Suchergebnisse - "Nanoparticles administration & dosage"

Functionalized Nanoparticles: A New Concept for Actively Repairing Intracellular Damage in Complex Diseases

Autoren: Nawafleh, Renad

Schlagwörter: Nanomedicine, Magnetic Iron Oxide Nanoparticles/classification, Magnetic Iron Oxide Nanoparticles/administration & dosage, Cardiovascular Diseases, Nanoparticles, Multifunctional Nanoparticles, Intracellular Space/genetics, Cancer

A gold nanoparticle/peptide vaccine designed to induce SARS-CoV-2-specific CD8 T cells: a double-blind, randomized, phase 1 study in Switzerland

Autoren: Miauton, A. Hajjami, H.M. Warpelin-Decrausaz, L. et al.

Quelle: BMC infectious diseases, vol. 25, no. 1, pp. 472

Schlagwörter: Humans, Double-Blind Method, COVID-19 Vaccines/immunology, COVID-19 Vaccines/administration & dosage, COVID-19 Vaccines/adverse effects, Adult, CD8-Positive T-Lymphocytes/immunology, Male, Female, SARS-CoV-2/immunology, COVID-19/prevention & control, COVID-19/immunology, Middle Aged, Switzerland, Gold/chemistry, Metal Nanoparticles/chemistry, Metal Nanoparticles/administration & dosage, Vaccines, Subunit/immunology, Vaccines, Subunit/administration & dosage, Young Adult, Antibodies, Viral/blood, Protein Subunit Vaccines, COVID-19, Cellular, Immunity, Nanoparticle, SARS-CoV-2, Vaccine

Dateibeschreibung: application/pdf

Zugangs-URL: https://serval.unil.ch/notice/serval:BIB_F157802054D9
https://serval.unil.ch/resource/serval:BIB_F157802054D9.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F157802054D97

Beyond the EPR effect:Intravital microscopy analysis of nanoparticle drug delivery to tumors

Autoren: Belyaev, Iaroslav B. Griaznova, Olga Yu Yaremenko, Alexey V. et al.

Quelle: Belyaev, I B, Griaznova, O Y, Yaremenko, A V, Deyev, S M & Zelepukin, I V 2025, 'Beyond the EPR effect : Intravital microscopy analysis of nanoparticle drug delivery to tumors', Advanced Drug Delivery Reviews, vol. 219, 115550. https://doi.org/10.1016/j.addr.2025.115550

Schlagwörter: Endothelial extravasation, EPR alternatives, EPR effect, Intravital microscopy, Nanoparticle delivery, Nanoparticles/administration & dosage, Antineoplastic Agents/administration & dosage, Humans, Neoplasms/drug therapy, Drug Delivery Systems, Animals, Nanoparticle Drug Delivery System

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/40021012; info:eu-repo/semantics/altIdentifier/pissn/0169-409X; info:eu-repo/semantics/altIdentifier/eissn/1872-8294

Verfügbarkeit: https://research.tue.nl/en/publications/48e21afa-7042-4866-bc6d-d22b322298c6
https://doi.org/10.1016/j.addr.2025.115550
https://pure.tue.nl/ws/files/365656894/1-s2.0-S0169409X25000353-main.pdf
https://www.scopus.com/pages/publications/85219313532

MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

Autoren: Peters, Linsey Rakateli, Leonida Huchzermeier, Rosanna et al.

Quelle: Peters, L, Rakateli, L, Huchzermeier, R, Bonnin-Marquez, A, Maas, S L, Lin, C, Jans, A, Geng, Y, Gorter, A, Gijbels, M, Rensen, S, Olinga, P, Hendrikx, T, Krawczyk, M, Brisbois, M, Jankowski, J, Bidzhekov, K, Weber, C, Biessen, E A L, Shiri-Sverdlov, R, Houben, T, Doering, Y, Bartneck, M & van der Vorst, E 2025, 'MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles', Elife, vol. 13. https://doi.org/10.7554/eLife.97165

Schlagwörter: hepatic inflammation, human, immunology, inflammation, lipid nanoparticles, metabolic dysfunction-associated steatohepatitis, microRNAs, mouse, Animals, MicroRNAs/genetics metabolism, Nanoparticles/administration & dosage chemistry, Mice, Humans, Liver/pathology metabolism, Lipid Metabolism, Knockout, Fatty Liver/prevention & control genetics, Male, Apolipoproteins E/genetics, Disease Models, Animal, Liposomes

Verfügbarkeit: https://cris.maastrichtuniversity.nl/en/publications/ad7a196d-5e6c-46c9-a15c-baa7aadc1b7e
https://doi.org/10.7554/eLife.97165

MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

Autoren: Leonida Rakateli Linsey Peters Rosanna Huchzermeier et al.

