Výsledky vyhledávání - "Navratilova, Edita"

OnabotulinumtoxinA inhibits dysregulation of descending pain modulation following mild traumatic brain injury in mice.

Autoři: Vizin, Robson C. Lillo Kopruszinski, Caroline M. Oyarzo, Janice N. a další

Zdroj: Journal of Headache & Pain; 10/16/2025, Vol. 26 Issue 1, p1-14, 14p

Témata: DATA analysis, T-test (Statistics), EARLY medical intervention, RESEARCH funding, HEADACHE, TWO-way analysis of variance, DESCRIPTIVE statistics, MICE, BOTULINUM toxin, PAIN, PAIN management, DRUG efficacy, ANIMAL experimentation, STATISTICS, ONE-way analysis of variance, BRAIN injuries, DATA analysis software

Cortical kappa opioid receptors integrate negative affect and sleep disturbance.

Autoři: Lillo Vizin, Robson C. Ito, Hisakatsu Kopruszinski, Caroline M. a další

Zdroj: Translational Psychiatry; 10/4/2024, Vol. 14 Issue 1, p1-7, 7p

Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain.

Autoři: Dogrul, Bekir Nihat Machado Kopruszinski, Caroline Dolatyari Eslami, Mahdi a další

Zdroj: PAIN; Jan2025, Vol. 166 Issue 1, p153-159, 7p

Nociceptors are functionally male or female: from mouse to monkey to man.

Autoři: Stratton, Harrison Lee, Grace Dolatyari, Mahdi a další

Zdroj: Brain: A Journal of Neurology; Dec2024, Vol. 147 Issue 12, p4280-4291, 12p

Témata: SEXUAL dimorphism, DORSAL root ganglia, PATCH-clamp techniques (Electrophysiology), SENSORY neurons, PAIN perception

A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain.

Autoři: Stratton, Harrison J. Dolatyari, Mahdi Kopruszinski, Carol a další

Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 5/20/2025, Vol. 122 Issue 20, p1-12, 34p

Témata: DORSAL root ganglia, POSTOPERATIVE pain, IMMOBILIZATION stress, GENETIC transcription, PSYCHOLOGICAL stress

Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors.

Autoři: Ji, Guangchen Presto, Peyton Kiritoshi, Takaki a další

Zdroj: Cells (2073-4409); Apr2024, Vol. 13 Issue 8, p705, 19p

Témata: OPIOID receptors, AMYGDALOID body, NEURALGIA, NEURONS, GENETIC vectors, TRANSGENIC mice, CHEMOGENETICS

Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons.

Autoři: Sato, Daisuke Narita, Michiko Hamada, Yusuke a další

Zdroj: Molecular Brain; 1/6/2022, Vol. 15 Issue 1, p1-13, 13p

Témata: NEURALGIA, DOPAMINE receptors, NUCLEUS accumbens, DOPAMINERGIC neurons, NEURONS, ANALGESIA, INTERNEURONS, SCIATIC nerve

Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.

Autoři: Ito, Hisakatsu Navratilova, Edita Vagnerova, Barbora a další

Zdroj: Brain: A Journal of Neurology; Mar2023, Vol. 146 Issue 3, p1186-1199, 14p

Témata: OPIOID receptors, SLEEP interruptions, CHRONIC pain, DYNORPHINS, RAPID eye movement sleep

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders.

Autoři: Maciuba, Stephanie Bowden, Gregory D. Stratton, Harrison J. a další

Zdroj: mAbs (1942-0862); Jan-Dec2023, Vol. 15 Issue 1, p1-13, 13p

Exploring the neurobiology of the premonitory phase of migraine preclinically – a role for hypothalamic kappa opioid receptors?

