Search Results - "Neurosciences & Neurology"

Exploring walking-dependent co-activation of quadriceps and hamstrings muscles using an isolated leg-swinging paradigm

Authors: Van Can, Ellis A.M. Houdijk, Han Buurke, Tom J.W.

Source: Gait & Posture. 122:204-210

Subject Terms: Male, Adult, SURFACE, MOTION, 1106 Human Movement and Sports Sciences, Hamstring Muscles, Walking, Quadriceps Muscle, Young Adult, Motor control, Humans, Gait, SCALE, 4003 Biomedical engineering, 4207 Sports science and exercise, Neuromechanics, Science & Technology, Electromyography, Neurosciences, Co-contraction, 1103 Clinical Sciences, Healthy Volunteers, Biomechanical Phenomena, Orthopedics, INTERRATER RELIABILITY, PATTERNS, Female, 4201 Allied health and rehabilitation science, Neurosciences & Neurology, Life Sciences & Biomedicine, GAIT, Sport Sciences, 0913 Mechanical Engineering

Access URL: https://hdl.handle.net/11370/f1cec2ca-d8ec-42e9-921c-5430c5ec99c0
https://research.rug.nl/en/publications/f1cec2ca-d8ec-42e9-921c-5430c5ec99c0
https://doi.org/10.1016/j.gaitpost.2025.07.317
https://lirias.kuleuven.be/handle/20.500.12942/770250
https://doi.org/10.1016/j.gaitpost.2025.07.317

Children with and without relapsed clubfoot show task-specific deviations in lower limb kinematics during several dynamic activities compared to typically developing children

Authors: Grin, L. van der Steen, M.C. van Dijk, L.S. et al.

Source: Gait & Posture. 122:112-119

Subject Terms: Male, Kinematics, 1106 Human Movement and Sports Sciences, GAIT ANALYSIS, Walking, OXFORD FOOT MODEL, IDIOPATHIC CLUBFOOT, Running, Clubfoot assessment protocol, WORLDWIDE, Recurrence, Humans, Relapse, Range of Motion, Articular, Child, Gait, 4003 Biomedical engineering, 4207 Sports science and exercise, Science & Technology, Neurosciences, 1103 Clinical Sciences, Biomechanical Phenomena, Clubfoot, Orthopedics, Lower Extremity, Case-Control Studies, Child, Preschool, Movement analysis, PONSETI METHOD, FOREFOOT SUPINATION, Female, 4201 Allied health and rehabilitation science, Neurosciences & Neurology, Multi segment foot model, Life Sciences & Biomedicine, Sport Sciences, Ponseti, 0913 Mechanical Engineering

Access URL: https://lirias.kuleuven.be/handle/20.500.12942/770673
https://doi.org/10.1016/j.gaitpost.2025.07.309

The Oxford Cognitive Screen in culturally diverse populations: A comparative study of Suriname and Belgium

Authors: Gangaram-Panday, Shonima G. Huygelier, Hanne Demeyere, Nele et al.

Source: Journal of the International Neuropsychological Society. :1-12

Subject Terms: NORMATIVE DATA, Clinical Neurology, Social Sciences, MINI-MENTAL-STATE, cultural adaptation, OCS VALIDATION, NEUROPSYCHOLOGY, Neurocognitive disorders, cognitive testing, Psychology, ADAPTATION, METAANALYSIS, 11 Medical and Health Sciences, Psychiatry, Science & Technology, 42 Health sciences, cross-cultural comparison, DEMENTIA, Neurosciences, Experimental Psychology, 32 Biomedical and clinical sciences, IMPAIRMENT, stroke, PREVALENCE, 17 Psychology and Cognitive Sciences, 52 Psychology, Neurosciences & Neurology, cultural diversity, Life Sciences & Biomedicine, ACUTE STROKE

Clinically Meaningful Reduction in Drop Seizures in Patients with Lennox–Gastaut Syndrome Treated with Cannabidiol: Post Hoc Analysis of Phase 3 Clinical Trials

Authors: Nicola Specchio Stéphane Auvin Teresa Greco et al.

