Výsledky vyhľadávania - "Neuroprotective Agents chemical synthesis"

Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment

Autori: Montanari S. Mahmoud A. M. Pruccoli L. a ďalší

Zdroj: European journal of medicinal chemistry 178 (2019): 243–258. doi:10.1016/j.ejmech.2019.05.080
info:cnr-pdr/source/autori:Montanari, Serena; Mahmoud, Ali Mokhtar; Pruccoli, Letizia; Rabbito, Alessandro; Naldi, Marina; Petralla, Sabrina; Moraleda, Ignacio; Bartolini, Manuela; Monti, Barbara; Iriepa, Isabel; Belluti, Federica; Gobbi, Silvia; Di Marzo, Vincenzo; Bisi, Alessandra; Tarozzi, Andrea; Ligresti, Alessia; Rampa, Angela/titolo:Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment/doi:10.1016%2Fj.ejmech.2019.05.080/rivista:European journal of medicinal chemistry/anno:2019/pagina_da:243/pagina_a:258/intervallo_pagine:243–258/volume:178
European Journal of Medicinal Chemistry

Predmety: Neuroprotective agents - chemical synthesis, 0301 basic medicine, Benzofurans - chemistry, Anti-inflammatory M2 phenotype, Aβ peptide, Benzofuran scaffold, CB receptors, MTDL, Neuroprotection, Acetylcholinesterase, Alzheimer Disease, Amyloid beta-Peptides, Animals, Benzofurans, Butyrylcholinesterase, CHO Cells, Catalytic Domain, Cell Line, Tumor, Cholinesterase Inhibitors, Cricetulus, Drug Design, Humans, Immunologic Factors, Mice, Microglia, Molecular Docking Simulation, Neuroprotective Agents, Peptide Fragments, Protein Binding, Receptor, Cannabinoid, CB1, Receptor, Cannabinoid, CB2, Small Molecule Libraries, Neuroprotective agents - chemistry, Cholinesterase inhibitors - chemistry, Neuroprotective agents - pharmacology, Molecular docking simulation, Small molecule libraries - chemical synthesis, Benzofurans - pharmacology, 0303 health sciences, Small molecule libraries - pharmacology, CHO cells, Neuroprotective agents - metabolism, cannabinoid, 3. Good health, Alzheimer disease - drug therapy, Acetylcholinesterase - metabolism, CB2 - metabolism, CB1 - metabolism, Receptor, tumor, Small molecule libraries - metabolism, Benzofurans - metabolism, Cholinesterase inhibitors - chemical synthesis, 03 medical and health sciences, Protein binding, Butyrylcholinesterase - chemistry, A beta peptide, Small molecule libraries - chemistry, Benzofurans - chemical synthesis, Amyloid beta-peptides - antagonists & inhibitors, Microglia - drug effects, Catalytic domain, Peptide fragments - antagonists & inhibitors, Cholinesterase inhibitors - pharmacology, Cholinesterase inhibitors - metabolism, Cell line

Popis súboru: application/pdf

Prístupová URL adresa: https://cris.unibo.it/bitstream/11585/700770/5/benzo%20AM%20.pdf
https://pubmed.ncbi.nlm.nih.gov/31185414
https://pubmed.ncbi.nlm.nih.gov/31185414/
https://cris.unibo.it/handle/11585/700770
https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=201902215229988983
https://www.sciencedirect.com/science/article/pii/S0223523419304982
https://www.ncbi.nlm.nih.gov/pubmed/31185414
https://hdl.handle.net/20.500.14243/366587
https://doi.org/10.1016/j.ejmech.2019.05.080

Synthesis of new proteomimetic quinazolinone alkaloids and evaluation of their neuroprotective and antitumor effects

Autori: Long, S Resende, D Kijjoa, A a ďalší

Prispievatelia: Long, S Resende, D Kijjoa, A a ďalší

Predmety: Antitumor, Enantioselectivity, Fiscalin B, Fumiquinazoline, Neuroprotection, Quinazolinones, Alkaloids / chemical synthesis, Alkaloids / pharmacology, Antineoplastic Agents / chemical synthesis, Antineoplastic Agents / pharmacology, Cell Line, Tumor, Epithelial Cells / drug effects, Epithelial Cells / metabolism, Epithelial Cells / pathology, Humans, Inhibitory Concentration 50, Molecular Structure, Neurons / drug effects, Neurons / metabolism, Neurons / pathology, Neuroprotective Agents / chemical synthesis, Neuroprotective Agents / pharmacology, Peptidomimetics / chemical synthesis, Peptidomimetics / pharmacology, Quinazolinones / chemical synthesis, Quinazolinones / pharmacology, Structure-Activity Relationship

Popis súboru: application/pdf

Relation: info:eu-repo/grantAgreement/FCT/5876/147268/PT; Molecules, vol.24(3):534; https://www.mdpi.com/1420-3049/24/3/534; https://hdl.handle.net/10216/136283

Dostupnosť: https://hdl.handle.net/10216/136283
https://doi.org/10.3390/molecules24030534

ChemInform Abstract: Synthesis of 6,6‐Dicarboxy‐3,4‐methano‐L‐proline, a New Constrained Glutamate Analogue Endowed with Neuroprotective Properties

Autori: MARINOZZI, Maura NATALINI, Benedetto COSTANTINO, Gabriele a ďalší

Prispievatelia: MARINOZZI, Maura NATALINI, Benedetto COSTANTINO, Gabriele a ďalší

Zdroj: ChemInform. 27

Predmety: Cerebral Cortex, Proline, 01 natural sciences, 3. Good health, 0104 chemical sciences, Mice, Neuroprotective Agents, Receptors, Glutamate, Pregnancy, Animals, Female, animals, cells cultured, cerebral cortex drug effects, female, mice, neuroprotective agents chemical synthesis/pharmacology, pregnancy, proline analogs /&/ derivatives/chemical synthesis/pharmacology, receptors glutamate drug effects, Cells, Cultured

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/8857207
http://onlinelibrary.wiley.com/doi/10.1002/chin.199630244/full
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=A1996UB34800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=0c7ff228ccbaaa74236f48834a34396a
https://hdl.handle.net/11573/461027
https://hdl.handle.net/11391/913700

Synthesis of 6,6-dicarboxy-3,4-methano-L-proline, a new constrained glutamate analog endowed with neuroprotective properties

Autori: M. Marinozzi B. Natalini G. Costantino a ďalší

Prispievatelia: M. Marinozzi B. Natalini G. Costantino a ďalší

Predmety: animal, cells cultured, cerebral cortex drug effect, female, mice, neuroprotective agents chemical synthesis/pharmacology, pregnancy, proline analogs /&/ derivatives/chemical synthesis/pharmacology, receptors glutamate drug effects

Popis súboru: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/8857207; info:eu-repo/semantics/altIdentifier/wos/WOS:A1996UB34800005; volume:51; issue:2; firstpage:121; lastpage:124; numberofpages:4; journal:IL FARMACO; http://hdl.handle.net/11573/461027; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=A1996UB34800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=0c7ff228ccbaaa74236f48834a34396a

Dostupnosť: http://hdl.handle.net/11573/461027
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=A1996UB34800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=0c7ff228ccbaaa74236f48834a34396a
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029932576&partnerID=65&md5=cf17198db94c6fa2ac77760abede1f2c