Výsledky vyhľadávania - "Neoplastic Stem Cells pathology"

Epigenomic disorder and partial EMT impair luminal progenitor integrity in Brca1-associated breast tumorigenesis

Autori: Landragin, Camille Saichi, Melissa Laisné, Marthe a ďalší

Prispievatelia: Landragin, Camille Saichi, Melissa Laisné, Marthe a ďalší

Zdroj: Mol Cancer
Molecular Cancer, Vol 24, Iss 1, Pp 1-18 (2025)
Molecular cancer, vol. 24, no. 1, pp. 127

Predmety: Epigenomics, Epithelial-Mesenchymal Transition, BRCA1 Protein, Carcinogenesis, Research, Humans, BRCA1 Protein/genetics, BRCA1 Protein/metabolism, Female, Epithelial-Mesenchymal Transition/genetics, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Breast Neoplasms/metabolism, Animals, Mice, Carcinogenesis/genetics, Epigenomics/methods, Mutation, Cell Transformation, Neoplastic/genetics, Gene Expression Regulation, Neoplastic, Neoplastic Stem Cells/metabolism, Neoplastic Stem Cells/pathology, Tumor Microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Breast Neoplasms, [SDV.GEN] Life Sciences [q-bio]/Genetics, [SDV] Life Sciences [q-bio], Cell Transformation, Neoplastic, [SDV.CAN] Life Sciences [q-bio]/Cancer, Neoplastic Stem Cells, RC254-282

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40289099
https://doaj.org/article/9577a552c5f9402794c0a44a5434e8f7
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7DF1ACD126EB3
https://serval.unil.ch/notice/serval:BIB_7DF1ACD126EB
https://serval.unil.ch/resource/serval:BIB_7DF1ACD126EB.P001/REF.pdf

Asciminib antagonizes transplantable BCR::ABL1-positive lymphoid blast crisis in vivo by targeting malignant stem cells

Autori: Nicolas Chatain Julian Baumeister Marcelo A. Szymanski de Toledo a ďalší

Zdroj: Leukemia
Leukemia : normal and malignant hemopoiesis 38(8), 1825-1830 (2024). doi:10.1038/s41375-024-02320-9

Predmety: Niacinamide, Letter, Fusion Proteins, bcr-abl, 3. Good health, Mice, Neoplastic Stem Cells/pathology [MeSH], Proto-Oncogene Proteins c-abl/genetics [MeSH], Pyrazoles/therapeutic use [MeSH], Fusion Proteins, bcr-abl/antagonists, Neoplastic Stem Cells/metabolism [MeSH], 631/67/395, 13/100, Blast Crisis/drug therapy [MeSH], Niacinamide/analogs, letter, 13/31, 631/67/1059/602, Fusion Proteins, bcr-abl/genetics [MeSH], Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy [MeSH], Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology [MeSH], Neoplastic Stem Cells/drug effects [MeSH], Protein Kinase Inhibitors/pharmacology [MeSH], Humans [MeSH], Pyrazoles/pharmacology [MeSH], 692/308/2778, Animals [MeSH], Proto-Oncogene Proteins c-abl/metabolism [MeSH], 64/60, Protein Kinase Inhibitors/therapeutic use [MeSH], Mice [MeSH], 45/23, Blast Crisis/pathology [MeSH], Proto-Oncogene Proteins c-abl/antagonists, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Neoplastic Stem Cells, Humans, Animals, Pyrazoles, Blast Crisis, Proto-Oncogene Proteins c-abl, Protein Kinase Inhibitors

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38906962
https://repository.publisso.de/resource/frl:6491114
https://publications.rwth-aachen.de/record/989174

LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression

Autori: Weiwei Chen Fei Wang Xinyuan Yu a ďalší

Zdroj: Oncogene

Predmety: Male, Cancer Research, Lung Neoplasms, Lysine, Intracellular Signaling Peptides and Proteins, Nuclear Proteins, Zinc Finger Protein Gli2, Prognosis, Molecular Processes and Therapies [Topic 2], Article, 3. Good health, Gene Expression Regulation, Neoplastic, Histones, Gene Expression Regulation, Neoplastic [MeSH], Cell Line, Tumor [MeSH], Carcinoma, Non-Small-Cell Lung/genetics [MeSH], Neoplastic Stem Cells/pathology [MeSH], Histones/genetics [MeSH], Lung Neoplasms/genetics [MeSH], RNA, Long Noncoding/genetics [MeSH], 38/90, Zinc Finger Protein Gli2/genetics [MeSH], 13/51, Intracellular Signaling Peptides and Proteins [MeSH], Male [MeSH], Lysine/analogs, 13/100, 45/15, 631/67/1612/1350, 38/1, 631/80/304, 13/1, Carcinoma, Non-Small-Cell Lung/pathology [MeSH], Female [MeSH], Cell Proliferation [MeSH], Humans [MeSH], 42/109, 64/60, Nuclear Proteins/genetics [MeSH], Prognosis [MeSH], Lung Neoplasms/pathology [MeSH], 59, article, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Neoplastic Stem Cells, Humans, Female, RNA, Long Noncoding, Cell Proliferation

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37950038
https://edoc.mdc-berlin.de/id/eprint/23863/1/23863oa.pdf
https://repository.publisso.de/resource/frl:6496289

Membrane RRM2-positive cells represent a malignant population with cancer stem cell features in intrahepatic cholangiocarcinoma

Autori: Yongzhi Zhao Shuting Xue Danduo Wei a ďalší

Zdroj: J Exp Clin Cancer Res
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)

Predmety: Male, Tumor heterogeneity, Ribonucleoside Diphosphate Reductase, Research, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cholangiocarcinoma, Mice, Bile Duct Neoplasms, Cell Line, Tumor, Female [MeSH], Cell Line, Tumor [MeSH], Neoplastic Stem Cells/pathology [MeSH], Humans [MeSH], Bile Duct Neoplasms/metabolism [MeSH], Cell membrane localization, Bile Duct Neoplasms/pathology [MeSH], Ribonucleoside Diphosphate Reductase/genetics [MeSH], Neoplastic Stem Cells/metabolism [MeSH], Animals [MeSH], Intrahepatic cholangiocarcinoma, Cholangiocarcinoma/metabolism [MeSH], Mice [MeSH], Male [MeSH], Ribonucleoside Diphosphate Reductase/metabolism [MeSH], Cholangiocarcinoma/pathology [MeSH], Biomarkers, Tumor/metabolism [MeSH], RRM2, Cholangiocarcinoma/genetics [MeSH], Bile Duct Neoplasms/genetics [MeSH], Neoplastic Stem Cells, Biomarkers, Tumor, Humans, Animals, Female, RC254-282

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39243109
https://doaj.org/article/2b48bf5aea52498e891360b6ade86741
https://repository.publisso.de/resource/frl:6507276

Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models

Autori: Larrue, Clément Mouche, Sarah Angelino, Paolo a ďalší

Zdroj: Science Translational Medicine. 16

Predmety: 0301 basic medicine, 0303 health sciences, Iron / metabolism, Iron, Nuclear Receptor Coactivators, Neoplastic Stem Cells / metabolism, 616.07, Neoplastic Stem Cells / pathology, Xenograft Model Antitumor Assays, Leukemia, Myeloid, Acute, Mice, 03 medical and health sciences, Leukemia, Myeloid, Acute / pathology, Nuclear Receptor Coactivators / metabolism, Cell Line, Tumor, Leukemia, Myeloid, Acute / metabolism, Ferritins, Neoplastic Stem Cells, Autophagy, Humans, Animals, Ferritins / metabolism

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39047119
https://archive-ouverte.unige.ch/unige:181666
https://doi.org/10.1126/scitranslmed.adk1731

Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres

Autori: Seo Jin, Kim Soo Jeong, Park Junseong, Park a ďalší

Prispievatelia: Seo Jin, Kim Soo Jeong, Park Junseong, Park a ďalší

Zdroj: Journal of Neuro-Oncology. 160:677-689

Predmety: Glioblastoma* / metabolism, 0301 basic medicine, Glucosephosphate Dehydrogenase / metabolism, Neoplastic Stem Cells / drug effects, Neoplastic Stem Cells / metabolism, Glucosephosphate Dehydrogenase, Neoplastic Stem Cells / pathology, Cell Line, Glucosephosphate Dehydrogenase / genetics, Mice, 03 medical and health sciences, Carnitine palmitoyltransferase 1A, Cell Line, Tumor, Animals, Humans, Glucosephosphate Dehydrogenase / antagonists & inhibitors, Etomoxir, Glucose-6-phosphate dehydrogenase, Carnitine O-Palmitoyltransferase / metabolism, 0303 health sciences, Tumor, Carnitine O-Palmitoyltransferase / genetics, Carnitine O-Palmitoyltransferase, Glioblastoma* / drug therapy, Dehydroepiandrosterone, Dehydroepiandrosterone / therapeutic use, 3. Good health, Glioblastoma* / genetics, Carnitine O-Palmitoyltransferase / antagonists & inhibitors, Neoplastic Stem Cells, Glioblastoma

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36396930

Alpha-6 integrin deletion delays the formation of Brca1/p53-deficient basal-like breast tumors by restricting luminal progenitor cell expansion

Autori: Faraldo, Marisa M. Romagnoli, Mathilde Wallon, Loane a ďalší

Zdroj: Breast Cancer Res
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)

Predmety: 0301 basic medicine, 0303 health sciences, BRCA1 Protein, Research, Stem Cells, Luminal progenitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Breast Neoplasms, Integrin alpha6, 3. Good health, Mice, 03 medical and health sciences, Cell Transformation, Neoplastic, Gene Deletion [MeSH], Female [MeSH], Cell Proliferation [MeSH], Cell Transformation, Neoplastic/metabolism [MeSH], Neoplastic Stem Cells/pathology [MeSH], Laminin-binding integrins, BRCA1 Protein/genetics [MeSH], Humans [MeSH], Integrin alpha6/genetics [MeSH], Breast Neoplasms/genetics [MeSH], Cell Transformation, Neoplastic/genetics [MeSH], Stem Cells/metabolism [MeSH], Tumor Suppressor Protein p53/metabolism [MeSH], Breast Neoplasms/metabolism [MeSH], Neoplastic Stem Cells/metabolism [MeSH], Animals [MeSH], Tumor Suppressor Protein p53/genetics [MeSH], Brca1/p53-deficient tumors, Mice [MeSH], BRCA1 Protein/metabolism [MeSH], Integrin alpha6/metabolism [MeSH], Breast Neoplasms/pathology [MeSH], Neoplastic Stem Cells, Animals, Humans, Female, Tumor Suppressor Protein p53, RC254-282, Gene Deletion, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38835038
https://doaj.org/article/28d9748dffe74913bc09ffa1e4f1d948
https://repository.publisso.de/resource/frl:6498211

CAR-T overdrive: harnessing inosine for metabolic rewiring and stemness induction

Autori: Martí Farrera-Sal Michael Schmueck-Henneresse

Zdroj: Signal Transduct Target Ther
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)

Predmety: QH301-705.5, Immunotherapy, Adoptive [MeSH], Research Highlight, Neoplastic Stem Cells/pathology [MeSH], Humans [MeSH], Receptors, Chimeric Antigen/immunology [MeSH], Neoplastic Stem Cells/metabolism [MeSH], Animals [MeSH], Receptors, Chimeric Antigen/genetics [MeSH], Inosine/metabolism [MeSH], research-highlight, Inosine/genetics [MeSH], 692/4028/67, 631/250/251, 631/67/580, Medicine, Biology (General)

Prístupová URL adresa: https://doaj.org/article/f5f2fe4dc048440c9e96941a56d8d0ef
https://repository.publisso.de/resource/frl:6494712

Knockdown of the prognostic cancer stem cell marker Musashi-1 decreases radio-resistance while enhancing apoptosis in hormone receptor-positive breast cancer cells via p21WAF1/CIP1

