Suchergebnisse - "NLRP3 inflammasome"

NLRP3 inflammasome: a key player in neonatal brain injury

Autoren: Cagla Kiser Ilkcan Ercan Defne Engur et al.

Quelle: Clin Exp Pediatr
Clinical and Experimental Pediatrics, Vol 68, Iss 7, Pp 475-485 (2025)

Schlagwörter: neonatal, nlrp3 inflammasome, hypoxia, Review Article, brain injury, Pediatrics, RJ1-570

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40211861
https://doaj.org/article/1c3a3831508e40b283ee6b7e59230aab

Redox modulation by a synthetic thiol compound reduces LPS-induced pro-inflammatory cytokine expression in macrophages via AP-1/NLRP3 axis and influences the crosstalk with endothelial cells

Autoren: Sofia Masini Michela Bruschi Michele Menotta et al.

Quelle: Free Radical Research. 59:487-505

Schlagwörter: NLRP3 inflammasome, ROS, endothelial cells, macrophages, thiol compound

Dateibeschreibung: application/pdf

Danshensu Ethyl Ester Alleviates LPS-Induced Acute Lung Injury by Targeting the NLRP3 Inflammasome

Autoren: Wensi Ding Sen Xu Shuyang Xie et al.

Quelle: J Inflamm Res
Journal of Inflammation Research, Vol Volume 18, Iss Issue 1, Pp 8767-8785 (2025)

Schlagwörter: inflammation, Pathology, neutrophil, RB1-214, acute lung injury (ALI), danshensu ethyl ester (DEE), Therapeutics. Pharmacology, RM1-950, lipopolysaccharide (LPS), NLRP3 inflammasome, Original Research

Zugangs-URL: https://doaj.org/article/c6584f4acb3349b99dd2ef61a927ba38

Targeting the NLRP3-ROS Axis: Disrupting the Oxidative-Inflammatory Vicious Cycle in Intracerebral Hemorrhage

Autoren: Liang Cao Wenjun Pi Yi Zhang et al.

Quelle: J Inflamm Res
Journal of Inflammation Research, Vol Volume 18, Iss Issue 1, Pp 9849-9870 (2025)

Schlagwörter: Neuroinflammation, Oxidative stress, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950, Review, Intracerebral hemorrhage, Brain injury, NLRP3 inflammasome

Zugangs-URL: https://doaj.org/article/4d4029641f8242f6b1dbe1b018bba8f0

3,4-methylenedioxymethamphetamine induces reactive oxygen species-mediated autophagy and thioredoxin-interactive protein/nucleotide-binding domain, leucine-rich containing family, pyrin domain-containing-3 inflammasome activation in dental pulp stem cells

Autoren: Shih-Yu Lee Shang-Wen Chiu I-Hsun Li et al.

Quelle: J Dent Sci
Journal of Dental Sciences, Vol 20, Iss 3, Pp 1782-1791 (2025)

Schlagwörter: 3,4-methylenedioxymethamphetamine (MDMA), Oxidative stress, Dentistry, Dental pulp stem cells (DPSCs), Nucleotide-binding domain, leucine-rich containing family, pyrin domain-containing-3 (NLRP3) inflammasome, Autophagy, RK1-715, Original Article

Zugangs-URL: https://doaj.org/article/c8ee362a0062471a88e0f551a0ba526f

GDF11 protects against mitochondrial-dysfunction-dependent NLRP3 inflammasome activation to attenuate osteoarthritis

Autoren: Pengfei Zhang Haoxin Zhai Shuai Zhang et al.

Quelle: J Adv Res
Journal of Advanced Research, Vol 73, Iss, Pp 501-515 (2025)

Schlagwörter: Medicine (General), Q1-390, R5-920, Science (General), TNF-α, GDF11, Osteoarthritis, Original Manuscript, NLRP3 inflammasome

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39103049
https://doaj.org/article/60609fe7d8cf4e1e89abd83cb1039847

Antcin-H, a natural triterpene derived from Antrodia cinnamomea, ameliorates dextran sulfate sodium-induced colitis in mice by inhibiting the NLRP3 inflammasome

Autoren: Wei-Ting Wong Lan-Hui Li Hsiao-Wen Chiu et al.

