Suchergebnisse - "ORGANELLES"

Mimicking the process from secretory vesicles to organelles in eukaryotic cell evolution by clustering enzyme-liposomes in artificial cells.

Autoren: Mo S Li X Li Y et al.

Quelle: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Oct 15; Vol. 696, pp. 137863. Date of Electronic Publication: 2025 May 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

MeSH-Schlagworte: Liposomes*/chemistry , Liposomes*/metabolism , Artificial Cells*/metabolism , Artificial Cells*/chemistry , Glucose Oxidase*/chemistry , Glucose Oxidase*/metabolism , Myoglobin*/chemistry , Myoglobin*/metabolism , Secretory Vesicles*/metabolism , Secretory Vesicles*/chemistry , Eukaryotic Cells*/metabolism , Organelles*/metabolism , Organelles*/chemistry, Tannins/chemistry ; Particle Size ; Biological Evolution ; Surface Properties

A molecular census to elucidate the demixing mechanism of membraneless organelles.

Autoren: Ali C Muzzopappa F Erdel F

Quelle: Genome biology [Genome Biol] 2025 Oct 09; Vol. 26 (1), pp. 347. Date of Electronic Publication: 2025 Oct 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

MeSH-Schlagworte: Organelles*/metabolism , Organelles*/genetics, Animals ; Mice ; Heterochromatin/metabolism ; Cell Nucleolus/metabolism ; Mouse Embryonic Stem Cells/metabolism

Quantitative Strategies for Decoding Organelle Ion Dynamics.

Autoren: Anees P; Department of Chemistry, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati, 517619, India.

Quelle: Chembiochem : a European journal of chemical biology [Chembiochem] 2025 Oct 03; Vol. 26 (19), pp. e202500557. Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

MeSH-Schlagworte: Organelles*/metabolism , Organelles*/chemistry , Ions*/metabolism, Humans ; Fluorescent Dyes/chemistry ; Animals ; Ion Transport ; Ion Channels/metabolism

AMPK opens the door to organelle memory and longevity.

Autoren: Sharma A; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA. Electronic address: Arpit.Sharma@tufts.edu.

Quelle: Trends in cell biology [Trends Cell Biol] 2025 Dec; Vol. 35 (12), pp. 990-991. Date of Electronic Publication: 2025 Nov 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 9200566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3088 (Electronic) Linking ISSN: 09628924 NLM ISO Abbreviation: Trends Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: AMP-Activated Protein Kinases*/metabolism , Longevity* , Organelles*/metabolism, Humans ; Animals ; Nuclear Pore Complex Proteins/metabolism

Intracompartmental 3D Printing of Enzymatically Active Organelle Mimics.

Autoren: Sümbelli Y Jäkel AC Verwiel MAM et al.

Quelle: ACS nano [ACS Nano] 2025 Nov 18; Vol. 19 (45), pp. 39327-39336. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

MeSH-Schlagworte: Printing, Three-Dimensional* , Organelles*/chemistry , Organelles*/metabolism , Artificial Cells*/chemistry , Artificial Cells*/metabolism, Polymerization ; beta-Galactosidase/metabolism ; beta-Galactosidase/chemistry ; Methacrylates/chemistry ; Polymers/chemistry

Hybrid of Indolizine and Merocyanine-A New Class of Organelle-Specific Dyes.

Autoren: Badaro JSA Koszarna B Perkowska M et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Nov 17; Vol. 64 (47), pp. e202508044. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Indolizines*/chemistry , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Organelles*/chemistry , Organelles*/metabolism, Humans ; Molecular Structure ; Benzopyrans ; Indoles

Subcellular Organelle-Targeted Drug Delivery of Photodynamic Therapy and Gas-Photodynamic Combination Therapy.

Autoren: Zhang X Wang J Wang S et al.

Quelle: International journal of nanomedicine [Int J Nanomedicine] 2025 Nov 12; Vol. 20, pp. 13661-13687. Date of Electronic Publication: 2025 Nov 12 (Print Publication: 2025).

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

MeSH-Schlagworte: Photochemotherapy*/methods , Photosensitizing Agents*/administration & dosage , Photosensitizing Agents*/chemistry , Photosensitizing Agents*/pharmacokinetics , Photosensitizing Agents*/therapeutic use , Neoplasms*/drug therapy , Drug Delivery Systems*/methods , Organelles*/metabolism , Organelles*/drug effects , Gases*/chemistry, Humans ; Reactive Oxygen Species/metabolism ; Animals ; Tumor Microenvironment/drug effects ; Prodrugs/administration & dosage

Systematic characterization of the composition and dynamics of processing body-associated mRNAs.

