Výsledky vyhľadávania - "NFATC Transcription Factors"

Shisiwei Jianzhong decoction inhibits the adipogenic differentiation of bone marrow mesenchymal stem cells by downregulating nuclear factor of activated T cells, cytoplasmic 4 in non-severe aplastic anemia.

Autori: Jun W Bo W Yun Z a ďalší

Zdroj: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2025 Oct; Vol. 45 (5), pp. 963-969.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academy Of Traditional Chinese Medicine Country of Publication: China NLM ID: 8211546 Publication Model: Print Cited Medium: Internet ISSN: 2589-451X (Electronic) Linking ISSN: 02552922 NLM ISO Abbreviation: J Tradit Chin Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/administration & dosage , Anemia, Aplastic*/genetics , Anemia, Aplastic*/metabolism , Anemia, Aplastic*/drug therapy , Anemia, Aplastic*/physiopathology , NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/metabolism , Adipogenesis*/drug effects , Bone Marrow Cells*/cytology , Bone Marrow Cells*/drug effects , Bone Marrow Cells*/metabolism, Humans ; Male ; Female ; Adult ; Down-Regulation/drug effects ; PPAR gamma/metabolism ; PPAR gamma/genetics ; Young Adult ; Adolescent ; Middle Aged ; Fatty Acid-Binding Proteins/genetics ; Fatty Acid-Binding Proteins/metabolism ; Cell Differentiation/drug effects ; Apoptosis/drug effects ; Child

Overexpression of Nuclear Factor of Activated T-cells (NFAT) Transcription Factors Drives Chemoresistance and Poor Outcomes in Pancreatic Cancer.

Autori: Kamioka Y Hiroshima Y Kawase W a ďalší

Zdroj: Annals of surgical oncology [Ann Surg Oncol] 2025 Dec; Vol. 32 (13), pp. 10179-10192. Date of Electronic Publication: 2025 Aug 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Drug Resistance, Neoplasm* , Carcinoma, Pancreatic Ductal*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Neoplasm Recurrence, Local*/pathology , Neoplasm Recurrence, Local*/metabolism , Neoplasm Recurrence, Local*/drug therapy , Neoplasm Recurrence, Local*/genetics, Humans ; Male ; Female ; Animals ; Survival Rate ; Prognosis ; Mice ; Middle Aged ; Follow-Up Studies ; Tumor Cells, Cultured ; Gene Expression Regulation, Neoplastic ; Signal Transduction ; Xenograft Model Antitumor Assays ; Aged ; Cell Proliferation ; Transcription Factors

NFATc1-targeted siRNA microdroplets prevent radiation-induced osteoporosis by coordinating bone-immune crosstalk.

Autori: Zhang Y Zhang L Yang X a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 01; Vol. 240, pp. 546-558. Date of Electronic Publication: 2025 Aug 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/antagonists & inhibitors , Osteoporosis*/prevention & control , Osteoporosis*/etiology , Osteoporosis*/pathology , Osteoporosis*/genetics , RNA, Small Interfering*/genetics , RNA, Small Interfering*/administration & dosage, Animals ; Mice ; RAW 264.7 Cells ; Osteogenesis/drug effects ; Osteogenesis/genetics ; Rats ; Osteoclasts/metabolism ; Osteoclasts/radiation effects ; Osteoclasts/drug effects ; Humans ; Tumor Necrosis Factor-alpha/genetics ; Cathepsin K/genetics ; Male ; Cell Differentiation ; Bone Resorption/prevention & control ; Mesenchymal Stem Cells ; Adipogenesis ; Bone and Bones/radiation effects ; Rats, Sprague-Dawley

Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.

Autori: Ding R Hu N Zhang X a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 01; Vol. 240, pp. 15-28. Date of Electronic Publication: 2025 Aug 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/metabolism , Microglia*/metabolism , Microglia*/pathology , Calcineurin*/metabolism , Calcineurin*/genetics , Sepsis-Associated Encephalopathy*/pathology , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/genetics , Smad2 Protein*/metabolism , Smad2 Protein*/genetics , Cognitive Dysfunction*/pathology , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/metabolism , Neuroinflammatory Diseases*/pathology , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/etiology , Sepsis*/complications, Animals ; Mice ; Autophagy ; Signal Transduction ; Lipopolysaccharides ; Male ; Hippocampus/pathology ; Hippocampus/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Mice, Knockout

NFATc3 and PML synergistically regulate tumor-associated gene expression in a SUMOylation-Independent manner.