Quelle: eLife
eLife, Vol 13 (2025)

Schlagwörter: Male, QH301-705.5, Knockout, Science, Fatty Liver/prevention & control genetics, lipid nanoparticles, immunology, Mice, Immunology and Inflammation, Apolipoproteins E, Liver/pathology metabolism, Nanoparticles/administration & dosage chemistry, Animals, Humans, human, Biology (General), mouse, Mice, Knockout, hepatic inflammation, Animal, MicroRNAs/genetics metabolism, Lipid Metabolism, microRNAs, Fatty Liver, MicroRNAs, Disease Models, Animal, metabolic dysfunction-associated steatohepatitis, Liver, inflammation, Disease Models, Liposomes, Medicine, Nanoparticles, Apolipoproteins E/genetics

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40261813
https://doaj.org/article/fc05e0d77f5f47429f535551ad4b70b7
https://cris.maastrichtuniversity.nl/en/publications/ad7a196d-5e6c-46c9-a15c-baa7aadc1b7e
https://doi.org/10.7554/eLife.97165
https://epub.ub.uni-muenchen.de/126056/

In vitro evaluation of novel (nanoparticle) oral delivery systems allow selection of gut immunomodulatory formulations

Autoren: Ahmed Attaya Kimberly Veenstra Michael D. Welsh et al.

Quelle: Fish & Shellfish Immunology. 113:125-138

Schlagwörter: Oral, 0301 basic medicine, Immunologic/administration & dosage, Administration, Oral, Macrophages/immunology, Aeromonas salmonicida, Adaptive Immunity, Monocytes, Cell Line, Aeromonas salmonicida/immunology, Fish Diseases, 03 medical and health sciences, Drug Delivery Systems, Adjuvants, Immunologic, Fish Diseases/immunology, Oncorhynchus mykiss/immunology, Bacterial/immunology, Innate, Animals, Adjuvants, Antigens, Gram-Negative Bacterial Infections/immunology, Antigens, Bacterial, 0303 health sciences, Macrophages, Vaccination, Immunity, Monocytes/immunology, Vaccination/instrumentation, Drug Delivery Systems/instrumentation, Nanoparticles/administration & dosage, Immunity, Innate, 3. Good health, Oncorhynchus mykiss, Administration, Bacterial Vaccines, Bacterial Vaccines/administration & dosage, Nanoparticles, Gram-Negative Bacterial Infections

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/33746060
https://pubmed.ncbi.nlm.nih.gov/33746060/
https://europepmc.org/article/MED/33746060
https://www.sciencedirect.com/science/article/pii/S1050464821000668
http://www.ncbi.nlm.nih.gov/pubmed/33746060

Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours

Autoren: David S. Hong Yoon-Koo Kang Mitesh Borad et al.

Weitere Verfasser: David S. Hong Yoon-Koo Kang Mitesh Borad et al.

Quelle: Br J Cancer

Schlagwörter: Adult, Male, 0301 basic medicine, Liposomes / adverse effects, Maximum Tolerated Dose, Antineoplastic Agents, Article, 03 medical and health sciences, MicroRNAs / pharmacokinetics, Neoplasms, 80 and over, Humans, Neoplasms / drug therapy, Antineoplastic Agents / adverse effects, Aged, Aged, 80 and over, 0303 health sciences, Nanoparticles / adverse effects, Liposomes / pharmacokinetics, Nanoparticles / administration & dosage, Middle Aged, MicroRNAs / administration & dosage, 3. Good health, MicroRNAs, Antineoplastic Agents / administration & dosage, Liposomes, MicroRNAs / adverse effects, Nanoparticles, Female, Antineoplastic Agents / pharmacokinetics

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/32238921
https://europepmc.org/article/PMC/PMC7251107
http://www-nature-com-443.webvpn.bjmu.tsg211.com/articles/s41416-020-0802-1
https://www.nature.com/articles/s41416-020-0802-1.pdf
https://utsouthwestern.pure.elsevier.com/en/publications/phase-1-study-of-mrx34-a-liposomal-mir-34a-mimic-in-patients-with
https://pubmed.ncbi.nlm.nih.gov/32238921/
https://www.nature.com/articles/s41416-020-0802-1

Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV + Cancers.

