Search Results - "NICOTINAMIDE"

Effects of Nicotinamide Mononucleotide Supplementation and Aerobic Exercise on Metabolic Health and Physical Performance in Aged Mice.

Authors: Hsu YJ Lee MC Fan HY et al.

Source: Nutrients [Nutrients] 2025 Oct 02; Vol. 17 (19). Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

MeSH Terms: Physical Conditioning, Animal*/physiology , Dietary Supplements* , Nicotinamide Mononucleotide*/pharmacology , Nicotinamide Mononucleotide*/administration & dosage , Aging*/physiology , Physical Functional Performance*, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Nicotinamide Phosphoribosyltransferase/blood ; Nicotinamide Phosphoribosyltransferase/metabolism ; Sirtuin 1/metabolism ; Sirtuin 1/genetics ; Muscle Strength/drug effects ; Energy Metabolism/drug effects ; Physical Endurance/drug effects ; Cytokines/blood

Vascular Endothelial NAMPT-Mediated NAD ⁺ Biosynthesis Regulates Angiogenesis and Cardiometabolic Functions in Male Mice.

Authors: Kosugi S Yamaguchi S Nishioka K et al.

Source: Aging cell [Aging Cell] 2025 Nov; Vol. 24 (11), pp. e70222. Date of Electronic Publication: 2025 Sep 29.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

MeSH Terms: Nicotinamide Phosphoribosyltransferase*/metabolism , Nicotinamide Phosphoribosyltransferase*/genetics , NAD*/biosynthesis , NAD*/metabolism , Cytokines*/metabolism , Neovascularization, Physiologic* , Endothelial Cells*/metabolism, Animals ; Male ; Mice ; Mice, Knockout ; Sirtuin 1/metabolism ; Mice, Inbred C57BL ; Nitric Oxide Synthase Type III/metabolism ; Nicotinamide Mononucleotide ; Angiogenesis

Biochemical and structural characterization of a novel nicotinamide mononucleotide adenylyltransferase from thermophilic fungi Chaetomium thermophilum.

Authors: Qian XL Li JY Li CX et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Aug 30; Vol. 776, pp. 152192. Date of Electronic Publication: 2025 Jun 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH Terms: Chaetomium*/enzymology , Nicotinamide-Nucleotide Adenylyltransferase*/chemistry , Nicotinamide-Nucleotide Adenylyltransferase*/metabolism , Fungal Proteins*/chemistry , Fungal Proteins*/metabolism, Crystallography, X-Ray ; Enzyme Stability ; Models, Molecular ; Nicotinamide Mononucleotide/metabolism ; Nicotinamide Mononucleotide/chemistry ; Substrate Specificity ; Kinetics ; Hydrogen-Ion Concentration ; Catalytic Domain ; Temperature ; NAD ; Amino Acid Sequence

SCR Organism: Chaetomium thermophilum

Enhancing nicotinamide mononucleotide production in Escherichia coli through systematic metabolic engineering.

Authors: Zhang Z Liu J Wang M et al.

Source: Journal of biotechnology [J Biotechnol] 2025 Jul; Vol. 403, pp. 73-80. Date of Electronic Publication: 2025 Mar 27.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8411927 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4863 (Electronic) Linking ISSN: 01681656 NLM ISO Abbreviation: J Biotechnol Subsets: MEDLINE

MeSH Terms: Escherichia coli*/metabolism , Escherichia coli*/genetics , Metabolic Engineering*/methods , Nicotinamide Mononucleotide*/metabolism , Nicotinamide Mononucleotide*/biosynthesis, Glucose/metabolism ; Pentose Phosphate Pathway/genetics ; Nicotinamide Phosphoribosyltransferase/genetics ; Nicotinamide Phosphoribosyltransferase/metabolism

Single bolus injection of nicotinamide mono nucleotide increases systemic insulin sensitivity in association with activation of NAD salvage pathway in the liver and adipose tissue in mice.