Quelle: J Tradit Complement Med
Journal of Traditional and Complementary Medicine, Vol 15, Iss 4, Pp 343-355 (2025)

Schlagwörter: Antrodia cinnamomea, Antcin-H, Medicine, Inflammatory bowel disease, NLRP3 inflammasome, Article

Zugangs-URL: https://doaj.org/article/0beff690a8db4842beb9973c2e017caa

Osteoarthritis: modern aspects of pathogenesis, focus on low-intensity inflammation

Autoren: I. S. Svintsitskaya D. S. Aganov K. V. Raimuev et al.

Quelle: Современная ревматология, Vol 19, Iss 2, Pp 119-126 (2025)

Schlagwörter: osteoarthritis, nlrp3 inflammasome, osteoarthritis phenotypes, inhibitors of nlrp3 inflammasome, Medicine, interleukin 1β, diacerein (artrodarin ®)

Zugangs-URL: https://doaj.org/article/8ebd127adab344319a594844815c580b

NLRP3 Inflammasome Inhibition by the Novel Bispecific Antibody InflamAb Attenuates Atherosclerosis in Apolipoprotein E–Deficient Mice

Autoren: Delfos, L. Depuydt, M.A.C. Chemaly, M. et al.

Quelle: JACC Basic Transl Sci

Schlagwörter: Bispecific, Interleukin-1 receptor type 1, Atherosclerosis, Interleukin-1b, Antibody, NLRP3 inflammasome, Original Research - Preclinical

Dateibeschreibung: application/pdf

Zugangs-URL: https://hdl.handle.net/1887/4212171

Probiotic Bifico Ameliorates Depression- and Anxiety-Like Behaviors Induced by Estrogen Deficiency via NLRP3 Inflammasome Inhibition

Autoren: Xia Yu Xiurong Yu Yang Yang et al.

Quelle: J Inflamm Res
Journal of Inflammation Research, Vol Volume 18, Iss Issue 1, Pp 8153-8171 (2025)

Schlagwörter: hippocampus, depression, estrogen, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950, microbiota-gut-brain axis, NLRP3 inflammasome, Original Research

Zugangs-URL: https://doaj.org/article/454b4803eeea415b84e780981c5ef2bf

NLRP3 Mediates NOXs-Induced Iron Overload and Inflammation but Not Oxidative Damage in Colons of DSS-Treated Mice

Autoren: Linna Yu Meng Wang Yunjiao Zhou et al.

Quelle: J Inflamm Res
Journal of Inflammation Research, Vol Volume 18, Pp 4695-4708 (2025)

Schlagwörter: nadph oxidases, nlrp3 inflammasome, inflammation, Pathology, ros, RB1-214, Therapeutics. Pharmacology, RM1-950, iron overload, ulcerative colitis, Original Research

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40201574
https://doaj.org/article/6f4c22c6c22f4f0e8a1c825d5741f566

Blocking S1P4 signaling attenuates brain injury in mice with ischemic stroke

Autoren: Nikita Basnet Hyunkyung Cho Arjun Sapkota et al.

Quelle: Journal of Advanced Research, Vol 78, Iss , Pp 681-702 (2025)

Schlagwörter: S1P4, NXC736, S1P4 knockdown, Ischemic stroke, Microglia, NLRP3 inflammasome activation, Medicine (General), R5-920, Science (General), Q1-390

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2090123225001109; https://doaj.org/toc/2090-1232

Zugangs-URL: https://doaj.org/article/de8e118e37b943d6b1e61059b2b101f9

Apium graveolens L. alleviates acute lung injury in human A-549 cells by reducing NF-κB and NLRP3 inflammasome signaling

Autoren: Lan-Chi Hsieh Shu-Ling Hsieh Tsu-Ni Ping et al.

Quelle: Pharmaceutical Biology, Vol 63, Iss 1, Pp 1-13 (2025)

Schlagwörter: Apium graveolens L. (celery, acute lung injury, apoptosis, NF-κB, NLRP3 inflammasome, Therapeutics. Pharmacology, RM1-950

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1388-0209; https://doaj.org/toc/1744-5116

Zugangs-URL: https://doaj.org/article/3d11a05c3cc245e3859d634de9b0f899

HHQG ameliorates acute liver injury (ALI) by inhibiting NLRP3 activation through RASD1-mediated regulation of the PKCδ-NF-κB signaling pathway

Autoren: Chunli Ma Linghong Wang Lili Cao et al.