Autoren: Galliverti, G. Wullschleger, S. Tichet, M. et al.

Schlagwörter: Animals, Antineoplastic Agents, Immunological/pharmacology, CD8-Positive T-Lymphocytes/immunology, CTLA-4 Antigen/antagonists & inhibitors, Disease Models, Animal, Drug Synergism, Female, Humans, Immunosuppression, Immunotherapy/methods, Mice, Myeloid Cells/drug effects, Myeloid Cells/immunology, Nanoparticles/administration & dosage, Papillomaviridae/immunology, Papillomavirus E7 Proteins/immunology, Papillomavirus E7 Proteins/metabolism, Papillomavirus Infections/drug therapy, Papillomavirus Infections/immunology, Papillomavirus Infections/virology, Papillomavirus Vaccines/administration & dosage, Papillomavirus Vaccines/immunology, Programmed Cell Death 1 Receptor/antagonists & inhibitors, Tumor Microenvironment, Uterine Cervical Neoplasms/drug therapy, Uterine Cervical Neoplasms/immunology, Uterine Cervical Neoplasms/pathology, Uterine Cervical Neoplasms/virology

Relation: Cancer Immunology Research; https://iris.unil.ch/handle/iris/92964; serval:BIB_04D464D7C6BB; 000505667700013

Verfügbarkeit: https://iris.unil.ch/handle/iris/92964
https://doi.org/10.1158/2326-6066.CIR-19-0315

Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice.

Autoren: Ballester, M. Jeanbart, L. de Titta, A. et al.

Schlagwörter: Adjuvants, Immunologic/administration & dosage, Immunologic/therapeutic use, Administration, Inhalation, Animals, Cytokines/biosynthesis, Cytokines/drug effects, Dendritic Cells/drug effects, Dendritic Cells/immunology, Hypersensitivity/drug therapy, Hypersensitivity/immunology, Mice, Nanoparticles/administration & dosage, Nanoparticles/therapeutic use, Oligodeoxyribonucleotides/administration & dosage, Oligodeoxyribonucleotides/therapeutic use, Pyroglyphidae/immunology, T-Lymphocytes, Helper-Inducer/drug effects, Helper-Inducer/immunology

Dateibeschreibung: application/pdf

Relation: Scientific Reports; https://iris.unil.ch/handle/iris/88361; serval:BIB_0E381269A57B; 000361463200001

Verfügbarkeit: https://iris.unil.ch/handle/iris/88361
https://doi.org/10.1038/srep14274

Off-resonance angiography: a new method to depict vessels--phantom and rabbit studies.

Autoren: Korosoglou, G. Shah, S. Vonken, E.J. et al.

Schlagwörter: Animals, Contrast Media/administration & dosage, Ferrosoferric Oxide/administration & dosage, Magnetic Resonance Angiography/methods, Nanoparticles/administration & dosage, Phantoms, Imaging, Rabbits, Regression Analysis

Relation: Radiology; 1527-1315[electronic], 0033-8419[linking]; https://iris.unil.ch/handle/iris/218974; serval:BIB_74E4389DFA9F; 000260215400015

Verfügbarkeit: https://iris.unil.ch/handle/iris/218974
https://doi.org/10.1148/radiol.2491071706

Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells.

Autoren: Barar, J. Kafil, V. Majd, M.H. et al.

Schlagwörter: Antineoplastic Agents/administration & dosage, Antineoplastic Agents/chemistry, Apoptosis/drug effects, Apoptosis/genetics, Cell Line, Tumor/drug effects, Cell Survival/drug effects, DNA Fragmentation/drug effects, Folate Receptors, GPI-Anchored/metabolism, Folic Acid/administration & dosage, Folic Acid/chemistry, Gene Expression Regulation, Neoplastic/drug effects, Humans, MCF-7 Cells/drug effects, Magnetite Nanoparticles/administration & dosage, Magnetite Nanoparticles/chemistry, Microscopy, Atomic Force, Mitoxantrone/administration & dosage, Mitoxantrone/chemistry, Molecular Targeted Therapy/methods, Particle Size, Polyethylene Glycols/chemistry