Autoren: Sun Z Wen X Li Y et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 10; Vol. 16 (1), pp. 9867. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Organelles*/metabolism , Organelles*/genetics, Humans ; HEK293 Cells ; HCT116 Cells ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; RNA Editing ; Unfolded Protein Response/genetics ; X-Box Binding Protein 1/genetics ; X-Box Binding Protein 1/metabolism ; 3' Untranslated Regions/genetics ; RNA Splicing

Substrate Exclusion Greenlights Physical Autocatalysis of Enzyme Activity in Membraneless Proto-Organelles.

Autoren: Ahmed T Verma A Takayama S

Quelle: Biomacromolecules [Biomacromolecules] 2025 Nov 10; Vol. 26 (11), pp. 7398-7409. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100892849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4602 (Electronic) Linking ISSN: 15257797 NLM ISO Abbreviation: Biomacromolecules Subsets: MEDLINE

MeSH-Schlagworte: Organelles*/enzymology , Organelles*/chemistry, Dextrans/chemistry ; Dextrans/metabolism ; Viscosity ; Hydrolysis ; Biocatalysis ; Catalysis

On the potential roles of TDP-43 in the formation of membraneless organelles and their transformation into toxic aggregates.

Autoren: Sergeeva OS Neklesova MV Reushev VA et al.

Quelle: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Nov 08; Vol. 788, pp. 152808. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH-Schlagworte: DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/chemistry , Organelles*/metabolism , Organelles*/pathology , Protein Aggregation, Pathological*/metabolism , Protein Aggregation, Pathological*/pathology , TDP-43 Proteinopathies*/metabolism , TDP-43 Proteinopathies*/pathology, Humans ; Animals ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Protein Aggregates ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/pathology ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology

Aluminum exposure disturbs epigenetic modification and organelle function during early embryo development.

Autoren: Yu XT Fu ZH Pan WL et al.

Quelle: Chemico-biological interactions [Chem Biol Interact] 2025 Nov 01; Vol. 421, pp. 111736. Date of Electronic Publication: 2025 Sep 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

MeSH-Schlagworte: Embryonic Development*/drug effects , Embryonic Development*/genetics , Epigenesis, Genetic*/drug effects , Aluminum*/toxicity , Organelles*/drug effects , Organelles*/metabolism, Animals ; Mice ; Reactive Oxygen Species/metabolism ; Oxidative Stress/drug effects ; Histones/metabolism ; DNA Damage/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Female ; Embryo, Mammalian/drug effects ; Embryo, Mammalian/metabolism ; Golgi Apparatus/drug effects ; Golgi Apparatus/metabolism ; Lysosomes/drug effects ; Lysosomes/metabolism

Non-equilibrium demixing and dissolution of chiral coacervates via intrinsic catalysis.

Autoren: Gupta S Jha S Mahato C et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 22; Vol. 16 (1), pp. 9336. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Peptides*/chemistry , Peptides*/metabolism , Organelles*/chemistry , Organelles*/metabolism, Catalysis ; Kinetics

Two-Photon Light-Activatable Fluorophores for Organelle Imaging in Living Cells and Tissue-Level Imaging.

Autoren: Ma Z Fu Z Hou B et al.

Quelle: Journal of the American Chemical Society [J Am Chem Soc] 2025 Oct 15; Vol. 147 (41), pp. 37005-37011. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH-Schlagworte: Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Photons* , Organelles*/chemistry , Organelles*/metabolism , Optical Imaging* , Light*, Animals ; Mice ; Humans

Far-red/NIR BODIPY probes in focus: tailored strategies for organelle-specific imaging and biomedical applications.

Autoren: Kalarikkal C Swamy P CA

Quelle: Journal of materials chemistry. B [J Mater Chem B] 2025 Oct 15; Vol. 13 (40), pp. 12831-12868. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-7518 (Electronic) Linking ISSN: 2050750X NLM ISO Abbreviation: J Mater Chem B Subsets: MEDLINE

MeSH-Schlagworte: Boron Compounds*/chemistry , Fluorescent Dyes*/chemistry , Optical Imaging* , Organelles*/chemistry , Organelles*/metabolism, Humans ; Animals

Targeting Subcellular Organelles in Breast Cancer with Enzyme Induced Self-Assembly: Stimulated Response with Eyes-Absence Enzymes (EYA).