Authors: Hiroshige S Kajimura Y Nagao Y et al.

Source: Endocrine journal [Endocr J] 2025 Sep 05; Vol. 72 (9), pp. 1051-1060. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article

Journal Info: Publisher: Japan Endocrine Society Country of Publication: Japan NLM ID: 9313485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4540 (Electronic) Linking ISSN: 09188959 NLM ISO Abbreviation: Endocr J Subsets: MEDLINE

MeSH Terms: Insulin Resistance*/physiology , Liver*/metabolism , Liver*/drug effects , NAD*/metabolism , Adipose Tissue*/metabolism , Adipose Tissue*/drug effects , Nicotinamide Mononucleotide*/administration & dosage , Nicotinamide Mononucleotide*/pharmacology, Animals ; Mice ; Male ; Nicotinamide Phosphoribosyltransferase/metabolism ; Nicotinamide Phosphoribosyltransferase/genetics ; Sirtuin 1/metabolism ; Sirtuin 1/genetics ; Mice, Inbred C57BL ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/drug effects ; Fatty Acids, Nonesterified/blood ; Insulin/metabolism ; Glucose Tolerance Test ; Cytokines/metabolism ; Cytokines/genetics

Reverse Effects of Nicotinamide Mononucleotide Supplementation on Declining Quality of Oocytes With Polycystic Ovary Syndrome.

Authors: Fan Y Hu Q Wu X et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Jul 31; Vol. 39 (14), pp. e70846.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH Terms: Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/drug therapy , Polycystic Ovary Syndrome*/pathology , Oocytes*/drug effects , Oocytes*/metabolism , Oocytes*/pathology , Nicotinamide Mononucleotide*/pharmacology, Female ; Animals ; Mice ; NAD/metabolism ; Oxidative Stress/drug effects ; Nicotinamide-Nucleotide Adenylyltransferase/metabolism ; In Vitro Oocyte Maturation Techniques ; Sirtuin 1/metabolism ; Mitochondria/metabolism ; Mitochondria/drug effects

Nicotinamide Mononucleotide Production in Metabolically Engineered Saccharomyces cerevisiae .

Authors: Cabulong RB Oh WG Naaz T et al.

Source: ACS synthetic biology [ACS Synth Biol] 2025 Jun 20; Vol. 14 (6), pp. 2053-2063. Date of Electronic Publication: 2025 May 09.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

MeSH Terms: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Metabolic Engineering*/methods , Nicotinamide Mononucleotide*/biosynthesis , Nicotinamide Mononucleotide*/genetics , Nicotinamide Mononucleotide*/metabolism, Promoter Regions, Genetic/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Nicotinamide Phosphoribosyltransferase/genetics ; Nicotinamide Phosphoribosyltransferase/metabolism ; Plasmids/genetics ; Plasmids/metabolism ; Humans ; NAD/metabolism ; Fermentation ; Ribose-Phosphate Pyrophosphokinase/genetics ; Ribose-Phosphate Pyrophosphokinase/metabolism ; Cytokines

The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress.

Authors: Zu Y Wu C Li F et al.

Source: Molecular cell [Mol Cell] 2025 Jun 19; Vol. 85 (12), pp. 2271-2286.e6. Date of Electronic Publication: 2025 Jun 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

MeSH Terms: Nicotinamide Phosphoribosyltransferase*/metabolism , Nicotinamide Phosphoribosyltransferase*/genetics , Nicotinamide Phosphoribosyltransferase*/chemistry , Adenosine Triphosphate*/metabolism , Cytokines*/metabolism , Cytokines*/genetics , Cytokines*/chemistry , Adenosine Monophosphate*/metabolism , Energy Metabolism*, Animals ; Mice ; NAD/metabolism ; Humans ; Mice, Inbred C57BL ; Liver/enzymology ; Liver/metabolism ; Male ; HEK293 Cells ; Nicotinamide Mononucleotide/metabolism ; Signal Transduction ; Stress, Physiological ; Protein Binding ; Fasting/metabolism

Efficient Conversion of Nicotinamide Mononucleotide Based on Elucidation of the Limitations in Multienzyme Cascade Reactions.