Dateibeschreibung: application/pdf

Relation: Journal of nanobiotechnology; https://iris.unil.ch/handle/iris/155605; serval:BIB_D3C3F085EE13; 000352262100001

Verfügbarkeit: https://iris.unil.ch/handle/iris/155605
https://doi.org/10.1186/s12951-015-0083-7

Current Strategies for Brain Drug Delivery

Autoren: Dong, Xiaowei

Quelle: Theranostics

Schlagwörter: actively targeted delivery, aging, disease conditions, permeable blood-brain barrier, ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism, Animals, Biological Transport, Blood-Brain Barrier / drug effects, Blood-Brain Barrier / metabolism, Brain / drug effects, Brain / metabolism, Diabetes Mellitus / drug therapy, Diabetes Mellitus / metabolism, Diabetes Mellitus / pathology, Drug Carriers / chemistry, Drug Carriers / classification, Drug Carriers / pharmacokinetics, Exosomes / metabolism, Genetic Vectors / metabolism, Genetic Vectors / pharmacokinetics, Glucose Transporter Type 1 / metabolism, Humans, Nanoparticles / administration & dosage, Nanoparticles / metabolism, Neurodegenerative Diseases / drug therapy, Neurodegenerative Diseases / metabolism, Neurodegenerative Diseases / pathology, Prescription Drugs / pharmacokinetics

Dateibeschreibung: application/pdf

Relation: https://doi.org/10.7150/thno.21254; https://hdl.handle.net/20.500.12503/31743

Verfügbarkeit: https://hdl.handle.net/20.500.12503/31743

Nanotechnology-Ocular Devices for Glaucoma Treatment: A Literature Review

Autoren: Cardigos, J Ferreira, Q Crisóstomo, S et al.

Quelle: Current Eye Research. 44:111-117

Schlagwörter: Nanotechnology / instrumentation, HSAC OFT, Glaucoma, Nanoparticles / administration & dosage, Antihypertensive Agents / administration & dosage, 3. Good health, 03 medical and health sciences, Drug Delivery Systems, 0302 clinical medicine, Glaucoma / drug therapy, Humans, Nanoparticles, Nanotechnology, Antihypertensive Agents

Zugangs-URL: http://repositorio.chlc.min-saude.pt/bitstream/10400.17/3858/1/Curr%20Eye%20Res%202019%20111.pdf
https://pubmed.ncbi.nlm.nih.gov/30309248
https://www.ncbi.nlm.nih.gov/pubmed/30309248
https://www.tandfonline.com/doi/full/10.1080/02713683.2018.1536218
https://pubmed.ncbi.nlm.nih.gov/30309248/
https://novaresearch.unl.pt/en/publications/nanotechnology-ocular-devices-for-glaucoma-treatment-a-literature
https://repositorio.chlc.min-saude.pt/handle/10400.17/3858?locale=en
http://hdl.handle.net/10400.17/3858

MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells

Autoren: Annalisa Ferino Giulia Miglietta Raffaella Picco et al.

Quelle: RNA Biol
Ferino, A, Miglietta, G, Picco, R, Vogel, S, Wengel, J & Xodo, L E 2018, ' MicroRNA therapeutics : design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells ', RNA Biology, vol. 15, no. 10, pp. 1273-1285 . https://doi.org/10.1080/15476286.2018.1526536

Schlagwörter: 0301 basic medicine, AGO2, KRAS, miR-216b, PDAC cells, POPC liposome, Molecular Biology, Cell Biology, Pancreatic Ductal/genetics, Carcinoma, Pancreatic Ductal/genetics, Lipids/chemistry, Cell Line, Proto-Oncogene Proteins p21(ras), Cell Proliferation/genetics, 03 medical and health sciences, MicroRNAs/chemistry, Cell Line, Tumor, Argonaute Proteins/genetics, Humans, 3' Untranslated Regions, Pancreas, Cell Proliferation, Pancreas/metabolism, 0303 health sciences, Tumor, Carcinoma, Neoplastic/genetics, Nanoparticles/administration & dosage, Lipids, 3. Good health, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Neoplastic/genetics, MicroRNAs, Gene Expression Regulation, 3' Untranslated Regions/genetics, Proto-Oncogene Proteins p21(ras)/antagonists & inhibitors, Argonaute Proteins, Liposomes, Nanoparticles, Liposomes/chemistry, Research Paper, Carcinoma, Pancreatic Ductal