Source: CNS Drugs. 39:1025-1036

Subject Terms: Adult, Male, Adolescent, Clinical Neurology, 3214 Pharmacology and pharmaceutical sciences, DOUBLE-BLIND, Young Adult, Double-Blind Method, QUALITY-OF-LIFE, Seizures, MANAGEMENT, Humans, Cannabidiol, Pharmacology & Pharmacy, Child, EPILEPSY, Psychiatry, Science & Technology, Lennox Gastaut Syndrome, 3202 Clinical sciences, 1103 Clinical Sciences, Middle Aged, Treatment Outcome, Child, Preschool, 3209 Neurosciences, Female, Anticonvulsants, Neurosciences & Neurology, 1115 Pharmacology and Pharmaceutical Sciences, 1109 Neurosciences, Life Sciences & Biomedicine

Access URL: https://lirias.kuleuven.be/handle/20.500.12942/772670
https://doi.org/10.1007/s40263-025-01201-8

The concept, intention, and evaluation of the term treatment-refractory meningioma

Authors: Lasse Rehné Jensen Andrea Daniela Maier Tareq A. Juratli et al.

Source: Journal of Neuro-Oncology. 175:599-610

Subject Terms: Clinical Neurology, PROGRESSIVE MENINGIOMA, Recommendations, CLASSIFICATION, RECURRENT MENINGIOMA, OCTREOTIDE, 3211 Oncology and carcinogenesis, BRAIN INVASION, Meningeal Neoplasms, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Science & Technology, Treatment-refractory, Individual participant data, Retrospective cohort, Oncology, Drug Resistance, Neoplasm, 3209 Neurosciences, Disease Progression, Neurosciences & Neurology, RECEPTOR RADIONUCLIDE THERAPY, Meningioma, 1109 Neurosciences, Life Sciences & Biomedicine, Progressive meningioma, PHASE-II TRIAL

Access URL: https://lirias.kuleuven.be/handle/20.500.12942/773067
https://doi.org/10.1007/s11060-025-05154-2

Neuropsychological assessment practices in PRECISION-ALS: challenges and opportunities for harmonization

Authors: Emmet Costello Joke De Vocht Emily Beswick et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. :1-10

Subject Terms: Science & Technology, DISORDERS, Amyotrophic Lateral Sclerosis, Clinical Neurology, 1103 Clinical Sciences, ECAS, IMPAIRMENT, BEHAVIORAL-CHANGES, DEPRESSION, AMYOTROPHIC-LATERAL-SCLEROSIS, VALIDATION, DYSFUNCTION, behaviour, Cognition, 3209 Neurosciences, TOOL, COGNITION, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine

Accuracy of blood-based neurofilament light to different genetic frontotemporal dementia from primary psychiatric disorders

Authors: Liu, Ella Jones, Sherri Lee Seelaar, Harro et al.

Contributors: Liu, Ella Jones, Sherri Lee Seelaar, Harro et al.

Source: Journal of Alzheimer's disease 106(4), 1337-1354 (2025). doi:10.1177/13872877251352103