Autoři: Kopruszinski, Caroline M. Vizin, Robson Watanabe, Moe a další

Zdroj: Journal of Headache & Pain; 9/30/2022, Vol. 23 Issue 1, p1-11, 11p

Témata: MIGRAINE prevention, ANIMAL behavior, BIOLOGICAL models, NARCOTICS, STATISTICAL power analysis, NEUROBIOLOGY, ANALYSIS of variance, MIGRAINE, ANIMAL experimentation, URINATION, ONE-way analysis of variance, OPIOID receptors, WATER, REGRESSION analysis, RATS, APOMORPHINE, CELLULAR signal transduction, HYPOTHALAMUS, DESCRIPTIVE statistics, CLOZAPINE, POLYURIA, DATA analysis software, THIRST, YAWNING, ALLODYNIA, EARLY medical intervention, MICE

Female-selective mechanisms promoting migraine.

Autoři: Singh, Shagun Kopruszinski, Caroline M. Watanabe, Moe a další

Zdroj: Journal of Headache & Pain; 4/24/2024, Vol. 25 Issue 1, p1-10, 10p

Témata: NOCICEPTORS, PAIN measurement, SEX distribution, PROLACTIN, NEUROPEPTIDES, PAIN management, INDIVIDUALIZED medicine, MIGRAINE, NEUROTRANSMITTERS, CHEMICAL inhibitors

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain.

Autoři: Yakhnitsa, Vadim Ji, Guangchen Hein, Matthew a další

Zdroj: Frontiers in Pharmacology; 5/25/2022, Vol. 13, p1-16, 16p

Témata: CORTICOTROPIN releasing hormone, OPIOID receptors, AMYGDALOID body, ANIMAL disease models, NEURONS, LABORATORY rats, ELECTRIC stimulation

Unraveling the directional relationship of sleep and migraine-like pain.

Autoři: Vizin, Robson C Lillo Kopruszinski, Caroline M Redman, Paula M a další

Zdroj: Brain Communications; 2024, Vol. 6 Issue 2, p1-16, 16p

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex.

Autoři: Navratilova, Edita Chaoling Qu Guangchen Ji a další

Zdroj: Anesthesiology; Feb2024, Vol. 140 Issue 2, p272-283, 12p

Preclinical Assessment of the Analgesic Pharmacology of NKTR-181 in Rodents.

Autoři: Kopruszinski, Caroline M. Swiokla, Juliana Lee, Yeon Sun a další

Zdroj: Cellular & Molecular Neurobiology; Jul2021, Vol. 41 Issue 5, p949-960, 12p

Témata: OPIOID analgesics, PHARMACOLOGY, RODENTS, STIMULUS intensity, RATS, WATER temperature

The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females.

Autoři: Chen, Yanxia Moutal, Aubin Navratilova, Edita a další

Zdroj: Science Translational Medicine; 2/5/2020, Vol. 12 Issue 529, p1-13, 13p

Témata: HYPERALGESIA, PROLACTIN, FEMALES, DOPAMINE agonists, GENE targeting, SENSORY neurons, GENE therapy

Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming.

Autoři: Kopruszinski, Caroline M. Watanabe, Moe Martinez, Ashley L. a další

Zdroj: PAIN; Jun2023, Vol. 164 Issue 6, pe263-e273, 11p

Kappa opioid signaling in the central nucleus of the amygdala promotes disinhibition and aversiveness of chronic neuropathic pain.

Autoři: Navratilova, Edita Ji, Guangchen Phelps, Caroline a další

Zdroj: PAIN; Apr2019, Vol. 160 Issue 4, p824-832, 9p

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.

Autoři: Watanabe, Moe Kopruszinski, Caroline M Moutal, Aubin a další

Zdroj: Brain: A Journal of Neurology; Aug2022, Vol. 145 Issue 8, p2894-2909, 16p

Témata: PAIN, NEURONS, MIGRAINE, CELL receptors, NOCICEPTORS, PROLACTIN, HYPOTHALAMUS, RESEARCH funding, HYPERALGESIA, ANIMALS, MICE

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex

Autoři: Navratilova, Edita Qu, Chaoling Ji, Guangchen a další

Zdroj: Anesthesiology ; volume 140, issue 2, page 272-283 ; ISSN 0003-3022

Dostupnost: https://doi.org/10.1097/aln.0000000000004773
https://pubs.asahq.org/anesthesiology/article-pdf/140/2/272/699640/20240200.0-00018.pdf
https://journals.lww.com/10.1097/ALN.0000000000004773