ME Vlachos, A Gruart, A Delgado-García, JM Hasan, MT 2024 Dentate gyrus is needed for memory retrieval. Molecular Psychiatry 29 2939 2950
RODERIC. Repositorio Institucional de la Universitat de València
instname
Molecular Psychiatry

Subject Terms: Neurons, Male, 0301 basic medicine, 0303 health sciences, Hippocampus, Article, Optogenetics, 03 medical and health sciences, Memory, Dentate Gyrus, Mental Recall, Animals, Mental Recall/physiology [MeSH], Mental Recall/drug effects [MeSH], Optogenetics/methods [MeSH], Neurons/metabolism [MeSH], 42/41, 42, Animals [MeSH], Dentate Gyrus/physiology [MeSH], Memory/physiology [MeSH], Male [MeSH], Neurons/physiology [MeSH], 692/699, Clozapine/analogs, 96/44, 9/30, Hippocampus/physiology [MeSH], Rabbits [MeSH], Dentate Gyrus/drug effects [MeSH], Clozapine/pharmacology [MeSH], 631/378, Hippocampus/metabolism [MeSH], article, Rabbits, Clozapine

File Description: application/pdf; pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38609585
https://hdl.handle.net/10550/106523
http://hdl.handle.net/21.11116/0000-000F-4677-D
http://hdl.handle.net/21.11116/0000-000F-4679-B
http://hdl.handle.net/21.11116/0000-000F-467A-A
https://repository.publisso.de/resource/frl:6501140
https://hdl.handle.net/2318/1971250
https://doi.org/10.1038/s41380-024-02546-0

Speed up Your Cell Line Development

Authors: Ningaloo Biosystems

Subject Terms: Optogenetics, Bioreactors, Optogenetics/methods, Synthetic Biology, Cell Culture Techniques/trends

Dual-color optical activation and suppression of neurons with high temporal precision

Authors: Mermet-Joret, Noëmie Moreno, Andrea Zbela, Agnieszka et al.

Source: Mermet-Joret , N , Moreno , A , Zbela , A , Nazari , M , Ellendersen , B E , Baro , R C , Krauth , N , von Philipsborn , A , Sørensen , A T , Piriz , J , Lin , J Y-L & Nabavi , S 2025 , ' Dual-color optical activation and suppression of neurons with high temporal precision ' , eLife , vol. 12 , RP90327 . https://doi.org/10.7554/eLife.90327.3

Subject Terms: Optogenetics/methods, Animals, Neurons/physiology, Action Potentials/radiation effects, Light, Color, Hippocampus/physiology, Mice, Channelrhodopsins/metabolism

File Description: application/pdf

Availability: https://researchprofiles.ku.dk/da/publications/21d36d4f-2ef2-439d-a25b-43a7745814b9
https://doi.org/10.7554/eLife.90327.3
https://curis.ku.dk/ws/files/457086869/elife-90327-v1.pdf

Acute Optogenetic Stimulation of Serotonin Neurons Reduces Cell Proliferation in the Dentate Gyrus of Mice

Authors: Araragi, Naozumi Petermann, Markus Suzuki, Mototaka et al.

Source: Araragi, N, Petermann, M, Suzuki, M, Larkum, M, Mosienko, V, Bader, M, Alenina, N & Klempin, F 2025, 'Acute Optogenetic Stimulation of Serotonin Neurons Reduces Cell Proliferation in the Dentate Gyrus of Mice', ACS Chemical Neuroscience, vol. 16, no. 5, pp. 781-789. https://doi.org/10.1021/acschemneuro.4c00771

Subject Terms: Animals, Dentate Gyrus/metabolism, Optogenetics/methods, Cell Proliferation/physiology, Mice, Transgenic, Serotonergic Neurons/physiology, Tryptophan Hydroxylase/metabolism, Neurogenesis/physiology, Serotonin/metabolism, Male, Channelrhodopsins/metabolism, Raphe Nuclei/metabolism

Availability: https://hdl.handle.net/1983/fd688218-4954-4ecd-9185-62fb6ccf3979
https://research-information.bris.ac.uk/en/publications/fd688218-4954-4ecd-9185-62fb6ccf3979
https://doi.org/10.1021/acschemneuro.4c00771

Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments

Authors: Milena Pasolli Joyce C. M. Meiring James P. Conboy et al.