Autori: Fabian M. Troschel Heike Palenta Katrin Borrmann a ďalší

Prispievatelia: Fabian M. Troschel Heike Palenta Katrin Borrmann a ďalší

Zdroj: J Cancer Res Clin Oncol

Predmety: Cyclin-Dependent Kinase Inhibitor p21, Down-Regulation, RNA-binding proteins, Apoptosis, Breast Neoplasms, Nerve Tissue Proteins, Radiation Tolerance, Radio-resistance, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Cell Proliferation/physiology [MeSH], Aged [MeSH], Neoplastic Stem Cells/pathology [MeSH], Nerve Tissue Proteins/metabolism [MeSH], Apoptosis/physiology [MeSH], Neoplastic Stem Cells/metabolism [MeSH], Breast Neoplasms/radiotherapy [MeSH], Radiation Tolerance [MeSH], RNA-Binding Proteins/biosynthesis [MeSH], MCF-7 Cells [MeSH], p21, Cyclin-Dependent Kinase Inhibitor p21/biosynthesis [MeSH], Breast Neoplasms/pathology [MeSH], Cyclin-Dependent Kinase Inhibitor p21/metabolism [MeSH], Female [MeSH], Down-Regulation [MeSH], Original Article – Cancer Research, Nerve Tissue Proteins/biosynthesis [MeSH], RNA-Binding Proteins/metabolism [MeSH], Humans [MeSH], Gene Knockdown Techniques [MeSH], Breast Neoplasms/metabolism [MeSH], Nerve Tissue Proteins/genetics [MeSH], Musashi-1, RNA-Binding Proteins/genetics [MeSH], Prognosis [MeSH], Neoplastic Stem Cells/radiation effects [MeSH], Humans, Aged, Cell Proliferation, RNA-Binding Proteins, Prognosis, 3. Good health, Gene Knockdown Techniques, MCF-7 Cells, Neoplastic Stem Cells, Female

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00432-021-03743-y.pdf
https://pubmed.ncbi.nlm.nih.gov/34291358
https://link.springer.com/article/10.1007/s00432-021-03743-y
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484224
https://link.springer.com/content/pdf/10.1007/s00432-021-03743-y.pdf
https://pubmed.ncbi.nlm.nih.gov/34291358/
https://repository.publisso.de/resource/frl:6449820

Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes

Autori: Feyza Gul Ozbay Aysegul Uner Dorina Esendagli a ďalší

Zdroj: Cancer Immunol Immunother

Predmety: Cancer Research, Lung Neoplasms, Apoptosis, Mesenchymal Stem Cells, CD8-Positive T-Lymphocytes, Programmed Cell Death 1 Ligand 2 Protein, Small Cell Lung Carcinoma, B7-H1 Antigen, 3. Good health, 03 medical and health sciences, Hyaluronan Receptors, 0302 clinical medicine, Neoplastic Stem Cells, Tumor Cells, Cultured, Humans, Neoplastic Stem Cells/pathology [MeSH], Cancer stem cell, Neoplastic Stem Cells/metabolism [MeSH], Apoptosis [MeSH], B7-H1 Antigen/metabolism [MeSH], Original Article, Tumor Cells, Cultured [MeSH], TIM-3, Lung Neoplasms/immunology [MeSH], Small Cell Lung Carcinoma/pathology [MeSH], CD8-Positive T-Lymphocytes/immunology [MeSH], LAG3, Mesenchymal Stem Cells/immunology [MeSH], Cell Proliferation [MeSH], Mesenchymal Stem Cells/pathology [MeSH], T-Lymphocytes, Cytotoxic/immunology [MeSH], Neoplastic Stem Cells/immunology [MeSH], Humans [MeSH], Small Cell Lung Carcinoma/metabolism [MeSH], Hyaluronan Receptors/metabolism [MeSH], Programmed Cell Death 1 Ligand 2 Protein/metabolism [MeSH], PD-1, Mesenchymal Stem Cells/metabolism [MeSH], Immunotherapy, Lung Neoplasms/pathology [MeSH], Lung cancer, Lung Neoplasms/metabolism [MeSH], Small Cell Lung Carcinoma/immunology [MeSH], Cell Proliferation, T-Lymphocytes, Cytotoxic