Subject Terms: BIOMARKER, blood [Frontotemporal Dementia], Male, diagnosis, 1702 Cognitive Sciences, blood [Neurofilament Proteins], genetics [Mental Disorders], frontotemporal dementia, genetics [Progranulins], diagnosis [Frontotemporal Dementia], Progranulins, Neurofilament Proteins, BEHAVIORAL VARIANT, BRAIN ATROPHY, genetics [Frontotemporal Dementia], Aged, 80 and over, blood [Biomarkers], blood [Mental Disorders], Mental Disorders, DEATH, DEGENERATION, Middle Aged, Alzheimer's disease, neurofilament proteins, Frontotemporal Dementia, Female, Life Sciences & Biomedicine, Adult, biomarkers, genetics [Mutation], tau Proteins, MAPT protein, human, diagnosis [Mental Disorders], Sensitivity and Specificity, Diagnosis, Differential, SDG 3 - Good Health and Well-being, Humans, ddc:610, PROGRANULIN, neurofilament protein L, genetics [C9orf72 Protein], Aged, Science & Technology, Neurology & Neurosurgery, C9orf72 Protein, Neurosciences, 3202 Clinical sciences, 1103 Clinical Sciences, genetics [tau Proteins], 5202 Biological psychology, Mutation, 3209 Neurosciences, GRN protein, human, CHAIN, Neurosciences & Neurology, Genetic Frontotemporal Dementia Initiative (GENFI) and Banque Signature (BbS), C9orf72 protein, human, 1109 Neurosciences, Biomarkers

File Description: application/pdf

Access URL: https://pub.dzne.de/record/280966

Increased coactivation during clinical tests of spasticity is associated with increased coactivation during reactive standing balance control in cerebral palsy

Authors: Willaert, Jente Ting, Lena H. Van Campenhout, Anja et al.

Source: Journal of Neurophysiology. 134:118-127

Subject Terms: Male, Adolescent, Physiology, CHILDREN, joint hyper-resistance, MUSCLES, Humans, COCONTRACTION, Child, Muscle, Skeletal, Postural Balance, 11 Medical and Health Sciences, muscle coactivation, Science & Technology, Neurology & Neurosurgery, 42 Health sciences, Electromyography, Cerebral Palsy, neural response to stretch, Neurosciences, relation between joint hyper-resistance and functional movements, 32 Biomedical and clinical sciences, FACILITATION, 17 Psychology and Cognitive Sciences, RECIPROCAL INHIBITION, instrumented spasticity assessments, Muscle Spasticity, 52 Psychology, Standing Position, STRETCH REFLEXES, Female, Neurosciences & Neurology, Ankle, Life Sciences & Biomedicine, GAIT, Ankle Joint

Access URL: https://lirias.kuleuven.be/handle/20.500.12942/769027
https://doi.org/10.1152/jn.00568.2024

Construct validity of markerless three-dimensional gait biomechanics in healthy older adults

Authors: Carvalho, Andreia Vanrenterghem, Jos Cabral, Silvia et al.

Contributors: Carvalho, Andreia Vanrenterghem, Jos Cabral, Silvia et al.

Source: Gait & Posture. 120:217-225

Subject Terms: Male, FALLERS, Kinematics, Knee Joint, 1106 Human Movement and Sports Sciences, Walking, Humans, KINEMATICS, Range of Motion, Articular, Physiotherapy, Gait, METAANALYSIS, Aged, 4003 Biomedical engineering, 4207 Sports science and exercise, Science & Technology, Methods comparison, Rehabilitation, Neurosciences, Reproducibility of Results, 1103 Clinical Sciences, Middle Aged, Healthy Volunteers, Correlation, Biomechanical Phenomena, Kinetics, Orthopedics, Cross-Sectional Studies, AGREEMENT, RELIABILITY, YOUNG, Marker-based, Female, Hip Joint, 4201 Allied health and rehabilitation science, Neurosciences & Neurology, Gait Analysis, Life Sciences & Biomedicine, Sport Sciences, Ankle Joint, 0913 Mechanical Engineering

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40286643
https://lirias.kuleuven.be/handle/20.500.12942/764425
https://doi.org/10.1016/j.gaitpost.2025.04.022
https://hdl.handle.net/10400.21/21911

Motor dysfunction in late life depression: A mood or movement disorder?

Authors: Van Cauwenberge, Margot G.A. Vande Casteele, Thomas Laroy, Maarten et al.