Source: J Cell Biol

Subject Terms: Tools, Microtubules/metabolism, Intermediate Filaments/metabolism, Vimentin/metabolism, Mitochondria/metabolism, Optogenetics/methods, Animals, Humans, Endoplasmic Reticulum/metabolism, HeLa Cells

From resonance to chaos: modulating spatiotemporal patterns through a synthetic optogenetic oscillator

Authors: Jung Hun Park Gábor Holló Yolanda Schaerli

Source: Nat Commun
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Nature communications, vol. 15, no. 1, pp. 7284

Subject Terms: Optogenetics, Light, Nonlinear Dynamics, Biological Clocks, Science, Optogenetics/methods, Escherichia coli/genetics, Models, Theoretical, Escherichia coli, Article

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39179558
https://doaj.org/article/90d53740d35e4244ba4f860144d3bd90
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_31414E598D6E1
https://serval.unil.ch/resource/serval:BIB_31414E598D6E.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_31414E598D6E

From resonance to chaos by modulating spatiotemporal patterns through a synthetic optogenetic oscillator.

Authors: Park, J.H. Holló, G. Schaerli, Y.

Source: Nature communications, vol. 15, no. 1, pp. 7284

Subject Terms: Optogenetics/methods, Escherichia coli/genetics, Biological Clocks, Light, Nonlinear Dynamics, Models, Theoretical

File Description: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/39179558; info:eu-repo/semantics/altIdentifier/eissn/2041-1723; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_31414E598D6E1; https://serval.unil.ch/notice/serval:BIB_31414E598D6E; https://serval.unil.ch/resource/serval:BIB_31414E598D6E.P001/REF.pdf

Availability: https://serval.unil.ch/notice/serval:BIB_31414E598D6E
https://doi.org/10.1038/s41467-024-51626-w
https://serval.unil.ch/resource/serval:BIB_31414E598D6E.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_31414E598D6E1

Combined-electrical optogenetic stimulation but not channelrhodopsin kinetics improves the fidelity of high rate stimulation in the auditory pathway in mice

Authors: Ajay, Elise A Thompson, Alex C Azees, Ajmal A et al.

Source: Ajay, E A, Thompson, A C, Azees, A A, Wise, A K, Grayden, D B, Fallon, J B & Richardson, R T 2024, 'Combined-electrical optogenetic stimulation but not channelrhodopsin kinetics improves the fidelity of high rate stimulation in the auditory pathway in mice', Scientific Reports, vol. 14, 21028, pp. 21028. https://doi.org/10.1038/s41598-024-71712-9

Subject Terms: Animals, Optogenetics/methods, Mice, Auditory Pathways/physiology, Channelrhodopsins/metabolism, Electric Stimulation/methods, Inferior Colliculi/physiology, Cochlear Nerve/physiology, Kinetics, Cochlear Implants

Availability: https://hdl.handle.net/1983/3aaf9720-6030-49c0-89c9-5bab2b961a38
https://research-information.bris.ac.uk/en/publications/3aaf9720-6030-49c0-89c9-5bab2b961a38
https://doi.org/10.1038/s41598-024-71712-9

Imaging and optogenetic modulation of vascular mural cells in the live brain

Authors: Jaime Grutzendler Peng Yuan Katie N. Murray et al.

Source: Tong, L, Hill, R A, Damisah, E C, Murray, K N, Yuan, P, Bordey, A & Grutzendler, J 2021, 'Imaging and optogenetic modulation of vascular mural cells in the live brain', Nature protocols, vol. 16, no. 1, pp. 472-496. https://doi.org/10.1038/s41596-020-00425-w

Subject Terms: Male, 0301 basic medicine, Myocytes, Myocytes, Smooth Muscle, Optical Imaging, Brain, Myocytes, Smooth Muscle/cytology, Mice, Transgenic, Brain/blood supply, 01 natural sciences, Transgenic, Optical Imaging/methods, 0104 chemical sciences, 3. Good health, Optogenetics, Mice, 03 medical and health sciences, Smooth Muscle/cytology, Pericytes/cytology, Blood Circulation, Optogenetics/methods, Animals, Female, Pericytes

Access URL: https://pubmed.ncbi.nlm.nih.gov/33299155
https://www.nature.com/articles/s41596-020-00425-w.pdf
https://www.nature.com/articles/s41596-020-00425-w
https://pubmed.ncbi.nlm.nih.gov/33299155/
https://www.ncbi.nlm.nih.gov/pubmed/33299155
https://www.scilit.net/article/6e733aed99faa336f0db242e995f2e42?action=show-references
http://europepmc.org/article/MED/33299155

Towards the clinical translation of optogenetic skeletal muscle stimulation

Authors: Gundelach, Lili A. Hüser, Marc A. Beutner, Dirk et al.

Contributors: Gundelach, Lili A. Hüser, Marc A. Beutner, Dirk et al.

