Suchergebnisse - "Ophthalmic Solutions"

Development of a sustainable fluorescence-based approach using erythrosine B dye for nanolevel quantification of bepotastine in eye drops and aqueous humor.

Autoren: Al-Farhan BS Saleh SF Ibrahim AMM et al.

Quelle: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Dec 15; Vol. 343, pp. 126457. Date of Electronic Publication: 2025 May 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

MeSH-Schlagworte: Erythrosine*/chemistry , Fluorescent Dyes*/chemistry , Ophthalmic Solutions*/analysis , Ophthalmic Solutions*/chemistry , Piperidines*/analysis, Spectrometry, Fluorescence/methods ; Limit of Detection ; Reproducibility of Results ; Humans ; Green Chemistry Technology

Evaluation of umbilical cord blood serum eye drops for severe dry eye in two distinct populations-Sjögren's syndrome and mustard gas-induced ocular injury: Protocol for a pilot randomized clinical trial.

Autoren: Daryabari SH Aghamollaei H Hosseini Imeni SM et al.

Quelle: PloS one [PLoS One] 2025 Dec 04; Vol. 20 (12), pp. e0337186. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).

Publikationsart: Journal Article; Clinical Trial Protocol

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Ophthalmic Solutions*/therapeutic use , Ophthalmic Solutions*/administration & dosage , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/chemically induced , Sjogren's Syndrome*/therapy , Sjogren's Syndrome*/drug therapy , Mustard Gas*/toxicity , Mustard Gas*/adverse effects , Fetal Blood* , Serum*, Humans ; Pilot Projects ; Male ; Female ; Adult ; Tears ; Chemical Warfare Agents/toxicity ; Middle Aged ; Randomized Controlled Trials as Topic

Safety and pharmacokinetics of escalating doses of recombinant human nerve growth factor eye drops (HT006.2.2) in healthy subjects.

Autoren: Dai Y Wu F Pang H et al.

Quelle: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 Dec 01; Vol. 215, pp. 107314. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Ophthalmic Solutions*/pharmacokinetics , Ophthalmic Solutions*/administration & dosage , Ophthalmic Solutions*/adverse effects , Nerve Growth Factor*/pharmacokinetics , Nerve Growth Factor*/administration & dosage , Nerve Growth Factor*/adverse effects, Humans ; Male ; Adult ; Young Adult ; Female ; Healthy Volunteers ; Recombinant Proteins/pharmacokinetics ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/adverse effects ; Tears/metabolism ; Dose-Response Relationship, Drug ; Double-Blind Method ; Middle Aged

Determination of ethylene oxide residues in sterilized ophthalmic active pharmaceutical ingredients via the full evaporation technique coupled to gas chromatography.

Autoren: Rehman IU Wolfs K Haghedooren E et al.

Quelle: Talanta [Talanta] 2025 Dec 01; Vol. 295, pp. 128335. Date of Electronic Publication: 2025 May 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE

MeSH-Schlagworte: Ethylene Oxide*/analysis , Ophthalmic Solutions*/chemistry , Ophthalmic Solutions*/analysis, Chromatography, Gas/methods ; Sterilization ; Limit of Detection ; Bulk Drugs

Endothelia-targeting eye drops deliver a STING inhibitor to effectively reduce retinal neovascularization in ischemic retinopathy.

Autoren: Wen S He X Wang J et al.

Quelle: Biomaterials [Biomaterials] 2025 Dec; Vol. 323, pp. 123424. Date of Electronic Publication: 2025 May 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

MeSH-Schlagworte: Retinal Neovascularization*/drug therapy , Retinal Neovascularization*/pathology , Retinal Neovascularization*/complications , Ophthalmic Solutions*/administration & dosage , Ophthalmic Solutions*/therapeutic use , Membrane Proteins*/antagonists & inhibitors , Membrane Proteins*/metabolism , Ischemia*/complications , Ischemia*/drug therapy , Ischemia*/pathology, Animals ; Mice, Inbred C57BL ; Mice ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Humans ; Nanoparticles/chemistry ; Male ; Retina/pathology ; Retina/drug effects

Allogeneic Umbilical Cord Blood Serum Eyedrops for the Treatment of Severe Dry Eye Disease Patients.

