Suchergebnisse - "ORIGINAL REPORTS"

Phase III Trial of Pirtobrutinib Versus Idelalisib/Rituximab or Bendamustine/Rituximab in Covalent Bruton Tyrosine Kinase Inhibitor–Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-321)

Autoren: Jeff P. Sharman Talha Munir Sebastian Grosicki et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Dateibeschreibung: application/pdf

Zugangs-URL: https://hdl.handle.net/20.500.11768/186321
https://doi.org/10.1200/JCO-25-00166
https://ascopubs.org/doi/10.1200/JCO-25-00166

Pasritamig, a First-in-Class, Bispecific T-Cell Engager Targeting Human Kallikrein 2, in Metastatic Castration-Resistant Prostate Cancer: A Phase I Study: A Phase I Study

Autoren: Mark N. Stein Armelle Vinceneux Debbie Robbrecht et al.

Quelle: J Clin Oncol

Schlagwörter: SDG 3 - Good Health and Well-being, ORIGINAL REPORTS

Zugangs-URL: https://pure.eur.nl/en/publications/9611501c-9296-4900-a4af-1c7e66170aa5
https://doi.org/10.1200/JCO-25-00678

Lenvatinib Plus Pembrolizumab and Chemotherapy Versus Chemotherapy in Advanced Metastatic Gastroesophageal Adenocarcinoma: The Phase III, Randomized LEAP-015 Study

Autoren: Kohei Shitara Sylvie Lorenzen Jin Li et al.

Quelle: J Clin Oncol

Schlagwörter: Male, Adult, Esophageal Neoplasms, Leucovorin, Adenocarcinoma, Antibodies, Monoclonal, Humanized, THERAPY, DOUBLE-BLIND, Stomach Neoplasms, 3211 Oncology and carcinogenesis, Antineoplastic Combined Chemotherapy Protocols, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Capecitabine, Aged, Science & Technology, ADVANCED GASTRIC-CANCER, Phenylurea Compounds, LEAP-015 Investigators, 1103 Clinical Sciences, ORIGINAL REPORTS, Middle Aged, OPEN-LABEL, Progression-Free Survival, Oxaliplatin, Oncology, JUNCTION, Quinolines, Female, Fluorouracil, 1ST-LINE, Life Sciences & Biomedicine

Zugangs-URL: https://lirias.kuleuven.be/handle/20.500.12942/769837
https://doi.org/10.1200/jco-25-00748

Acalabrutinib Plus Bendamustine-Rituximab in Untreated Mantle Cell Lymphoma

Autoren: Michael Wang David Salek David Belada et al.

Quelle: J Clin Oncol

Schlagwörter: 03.02. Klinikai orvostan, ORIGINAL REPORTS

Dateibeschreibung: text

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40311141
https://ascopubs.org/doi/10.1200/JCO-25-00690
https://doi.org/10.1200/JCO-25-00690

Randomized Phase Ib Clinical Trial of DB-020 Intratympanic Injections to Reduce High-Dose Cisplatin Ototoxicity

Autoren: Benedict J. Panizza Stephen John O'Leary Christopher David Hart et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40403227

Randomized Phase III Trial of Ramucirumab Beyond Progression Plus Irinotecan in Patients With Ramucirumab-Refractory Advanced Gastric Cancer: RINDBeRG Trial

Autoren: Daisuke Sakai Shigenori Kadowaki Ryohei Kawabata et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40408613

Randomized Phase II Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab as First-Line Treatment in Advanced Pancreatic Cancer: Survival and Cachexia

Autoren: Inna M. Chen Julia S. Johansen Susann Theile et al.

Quelle: J Clin Oncol
Chen, I M, Johansen, J S, Theile, S, Silverman, L M, Pelz, K R, Madsen, K, Dajani, O, Lim, K Z M, Lorentzen, T, Gaafer, O, Koniaris, L G, Ferreira, A C, Neelon, B, Guttridge, D C, Ostrowski, M C, Zimmers, T A & Nielsen, D 2025, ' Randomized Phase II Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab as First-Line Treatment in Advanced Pancreatic Cancer : Survival and Cachexia ', Journal of Clinical Oncology, vol. 43, no. 18, 01965, pp. 2107-2118 . https://doi.org/10.1200/JCO.23.01965

Schlagwörter: ORIGINAL REPORTS

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40354592
https://curis.ku.dk/ws/files/454749461/chen-et-al-2025-randomized-phase-ii-study-of-nab-paclitaxel-and-gemcitabine-with-or-without-tocilizumab-as-first-line.pdf

Characteristics of Patients and Prognostic Factors Across Treatment Lines in Metastatic Colorectal Cancer: An Analysis From the Aide et Recherche en Cancérologie Digestive Database

Autoren: Jean-Baptiste Bachet Aimery de Gramont Morteza Raeisi et al.

Weitere Verfasser: Jean-Baptiste Bachet Aimery de Gramont Morteza Raeisi et al.