Source: Pflugers Arch

Subject Terms: 2. Zero hunger, 0301 basic medicine, 0303 health sciences, Invited Review, Electric Stimulation Therapy, 3. Good health, Optogenetics, Translational Research, Biomedical, 03 medical and health sciences, Animals, Humans, Translational Medical Research/methods [MeSH], Immune response, Optogenetics/methods [MeSH], Muscle, Skeletal/physiology [MeSH], Humans [MeSH], Gene transfer, Electric Stimulation Therapy/methods [MeSH], Animals [MeSH], Optical implants, Optogenetic stimulation, Electrical stimulation, Muscle Contraction [MeSH], Muscle, Skeletal/metabolism [MeSH], Skeletal muscle, Muscle, Skeletal, Muscle Contraction

File Description: pdf

Access URL: https://link.springer.com/content/pdf/10.1007/s00424-020-02387-0.pdf
https://pubmed.ncbi.nlm.nih.gov/32415463
https://link.springer.com/article/10.1007/s00424-020-02387-0
https://pubmed.ncbi.nlm.nih.gov/32415463/
https://link.springer.com/content/pdf/10.1007/s00424-020-02387-0.pdf
https://www.scilit.net/article/c98fc7aad7c758be10fc143ac5c27487
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239821
https://resolver.sub.uni-goettingen.de/purl?gro-2/82100
https://repository.publisso.de/resource/frl:6467264

Spread of activation and interaction between channels with multi-channel optogenetic stimulation in the mouse cochlea

Authors: Azees, Ajmal A Thompson, Alex C. Thomas, Ross et al.

Source: Azees, A A, Thompson, A C, Thomas, R, Zhou, J, Ruther, P, Wise, A K, Ajay, E A, Garrett, D J, Quigley, A, Fallon, J B & Richardson, R T 2023, 'Spread of activation and interaction between channels with multi-channel optogenetic stimulation in the mouse cochlea', Hearing Research, vol. 440, 108911. https://doi.org/10.1016/j.heares.2023.108911

Subject Terms: Mice, Animals, Optogenetics/methods, Cochlea/physiology, Cochlear Implants, Cochlear Implantation, Opsins/genetics, Electric Stimulation, Deafness/therapy

Availability: https://hdl.handle.net/1983/d927a9f0-0791-47ca-b00f-7ca3c1181010
https://research-information.bris.ac.uk/en/publications/d927a9f0-0791-47ca-b00f-7ca3c1181010
https://doi.org/10.1016/j.heares.2023.108911

The role of microglia membrane potential in chemotaxis

Authors: Laprell, Laura Schulze, Christian Brehme, Marie-Luise et al.

Source: http://lobid.org/resources/99370676031606441#!, 18(1):21.

Subject Terms: Two-photon microscopy, Calcium Signaling/physiology [MeSH], Microscopy, Fluorescence, Multiphoton/methods [MeSH], Laser damage, Chemotaxis/physiology [MeSH], Mice, Transgenic [MeSH], Male [MeSH], Chemotaxis, Hippocampus/physiology [MeSH], Microglia/chemistry [MeSH], Calcium signaling, Optogenetics, Short Report, Female [MeSH], Optogenetics/methods [MeSH], Hippocampus, Microglia/physiology [MeSH], Microglia, Membrane Potentials/physiology [MeSH], Animals [MeSH], Mice [MeSH], Channelrhodopsin, Hippocampus/cytology [MeSH], Organ Culture Techniques [MeSH], Hippocampus/chemistry [MeSH], Sterile inflammation

Relation: https://repository.publisso.de/resource/frl:6465794; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798195/

Availability: https://repository.publisso.de/resource/frl:6465794
https://doi.org/10.1186/s12974-020-02048-0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7798195/

Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics

Contributors: Choong Yeon Kim Min Jeong Ku Raza Qazi et al.

Subject Terms: Animals, Brain / physiology, Deep Brain Stimulation / methods, Electrodes, Implanted, Electromagnetic Phenomena, Humans, Locomotion / physiology, Male, Optogenetics / instrumentation, Optogenetics / methods, Rats, Sprague-Dawley, Wireless Technology

Relation: NATURE COMMUNICATIONS; J02293; https://ir.ymlib.yonsei.ac.kr/handle/22282913/182051; T202100294

Availability: https://ir.ymlib.yonsei.ac.kr/handle/22282913/182051
https://doi.org/10.1038/s41467-020-20803-y

SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity

Authors: Oldani, Silvia Moreno-Velasquez, Laura Faiss, Lukas et al.