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.tandfonline.com/doi/pdf/10.1080/15476286.2018.1526536?needAccess=true
https://pubmed.ncbi.nlm.nih.gov/30306823
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284578/
https://www.tandfonline.com/doi/full/10.1080/15476286.2018.1526536
https://pubmed.ncbi.nlm.nih.gov/30306823/
https://portal.findresearcher.sdu.dk/en/publications/microrna-therapeutics-design-of-single-stranded-mir-216b-mimics-t
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284578/
http://findresearcher.sdu.dk/portal/da/publications/microrna-therapeutics(0511dac2-b292-4c3f-a7b2-c3433ca43470).html
https://findresearcher.sdu.dk:8443/ws/files/144402099/MicroRNA_therapeutics_design_of_single_stranded_miR_216b_mimics_to_target_KRAS_in_pancreatic_cancer_cells.pdf
https://portal.findresearcher.sdu.dk/da/publications/0511dac2-b292-4c3f-a7b2-c3433ca43470
https://doi.org/10.1080/15476286.2018.1526536
https://hdl.handle.net/11390/1140280
https://doi.org/10.1080/15476286.2018.1526536
https://hdl.handle.net/11585/968927
https://doi.org/10.1080/15476286.2018.1526536

Bactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines

Autoren: Katarzyna Niemirowicz-Laskowska Katarzyna Głuszek Ewelina Piktel et al.

Quelle: Int J Nanomedicine
International Journal of Nanomedicine, Vol Volume 13, Pp 3411-3424 (2018)

Schlagwörter: 0301 basic medicine, magnetic nanoparticles, Medicine (General), Dihydropyridines, Anti-infective agents - chemistry, Drug Evaluation, Preclinical, Microbial Sensitivity Tests, Dihydropyridines - chemistry, Microbial sensitivity tests, Fungi - drug effects, 03 medical and health sciences, R5-920, Anti-Infective Agents, 1,4-dihydropyridine, International Journal of Nanomedicine, Humans, Immunologic Factors, Magnetite Nanoparticles, Immunologic factors - chemistry, Original Research, 0303 health sciences, Bacteria, Anti-bacterial agents - chemistry, preclinical - methods, Fungi, Immunologic factors - pharmacology, immunomodulatory properties, Drug evaluation, Fungi - isolation & purification, Bacteria - isolation & purification, Anti-bacterial agents - pharmacology, Anti-Bacterial Agents, 3. Good health, antibacterial, Bacteria - drug effects, Magnetite nanoparticles - administration & dosage, Anti-infective agents - pharmacology, Magnetite nanoparticles - chemistry, 4-dihydropyridine, antifungal

Dateibeschreibung: text/html; application/pdf

Zugangs-URL: https://www.dovepress.com/getfile.php?fileID=42555
https://pubmed.ncbi.nlm.nih.gov/29928120
https://doaj.org/article/e32e7d4c62804fc99358142898c368ef
https://www.dovepress.com/bactericidal-and-immunomodulatory-properties-of-magnetic-nanoparticles-peer-reviewed-article-IJN
https://www.dovepress.com/bactericidal-and-immunomodulatory-properties-of-magnetic-nanoparticles-peer-reviewed-fulltext-article-IJN
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001743
http://europepmc.org/articles/PMC6001743
https://www.dovepress.com/getfile.php?fileID=42555
https://doi.org/10.2147/IJN.S157564

Silica nanoparticle-induced oxidative stress and mitochondrial damage is followed by activation of intrinsic apoptosis pathway in glioblastoma cells

Autoren: Magdalena Kusaczuk Rafał Krętowski Monika Naumowicz et al.

Quelle: Int J Nanomedicine
International Journal of Nanomedicine, Vol Volume 13, Pp 2279-2294 (2018)