Quelle: Scientific Reports, Vol 15, Iss 1, Pp 1-18 (2025)

Schlagwörter: Traditional mongolian medicine, Acute liver injury, Network pharmacology, RASD1, NLRP3 inflammasome, Medicine, Science

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2045-2322

Zugangs-URL: https://doaj.org/article/ed67f04e2c5547f3b3801df03f83e196

Radiation meets inflammation: NLRP3 inflammasome at the core of radiation-induced cardiac injury

Autoren: Caterina Boncompagni Stefania Giacovazzi Mariasole Perrone et al.

Quelle: Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-15 (2025)

Schlagwörter: NLRP3 inflammasome, Cardiovascular disease, Radiotherapy, Inhibitors, Medicine

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1479-5876

Zugangs-URL: https://doaj.org/article/f2e3dc67863b4322b9a0191557e1a914

ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity

Autoren: Hualong Lin Xinxin Liang Weijie Hao et al.

Quelle: Molecular Biomedicine, Vol 6, Iss 1, Pp 1-14 (2025)

Schlagwörter: ML345, NLRP3 inflammasome, NLRP3 inhibitor, NEK7, Inflammatory diseases, Miscarriage, Medicine

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2662-8651

Zugangs-URL: https://doaj.org/article/764e4999951e447885012e4aa62f5b5a

PROM2 exacerbates CCl4-Induced liver fibrosis via NLRP3 inflammasome activation and hepatocyte pyroptosis

Autoren: Jiashi Guo Yan Lin Xia Gong et al.

Quelle: Cellular and Molecular Life Sciences, Vol 82, Iss 1, Pp 1-19 (2025)

Schlagwörter: Liver fibrosis, PROM2, NLRP3 inflammasome, EMT, Pyroptosis, Biology (General), QH301-705.5, Microbiology, QR1-502

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1420-9071

Zugangs-URL: https://doaj.org/article/5fe213b5fd5042e8a11df068d20c3b64

Enterococcus-derived cytolysin exacerbates ischemic stroke by disrupting the blood–brain barrier via NLRP3 activation

Autoren: Jia-ni Huang Wei-hao Zhuang Yi-si Lin et al.

Quelle: Journal of Neuroinflammation, Vol 22, Iss 1, Pp 1-20 (2025)

Schlagwörter: Ischemic stroke, Cytolysin, Blood–brain barrier (BBB), NLRP3 inflammasome, Neuroprotection, Neurology. Diseases of the nervous system, RC346-429

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1742-2094

Zugangs-URL: https://doaj.org/article/1d1ba048893d420e963ded7689dcbe3e

Screening and validation of key molecular targets for dihydromyricetin in ameliorating diabetic nephropathy

Autoren: LIU Xingran NIU Mengzhu

Quelle: 陆军军医大学学报, Vol 47, Iss 21, Pp 2663-2677 (2025)

Schlagwörter: diabetic nephropathy, dihydromyricetin, pyroptosis, nlrp3 inflammasome, Medicine (General), R5-920

Dateibeschreibung: electronic resource

Relation: https://aammt.tmmu.edu.cn/html/202507095.html; https://doaj.org/toc/2097-0927

Zugangs-URL: https://doaj.org/article/dfff36bbbc8b4b36a5baa7f88d169492

Glycochenodeoxycholic acid induces the release of IL-1beta from L02 cells via the NLRP3/caspase-1/GSDMD pathway to activate LX2 cells

Autoren: Li J Han L Feng S et al.

Quelle: Journal of Inflammation Research, Vol 18, Iss Issue 1, Pp 15429-15440 (2025)

Schlagwörter: Glycochenodeoxycholic acid, NLRP3 inflammasome, Pyroptosis, Gasdermin D, Interleukin-1beta, Hepatic stellate cell, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

Dateibeschreibung: electronic resource

Relation: https://www.dovepress.com/glycochenodeoxycholic-acid-induces-the-release-of-il-1beta-from-l02-ce-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Zugangs-URL: https://doaj.org/article/45aeba63e4ec46bfa4d56bdaacae649f