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00262-021-02998-1.pdf
https://pubmed.ncbi.nlm.nih.gov/34228218
https://link.springer.com/content/pdf/10.1007/s00262-021-02998-1.pdf
https://pubmed.ncbi.nlm.nih.gov/34228218/
https://europepmc.org/article/MED/34228218
https://www.ncbi.nlm.nih.gov/pubmed/34228218
https://link.springer.com/article/10.1007/s00262-021-02998-1
https://edoc.mdc-berlin.de/20413/
https://edoc.mdc-berlin.de/id/eprint/20413/2/20413suppl.pdf
https://repository.publisso.de/resource/frl:6451417
https://aperta.ulakbim.gov.tr/record/239058

Differential expression of stem cell markers in proliferating cells in glioma

Autori: Marten Rehfeld Jakob Matschke Christian Hagel a ďalší

Zdroj: J Cancer Res Clin Oncol

Predmety: 0301 basic medicine, 0303 health sciences, Brain Neoplasms, Lewis X Antigen, RNA-Binding Proteins, Nerve Tissue Proteins, Glioma, 3. Good health, Gene Expression Regulation, Neoplastic, Nestin, 03 medical and health sciences, Hyaluronan Receptors, Gene Expression Regulation, Neoplastic [MeSH], Lewis X Antigen/metabolism [MeSH], Cell Proliferation [MeSH], Glioma/metabolism [MeSH], Original Article – Cancer Research, Neoplastic Stem Cells/pathology [MeSH], RNA-Binding Proteins/metabolism [MeSH], Humans [MeSH], Nerve Tissue Proteins/metabolism [MeSH], Nestin/metabolism [MeSH], AC133 Antigen/metabolism [MeSH], Hyaluronan Receptors/metabolism [MeSH], Stem cells, Expression profile, Neoplastic Stem Cells/metabolism [MeSH], Glioblastoma, Glioma/pathology [MeSH], Biomarkers, Tumor/metabolism [MeSH], Proliferating cells, Ki67, Brain Neoplasms/metabolism [MeSH], Brain Neoplasms/pathology [MeSH], Biomarkers, Tumor, Neoplastic Stem Cells, Humans, AC133 Antigen, Cell Proliferation

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00432-021-03704-5.pdf
https://pubmed.ncbi.nlm.nih.gov/34170383
https://link.springer.com/content/pdf/10.1007/s00432-021-03704-5.pdf
https://europepmc.org/article/MED/34170383
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397690
https://link.springer.com/article/10.1007/s00432-021-03704-5
https://pubmed.ncbi.nlm.nih.gov/34170383/
https://repository.publisso.de/resource/frl:6449844

Oct4 confers stemness and radioresistance to head and neck squamous cell carcinoma by regulating the homologous recombination factors PSMC3IP and RAD54L

Autori: Anna Dubrovska Vasyl Lukiyanchuk Ina Kurth a ďalší

Zdroj: Oncogene

Predmety: Aged [MeSH], Octamer Transcription Factor-3/genetics [MeSH], Neoplastic Stem Cells/pathology [MeSH], Squamous Cell Carcinoma of Head and Neck/pathology [MeSH], Prognostic markers, Head and Neck Neoplasms/genetics [MeSH], Trans-Activators/genetics [MeSH], DNA-Binding Proteins/genetics [MeSH], DNA Helicases/genetics [MeSH], Male [MeSH], Head and neck cancer, DNA Damage/genetics [MeSH], Cancer stem cells, Female [MeSH], Radiation Tolerance/genetics [MeSH], Oncogenes, Adult [MeSH], Humans [MeSH], Homologous Recombination/genetics [MeSH], Middle Aged [MeSH], Squamous Cell Carcinoma of Head and Neck/genetics [MeSH], Nuclear Proteins/genetics [MeSH], Article, Young Adult [MeSH], Gene Expression Regulation, Neoplastic/genetics [MeSH], Head and Neck Neoplasms/pathology [MeSH], Adult, Male, 0301 basic medicine, 0303 health sciences, Squamous Cell Carcinoma of Head and Neck, DNA Helicases, Nuclear Proteins, Middle Aged, Radiation Tolerance, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Young Adult, 03 medical and health sciences, Head and Neck Neoplasms, Neoplastic Stem Cells, Trans-Activators, Humans, Female, Homologous Recombination, Octamer Transcription Factor-3, Aged, DNA Damage

