Suchergebnisse - "Non-Receptor Type 11/genetics"

Rasopathy-Associated Mutation Ptpn11D61Y has Age-Dependent Effect on Synaptic Vesicle Recycling

Autoren: Guhathakurta, Debarpan Selzam, Franziska Petrušková, Aneta et al.

Quelle: Cell Mol Neurobiol
Cellular and Molecular Neurobiology

Schlagwörter: Neurons, 0301 basic medicine, Mice, Aging, 0303 health sciences, 03 medical and health sciences, Mutation, Animals, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Synaptic Vesicles, Mutation/genetics [MeSH], Synaptic Vesicles/metabolism [MeSH], Mice [MeSH], Aging/genetics [MeSH], Neurons/metabolism [MeSH], Aging/metabolism [MeSH], Protein Tyrosine Phosphatase, Non-Receptor Type 11/metabolism [MeSH], Cells, Cultured [MeSH], Original Research, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics [MeSH], Animals [MeSH], Cells, Cultured

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39570442
https://repository.publisso.de/resource/frl:6489145

Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients: a multinational cohort of 519 patients

Autoren: Halik, Adriane Tilgner, Marlon Silva, Patricia et al.

Quelle: J Hematol Oncol
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)

Schlagwörter: Male, Adult, 0301 basic medicine, Cancer Research, Adolescent, DNA Copy Number Variations, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Monosomy 7, Cohort Studies, Young Adult, 03 medical and health sciences, SDG 3 - Good Health and Well-being, AML, del(7q), Exome Sequencing, Humans, Diseases of the blood and blood-forming organs, TP53, RC254-282, Aged, Chromosome Aberrations, Aged, 80 and over, 0303 health sciences, Aged, 80 and over [MeSH], Aged [MeSH], Leukemia, Myeloid, Acute/mortality [MeSH], Cohort Studies [MeSH], Male [MeSH], Leukemia, Myeloid, Acute/genetics [MeSH], Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics [MeSH], Chromosome Aberrations [MeSH], Adolescent [MeSH], Female [MeSH], Mutation [MeSH], Adult [MeSH], Humans [MeSH], Chromosomes, Human, Pair 7/genetics [MeSH], Genomics/methods [MeSH], Middle Aged [MeSH], Exome Sequencing [MeSH], Tumor Suppressor Protein p53/genetics [MeSH], DNA Copy Number Variations [MeSH], Research, Prognosis [MeSH], Young Adult [MeSH], Leukemia, Myeloid, Acute/drug therapy [MeSH], Complex karyotype, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, KMT2C, Genomics, Middle Aged, Prognosis, 3. Good health, Leukemia, Myeloid, Acute, Mutation, Female, RC633-647.5, Tumor Suppressor Protein p53, Chromosomes, Human, Pair 7

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39160538
https://doaj.org/article/c4bde76aa3284c6f887bca011315517d
https://pure.eur.nl/en/publications/d5d46142-9d53-4b2a-ac4e-22b8a30fb9a7
https://doi.org/10.1186/s13045-024-01590-1
https://edoc.mdc-berlin.de/id/eprint/24622/2/24622suppl.zip
https://ora.ox.ac.uk/objects/uuid:c42613d1-4872-4aa7-880e-e2bbcc3481ae
https://doi.org/10.1186/s13045-024-01590-1
https://repository.publisso.de/resource/frl:6491728

Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

Autoren: Franciosa, Giulia Olsen, Jesper V

Quelle: Oncotarget
Franciosa, G & Olsen, J V 2023, ' Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors ', OncoTarget, vol. 14, pp. 281-283 . https://doi.org/10.18632/oncotarget.28392

Schlagwörter: Enzyme Inhibitors/pharmacology, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Tumor, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Cell Line, Non-Receptor Type 11/genetics, Editorial, Protein Kinase Inhibitors/pharmacology, Cell Line, Tumor, Humans, Tyrosine, Protein Tyrosine Phosphatase, Phosphorylation, Enzyme Inhibitors, Protein Kinase Inhibitors

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36999992
https://curis.ku.dk/ws/files/347114335/oncotarget_v14_28392.pdf

Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects

Autoren: Solman, Maja Blokzijl-Franke, Sasja Piques, Florian et al.