Autoren: Zeppieri M Gagliano G Capobianco M et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 06; Vol. 26 (21). Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/etiology , Ophthalmic Solutions*/therapeutic use , Ophthalmic Solutions*/administration & dosage , Fetal Blood* , Serum*, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Aged, 80 and over ; Adolescent ; Young Adult ; Retrospective Studies ; Treatment Outcome ; Graft vs Host Disease

Spectroscopic quantification of cyclopentolate using an erythrosine-based resonance rayleigh scattering strategy: application to ophthalmic formulations.

Autoren: Abu-Hassan AA; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt. Ahmedabuhassan@azhar.edu.eg.

Quelle: Scientific reports [Sci Rep] 2025 Oct 27; Vol. 15 (1), pp. 37353. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Ophthalmic Solutions*/chemistry , Ophthalmic Solutions*/analysis , Cyclopentolate*/analysis , Cyclopentolate*/chemistry , Erythrosine*/chemistry, Spectrometry, Fluorescence/methods ; Limit of Detection ; Scattering, Radiation

Amorphous layered double hydroxide-based nano-enzyme eye drops against dry eye disease by inhibiting mitochondrial damage and pyroptosis.

Autoren: Chu D Hu T Cui H et al.

Quelle: Journal of nanobiotechnology [J Nanobiotechnology] 2025 Oct 22; Vol. 23 (1), pp. 688. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE

MeSH-Schlagworte: Pyroptosis*/drug effects , Hydroxides*/chemistry , Hydroxides*/pharmacology , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/metabolism , Mitochondria*/drug effects , Mitochondria*/metabolism , Ophthalmic Solutions*/pharmacology , Ophthalmic Solutions*/chemistry, Animals ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Reactive Oxygen Species/metabolism ; Mice, Inbred C57BL ; Caspase 1/metabolism ; Humans ; Inflammasomes/metabolism ; Male

Effect of silver nitrate solution on corneal epithelial barrier function in rabbits.

Autoren: Fukuda M Kiyoi T Takeda S et al.

Quelle: Cutaneous and ocular toxicology [Cutan Ocul Toxicol] 2025 Dec; Vol. 44 (4), pp. 536-543. Date of Electronic Publication: 2025 Nov 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101266892 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-9535 (Electronic) Linking ISSN: 15569527 NLM ISO Abbreviation: Cutan Ocul Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Silver Nitrate*/toxicity , Epithelium, Corneal*/drug effects , Epithelium, Corneal*/metabolism , Preservatives, Pharmaceutical*/toxicity , Ophthalmic Solutions* , Polyphosphates*/toxicity, Animals ; Rabbits ; Zonula Occludens-1 Protein/metabolism ; Male ; Electric Impedance ; Uracil Nucleotides

Persistence with topical glaucoma therapy in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data.

Autoren: Kabeya K Satoh H Yanagi N et al.

Quelle: BMC ophthalmology [BMC Ophthalmol] 2025 Nov 28; Vol. 25 (1), pp. 676. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415 (Electronic) Linking ISSN: 14712415 NLM ISO Abbreviation: BMC Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Ophthalmic Solutions*/administration & dosage , Glaucoma*/drug therapy , Glaucoma*/epidemiology , Antihypertensive Agents*/administration & dosage , Intraocular Pressure*/drug effects, Humans ; Female ; Male ; Japan/epidemiology ; Middle Aged ; Aged ; Adult ; Retrospective Studies ; Insurance Claim Review/statistics & numerical data ; Aged, 80 and over ; Administration, Topical ; Young Adult

Corneal retention using a nanorobot-based eyedrop.

Autoren: Wan C Tian G Wang M et al.

Quelle: Journal of materials chemistry. B [J Mater Chem B] 2025 Nov 26; Vol. 13 (46), pp. 15038-15046. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-7518 (Electronic) Linking ISSN: 2050750X NLM ISO Abbreviation: J Mater Chem B Subsets: MEDLINE

MeSH-Schlagworte: Cornea*/drug effects , Cornea*/metabolism , Nanoparticles*/chemistry , Keratitis*/drug therapy , Ophthalmic Solutions*/chemistry, Animals ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Mice ; Humans ; Drug Delivery Systems ; Particle Size

Hydrogel-based ocular drug delivery systems.