Prístupová URL adresa: https://www.nature.com/articles/s41388-021-01842-1.pdf
https://pubmed.ncbi.nlm.nih.gov/34079088
https://www.nature.com/articles/s41388-021-01842-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211562
https://pubmed.ncbi.nlm.nih.gov/34079088/
https://www.nature.com/articles/s41388-021-01842-1.pdf
https://europepmc.org/article/MED/34079088
https://repository.publisso.de/resource/frl:6443694

Low CtBP2 expression is associated with a stem cell-like signature and adverse clinical outcome in childhood B-cell lymphoblastic leukemia

Autori: Joseph L. Wiemels Sun-Hee Kim Hong Hoe Koo a ďalší

Prispievatelia: Joseph L. Wiemels Sun-Hee Kim Hong Hoe Koo a ďalší

Zdroj: Leukemia. 35:2684-2687

Predmety: Adult, Male, 0301 basic medicine, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy, Adolescent, Co-Repressor Proteins / metabolism, Neoplastic Stem Cells / drug effects, Neoplastic Stem Cells / metabolism, Young Adult, 03 medical and health sciences, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Humans, Preschool, Child, Tumor / metabolism, Neoplastic Stem Cells / pathology, 0303 health sciences, Antineoplastic Combined Chemotherapy Protocols / therapeutic use, Infant, Prognosis, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology, Survival Rate, Alcohol Oxidoreductases, Child, Preschool, Neoplastic Stem Cells, Alcohol Oxidoreductases / metabolism, Female, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / mortality, Co-Repressor Proteins, Biomarkers, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / metabolism, Follow-Up Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33580202
https://pubmed.ncbi.nlm.nih.gov/33580202/
https://www.ncbi.nlm.nih.gov/pubmed/33580202
https://www.nature.com/articles/s41375-021-01151-2.pdf
https://www.scilit.net/article/90414d847719fc9b6b53964a232e1f4d?action=show-references
https://www.nature.com/articles/s41375-021-01151-2
https://ir.ymlib.yonsei.ac.kr/handle/22282913/185444

IL‐6 and IL‐8, secreted by myofibroblasts in the tumor microenvironment, activate HES1 to expand the cancer stem cell population in early colorectal tumor

Autori: Bun Kim Yoojeong Seo Ji‐Hee Kwon a ďalší

Prispievatelia: Bun Kim Yoojeong Seo Ji‐Hee Kwon a ďalší

Zdroj: Molecular Carcinogenesis. 60:188-200

Predmety: Transcription Factor HES-1 / metabolism, Tumor Microenvironment / drug effects, STAT3 Transcription Factor, 0301 basic medicine, Interleukin-6 / metabolism, Myofibroblasts / metabolism, cancer stem cell, STAT3 Transcription Factor / antagonists & inhibitors, STAT3 Transcription Factor / metabolism, Transcription Factor HES-1 / genetics, Neoplastic Stem Cells / drug effects, Neoplastic Stem Cells / metabolism, colorectal cancer, Organoids / pathology, Colorectal Neoplasms / genetics, 03 medical and health sciences, Tumor Microenvironment, Humans, Myofibroblasts, Colorectal Neoplasms / pathology, Neoplastic, Neoplastic Stem Cells / pathology, IL-6, 0303 health sciences, IL-8, Interleukin-6, Myofibroblasts / pathology, Interleukin-8, myofibroblast, Culture Media, 3. Good health, Gene Expression Regulation, Neoplastic, Organoids, Gene Expression Regulation, Culture Media, Conditioned, Conditioned / pharmacology, HES1, Neoplastic Stem Cells, Transcription Factor HES-1, Interleukin-8 / metabolism, Caco-2 Cells, Colorectal Neoplasms / metabolism, Colorectal Neoplasms