Authors: Yu F Li H Li X et al.

Source: Biotechnology journal [Biotechnol J] 2025 Feb; Vol. 20 (2), pp. e202400707.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J Subsets: MEDLINE

MeSH Terms: Nicotinamide Mononucleotide*/metabolism , Nicotinamide Mononucleotide*/chemistry, Nicotinamide Phosphoribosyltransferase/metabolism ; Adenosine Triphosphate/metabolism ; Pyrophosphatases/metabolism ; NAD/metabolism ; Adenosine Diphosphate/metabolism ; Hydrolysis ; Phosphoribosyl Pyrophosphate/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Ribose/metabolism

Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic.

Authors: Huang Y Zhang J Zhang W et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Feb 25; Vol. 122 (8), pp. e2424906122. Date of Electronic Publication: 2025 Feb 18.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH Terms: Armadillo Domain Proteins*/metabolism , Armadillo Domain Proteins*/chemistry , Armadillo Domain Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/chemistry , Cytoskeletal Proteins*/genetics , Axons*/metabolism , Axons*/pathology , Nicotinamide Mononucleotide*/metabolism , Nerve Degeneration*/metabolism, Animals ; Cell Death ; Humans ; NAD/metabolism ; Mice ; Cryoelectron Microscopy ; Nicotinamide Phosphoribosyltransferase/metabolism

Nampt/SIRT2/LDHA pathway-mediated lactate production regulates follicular dysplasia in polycystic ovary syndrome.

Authors: Liu K Wei H Nong W et al.

Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Nov 20; Vol. 225, pp. 776-793. Date of Electronic Publication: 2024 Nov 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH Terms: Polycystic Ovary Syndrome*/metabolism , Polycystic Ovary Syndrome*/pathology , Polycystic Ovary Syndrome*/genetics , Polycystic Ovary Syndrome*/drug therapy , Nicotinamide Phosphoribosyltransferase*/metabolism , Nicotinamide Phosphoribosyltransferase*/genetics , Sirtuin 2*/metabolism , Sirtuin 2*/genetics , Granulosa Cells*/metabolism , Granulosa Cells*/drug effects , Granulosa Cells*/pathology , Signal Transduction*, Female ; Animals ; Rats ; Humans ; Nicotinamide Mononucleotide/pharmacology ; Nicotinamide Mononucleotide/metabolism ; Cytokines/metabolism ; Cytokines/genetics ; Lactic Acid/metabolism ; Ovarian Follicle/metabolism ; Ovarian Follicle/pathology ; Ovarian Follicle/drug effects ; Disease Models, Animal ; Letrozole/pharmacology ; NAD/metabolism ; Glycolysis/drug effects ; Rats, Sprague-Dawley ; Lactate Dehydrogenase 5/metabolism ; Acrylamides ; L-Lactate Dehydrogenase ; Piperidines

High-Level Production of Nicotinamide Mononucleotide by Engineered Escherichia Coli .

Authors: Gan J Chen X He Y et al.

Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Dec 25; Vol. 72 (51), pp. 28360-28368. Date of Electronic Publication: 2024 Dec 10.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

MeSH Terms: Escherichia coli*/genetics , Escherichia coli*/metabolism , Nicotinamide Mononucleotide*/metabolism , Metabolic Engineering*, Nicotinamide Phosphoribosyltransferase/genetics ; Nicotinamide Phosphoribosyltransferase/metabolism ; Bioreactors

The structural Basis of NMN synthesis catalyzed by NadV from Haemophilus ducreyi.