Quelle: Solman , M , Blokzijl-Franke , S , Piques , F , Yan , C , Yang , Q , Strullu , M , Kamel , S M , Ak , P , Bakkers , J , Langenau , D M , Cavé , H & den Hertog , J 2022 , ' Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects ' , eLife , vol. 11 . https://doi.org/10.7554/eLife.73040

Schlagwörter: Animals, Hematopoietic Stem Cells/metabolism, Humans, Leukemia, Myelomonocytic, Juvenile/genetics, Mutation, Noonan Syndrome/genetics, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Zebrafish

Verfügbarkeit: https://pure.knaw.nl/portal/en/publications/49ac1364-f68c-4d6e-8a97-fd371a0c2425
https://doi.org/10.7554/eLife.73040
https://hdl.handle.net/20.500.11755/49ac1364-f68c-4d6e-8a97-fd371a0c2425

Modelling signalling networks from perturbation data

Autoren: Anja Sieber Bertram Klinger Torsten Gross et al.

Quelle: Bioinformatics. 34:4079-4086

Schlagwörter: 0301 basic medicine, Tumor, 0206 medical engineering, Computational Biology, Protein Tyrosine Phosphatase, Non-Receptor Type 11, 02 engineering and technology, Cell Line, 3. Good health, Non-Receptor Type 11/genetics, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Colonic Neoplasms, Humans, Protein Tyrosine Phosphatase, Software, Signal Transduction

Zugangs-URL: https://academic.oup.com/bioinformatics/article-pdf/34/23/4079/26676689/bty473.pdf
https://pubmed.ncbi.nlm.nih.gov/29931053
https://hdl.handle.net/1871.1/f85e4806-32f3-4bed-8b1c-261206a6b348
https://research.vu.nl/en/publications/f85e4806-32f3-4bed-8b1c-261206a6b348
https://doi.org/10.1093/bioinformatics/bty473
https://academic.oup.com/bioinformatics/article-pdf/34/23/4079/26676689/bty473.pdf
https://www.ncbi.nlm.nih.gov/pubmed/29931053
https://research.vu.nl/en/publications/modelling-signalling-networks-from-perturbation-data
https://academic.oup.com/bioinformatics/article/34/23/4079/5040310
https://dblp.uni-trier.de/db/journals/bioinformatics/bioinformatics34.html#DorelKGSPBWB18
https://www.narcis.nl/publication/RecordID/oai%3Aresearch.vu.nl%3Apublications%2Ff85e4806-32f3-4bed-8b1c-261206a6b348
https://www.biorxiv.org/content/10.1101/243600v1
https://www.biorxiv.org/content/biorxiv/early/2018/01/05/243600.full.pdf

Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects

Autoren: Maja Solman Sasja Blokzijl-Franke Florian Piques et al.

Weitere Verfasser: Maja Solman Sasja Blokzijl-Franke Florian Piques et al.

Quelle: eLife
eLife, Vol 11 (2022)

Schlagwörter: 0301 basic medicine, QH301-705.5, Science, Protein Tyrosine Phosphatase, Non-Receptor Type 11, 03 medical and health sciences, Noonan Syndrome/genetics, Hematopoietic Stem Cells/metabolism, Noonan syndrome, Animals, Humans, Biology (General), Juvenile/genetics, RASopathies, Zebrafish, Cancer Biology, 0303 health sciences, Leukemia, Noonan Syndrome, leukemia, Myelomonocytic, Hematopoietic Stem Cells, hematopoiesis, 3. Good health, Non-Receptor Type 11/genetics, Leukemia, Myelomonocytic, Juvenile, Mutation, SHP2, Medicine, Protein Tyrosine Phosphatase

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.biorxiv.org/content/biorxiv/early/2020/09/10/2020.09.10.289090.full.pdf
https://pubmed.ncbi.nlm.nih.gov/35535491
https://doaj.org/article/3707551dbdd84387be86bb4473d1395a
https://biorxiv.org/content/10.1101/2020.09.10.289090v1.full.pdf
https://www.biorxiv.org/content/10.1101/2020.09.10.289090v1
https://www.biorxiv.org/content/10.1101/2020.09.10.289090v1.article-info
https://www.biorxiv.org/content/biorxiv/early/2021/09/01/2020.09.10.289090.full.pdf
https://www.biorxiv.org/content/10.1101/2020.09.10.289090v2
https://dspace.library.uu.nl/handle/1874/447489

Helicobacter pylori CagA Phosphorylation Status Determines the gp130-activated SHP2/ERK and JAK/STAT Signal Transduction Pathways in Gastric Epithelial Cells

Autoren: Michael H. Pillinger Seok-Yong Kim Yeun Jung Choi et al.

Weitere Verfasser: Michael H. Pillinger Seok-Yong Kim Yeun Jung Choi et al.

