Výsledky vyhľadávania - "NF-kappa B metabolism"

Sodium butyrate attenuates experimental neonatal necrotizing enterocolitis by suppressing TLR4-mediated NLRP3 inflammasome-dependent pyroptosis

Autori: Gao, Yanan Yang, Liting Wu, Hongya a ďalší

Zdroj: Food & Function. 16:3508-3524

Predmety: Pyroptosis/drug effects, Male, Inflammasomes, Intestinal inflammation, Network pharmacologies, Butyric Acid/administration & dosage, NLR Family, Pyrin Domain-Containing 3 Protein/genetics, Inflammasome, Cell Line, Food science, Rats, Sprague-Dawley, Signalling pathways, Tlr4 protein, rat, Enterocolitis, Necrotizing, Signal Transduction/drug effects, Sciences des denrées alimentaires, NLR Family, Pyrin Domain-Containing 3 Protein, Pyroptosis, Inflammasomes/metabolism, Animals, Humans, Enterocolitis, Necrotizing/genetics, Intestinal barriers, Premature infants, Inflammasomes/drug effects, Butyric Acid/pharmacology, NF-kappa B, Enterocolitis, Necrotizing/metabolism, Sodium butyrate, Enterocolitis, Necrotizing/drug therapy, Life sciences, Rats, Toll-Like Receptor 4, Molecular Docking Simulation, Disease Models, Animal, Toll-Like Receptor 4/metabolism, Animals, Newborn, NF-kappa B/metabolism, Rat model, Sciences du vivant, Neonatal rat, Butyric Acid, Nlrp3 protein, rat, NLR Family, Pyrin Domain-Containing 3 Protein/metabolism, Toll-Like Receptor 4/genetics, Protective effects, Food Science, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40223745
https://hdl.handle.net/2268/332375
https://doi.org/10.1039/d4fo03517h

Discovery of the Alternaria mycotoxins alterperylenol and altertoxin I as novel immunosuppressive and antiestrogenic compounds in vitro

Autori: Crudo, Francesco Partsch, Vanessa Braga, Dennis a ďalší

Zdroj: Arch Toxicol

Predmety: Mycotoxins Toxicity, THP-1 Cells, Biologics, Monocytes, Estrogen Antagonists Toxicity, Lactones, SDG 3 - Good Health and Well-being, Immunosuppressive Agents Toxicity, Tandem Mass Spectrometry, Benz(a)Anthracenes, Benz(a) Anthracenes Toxicity, Humans, 301211 Toxicology, Food contaminants, Lactones Toxicity, NF-kappa B Metabolism, Estrogen Antagonists, NF-kappa B, Alternaria, Mycotoxins, In vitro toxicity, Alternaria mycotoxins, 301211 Toxikologie, SDG 3 – Gesundheit und Wohlergehen, Chemical mixture, Estrogen Antagonists Pharmacology, Immunosuppressive Agents

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39358629
https://hdl.handle.net/11353/10.2137939
https://phaidra.univie.ac.at/o:2137939
https://doi.org/10.1007/s00204-024-03877-1

Constitutive expression of the deubiquitinating enzyme CYLD does not affect microglia phenotype or function in homeostasis and neuroinflammation

Autori: Eva Schramm Vanessa Becker Ilaria Palagi a ďalší

Prispievatelia: Eva Schramm Vanessa Becker Ilaria Palagi a ďalší

Zdroj: J Mol Med (Berl)

Predmety: Lipopolysaccharides, Encephalomyelitis, Autoimmune, Experimental, Deubiquitinating enzyme, NF-κB, Neuroinflammatory Diseases/metabolism [MeSH], Mice, Inbred C57BL [MeSH], Neuroinflammatory Diseases/genetics [MeSH], Neuroinflammation, Microglia, Encephalomyelitis, Autoimmune, Experimental/pathology [MeSH], Lipopolysaccharides [MeSH], Deubiquitinating Enzyme CYLD/genetics [MeSH], Encephalomyelitis, Autoimmune, Experimental/metabolism [MeSH], Encephalomyelitis, Autoimmune, Experimental/genetics [MeSH], CYLD, Animals [MeSH], Original Article, Mice, Transgenic [MeSH], Microglia/metabolism [MeSH], Mice [MeSH], EAE, NF-kappa B/metabolism [MeSH], Deubiquitinating Enzyme CYLD/metabolism [MeSH], Signal Transduction [MeSH], Phenotype [MeSH], Homeostasis [MeSH], 610 Medizin, NF-kappa B, Mice, Transgenic, Deubiquitinating Enzyme CYLD, Mice, Inbred C57BL, Mice, Phenotype, 610 Medical sciences, Neuroinflammatory Diseases, Animals, Homeostasis, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39302418
https://openscience.ub.uni-mainz.de/handle/20.500.12030/12456
https://doi.org/10.25358/openscience-12435
https://repository.publisso.de/resource/frl:6499359

Atheroprotective role of vinpocetine: an old drug with new indication

Autori: Mohammed H. Abu-Alghayth Hayder M. Al-kuraishy Ali I. Al-Gareeb a ďalší

Zdroj: Inflammopharmacology

Predmety: 0301 basic medicine, 0303 health sciences, NF-kappa B, Anti-Inflammatory Agents, Review, Atherosclerosis, Antioxidants, 3. Good health, Oxidative Stress, 03 medical and health sciences, Humans, Animals, Cytokines, Endothelium, Vascular, Antioxidants/pharmacology [MeSH], Endothelial dysfunction, Atherosclerosis/prevention, Humans [MeSH], Cytokines/metabolism [MeSH], Animals [MeSH], Endothelium, Vascular/drug effects [MeSH], Reactive oxygen species, Anti-Inflammatory Agents/pharmacology [MeSH], NF-kappa B/metabolism [MeSH], Vinpocetine, Atherosclerosis/drug therapy [MeSH], Oxidative Stress/drug effects [MeSH], Endothelium, Vascular/metabolism [MeSH], Vinca Alkaloids/pharmacology [MeSH], Atherosclerosis/metabolism [MeSH], Pro-inflammatory cytokines, Vinca Alkaloids