Authors: Wang ZJ Yuan J Tang L

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Dec 17; Vol. 738, pp. 150889. Date of Electronic Publication: 2024 Oct 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH Terms: Nicotinamide Phosphoribosyltransferase*/metabolism , Nicotinamide Phosphoribosyltransferase*/chemistry , Nicotinamide Phosphoribosyltransferase*/genetics , Haemophilus ducreyi*/metabolism , Haemophilus ducreyi*/genetics, Models, Molecular ; Nicotinamide Mononucleotide/metabolism ; Nicotinamide Mononucleotide/chemistry ; Catalytic Domain ; Escherichia coli/metabolism ; Escherichia coli/genetics ; NAD/metabolism ; Bacterial Proteins/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Protein Conformation

De novo biosynthesis and nicotinamide biotransformation of nicotinamide mononucleotide by engineered yeast cells.

Authors: Ren Y Han B Wang S et al.

Source: Microbial biotechnology [Microb Biotechnol] 2024 Nov; Vol. 17 (11), pp. e70048.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101316335 Publication Model: Print Cited Medium: Internet ISSN: 1751-7915 (Electronic) Linking ISSN: 17517915 NLM ISO Abbreviation: Microb Biotechnol Subsets: MEDLINE

MeSH Terms: Nicotinamide Mononucleotide*/metabolism , Metabolic Engineering*/methods , Biotransformation* , Niacinamide*/metabolism , Niacinamide*/genetics, Ethanol/metabolism ; Bioreactors/microbiology ; Biosynthetic Pathways/genetics ; Glucose/metabolism ; Nicotinamide Phosphoribosyltransferase/metabolism ; Nicotinamide Phosphoribosyltransferase/genetics ; Saccharomycetales/metabolism ; Saccharomycetales/genetics

SCR Organism: Komagataella pastoris

FOXO1-NMNAT3 axis dysregulation promotes doxorubicin cardiotoxicity: NAD ⁺ replenishment as a redox-targeted antioxidant therapy.

Authors: Cheng F Zhao M Wang Q et al.

Source: Redox report : communications in free radical research [Redox Rep] 2025 Dec; Vol. 30 (1), pp. 2565033. Date of Electronic Publication: 2025 Sep 29.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-2928 (Electronic) Linking ISSN: 13510002 NLM ISO Abbreviation: Redox Rep Subsets: MEDLINE

MeSH Terms: Doxorubicin*/adverse effects , Doxorubicin*/toxicity , NAD*/metabolism , Cardiotoxicity*/metabolism , Cardiotoxicity*/drug therapy , Forkhead Box Protein O1*/metabolism , Forkhead Box Protein O1*/genetics , Nicotinamide-Nucleotide Adenylyltransferase*/metabolism , Nicotinamide-Nucleotide Adenylyltransferase*/genetics , Antioxidants*/pharmacology, Animals ; Mice ; Oxidation-Reduction/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/drug effects ; Humans ; Mice, Inbred C57BL ; Oxidative Stress/drug effects ; Male

Exploring the De Novo NMN Biosynthesis as an Alternative Pathway to Enhance NMN Production.

Authors: Wang P Ma Y Li J et al.

Source: ACS synthetic biology [ACS Synth Biol] 2024 Aug 16; Vol. 13 (8), pp. 2425-2435. Date of Electronic Publication: 2024 Jul 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

MeSH Terms: Escherichia coli*/metabolism , Escherichia coli*/genetics , Nicotinamide Mononucleotide*/metabolism , Metabolic Engineering*/methods , NAD*/metabolism, Escherichia coli Proteins/metabolism ; Escherichia coli Proteins/genetics ; Nicotinamide Phosphoribosyltransferase/metabolism ; Nicotinamide Phosphoribosyltransferase/genetics ; Biosynthetic Pathways/genetics

Microbial creation of β-Nicotinamide mononucleotide and its regulation of lipid metabolism in the liver of high-fat diet mice.

Authors: Tian X Rong Y Luo J et al.