Quelle: J Clin Oncol
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname

Schlagwörter: Male, Databases, Factual, IRINOTECAN, DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, BEVACIZUMAB, MULTICENTER, DOUBLE-BLIND, Còlon - Càncer - Tractament, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales, 3211 Oncology and carcinogenesis, Recte - Càncer - Tractament, Humans, 1112 Oncology and Carcinogenesis, OXALIPLATIN, Oncology & Carcinogenesis, Neoplasm Metastasis, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico, Randomized Controlled Trials as Topic, Aged, Proportional Hazards Models, Science & Technology, Other subheadings::Other subheadings::Other subheadings::/drug therapy, SURVIVAL PREDICTIONS, PLACEBO, Recte - Càncer - Prognosi, 1103 Clinical Sciences, ORIGINAL REPORTS, 1ST-LINE CHEMOTHERAPY, Middle Aged, Prognosis, RANDOMIZED-TRIAL, FLUOROURACIL, Còlon - Càncer - Prognosi, Oncology, Female, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis, Colorectal Neoplasms, Life Sciences & Biomedicine

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40324123
http://hdl.handle.net/11351/13364

Outcomes of Radium-223 and Stereotactic Ablative Radiotherapy Versus Stereotactic Ablative Radiotherapy for Oligometastatic Prostate Cancers: The RAVENS Phase II Randomized Trial

Autoren: Jarey H. Wang Alexander D. Sherry Soha Bazyar et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40334149

Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes

Autoren: Matteo Zampini Elena Riva Luca Lanino et al.

Quelle: J Clin Oncol
Kordasti, S 2025, ' Characterization and Clinical Implications of p53 Dysfunction in Patients with Myelodysplastic Syndromes ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 43, no. 18, JCO-24-02394, pp. 2069-2083 . https://doi.org/10.1200/JCO-24-02394

Schlagwörter: clustering, rna sequencing, myelodisplastic syndromes, multi-omics, ORIGINAL REPORTS

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40315418
https://hdl.handle.net/2434/1185420
https://kclpure.kcl.ac.uk/ws/files/339096572/zampini-et-al-2025-characterization-and-clinical-implications-of-p53-dysfunction-in-patients-with-myelodysplastic.pdf

Second-Line Endocrine Therapy With or Without Palbociclib Rechallenge in Patients With Hormone Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: PALMIRA Trial

Autoren: Antonio Llombart-Cussac Catherine Harper-Wynne Antonia Perelló et al.

Quelle: J Clin Oncol
JOURNAL OF CLINICAL ONCOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza

Schlagwörter: ORIGINAL REPORTS

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40294349
https://fisabio.portalinvestigacion.com/publicaciones/18776
http://zaguan.unizar.es/record/161903

Sequential Infusion of Mesenchymal Stem Cell for Graft-Versus-Host Disease Prevention in Haploidentical Hematopoietic Stem Cell Transplantation: An Open-Label, Multicenter, Randomized Controlled Clinical Trial

Autoren: Han Yao Ruihao Huang Haixia Fu et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40233291

Hematopoietic Stem Cell Transplantation Outcomes for High-Risk AML: A Report From the Children's Oncology Group

Autoren: Benjamin J. Huang Lauren K. Meyer Todd A. Alonzo et al.

Quelle: J Clin Oncol

Schlagwörter: ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40294366

NOTCH1 Mutation and Survival Analysis of Tislelizumab in Advanced or Metastatic Esophageal Squamous Cell Carcinoma: A Biomarker Analysis From the Randomized, Phase III, RATIONALE-302 Trial

Autoren: Zhihao Lu Wenting Du Xi Jiao et al.

Quelle: J Clin Oncol

Schlagwörter: CAMRELIZUMAB, Male, Science & Technology, PLACEBO, Esophageal Neoplasms, 1103 Clinical Sciences, ORIGINAL REPORTS, CHEMOTHERAPY, Middle Aged, Antibodies, Monoclonal, Humanized, THERAPY, Survival Analysis, Mice, Oncology, 3211 Oncology and carcinogenesis, Mutation, Biomarkers, Tumor, Humans, Animals, Female, 1112 Oncology and Carcinogenesis, Esophageal Squamous Cell Carcinoma, Oncology & Carcinogenesis, Receptor, Notch1, Life Sciences & Biomedicine

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40179324

Taletrectinib in ROS1 + Non–Small Cell Lung Cancer: TRUST

Autoren: Maurice Pérol Wei Li Nathan A. Pennell et al.

Weitere Verfasser: Maurice Pérol Wei Li Nathan A. Pennell et al.