Autoren: Carney E Powell R Kumar A et al.

Quelle: Molecular pharmaceutics [Mol Pharm] 2025 Oct 06; Vol. 22 (10), pp. 5914-5927. Date of Electronic Publication: 2025 Sep 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

MeSH-Schlagworte: Breast Neoplasms*/drug therapy , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Protein Tyrosine Phosphatases*/metabolism , Organelles*/metabolism , Organelles*/drug effects, Humans ; Female ; Cell Line, Tumor ; MCF-7 Cells ; Mitochondria/metabolism ; Mitochondria/drug effects ; Peptides/chemistry ; Doxorubicin/pharmacology ; Apoptosis/drug effects

Architectural RNAs: blueprints for functional membraneless organelle assembly.

Autoren: Hirose T Fujiwara N Ninomiya K et al.

Quelle: Trends in genetics : TIG [Trends Genet] 2025 Oct; Vol. 41 (10), pp. 919-933. Date of Electronic Publication: 2025 Jun 12.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 8507085 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0168-9525 (Print) Linking ISSN: 01689525 NLM ISO Abbreviation: Trends Genet Subsets: MEDLINE

MeSH-Schlagworte: Organelles*/genetics , Organelles*/metabolism , RNA*/genetics , RNA, Long Noncoding*/genetics, Humans ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Animals ; Gene Expression Regulation

Solving Mazes of Organelle-Targeted Therapies with DNA Nanomachines.

Autoren: Farooq MU Lawrie CH Deng NN

Quelle: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2025 Oct; Vol. 37 (39), pp. e2508047. Date of Electronic Publication: 2025 Jul 11.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9885358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4095 (Electronic) Linking ISSN: 09359648 NLM ISO Abbreviation: Adv Mater Subsets: MEDLINE

MeSH-Schlagworte: DNA*/chemistry , Organelles*/metabolism , Organelles*/drug effects , Nanostructures*/chemistry, Humans ; Animals ; Neoplasms/drug therapy ; Drug Carriers/chemistry

Review: Adaptation of plants to phosphorus scarcity: From nutritional crosstalk to organellar function.

Autoren: Bucio JSL González JR Bucio JL

Quelle: Plant science : an international journal of experimental plant biology [Plant Sci] 2025 Oct; Vol. 359, pp. 112685. Date of Electronic Publication: 2025 Jul 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Ireland Country of Publication: Ireland NLM ID: 9882015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2259 (Electronic) Linking ISSN: 01689452 NLM ISO Abbreviation: Plant Sci Subsets: MEDLINE

MeSH-Schlagworte: Phosphorus*/deficiency , Phosphorus*/metabolism , Adaptation, Physiological* , Plant Physiological Phenomena* , Organelles*/physiology , Organelles*/metabolism, Plant Roots/metabolism ; Plant Roots/physiology ; Plant Roots/growth & development

From loss of Ca ²⁺ -influx to altered organelle temperature and energy failure: A neonatal-lethal TRPV4 mutant (L618P).

Autoren: Mishra S Dubey NK Das NK et al.

Quelle: Life sciences [Life Sci] 2025 Dec 15; Vol. 383, pp. 124039. Date of Electronic Publication: 2025 Oct 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

MeSH-Schlagworte: TRPV Cation Channels*/genetics , TRPV Cation Channels*/metabolism , Calcium*/metabolism , Organelles*/metabolism , Energy Metabolism*, Animals ; Mitochondria/metabolism ; Humans ; Mutation ; Temperature ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/cytology ; Cell Line ; Endoplasmic Reticulum/metabolism ; Rats

FRET-based biosensor moxCRONOS enables quantitative monitoring of macromolecular crowding in organelles and protein aggregates.

Autoren: Nakajima Y Suzuki H Miyagi T et al.

Quelle: Journal of biochemistry [J Biochem] 2025 Dec 02; Vol. 178 (6), pp. 403-414.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN: 1756-2651 (Electronic) Linking ISSN: 0021924X NLM ISO Abbreviation: J Biochem Subsets: MEDLINE

MeSH-Schlagworte: Fluorescence Resonance Energy Transfer*/methods , Biosensing Techniques*/methods , Protein Aggregates* , Organelles*/metabolism, Humans