Source: Cell biochemistry and function [Cell Biochem Funct] 2024 Jul; Vol. 42 (5), pp. e4087.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8305874 Publication Model: Print Cited Medium: Internet ISSN: 1099-0844 (Electronic) Linking ISSN: 02636484 NLM ISO Abbreviation: Cell Biochem Funct Subsets: MEDLINE

MeSH Terms: Nicotinamide Mononucleotide*/metabolism , Nicotinamide Mononucleotide*/pharmacology , Lipid Metabolism*/drug effects , Diet, High-Fat* , Liver*/metabolism , Mice, Inbred C57BL*, Animals ; Mice ; Male ; Nicotinamide Phosphoribosyltransferase/metabolism

Enhancing production of nicotinamide mononucleotide by metabolic engineering and flow cytometry screening of Escherichia coli.

Authors: Yang L Wei Y Yang S et al.

Source: Biotechnology letters [Biotechnol Lett] 2025 Nov 06; Vol. 47 (6), pp. 127. Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8008051 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6776 (Electronic) Linking ISSN: 01415492 NLM ISO Abbreviation: Biotechnol Lett Subsets: MEDLINE

MeSH Terms: Escherichia coli*/metabolism , Escherichia coli*/genetics , Metabolic Engineering*/methods , Nicotinamide Mononucleotide*/biosynthesis , Nicotinamide Mononucleotide*/metabolism, Flow Cytometry/methods ; Plasmids/genetics ; Ribose/metabolism

Small Molecule Inhibitors of Nicotinamide N-Methyltransferase Enzyme for the Treatment of Osteosarcoma and Merkel Cell Carcinoma: Potential for the Development of a Targeted Therapeutic Strategy.

Authors: Pompei V Cecati M Serritelli EN et al.

Source: Biomolecules [Biomolecules] 2025 Nov 05; Vol. 15 (11). Date of Electronic Publication: 2025 Nov 05.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH Terms: Osteosarcoma*/drug therapy , Osteosarcoma*/metabolism , Osteosarcoma*/pathology , Osteosarcoma*/enzymology , Nicotinamide N-Methyltransferase*/antagonists & inhibitors , Nicotinamide N-Methyltransferase*/metabolism , Carcinoma, Merkel Cell*/drug therapy , Carcinoma, Merkel Cell*/metabolism , Carcinoma, Merkel Cell*/pathology , Carcinoma, Merkel Cell*/enzymology , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Bone Neoplasms*/drug therapy , Small Molecule Libraries*/pharmacology , Small Molecule Libraries*/chemistry, Humans ; Cell Line, Tumor ; Apoptosis/drug effects ; Reactive Oxygen Species/metabolism ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cisplatin/pharmacology

NAD Metabolism Regulates Proliferation of Macrophages in Atherosclerosis.

Authors: Sinha SK Swichkow CR Farahi L et al.

Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Nov; Vol. 45 (11), pp. 1997-2014. Date of Electronic Publication: 2025 Sep 11.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

MeSH Terms: NAD*/metabolism , Cell Proliferation* , Atherosclerosis*/pathology , Atherosclerosis*/genetics , Atherosclerosis*/metabolism , Atherosclerosis*/prevention & control , Atherosclerosis*/enzymology , Macrophages*/pathology , Macrophages*/metabolism , Macrophages*/enzymology , Nicotinamide N-Methyltransferase*/genetics , Nicotinamide N-Methyltransferase*/metabolism , Nicotinamide N-Methyltransferase*/deficiency , Nicotinamide N-Methyltransferase*/antagonists & inhibitors , Aortic Diseases*/pathology , Aortic Diseases*/genetics , Aortic Diseases*/prevention & control , Aortic Diseases*/enzymology, Animals ; Apoptosis ; Male ; Female ; Mice, Knockout ; Disease Models, Animal ; Mice, Inbred C57BL ; Cells, Cultured ; Mice ; Bone Marrow Transplantation ; Mice, Knockout, ApoE