Autori: Kang T Huang R Wang R a ďalší

Zdroj: Biochimie [Biochimie] 2025 Dec; Vol. 239 (Pt B), pp. 207-217. Date of Electronic Publication: 2025 Sep 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 1264604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1638-6183 (Electronic) Linking ISSN: 03009084 NLM ISO Abbreviation: Biochimie Subsets: MEDLINE

Výrazy zo slovníka MeSH: Promyelocytic Leukemia Protein*/metabolism , Promyelocytic Leukemia Protein*/genetics , Sumoylation* , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Gene Expression Regulation, Neoplastic*, Humans ; HEK293 Cells

JNK knockdown enhances CAR-T cell cytotoxicity through elevated NFATc1-dependent transcription in preclinical ovarian cancer models.

Autori: Kuhlmann CJ Jepson CE Blucas MT a ďalší

Zdroj: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Nov 18; Vol. 13 (11). Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/therapy , Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/pathology , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Receptors, Chimeric Antigen*/metabolism , Immunotherapy, Adoptive*/methods , JNK Mitogen-Activated Protein Kinases*/genetics , JNK Mitogen-Activated Protein Kinases*/metabolism, Humans ; Female ; Animals ; Mice ; Xenograft Model Antitumor Assays ; Gene Knockdown Techniques ; Cell Line, Tumor

[Research on the negative regulation of osteoclast differentiation by hairy and enhancer of split related protein 2 through nuclear factor of activated T cells cytoplasmic 1].

Autori: Qiao ZX Ban Y Liu LL a ďalší

Zdroj: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology [Zhonghua Kou Qiang Yi Xue Za Zhi] 2025 Nov 09; Vol. 60 (11), pp. 1247-1256.

Spôsob vydávania: English Abstract; Journal Article

Informácie o časopise: Publisher: Chinese Medical Association Country of Publication: China NLM ID: 8711066 Publication Model: Print Cited Medium: Print ISSN: 1002-0098 (Print) Linking ISSN: 10020098 NLM ISO Abbreviation: Zhonghua Kou Qiang Yi Xue Za Zhi Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoclasts*/cytology , Osteoclasts*/metabolism , Cell Differentiation*/drug effects , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics, Animals ; Mice ; RANK Ligand/pharmacology ; Cathepsin K/metabolism ; Tartrate-Resistant Acid Phosphatase/metabolism ; RAW 264.7 Cells ; Proto-Oncogene Proteins c-fos/metabolism

NFATc1 drives Orai3 transcription and proteolysis by harnessing epigenome differences in the MARCH8 promoter.

Autori: Raju S Sharma A Dahiya S a ďalší

Zdroj: The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (21), pp. 6137-6167. Date of Electronic Publication: 2025 Sep 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Promoter Regions, Genetic* , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Ubiquitin-Protein Ligases*/genetics , Ubiquitin-Protein Ligases*/metabolism , Calcium Channels*/genetics , Calcium Channels*/metabolism , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/pathology , Transcription, Genetic* , Epigenesis, Genetic* , Gene Expression Regulation, Neoplastic*, Humans ; Proteolysis ; Cell Line, Tumor ; Ubiquitination ; HEK293 Cells

Histone lactylation promotes rheumatoid arthritis progression by increasing NFATc2 expression and the production of anti-lactylated histone autoantibodies.

Autori: Wu G Yang C Huang Y a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Oct 10; Vol. 16 (1), pp. 9034. Date of Electronic Publication: 2025 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Histones*/metabolism , Histones*/immunology , Arthritis, Rheumatoid*/immunology , Arthritis, Rheumatoid*/metabolism , Arthritis, Rheumatoid*/pathology , Arthritis, Rheumatoid*/genetics , Autoantibodies*/immunology , Autoantibodies*/metabolism , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Lactic Acid*/metabolism, Humans ; Animals ; Disease Progression ; Mice ; Male ; Female ; Arthritis, Experimental/immunology ; Arthritis, Experimental/pathology ; Synovial Membrane/metabolism ; Synovial Membrane/pathology ; Synovial Membrane/immunology ; Middle Aged ; Disease Models, Animal

NFATc1 regulates LAG3+CD8+ T cells in the spleen of mice infected with Plasmodium yoelii NSM.

Autori: Pan X Mo F Pan L a ďalší

Zdroj: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Oct 06; Vol. 19 (10), pp. e0013605. Date of Electronic Publication: 2025 Oct 06 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Plasmodium yoelii*/immunology , CD8-Positive T-Lymphocytes*/immunology , Malaria*/immunology , Malaria*/parasitology , Spleen*/immunology , NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/immunology , Antigens, CD*/genetics , Antigens, CD*/metabolism , Antigens, CD*/immunology, Animals ; Mice ; Mice, Inbred C57BL ; Lymphocyte Activation Gene 3 Protein ; Female

Obesity Impacts Post-Myocardial Infarction Neovascularization by Downregulating AQP1 Expression via the TRPC5-NFATc3 Signaling Pathway.