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33544929
https://www.ncbi.nlm.nih.gov/pubmed/33544929
https://europepmc.org/article/MED/33544929
https://ir.ymlib.yonsei.ac.kr/handle/22282913/183996
https://yonsei.pure.elsevier.com/en/publications/il-6-and-il-8-secreted-by-myofibroblasts-in-the-tumor-microenviro
https://onlinelibrary.wiley.com/doi/10.1002/mc.23283
https://pubmed.ncbi.nlm.nih.gov/33544929/

Role of cancer stem cell markers ALDH1, BCL11B, BMI-1, and CD44 in the prognosis of advanced HNSCC

Autori: Mark Jakob Kariem Sharaf Markus Schirmer a ďalší

Prispievatelia: Mark Jakob Kariem Sharaf Markus Schirmer a ďalší

Zdroj: Strahlenther Onkol

Predmety: Male, Polycomb Repressive Complex 1, 0301 basic medicine, Squamous Cell Carcinoma of Head and Neck, Tumor Suppressor Proteins, Middle Aged, Female [MeSH], Molecular markers, Primary radiochemotherapy, Aged [MeSH], Neoplastic Stem Cells/pathology [MeSH], Squamous Cell Carcinoma of Head and Neck/pathology [MeSH], Humans [MeSH], Squamous Cell Carcinoma of Head and Neck/diagnosis [MeSH], Survival Analysis [MeSH], Retrospective Studies [MeSH], Tumor Suppressor Proteins/analysis [MeSH], Middle Aged [MeSH], Head and Neck Neoplasms/diagnosis [MeSH], Original Article, Hyaluronan Receptors/analysis [MeSH], Survival, Male [MeSH], Head and neck cancer, Prognosis [MeSH], Aldehyde Dehydrogenase 1 Family/analysis [MeSH], Surgical treatment, Head and Neck Neoplasms/pathology [MeSH], Polycomb Repressive Complex 1/analysis [MeSH], Repressor Proteins/analysis [MeSH], Prognosis, Survival Analysis, Aldehyde Dehydrogenase 1 Family, 3. Good health, Repressor Proteins, 03 medical and health sciences, Hyaluronan Receptors, 0302 clinical medicine, Head and Neck Neoplasms, Neoplastic Stem Cells, Humans, Female, Aged, Retrospective Studies

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00066-020-01653-5.pdf
https://pubmed.ncbi.nlm.nih.gov/32588101
https://www.ncbi.nlm.nih.gov/pubmed/32588101
https://pubmed.ncbi.nlm.nih.gov/32588101/
http://www.ncbi.nlm.nih.gov/pubmed/32588101
https://epub.ub.uni-muenchen.de/73192/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892527
https://link.springer.com/content/pdf/10.1007/s00066-020-01653-5.pdf
https://resolver.sub.uni-goettingen.de/purl?gro-2/81877
https://repository.publisso.de/resource/frl:6443260
https://epub.ub.uni-muenchen.de/73192/

Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells.

Autori: Alberti, L. Losi, L. Leyvraz, S. a ďalší

Predmety: ATP-Binding Cassette Transporters/genetics, ATP-Binding Cassette Transporters/metabolism, Antigens, CD44/genetics, CD44/metabolism, Biomarkers, Tumor/genetics, Tumor/metabolism, Cell Line, Tumor, Cell Movement, Cell Proliferation, DNA-Binding Proteins/antagonists & inhibitors, DNA-Binding Proteins/genetics, Epithelial Cells/metabolism, Epithelial Cells/pathology, Epithelial-Mesenchymal Transition/genetics, Gene Expression Regulation, Neoplastic, Homeodomain Proteins/genetics, Homeodomain Proteins/metabolism, Humans, Isoenzymes/genetics, Isoenzymes/metabolism, Neoplasm Proteins/genetics, Neoplasm Proteins/metabolism, Neoplastic Stem Cells/metabolism, Neoplastic Stem Cells/pathology, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism

Popis súboru: application/pdf

Relation: PLoS ONE; https://iris.unil.ch/handle/iris/87738; serval:BIB_127E6A07B81B; 000358198700081

Dostupnosť: https://iris.unil.ch/handle/iris/87738
https://doi.org/10.1371/journal.pone.0132977

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.