Source: Journal of Affective Disorders. 381:680-691

Subject Terms: Male, SYMPTOMS, Clinical Neurology, Neuropsychological Tests, THERAPY, VALIDATION, Digital technology, Humans, PSYCHOMOTOR RETARDATION, SCALE, 11 Medical and Health Sciences, Aged, Psychiatry, Aged, 80 and over, Psychiatric Status Rating Scales, Depressive Disorder, Science & Technology, Movement Disorders, 42 Health sciences, Depressive disorder, Depression, Psychomotor, SLOWNESS, 32 Biomedical and clinical sciences, Middle Aged, STATE, 17 Psychology and Cognitive Sciences, 52 Psychology, PATTERNS, Falls, Female, Accidental Falls, Neurosciences & Neurology, Cues, Life Sciences & Biomedicine, PARKINSONIAN SIGNS, MATTER

Access URL: https://pubmed.ncbi.nlm.nih.gov/40203967
https://lirias.kuleuven.be/handle/20.500.12942/763868
https://doi.org/10.1016/j.jad.2025.04.053

IDO2-AhR axis as central regulator of the kynurenine pathway in glioblastoma

Authors: Jacquerie, Arnaud Macamo, Amanda Hoeben, Ann et al.

Source: J Neurooncol

Subject Terms: EXPRESSION, Male, Adult, TDO2, Clinical Neurology, IDO, 3211 Oncology and carcinogenesis, Basic Helix-Loop-Helix Transcription Factors, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Kynurenine, Aged, Science & Technology, Brain Neoplasms, Research, AhR, Middle Aged, Tryptophan Oxygenase, Oncology, Receptors, Aryl Hydrocarbon, 3209 Neurosciences, T-CELLS, Female, Neurosciences & Neurology, Glioblastoma, 1109 Neurosciences, Life Sciences & Biomedicine, Signal Transduction

Access URL: https://cris.maastrichtuniversity.nl/en/publications/976c9752-c427-4594-9ca0-5ffbe8944302
https://doi.org/10.1007/s11060-025-05106-w
https://lirias.kuleuven.be/handle/20.500.12942/766626
https://doi.org/10.1007/s11060-025-05106-w

Age-related differences in task-related modulation of cerebellar brain inhibition

Authors: Van Malderen, Shanti Hehl, Melina Nuyts, Marten et al.

Contributors: Van Malderen, Shanti Hehl, Melina Nuyts, Marten et al.

Source: Neurobiology of Aging, Vol. 150, no.1, p. 53-68 (2025)

Subject Terms: Male, Adult, TRANSCRANIAL MAGNETIC STIMULATION, Aging, Geriatrics & Gerontology, Motor learning, Dual-site TMS, MECHANISMS, Young Adult, Transcranial magnetic stimulation (TMS), Cerebellum, Humans, Learning, Cerebellar brain inhibition (CBI), MOTOR CORTEX, Aged, SENSORIMOTOR, Science & Technology, Neurology & Neurosurgery, Neurosciences, COIL, 1103 Clinical Sciences, Neural Inhibition, MONTREAL COGNITIVE ASSESSMENT, FUNCTIONAL CONNECTIVITY, Middle Aged, Transcranial Magnetic Stimulation, BIMANUAL COORDINATION, 5202 Biological psychology, EXCITABILITY, VOLUME, 3209 Neurosciences, Female, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine, Psychomotor Performance

Access URL: https://pubmed.ncbi.nlm.nih.gov/40068243
https://hdl.handle.net/2078.1/303178

Repeated exposure to cutaneous high-frequency electrical stimulation prolongs the time course of secondary hyperalgesia

Authors: Louisien Lebrun Alexandre Stouffs Emmanuel Hermans et al.

Contributors: Louisien Lebrun Alexandre Stouffs Emmanuel Hermans et al.