Autori: Gao M Han J Zhu Y a ďalší

Zdroj: Comprehensive Physiology [Compr Physiol] 2025 Oct; Vol. 15 (5), pp. e70048.

Spôsob vydávania: Journal Article

Informácie o časopise: Country of Publication: United States NLM ID: 101574442 Publication Model: Print Cited Medium: Internet ISSN: 2040-4603 (Electronic) Linking ISSN: 20404603 NLM ISO Abbreviation: Compr Physiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myocardial Infarction*/metabolism , TRPC Cation Channels*/metabolism , TRPC Cation Channels*/genetics , Obesity*/metabolism , Obesity*/complications , Aquaporin 1*/metabolism , Aquaporin 1*/genetics , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics, Animals ; Mice ; Signal Transduction/physiology ; Down-Regulation ; Male ; Mice, Inbred C57BL ; Humans ; Neovascularization, Physiologic ; Endothelial Cells/metabolism

Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NFκB and NFAT pathways.

Autori: Berschneider KM Wetterauer B Sticht C a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 15; Vol. 16, pp. 1655212. Date of Electronic Publication: 2025 Oct 15 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Plant Extracts*/pharmacology , Arnica*/chemistry , NF-kappa B*/metabolism , NFATC Transcription Factors*/metabolism , Lymphocyte Activation*/drug effects , Lymphocyte Activation*/immunology , Signal Transduction*/drug effects , T-Lymphocytes*/immunology , T-Lymphocytes*/drug effects , T-Lymphocytes*/metabolism, Humans ; Cell Proliferation/drug effects ; Cells, Cultured

The m ¹ A-SFRP2-NFAT/TOX axis governs T cell exhaustion in gastric cancer.

Autori: Liu Y Liu G Wang X a ďalší

Zdroj: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2025 Oct; Vol. 48 (5), pp. 1553-1569. Date of Electronic Publication: 2025 Aug 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Stomach Neoplasms*/immunology , Stomach Neoplasms*/genetics , Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , NFATC Transcription Factors*/metabolism , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism, Humans ; Animals ; Cell Line, Tumor ; Tumor Microenvironment ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Signal Transduction ; Mice ; Immune Checkpoint Inhibitors/pharmacology ; T-Cell Exhaustion

USP5 Deletion Inhibits KD Serum Induced-Human Coronary Artery Endothelial Cell Dysfunction by Regulating the NFATC1/TLR4-Mediated NF-κB Signaling Pathway in Kawasaki Disease.

Autori: Yao L Lai Y Li H a ďalší

Zdroj: Inflammation [Inflammation] 2025 Oct; Vol. 48 (5), pp. 3446-3457. Date of Electronic Publication: 2025 Mar 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE

Výrazy zo slovníka MeSH: NFATC Transcription Factors*/metabolism , Mucocutaneous Lymph Node Syndrome*/metabolism , Mucocutaneous Lymph Node Syndrome*/pathology , Mucocutaneous Lymph Node Syndrome*/blood , Toll-Like Receptor 4*/metabolism , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Coronary Vessels*/pathology , Coronary Vessels*/metabolism , NF-kappa B*/metabolism , Ubiquitin-Specific Proteases*/deficiency , Ubiquitin-Specific Proteases*/genetics , Ubiquitin-Specific Proteases*/metabolism, Humans ; Signal Transduction/physiology ; Cells, Cultured ; Apoptosis ; Cell Proliferation

Macrophage-derived NPS drives acute lung injury by inducing CaMKII/NFATc3-Mediated M1 polarization.

Autori: Wang Z Li J Yu Z a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2026 Jan; Vol. 243 (Pt 1), pp. 117490. Date of Electronic Publication: 2025 Oct 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Acute Lung Injury*/metabolism , Acute Lung Injury*/chemically induced , Acute Lung Injury*/pathology , Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism , Macrophages*/metabolism , Macrophages*/drug effects , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Neuropeptides*/metabolism , Neuropeptides*/genetics , Cell Polarity*/physiology, Animals ; Mice ; Lipopolysaccharides/toxicity ; Mice, Inbred C57BL ; Male ; Humans ; RAW 264.7 Cells

GPC2-Targeted CAR T Cells Engineered with NFAT-Inducible Membrane-Tethered IL15/IL21 Exhibit Enhanced Activity against Neuroblastoma.