Autori: Cagnetta, A. Soncini, D. Orecchioni, S. a ďalší

Predmety: Animals, Antineoplastic Agents/pharmacology, Ataxia Telangiectasia Mutated Proteins/metabolism, Biomarkers, Tumor, Cell Line, Cell Proliferation/drug effects, Checkpoint Kinase 2/metabolism, DNA Damage/drug effects, DNA Repair, Disease Models, Animal, Enzyme Activation, Gene Expression, Genomic Instability, Humans, Immunophenotyping, Leukemia, Myeloid, Acute/genetics, Acute/metabolism, Acute/mortality, Acute/pathology, Mice, Neoplastic Stem Cells/metabolism, Neoplastic Stem Cells/pathology, Prognosis, Protein Binding, Sirtuins/genetics, Sirtuins/metabolism

Popis súboru: application/pdf

Relation: Haematologica; https://iris.unil.ch/handle/iris/55965; serval:BIB_0A0458D4A8E8; 000418944500022

Dostupnosť: https://iris.unil.ch/handle/iris/55965
https://doi.org/10.3324/haematol.2017.176248

A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma.

Autori: De Vito, C. Riggi, N. Cornaz, S. a ďalší

Predmety: Animals, Cell Line, Tumor, Cells, Cultured, Child, Preschool, Embryonic Stem Cells/metabolism, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Induced Pluripotent Stem Cells/metabolism, Male, Mesenchymal Stromal Cells/metabolism, Mice, Inbred NOD, Knockout, SCID, MicroRNAs/genetics, Mutation, Neoplasms, Experimental/genetics, Experimental/metabolism, Experimental/pathology, Neoplastic Stem Cells/metabolism, Neoplastic Stem Cells/pathology, RNA-Binding Proteins/genetics, RNA-Binding Proteins/metabolism

Relation: Cancer Cell; https://iris.unil.ch/handle/iris/55949; serval:BIB_5D2E37405825; 000305263100012

Dostupnosť: https://iris.unil.ch/handle/iris/55949
https://doi.org/10.1016/j.ccr.2012.04.023

SOX2 expression associates with stem cell state in human ovarian carcinoma.

Autori: Bareiss, P.M. Paczulla, A. Wang, H. a ďalší

Predmety: Animals, Apoptosis, Biomarkers, Tumor/genetics, Tumor/metabolism, Blotting, Western, Cell Cycle, Cell Proliferation, Cell Transformation, Neoplastic/genetics, Neoplastic/metabolism, Neoplastic/pathology, Cystadenocarcinoma, Serous/genetics, Serous/metabolism, Serous/pathology, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Immunoenzyme Techniques, Mice, Inbred NOD, Neoplastic Stem Cells/metabolism, Neoplastic Stem Cells/pathology, Oligonucleotide Array Sequence Analysis, Ovarian Neoplasms/genetics, Ovarian Neoplasms/metabolism

Relation: Cancer Research; https://iris.unil.ch/handle/iris/52329; serval:BIB_35974FCCA707; 000324114400024

Dostupnosť: https://iris.unil.ch/handle/iris/52329
https://doi.org/10.1158/0008-5472.CAN-12-4177

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.

Autori: Vasquez, E.G. Nasreddin, N. Valbuena, G.N. a ďalší

Predmety: Animals, Colorectal Neoplasms/pathology, Homeostasis/physiology, Humans, Intestinal Mucosa/metabolism, Intestines, Mice, Neoplastic Stem Cells/pathology, Receptors, G-Protein-Coupled/metabolism, cell plasticity, colorectal cancer, colorectal neoplasia, intestinal polyps, intestinal stem cells, molecular phenotyping, stem cells

Popis súboru: application/pdf

Relation: Cell Stem Cell; https://iris.unil.ch/handle/iris/248452; serval:BIB_F6FA89020738; 000843892000007

Dostupnosť: https://iris.unil.ch/handle/iris/248452
https://doi.org/10.1016/j.stem.2022.07.008