Schlagwörter: 0301 basic medicine, Medicine (General), mitochondrial damage, Mitochondria - metabolism, Glioblastoma - drug therapy, Brain neoplasms - drug therapy, Antineoplastic agents - pharmacology, Apoptosis, silica nanoparticles, International Journal of Nanomedicine, Endoplasmic Reticulum Chaperone BiP, Original Research, Gene expression regulation, 0303 health sciences, Brain Neoplasms, apoptosis, Endoplasmic Reticulum Stress, Silicon Dioxide, Silicon dioxide - pharmacology, Caspase 9, Mitochondria, 3. Good health, Gene Expression Regulation, Neoplastic, Glioblastoma - pathology, Endoplasmic reticulum stress - drug effects, ER stress, tumor, Apoptosis - drug effects, Antineoplastic Agents, Mitochondria - drug effects, Nanoparticles - administration & dosage, Brain neoplasms - pathology, 03 medical and health sciences, R5-920, Cell Line, Tumor, Animals, Humans, Silicon dioxide - administration & dosage, Transcription factor CHOP - metabolism, Endoplasmic reticulum stress - genetics, neoplastic, Antineoplastic agents - administration & dosage, Oxidative stress - drug effects, Nanoparticles - chemistry, Oxidative Stress, nanotoxicity, Nanoparticles, Brain neoplasms - metabolism, Cell line, Glioblastoma - metabolism, Glioblastoma, Transcription Factor CHOP

Dateibeschreibung: text/html

Zugangs-URL: https://www.dovepress.com/getfile.php?fileID=41501
https://pubmed.ncbi.nlm.nih.gov/29695906
https://doaj.org/article/a0100ab4c3e04149953f5d09ddee99b6
https://www.dovepress.com/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage--peer-reviewed-article-IJN
https://www.dovepress.com/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage--peer-reviewed-fulltext-article-IJN
https://www.dovepress.com/getfile.php?fileID=41501
https://doi.org/10.2147/IJN.S158393
https://europepmc.org/article/MED/29695906
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905826
https://paperity.org/p/107567171/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage-is-followed-by
https://www.dovepress.com/silica-nanoparticle-induced-oxidative-stress-and-mitochondrial-damage--peer-reviewed-fulltext-article-IJN
https://doi.org/10.2147/IJN.S158393

Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis

Autoren: Maudens, Pierre Marc Xavier Seemayer, Christian Alexander Pfefferlé, François et al.

Quelle: Journal of Controlled Release, Vol. 276 (2018) pp. 102-112

Schlagwörter: Male, 0301 basic medicine, Benzamides/administration & dosage/chemistry, Pyridones, p38 Mitogen-Activated Protein Kinases, 03 medical and health sciences, Osteoarthritis, Osteoarthritis/drug therapy, Animals, Humans, Protein Kinase Inhibitors/administration & dosage/chemistry, Protein Kinase Inhibitors, ddc:615, 0303 health sciences, Anti-Inflammatory Agents, Non-Steroidal, Pyridones/administration & dosage/chemistry, Mice, Inbred C57BL, Disease Models, Animal, Drug Liberation, Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/chemistry, Delayed-Action Preparations/administration & dosage/chemistry, Nanoparticles/administration & dosage/chemistry, Delayed-Action Preparations, Benzamides, Nanoparticles, p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors

Dateibeschreibung: application/pdf

Zugangs-URL: https://archive-ouverte.unige.ch/unige:141549/ATTACHMENT01
https://pubmed.ncbi.nlm.nih.gov/29524442
https://www.ncbi.nlm.nih.gov/pubmed/29524442
https://www.sciencedirect.com/science/article/pii/S0168365918301299
https://archive-ouverte.unige.ch/unige:141549
http://europepmc.org/abstract/MED/29524442
https://pubmed.ncbi.nlm.nih.gov/29524442/
https://archive-ouverte.unige.ch/unige:141549/ATTACHMENT01
https://archive-ouverte.unige.ch/unige:141549
https://archive-ouverte.unige.ch/unige:141549
https://doi.org/10.1016/j.jconrel.2018.03.007

Si Isotope-Enriched Silicon Nanoparticles for an Efficient Hyperpolarized Magnetic Resonance Imaging Probe

Weitere Verfasser: Jiwon Kim Donghyuk Jo Seung-Hyun Yang et al.