Autori: Okada R Reyes-González JM Rodriguez C a ďalší

Zdroj: Cancer immunology research [Cancer Immunol Res] 2025 Sep 02; Vol. 13 (9), pp. 1363-1373.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neuroblastoma*/therapy , Neuroblastoma*/immunology , Neuroblastoma*/pathology , Immunotherapy, Adoptive*/methods , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/genetics , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Interleukin-15*/genetics , Interleukin-15*/metabolism , Interleukin-15*/immunology , Glypicans* , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism, Animals ; Mice ; Humans ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Female ; Mice, Inbred NOD

NFATc4 Promotes Lung Adenocarcinoma Progression via the CCNB1/CDK1 Pathway and Is a Potential Prognostic Biomarker.

Autori: Yang W Wu X Cai F a ďalší

Zdroj: Cancer science [Cancer Sci] 2025 Sep; Vol. 116 (9), pp. 2400-2412. Date of Electronic Publication: 2025 Jul 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cyclin B1*/metabolism , Cyclin B1*/genetics , CDC2 Protein Kinase*/metabolism , CDC2 Protein Kinase*/genetics , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/genetics , Adenocarcinoma of Lung*/metabolism , Adenocarcinoma of Lung*/mortality , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics, Humans ; Prognosis ; Cell Proliferation/genetics ; Female ; Male ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Disease Progression ; Middle Aged ; Animals ; Apoptosis/genetics ; Mice ; Signal Transduction

KDM4C regulates trophoblast proliferation and migration in preeclampsia via the NFATc4/Wnt pathway.

Autori: Shao C Jia Y Qiao S a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 Sep; Vol. 321 (Pt 3), pp. 146320. Date of Electronic Publication: 2025 Jul 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Trophoblasts*/metabolism , Trophoblasts*/pathology , Pre-Eclampsia*/metabolism , Pre-Eclampsia*/pathology , Pre-Eclampsia*/genetics , Wnt Signaling Pathway* , NFATC Transcription Factors*/metabolism , NFATC Transcription Factors*/genetics , Cell Movement*/genetics , Jumonji Domain-Containing Histone Demethylases*/metabolism , Jumonji Domain-Containing Histone Demethylases*/genetics, Female ; Pregnancy ; Cell Proliferation ; Animals ; Humans ; Rats ; Cell Line ; Disease Models, Animal

EWSR1::NFATC2 Rearranged Sarcoma : Distinct Clinicopathological Features From a Series of 5 Rare Cases.

Autori: Thirunavukkarasu B Shukla P Pushpam D a ďalší

Zdroj: Applied immunohistochemistry & molecular morphology : AIMM [Appl Immunohistochem Mol Morphol] 2025 Sep 01; Vol. 33 (5), pp. 295-305. Date of Electronic Publication: 2025 Jul 23.

Spôsob vydávania: Journal Article; Case Reports

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100888796 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4058 (Electronic) Linking ISSN: 15334058 NLM ISO Abbreviation: Appl Immunohistochem Mol Morphol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Sarcoma, Ewing*/genetics , Sarcoma, Ewing*/pathology , Sarcoma, Ewing*/metabolism , Sarcoma, Ewing*/diagnosis , RNA-Binding Protein EWS*/genetics , Oncogene Proteins, Fusion*/genetics , Oncogene Proteins, Fusion*/metabolism , Gene Rearrangement* , NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/metabolism , Bone Neoplasms*/genetics , Bone Neoplasms*/pathology, Humans ; Male ; Female ; Homeobox Protein Nkx-2.2 ; Child ; In Situ Hybridization, Fluorescence ; Transcription Factors/metabolism ; Transcription Factors/genetics ; Adolescent ; Adult ; Homeodomain Proteins/metabolism ; Homeodomain Proteins/genetics ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism ; Young Adult ; Nuclear Proteins ; Matrix Attachment Region Binding Proteins

NFATc1 Abrogation in B Cells Ameliorates Contact Hypersensitivity Responses.

Autori: Grän F Azeem M Serfling E a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 22; Vol. 26 (17). Date of Electronic Publication: 2025 Aug 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: NFATC Transcription Factors*/genetics , NFATC Transcription Factors*/metabolism , B-Lymphocytes*/immunology , B-Lymphocytes*/metabolism , Dermatitis, Allergic Contact*/immunology , Dermatitis, Allergic Contact*/metabolism , Dermatitis, Allergic Contact*/pathology , Dermatitis, Contact*/immunology , Dermatitis, Contact*/metabolism, Animals ; Mice ; Disease Models, Animal ; Lymphocyte Activation ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; Mice, Inbred C57BL ; Interleukin-10/metabolism