Quelle: J Clin Oncol
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname

Schlagwörter: Other subheadings::Other subheadings::Other subheadings::/drug therapy, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Treatment Outcome, ORIGINAL REPORTS, DISEASES::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms::Bronchial Neoplasms::Carcinoma, Bronchogenic::Carcinoma, Non-Small-Cell Lung, CHEMICALS AND DRUGS::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases, Otros calificadores::Otros calificadores::Otros calificadores::/antagonistas & inhibidores, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias torácicas::neoplasias del tracto respiratorio::neoplasias pulmonares::neoplasias de los bronquios::carcinoma broncogénico::carcinoma de pulmón de células no pequeñas, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del tratamiento, Other subheadings::Other subheadings::Other subheadings::/antagonists & inhibitors, COMPUESTOS QUÍMICOS Y DROGAS::enzimas y coenzimas::enzimas::transferasas::fosfotransferasas::fosfotransferasas (grupo alcohol aceptor)::proteína cinasas::proteína-tirosina cinasas, Avaluació de resultats (Assistència sanitària), Pulmons - Càncer - Tractament, Proteïnes quinases - Inhibidors - Ús terapèutic

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40179330
http://hdl.handle.net/11351/13367

Qualitative Study of Health Care Team Perception of the Benefits and Limitations of Remote Symptom Monitoring

Autoren: Emma K. Hendrix Nicole L. Henderson Tanvi V. Padalkar et al.

Quelle: JCO Oncol Pract

Schlagwörter: 03 medical and health sciences, 0302 clinical medicine, ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39661925

Methotrexate, Doxorubicin, and Cisplatin Versus Methotrexate, Doxorubicin, and Cisplatin + Ifosfamide in Poor Responders to Preoperative Chemotherapy for Newly Diagnosed High-Grade Osteosarcoma (JCOG0905): A Multicenter, Open-Label, Randomized Trial

Autoren: Hiroaki Hiraga Ryunosuke Machida Akira Kawai et al.

Quelle: J Clin Oncol

Schlagwörter: Original Reports

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40138604

General Practitioners' Experiences With Implementing Colon or Prostate Cancer Survivorship Care in Primary Care: A Cross-Sectional Survey Nested Within Two Randomized-Controlled Trials: A Cross-Sectional Survey Nested Within Two Randomized-Controlled Trials

Autoren: Julien A.M. Vos Barbara M. Wollersheim Henk C.P.M. van Weert et al.

Quelle: JCO Oncol Pract

Schlagwörter: 03 medical and health sciences, 0302 clinical medicine, ORIGINAL REPORTS

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39621954

High-Dose Methotrexate in Children and Young Adults With ALL and Lymphoblastic Lymphoma: Results of the Randomized Phase III Study UKALL 2011

Autoren: Amy A. Kirkwood Nicholas Goulden John Moppett et al.

Quelle: J Clin Oncol

Schlagwörter: Male, Adult, Antimetabolites, Antineoplastic, Adolescent, Infant, ORIGINAL REPORTS, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dexamethasone, Young Adult, Methotrexate, Child, Preschool, Humans, Female, Child

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40193822

Prognostic Models From Transcriptomic Signatures of the Tumor Microenvironment and Cell Cycle in Stage III Colon Cancer From PETACC-8 and IDEA-France Trials

Autoren: Gallois, Claire Sroussi, Marine André, Thierry et al.

Weitere Verfasser: Gallois, Claire Sroussi, Marine André, Thierry et al.

Quelle: J Clin Oncol
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname

Schlagwörter: Male, DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms::Colonic Neoplasms, Other subheadings::Other subheadings::Other subheadings::/genetics, FENÓMENOS Y PROCESOS::fenómenos genéticos::expresión génica::transcripción genética::fenómenos genéticos::transcriptoma, [SDV]Life Sciences [q-bio], Còlon - Càncer - Aspectes genètics, Biocartis, Transcriptomes, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales::neoplasias del colon, DISEASES::Neoplasms::Neoplastic Processes::Neoplasm Recurrence, Local, Otros calificadores::Otros calificadores::Otros calificadores::/genética, Tumor Microenvironment, Biomarkers, Tumor, Humans, Roche, Neoplasm Staging, Aged, Royalties, Expenses: Roche, Other Intellectual Property: Inventor of mir31-3p license to IntegraGen Travel, Merck, Gene Expression Profiling, Cell Cycle, AstraZeneca, PHENOMENA AND PROCESSES::Genetic Phenomena::Gene Expression::Transcription, Genetic::Genetic Phenomena::Transcriptome, ORIGINAL REPORTS, Bristol Myers Squibb, Middle Aged, Prognosis, Amgen, Boehringer Ingelheim Patents, [SDV] Life Sciences [q-bio], Còlon - Càncer - Prognosi, Accommodations, Còlon - Càncer - Recaiguda, MSD Oncology Consulting or Advisory Role: Merck, ENFERMEDADES::neoplasias::procesos neoplásicos::recurrencia neoplásica local, Colonic Neoplasms, Female, France, Neoplasm Recurrence, Local, Transcriptome, Sanofi

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39889251
http://hdl.handle.net/11351/13348
https://hal.science/hal-04955616v1
https://hal.science/hal-04955616v1/document
https://doi.org/10.1200/jco.23.02262