Schlagwörter: Animals, Biomimetic Materials / administration & dosage, Biomimetic Materials / chemical synthesis, Biomimetic Materials / chemistry, Contrast Media / administration & dosage, Contrast Media / chemical synthesis, Contrast Media / chemistry, Isotopes, Magnetic Resonance Imaging, Male, Materials Testing, Mice, Inbred BALB C, Nude, Nanoparticles / administration & dosage, Nanoparticles / chemistry, Particle Size, Phantom Limb / diagnostic imaging, Porosity, Silicon / administration & dosage, Silicon / chemistry, hyperpolarization, isotope enrichment, magnetic resonance imaging, nanoimaging, silicon nanoparticles

Relation: ACS APPLIED MATERIALS & INTERFACES; J00004; https://ir.ymlib.yonsei.ac.kr/handle/22282913/188146; T202125618

Verfügbarkeit: https://ir.ymlib.yonsei.ac.kr/handle/22282913/188146
https://doi.org/10.1021/acsami.1c16617
https://pubs.acs.org/doi/10.1021/acsami.1c16617

Thermo-responsive magnetic Fe 3 O 4 @P(MEO 2 MA X -OEGMA 100-X ) NPs and their applications as drug delivery systems

Autoren: Joumana Toufaily Raphaël Schneider Eric Gaffet et al.

Quelle: International Journal of Pharmaceutics. 532:738-747

Schlagwörter: Cell Survival, Antineoplastic Agents chemistry, Antineoplastic Agents, 02 engineering and technology, Polyethylene Glycols administration & dosage, 01 natural sciences, Polyethylene Glycols, Magnetite Nanoparticles chemistry, Drug Delivery Systems, Polyethylene Glycols chemistry, Polymethacrylic Acids, Polymethacrylic Acids chemistry, Antineoplastic Agents administration & dosage, Humans, Magnetite Nanoparticles administration & dosage, Magnetite Nanoparticles, Doxorubicin administration & dosage, Doxorubicin chemistry, Polymethacrylic Acids administration & dosage, Temperature, 0104 chemical sciences, 3. Good health, Drug Liberation, Doxorubicin, Cell Survival drug effects, 0210 nano-technology, HT29 Cells

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/28893585
https://cris.maastrichtuniversity.nl/en/publications/67e1f223-ab10-405b-b501-3b5b17ffac79
https://doi.org/10.1016/j.ijpharm.2017.09.019
https://europepmc.org/article/MED/28893585
https://www.sciencedirect.com/science/article/pii/S0378517317308748
https://www.ncbi.nlm.nih.gov/pubmed/28893585
https://hal.archives-ouvertes.fr/hal-01650405

Use of magnetic nanoparticles as a drug delivery system to improve chlorhexidine antimicrobial activity

Autoren: Katarzyna Niemirowicz Jan Ryszard Dąbrowski Mateusz Cieśluk et al.

Quelle: Int J Nanomedicine
International Journal of Nanomedicine, Vol Volume 12, Pp 7833-7846 (2017)

Schlagwörter: 0301 basic medicine, magnetic nanoparticles, Medicine (General), antimicrobial properties, Plankton - microbiology, Microbial Sensitivity Tests, Microbial sensitivity tests, Gram-Positive Bacteria, Gram-negative bacteria - drug effects, Cell Line, 03 medical and health sciences, R5-920, Drug Delivery Systems, Anti-Infective Agents, International Journal of Nanomedicine, Gram-Negative Bacteria, Interleukin-8 - metabolism, Gram-positive bacteria - drug effects, Humans, anti-biofilm, Magnetite Nanoparticles, Chlorhexidine - administration & dosage, Original Research, Osteoblasts - drug effects, 0303 health sciences, Osteoblasts, Chlorhexidine - pharmacology, chlorhexidine, Chlorhexidine, Interleukin-8, Plankton, 16. Peace & justice, Drug delivery systems - methods, Osteoblasts - metabolism, 3. Good health, Oxidative stress - drug effects, Biofilms - drug effects, Oxidative Stress, Anti-infective agents - administration & dosage, Biofilms, Magnetite nanoparticles - administration & dosage, Anti-infective agents - pharmacology, Magnetite nanoparticles - chemistry, Cell line

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https://pubmed.ncbi.nlm.nih.gov/29123396
https://doaj.org/article/70139e271e2f4264b4c77848d4274809
https://www.dovepress.com/use-of-magnetic-nanoparticles-as-a-drug-delivery-system-to-improve-chl-peer-reviewed-article-IJN
https://europepmc.org/articles/PMC5661836
https://www.ncbi.nlm.nih.gov/pubmed/29123396
https://www.dovepress.com/getfile.php?fileID=39028
https://pubmed.ncbi.nlm.nih.gov/29123396/
https://www.dovepress.com/use-of-magnetic-nanoparticles-as-a-drug-delivery-system-to-improve-chl-peer-reviewed-fulltext-article-IJN