Source: Journal of Neurophysiology, (2025)
Journal of neurophysiology, Vol. 133, no.6, p. 1933-1946 (2025)

Subject Terms: Male, Adult, Pain Threshold, Time Factors, Physiology, Young Adult, secondary hyperalgesia, CENTRAL SENSITIZATION, Humans, high-frequency stimulation, PLASTICITY, long term potentiation, HYPERSENSITIVITY, 11 Medical and Health Sciences, DECLINE, Science & Technology, Neurology & Neurosurgery, 42 Health sciences, Neurosciences, PAIN, central sensitization, 32 Biomedical and clinical sciences, DEPRESSION, NOCICEPTION, Electric Stimulation, 17 Psychology and Cognitive Sciences, Hyperalgesia, 52 Psychology, Female, Neurosciences & Neurology, LONG-TERM POTENTIATION, LTP, INJECTION, Life Sciences & Biomedicine

Access URL: https://pubmed.ncbi.nlm.nih.gov/40354167
https://hdl.handle.net/2078.1/301353
https://hdl.handle.net/2078.1/303519

Preoperative assessment of tumor eloquence and resectability: an international survey: an international survey

Authors: Emma Rammeloo Jacob S. Young Joost W. Schouten et al.

Source: Journal of Neuro-Oncology. 175:47-59

Subject Terms: RESECTION, Clinical Neurology, Neurosurgery, GLIOBLASTOMA, Functional areas, Neurosurgical Procedures, Surveys and Questionnaires, 3211 Oncology and carcinogenesis, Preoperative Care, Neuro-oncology, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Survey, Science & Technology, Brain Neoplasms, Eloquence, Glioma, GLIOMAS, Neurosurgeons, Oncology, 3209 Neurosciences, SURVIVAL, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine, SYSTEM, Decision-making

Access URL: https://pubmed.ncbi.nlm.nih.gov/40397319
https://pure.eur.nl/en/publications/4e9c8443-02a1-44f4-8080-f6d74d9928db
https://doi.org/10.1007/s11060-025-05067-0

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Authors: Vanderlinden, Greet Carron, Charles Van Weehaeghe, Donatienne et al.

Source: Ann Clin Transl Neurol
Annals of Clinical and Translational Neurology, Vol 12, Iss 7, Pp 1350-1359 (2025)

Subject Terms: Male, amyotrophic lateral sclerosis, positron emission tomography, ACETYLATION, Clinical Neurology, INHIBITION, Neurosciences. Biological psychiatry. Neuropsychiatry, Histone Deacetylase 6, histone deacetylase 6, Humans, Cognitive Dysfunction, RC346-429, AGGRESOME, Aged, Science & Technology, Amyotrophic Lateral Sclerosis, Neurosciences, NEURODEGENERATION, Brain, 1103 Clinical Sciences, MOUSE MODEL, HDAC6, AGGREGATION, Middle Aged, 5203 Clinical and health psychology, AUTOPHAGIC FLUX, Positron-Emission Tomography, Frontotemporal Dementia, 3209 Neurosciences, Female, Neurosciences & Neurology, Neurology. Diseases of the nervous system, 1109 Neurosciences, Life Sciences & Biomedicine, RC321-571, Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/40333935
https://doaj.org/article/b4908836213047eba38871a92941d931

Mapping the natural history of amyotrophic lateral sclerosis: time-to-event analysis of clinical milestones in the pan-European, population-based PRECISION-ALS cohort

Authors: Caravaca Puchades, Alejandro McDonough, Harry E. Al-Chalabi, Ammar et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 26:8-19

Subject Terms: Male, Adult, disease trajectory, IMPACT, Clinical Neurology, survival analysis, Cohort Studies, disease progression, Superoxide Dismutase-1, Time-to-event, Humans, Age of Onset, clinical milestones, Aged, Gastrostomy, Science & Technology, Noninvasive Ventilation, C9orf72 Protein, Amyotrophic Lateral Sclerosis, 1103 Clinical Sciences, Middle Aged, Prognosis, Europe, TRIALS, 3209 Neurosciences, SURVIVAL, Disease Progression, Female, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine

Access URL: https://pubmed.ncbi.nlm.nih.gov/40326915

Clinical trajectories of genetic variants in ALS: a European observational study within PRECISION-ALS