Quelle: Journal of Biological Chemistry. 285:16042-16050

Schlagwörter: 0301 basic medicine, Bacterial Proteins/metabolism, STAT3 Transcription Factor/metabolism, Bacterial/genetics, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Mice, Cytokine Receptor gp130, Phosphorylation, Cells, Cultured, Mice, Knockout, 0303 health sciences, Cultured, Mitogen-Activated Protein Kinase 3, Stomach, Helicobacter pylori/genetics, Non-Receptor Type 11/genetics, Janus Kinases/metabolism, STAT3 Transcription Factor, Mitogen-Activated Protein Kinase 3/metabolism, MAP Kinase Signaling System, Cells, Knockout, Janus Kinases/genetics, STAT3 Transcription Factor/genetics, Bacterial/metabolism, Epithelial Cells/metabolism, 03 medical and health sciences, Bacterial Proteins, Non-Receptor Type 11/metabolism, Animals, Humans, Antigens, Janus Kinases, Cytokine Receptor gp130/genetics, Epithelial Cells/microbiology, Stomach/metabolism, Antigens, Bacterial, Helicobacter pylori, Bacterial Proteins/genetics, Mitogen-Activated Protein Kinase 3/genetics, Cytokine Receptor gp130/metabolism, Epithelial Cells, Helicobacter pylori/metabolism, Gastric Mucosa, Phosphorylation/genetics, Protein Tyrosine Phosphatase, Stomach/microbiology

Dateibeschreibung: 16042~16050

Zugangs-URL: http://www.jbc.org/content/285/21/16042.full.pdf
https://pubmed.ncbi.nlm.nih.gov/20348091
https://www.jbc.org/article/S0021-9258(20)49417-7/fulltext
https://pubmed.ncbi.nlm.nih.gov/20348091/
https://mdanderson.elsevierpure.com/en/publications/helicobacter-pylori-caga-phosphorylation-status-determines-the-gp
https://www.jbc.org/content/285/21/16042.long
https://europepmc.org/abstract/MED/20348091
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871473/

Germline PTPN11 missense mutation in a case of Noonan syndrome associated with mediastinal and retroperitoneal neuroblastic tumors

Autoren: Mutesa, Léon Pierquin, Geneviève Janin, Nicolas et al.

Quelle: Cancer Genetics and Cytogenetics. 182:40-42

Schlagwörter: 0301 basic medicine, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Retroperitoneal Neoplasms/complications/genetics, Pédiatrie, Mediastinal Neoplasms/complications/genetics, Noonan Syndrome, Mutation, Missense, Infant, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Neuroblastoma/complications/genetics, Pediatrics, Sciences de la santé humaine, Mediastinal Neoplasms, Noonan Syndrome/complications/genetics, 3. Good health, Neuroblastoma, 03 medical and health sciences, 0302 clinical medicine, Humans, Abnormalities, Multiple, Female, Retroperitoneal Neoplasms, Human health sciences, Germ-Line Mutation

Zugangs-URL: https://orbi.uliege.be/bitstream/2268/5141/1/Art%20Noonan%20syndrome%20associated%20with%20neuroblastoma.pdf
https://pubmed.ncbi.nlm.nih.gov/18328949
https://orbi.uliege.be/handle/2268/5141
http://orbi.ulg.ac.be/bitstream/2268/5141/1/Art%20Noonan%20syndrome%20associated%20with%20neuroblastoma.pdf
https://www.sciencedirect.com/science/article/pii/S0165460807008114
https://orbi.ulg.ac.be/bitstream/2268/5141/1/Art%20Noonan%20syndrome%20associated%20with%20neuroblastoma.pdf
http://core.ac.uk/display/13338384
https://www.ncbi.nlm.nih.gov/pubmed/18328949
https://hdl.handle.net/2268/5141
https://doi.org/10.1016/j.cancergencyto.2007.12.005

Modelling signalling networks from perturbation data

Autoren: Dorel, Mathurin Klinger, Bertram Gross, Torsten et al.

Quelle: Vrije Universiteit Amsterdam Repository

Index Begriffe: Cell Line, Tumor, Colonic Neoplasms, Computational Biology, Humans, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Signal Transduction, Software, SDG 3 - Good Health and Well-being, Article

URL: https://research.vu.nl/en/publications/f85e4806-32f3-4bed-8b1c-261206a6b348
https://research.vu.nl/ws/files/246718143/Modelling_signalling_networks_from_perturbation_data.pdf
https://research.vu.nl/ws/files/246718143/Modelling_signalling_networks_from_perturbation_data.pdf