Source: Journal of neurochemistry 156(3), 324 - 336 (2021). doi:10.1111/jnc.15210

Subject Terms: info:eu-repo/classification/ddc/610, Animals, Brain: physiology, Female, Long-Term Potentiation: physiology, Male, Mice, Inbred C57BL, Optogenetics: methods, Rats, Wistar

Subject Geographic: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:33037623; info:eu-repo/semantics/altIdentifier/issn/0022-3042; info:eu-repo/semantics/altIdentifier/issn/1471-4159; https://pub.dzne.de/record/154191

Availability: https://pub.dzne.de/record/154191
https://pub.dzne.de/search?p=id:%22DZNE-2021-00053%22

Dual-color optical activation and suppression of neurons with high temporal precision

Authors: John Y. Lin Noëmie Mermet-Joret Ellendersen Be et al.

Source: eLife
eLife, Vol 12 (2025)
Mermet-Joret, N, Moreno, A, Zbela, A, Nazari, M, Ellendersen, B E, Baro, R C, Krauth, N, von Philipsborn, A, Sørensen, A T, Piriz, J, Lin, J Y-L & Nabavi, S 2025, ' Dual-color optical activation and suppression of neurons with high temporal precision ', eLife, vol. 12, RP90327 . https://doi.org/10.7554/eLife.90327.3

Subject Terms: Channelrhodopsins/metabolism, 0301 basic medicine, Light, QH301-705.5, Science, Action Potentials, Color, Hippocampus, Mice, 03 medical and health sciences, channelrhodopsin, Channelrhodopsins, Animals, Biology (General), Hippocampus/physiology, optogenetics, Neurons, 0303 health sciences, membrane channels, Optogenetics, Optogenetics/methods, Action Potentials/radiation effects, Medicine, Neurons/physiology, mutagenesis, Neuroscience

File Description: application/pdf

Access URL: https://www.biorxiv.org/content/biorxiv/early/2021/05/06/2021.05.05.442824.full.pdf
https://pubmed.ncbi.nlm.nih.gov/40357795
https://doaj.org/article/332a00d1399646e6ac658b5c7ebd82f6
https://www.biorxiv.org/content/10.1101/2021.05.05.442824v1
https://www.biorxiv.org/content/biorxiv/early/2021/05/06/2021.05.05.442824.full.pdf
https://europepmc.org/article/PPR/PPR334897
https://curis.ku.dk/ws/files/457086869/elife-90327-v1.pdf

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain

Authors: Hyung Bae Kwon Meaghan C. Creed Christian Lüscher et al.

Source: Nature Methods, Vol. 14, No 5 (2017) pp. 495-503

Subject Terms: 0301 basic medicine, 616.8, Light, Dopamine, Neurons/metabolism, Gene Expression, Signal-To-Noise Ratio, Ligands, Mice, 03 medical and health sciences, Animal/physiology, Neural Pathways/physiology, Dopamine D2/genetics, Brain/cytology/metabolism, Brain Mapping/methods, Endopeptidases/genetics, Receptors, Endopeptidases, Neural Pathways, Animals, Humans, Neurons, Behavior, Brain Mapping, 0303 health sciences, Behavior, Animal, Receptors, Dopamine D2, Brain, ddc:616.8, Rats, 3. Good health, Optogenetics, HEK293 Cells, Gene Expression/drug effects/radiation effects, Optogenetics/methods, Dopamine/metabolism/pharmacology, Photic Stimulation

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/28369042
https://archive-ouverte.unige.ch/unige:100750
https://koreauniv.pure.elsevier.com/en/publications/temporally-precise-labeling-and-control-of-neuromodulatory-circui
https://nature.com/articles/nmeth.4234
https://europepmc.org/article/MED/28369042
https://core.ac.uk/display/86629935
https://pure.mpg.de/pubman/faces/ViewItemOverviewPage.jsp?itemId=item_3071248
https://archive-ouverte.unige.ch/unige:100750
https://doi.org/10.1038/nmeth.4234
https://archive-ouverte.unige.ch/unige:100750

Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors.

Authors: Anpilov, Sergey Shemesh, Yair Eren, Noa et al.