Authors: Robert McFarlane Sarah Opie-Martin Alejandro Caravaca Puchades et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 26:41-49

Subject Terms: Male, Adult, Clinical Neurology, Superoxide Dismutase-1, Genetics, Humans, Registries, Genetic Testing, Age of Onset, MUTATION, Aged, Science & Technology, us, tardbp, C9orf72 Protein, HERITABILITY, Amyotrophic Lateral Sclerosis, Genetic Variation, 1103 Clinical Sciences, Middle Aged, c9orf72, Europe, DNA-Binding Proteins, sod1, 3209 Neurosciences, RNA-Binding Protein FUS, Female, Neurosciences & Neurology, 1109 Neurosciences, Life Sciences & Biomedicine

Access URL: https://pubmed.ncbi.nlm.nih.gov/40326912
https://lirias.kuleuven.be/handle/20.500.12942/765604
https://doi.org/10.1080/21678421.2025.2450805

Natural history of the revised ALS functional rating scale and its association with survival: the PRECISION-ALS Extant Study

Authors: Ruben P. A. van Eijk Daphne N. Weemering Sarah Opie-Martin et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 26:30-40

Subject Terms: Male, Adult, Clinical Neurology, DIAGNOSIS, survival, Severity of Illness Index, AMYOTROPHIC-LATERAL-SCLEROSIS, Cohort Studies, DESIGN, ALSFRS-R, Humans, Longitudinal Studies, joint model, Aged, Science & Technology, DISEASE PROGRESSION, Amyotrophic Lateral Sclerosis, 1103 Clinical Sciences, Middle Aged, Survival Rate, 3209 Neurosciences, Disease Progression, Female, Neurosciences & Neurology, ALS, 1109 Neurosciences, Life Sciences & Biomedicine, CLINICAL-TRIALS

Access URL: https://pubmed.ncbi.nlm.nih.gov/40326917

Examining changing working status and caregiver assistance in amyotrophic lateral sclerosis (ALS) using large-scale European databases as part of PRECISION-ALS

Authors: Mcdonough, Harry Mcfarlane, Robert Puchades, Alejandro Caravaca et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 26:20-29

Subject Terms: Male, Employment, Adult, STRAIN, Databases, Factual, IMPACT, Clinical Neurology, NEEDS, DISEASE, Cohort Studies, EMPLOYMENT STATUS, QUALITY-OF-LIFE, Humans, Longitudinal Studies, caregiver, Aged, Science & Technology, socio economic, Amyotrophic Lateral Sclerosis, working status, 1103 Clinical Sciences, Middle Aged, DEPRESSION, TIME, Europe, Caregivers, employment, 3209 Neurosciences, Female, Neurosciences & Neurology, BURDEN, 1109 Neurosciences, Life Sciences & Biomedicine

Access URL: https://pubmed.ncbi.nlm.nih.gov/40326913

Real-world prognostic role of riluzole use in ALS: a multi-center study from PRECISION-ALS

Authors: Vasta, Rosario Ombelet, Fouke Hobin, Frederik et al.

Source: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 26:50-60

Subject Terms: Male, Adult, Clinical Neurology, PROGRESSION, Kaplan-Meier Estimate, survival, AMYOTROPHIC-LATERAL-SCLEROSIS, Humans, Retrospective Studies, Aged, Science & Technology, Riluzole, Amyotrophic Lateral Sclerosis, 1103 Clinical Sciences, Middle Aged, Prognosis, riluzole, Neuroprotective Agents, Treatment Outcome, 3209 Neurosciences, SURVIVAL, Disease Progression, epidemiology, Female, Neurosciences & Neurology, prognosis, 1109 Neurosciences, Life Sciences & Biomedicine

Access URL: https://pubmed.ncbi.nlm.nih.gov/40326914
https://lirias.kuleuven.be/handle/20.500.12942/771467
https://doi.org/10.1080/21678421.2025.2472889