Autoren: Sabbagh F Zargarian SS Kosik-Kozioł A et al.

Quelle: Journal of materials chemistry. B [J Mater Chem B] 2025 Nov 26; Vol. 13 (46), pp. 14982-15006. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-7518 (Electronic) Linking ISSN: 2050750X NLM ISO Abbreviation: J Mater Chem B Subsets: MEDLINE

MeSH-Schlagworte: Hydrogels*/chemistry , Drug Delivery Systems* , Ophthalmic Solutions*/chemistry, Humans ; Animals

Different formulations of corticosteroid eye drops at different treatment times in the control of inflammation and prevention of cystoid macular edema after cataract surgery: randomized clinical trial.

Autoren: Feitosa AM Albano MCF Lopes SP et al.

Quelle: Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2025 Nov 21; Vol. 89 (1), pp. e20250097. Date of Electronic Publication: 2025 Nov 21 (Print Publication: 2025).

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Conselho Brasileiro de Oftalmologia Country of Publication: Brazil NLM ID: 0400645 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2925 (Electronic) Linking ISSN: 00042749 NLM ISO Abbreviation: Arq Bras Oftalmol Subsets: MEDLINE

MeSH-Schlagworte: Cataract Extraction*/adverse effects , Ophthalmic Solutions*/administration & dosage , Macular Edema*/prevention & control , Macular Edema*/etiology , Dexamethasone*/administration & dosage , Glucocorticoids*/administration & dosage , Anti-Inflammatory Agents*/administration & dosage , Postoperative Complications*/prevention & control, Humans ; Male ; Female ; Aged ; Prednisolone/analogs & derivatives ; Prednisolone/administration & dosage ; Middle Aged ; Treatment Outcome ; Loteprednol Etabonate/administration & dosage ; Time Factors ; Visual Acuity/drug effects ; Intraocular Pressure/drug effects ; Inflammation/drug therapy ; Inflammation/prevention & control

Efficacy of Insulin Eye Drops in the Treatment of Corneal Ulcers in Patients with Facial Nerve Palsy and Lagophthalmos: A Retrospective Case-Control Study.

Autoren: Jelić Vuković M Matić S Biuk D et al.

Quelle: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2025 Nov 06; Vol. 61 (11). Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE

MeSH-Schlagworte: Corneal Ulcer*/drug therapy , Insulin*/therapeutic use , Insulin*/administration & dosage , Insulin*/pharmacology , Ophthalmic Solutions*/therapeutic use , Facial Paralysis*/complications , Facial Paralysis*/drug therapy , Eyelid Diseases*/complications, Humans ; Retrospective Studies ; Male ; Female ; Case-Control Studies ; Middle Aged ; Aged ; Adult ; Treatment Outcome ; Lagophthalmos

Custom-Made Injector for Suprachoroidal Ocular Delivery: Effect of Intraocular Pressure, Volume, and Location on the Distribution of Aqueous Solutions in Rabbits.

Autoren: Nork TM Katz AW Rasmussen CA et al.

Quelle: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics [J Ocul Pharmacol Ther] 2025 Nov; Vol. 41 (9), pp. 544-553. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Ocular Pharmacology And Therapeutics Country of Publication: United States NLM ID: 9511091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7732 (Electronic) Linking ISSN: 10807683 NLM ISO Abbreviation: J Ocul Pharmacol Ther Subsets: MEDLINE

MeSH-Schlagworte: Intraocular Pressure*/physiology , Intraocular Pressure*/drug effects , Choroid*/metabolism , Drug Delivery Systems*/methods , Drug Delivery Systems*/instrumentation , Ophthalmic Solutions*/administration & dosage, Animals ; Rabbits ; Injections, Intraocular/instrumentation ; Injections, Intraocular/methods ; Indocyanine Green/administration & dosage ; Fluorescein/administration & dosage

Temporal Changes in Tear Film Stability With Four Dry Eye Eyedrops in Healthy Subjects.