Source: Neuron, 107 (4), 644-655.e7 (2020)

Subject Terms: Agonistic Behavior/physiology, Animals, Behavior, Animal/physiology, Mice, Neurons/metabolism/physiology, Optogenetics/methods, Oxytocin/metabolism, Social Behavior, Wireless Technology, aggression, optogenetics, oxytocin, social salience, wireless, Life sciences, Anatomy (cytology, histology, embryology.) & physiology, Sciences du vivant, Anatomie (cytologie, histologie, embryologie.) & physiologie

Relation: urn:issn:0896-6273; urn:issn:1097-4199; https://orbi.uliege.be/handle/2268/260515; info:hdl:2268/260515; https://orbi.uliege.be/bitstream/2268/260515/1/Wireless_Optogenetic_Stimulation_of_Oxytocin_Neuro.pdf; info:pmid:32544386

Availability: https://orbi.uliege.be/handle/2268/260515
https://orbi.uliege.be/bitstream/2268/260515/1/Wireless_Optogenetic_Stimulation_of_Oxytocin_Neuro.pdf
https://doi.org/10.1016/j.neuron.2020.05.028

Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects

Authors: Müller-Komorowska, Daniel Opitz, Thoralf Elzoheiry, Shehabeldin et al.

Source: Frontiers in neural circuits 14, 16 (2020). doi:10.3389/fncir.2020.00016

Subject Terms: info:eu-repo/classification/ddc/610, Animals, CA3 Region, Hippocampal: chemistry, Hippocampal: cytology, Hippocampal: metabolism, Gene Expression, Integrases: analysis, Integrases: biosynthesis, Integrases: genetics, Interneurons: chemistry, Interneurons: metabolism, Mice, Inbred C57BL, Transgenic, Optogenetics: methods, Somatostatin: analysis, Somatostatin: biosynthesis, Somatostatin: genetics

Subject Geographic: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1662-5110; info:eu-repo/semantics/altIdentifier/pmid/pmid:32395103; https://pub.dzne.de/record/151549

Availability: https://pub.dzne.de/record/151549
https://pub.dzne.de/search?p=id:%22DZNE-2020-01133%22

Optogenetic approaches to treat epilepsy

Authors: Wykes, Robert C Kullmann, Dimitri M Pavlov, Ivan et al.

Source: Wykes, R C, Kullmann, D M, Pavlov, I & Magloire, V 2016, 'Optogenetic approaches to treat epilepsy', Journal of Neuroscience Methods, vol. 260, pp. 215-20. https://doi.org/10.1016/j.jneumeth.2015.06.004

Subject Terms: 0301 basic medicine, 0303 health sciences, Epilepsy, Opsins, Opsins/genetics, Nerve Tissue Proteins, Genetic Therapy, 3. Good health, Optogenetics, Disease Models, Animal, 03 medical and health sciences, Treatment Outcome, Epilepsy/physiopathology, Optogenetics/methods, Nerve Tissue Proteins/genetics, Animals, Genetic Therapy/methods

Access URL: https://pubmed.ncbi.nlm.nih.gov/26072246
https://www.sciencedirect.com/science/article/pii/S0165027015002216
https://pubmed.ncbi.nlm.nih.gov/26072246/
https://www.ncbi.nlm.nih.gov/pubmed/26072246
https://europepmc.org/article/MED/26072246
https://www.research.manchester.ac.uk/portal/en/publications/optogenetic-approaches-to-treat-epilepsy(ee87c643-6f4f-48e3-8b66-cfc0d89c6f65)/export.html
http://www.sciencedirect.com/science/article/pii/S0165027015002216
https://research.manchester.ac.uk/en/publications/ee87c643-6f4f-48e3-8b66-cfc0d89c6f65
https://doi.org/10.1016/j.jneumeth.2015.06.004

Multiplexed temporally focused light shaping through a gradient index lens for precise in-depth optogenetic photostimulation

Authors: Emiliano Ronzitti I-Wen Chen Eirini Papagiakoumou et al.

Contributors: Emiliano Ronzitti I-Wen Chen Eirini Papagiakoumou et al.

Source: Sci Rep
Scientific Reports

Subject Terms: Male, Neurons, 0301 basic medicine, Photons, Brain, Lens, Crystalline / physiology, 7. Clean energy, Article, Neurons / physiology, Optogenetics, Mice, 03 medical and health sciences, [SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging, Optogenetics / methods, Lens, Crystalline, Brain / physiology, Animals, Female, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Lenses

File Description: application/pdf

Access URL: https://www.nature.com/articles/s41598-019-43933-w.pdf
https://pubmed.ncbi.nlm.nih.gov/31110187
https://www.nature.com/articles/s41598-019-43933-w
https://pubmed.ncbi.nlm.nih.gov/31110187/
https://www.nature.com/articles/s41598-019-43933-w.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527563
http://ui.adsabs.harvard.edu/abs/2019NatSR...9.7603A/abstract
https://europepmc.org/article/PPR/PPR67016