Autoren: Suzutani M Maehara H Koh S et al.

Quelle: Eye & contact lens [Eye Contact Lens] 2025 Nov 01; Vol. 51 (11), pp. 512-516. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101160941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-233X (Electronic) Linking ISSN: 15422321 NLM ISO Abbreviation: Eye Contact Lens Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Tears*/drug effects , Uracil Nucleotides*/administration & dosage , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/metabolism , Polyphosphates*/administration & dosage , Ophthalmic Solutions*/administration & dosage , Lubricant Eye Drops*/administration & dosage, Humans ; Male ; Female ; Adult ; Healthy Volunteers ; Young Adult ; Quinolones/administration & dosage ; Middle Aged ; Alanine/analogs & derivatives

OTC: Over the Counter, or Open to Contamination? A Review of Over-the-Counter Lubricating Eye Drops Safety.

Autoren: Kim SY Xu K Steinemann TL

Quelle: Eye & contact lens [Eye Contact Lens] 2025 Nov 01; Vol. 51 (11), pp. 517-524. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101160941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-233X (Electronic) Linking ISSN: 15422321 NLM ISO Abbreviation: Eye Contact Lens Subsets: MEDLINE

MeSH-Schlagworte: Nonprescription Drugs*/standards , Lubricant Eye Drops*/standards , Drug Contamination* , Ophthalmic Solutions*/standards, Humans ; United States ; United States Food and Drug Administration ; Dry Eye Syndromes/drug therapy

Investigation of 2,4 Di-tert-butylphenol Leaching from Multidose Ophthalmic Devices into Tacrolimus Micellar Formulations.

Autoren: Barrieu M Chennell P Mailhot-Jensen B et al.

Quelle: The AAPS journal [AAPS J] 2025 Oct 15; Vol. 27 (6), pp. 164. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

MeSH-Schlagworte: Tacrolimus*/chemistry , Tacrolimus*/administration & dosage , Phenols*/chemistry , Ophthalmic Solutions*/chemistry, Micelles ; Chemistry, Pharmaceutical ; Ethanol/chemistry ; Administration, Ophthalmic

Efficacy of povidone and propylene glycol-based artificial tears in the treatment of dry eye disease.

Autoren: Santos LCD Affonso A Belfort R Jr et al.

Quelle: Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2025 Oct 10; Vol. 88 (6), pp. e20250153. Date of Electronic Publication: 2025 Oct 10 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Conselho Brasileiro de Oftalmologia Country of Publication: Brazil NLM ID: 0400645 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2925 (Electronic) Linking ISSN: 00042749 NLM ISO Abbreviation: Arq Bras Oftalmol Subsets: MEDLINE

MeSH-Schlagworte: Propylene Glycol*/therapeutic use , Propylene Glycol*/administration & dosage , Dry Eye Syndromes*/drug therapy , Lubricant Eye Drops*/therapeutic use , Lubricant Eye Drops*/administration & dosage , Povidone-Iodine*/therapeutic use , Povidone-Iodine*/administration & dosage , Ophthalmic Solutions*/therapeutic use, Humans ; Male ; Female ; Prospective Studies ; Middle Aged ; Treatment Outcome ; Adult ; Aged ; Tears/drug effects ; Time Factors

Assessment of the Microbiological Quality of a Preservative-Free Multidose System following a Mixed Culture Microbial Immersion Challenge.

Autoren: Perry ID Kroehne L Koutsamanis I et al.

Quelle: PDA journal of pharmaceutical science and technology [PDA J Pharm Sci Technol] 2025 Oct 03; Vol. 79 (5), pp. 483-499. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pda (Parenteral Drug Association) Country of Publication: United States NLM ID: 9439538 Publication Model: Electronic Cited Medium: Internet ISSN: 1948-2124 (Electronic) Linking ISSN: 10797440 NLM ISO Abbreviation: PDA J Pharm Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Biofilms*/growth & development , Ophthalmic Solutions*/standards , Drug Contamination*/prevention & control, Equipment Contamination/prevention & control ; Equipment Design