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39141151
https://repository.publisso.de/resource/frl:6495866

Noncanonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y11 receptor

Autori: Ocadlikova, Darina Fiordi, Benedetta Trabanelli, Sara a ďalší

Zdroj: Journal of leukocyte biology, vol. 117, no. 4

Predmety: Adenosine Triphosphate / metabolism, T-Lymphocytes, Regulatory / immunology, 616.07, Indoleamine-2, T-Lymphocytes, Regulatory, NF-kappa B / metabolism, NF-kappa B / immunology, Dendritic Cells/metabolism, Dendritic Cells/immunology, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism, Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics, Adenosine Triphosphate/metabolism, Signal Transduction, NF-kappa B/metabolism, NF-kappa B/immunology, Receptors, Purinergic P2/metabolism, T-Lymphocytes, Regulatory/immunology, T-Lymphocytes, Regulatory/metabolism, 3-dioxygenase 1, ATP, dendritic cell, immune tolerance, indoleamine-2, tumor, Receptors, Purinergic P2 / metabolism, Adenosine Triphosphate, Indoleamine-Pyrrole 2,3,-Dioxygenase / genetics, Dendritic Cells / immunology, Indoleamine-Pyrrole 2,3,-Dioxygenase, Tumor, Receptors, Purinergic P2, Immune tolerance, NF-kappa B, T-Lymphocytes, Regulatory / metabolism, Dendritic Cells, Dendritic Cells / metabolism, Indoleamine-Pyrrole 2,3,-Dioxygenase / metabolism, Dendritic cell

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39899472
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_491A6B46FE349
https://serval.unil.ch/notice/serval:BIB_491A6B46FE34
https://serval.unil.ch/resource/serval:BIB_491A6B46FE34.P001/REF.pdf

Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes

Autori: Alraies, Zahraa Rivera, Claudia Delgado, Maria-Graciela a ďalší

Prispievatelia: Alraies, Zahraa Rivera, Claudia Delgado, Maria-Graciela a ďalší

Zdroj: Nat Immunol
Nature Immunology

Predmety: 0301 basic medicine, Receptors, CCR7, Knockout, [SDV]Life Sciences [q-bio], MESH: Cell Movement / immunology, Inbred C57BL, Article, Actin-Related Protein 2-3 Complex, Mice, 03 medical and health sciences, Cell Movement, MESH: Receptors, MESH: Cell Shape, MESH: Lymph Nodes / immunology, Animals, Homeostasis, MESH: Animals, MESH: NF-kappa B / metabolism, MESH: Dendritic Cells / metabolism, MESH: Mice, Cell Shape, Mice, Knockout, 0303 health sciences, MESH: Actin-Related Protein 2-3 Complex / metabolism, MESH: Signal Transduction / immunology, NF-kappa B, Dendritic Cells, CCR7 / metabolism, MESH: I-kappa B Kinase / metabolism, I-kappa B Kinase, [SDV] Life Sciences [q-bio], Mice, Inbred C57BL, MESH: Homeostasis, MESH: Lymph Nodes / cytology, Lymph Nodes, MESH: Dendritic Cells / immunology, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38834865

Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and immune dysregulation in humans

Autori: Riller, Quentin Sorin, Boris Courteille, Charline a ďalší

Prispievatelia: Riller, Quentin Sorin, Boris Courteille, Charline a ďalší

Zdroj: Journal of Experimental Medicine. 222

Predmety: NFKB2, Immunology, NF-KAPPA-B, BETA, Genetics & genetic processes, Research & Experimental Medicine, Agammaglobulinemia/immunology, MICE LACKING, ACTIVATION, PATHWAY, Génétique & processus génétiques, Protein Domains, Agammaglobulinemia, Immunologic Deficiency Syndromes/immunology, Humans, Agammaglobulinemia/genetics, 11 Medical and Health Sciences, GENE-EXPRESSION, Science & Technology, ERN-RITA, 42 Health sciences, I-kappa B Kinase/metabolism, NF-kappa B, Immunologic Deficiency Syndromes, NF-KAPPA-B2, I-kappa B Kinase/genetics, GERMLINE MUTATIONS, 32 Biomedical and clinical sciences, Life sciences, I-kappa B Kinase, [SDV] Life Sciences [q-bio], Jeffrey Modell Foundation, HEK293 Cells, CHUK protein, human, Medicine, Research & Experimental, NF-kappa B/metabolism, Mutation, Sciences du vivant, T-CELLS, Immunologic Deficiency Syndromes/genetics, Female, Life Sciences & Biomedicine, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39812688
https://hdl.handle.net/2268/327168
https://doi.org/10.1084/jem.20240843
https://hal.science/hal-05080410v1
https://doi.org/10.1084/jem.20240843

Bosutinib stimulates macrophage survival, phagocytosis and intracellular killing of bacteria

Autori: Ronni A. G. da Silva Claudia J. Stocks Guangan Hu a ďalší

Zdroj: ACS Infect Dis

Predmety: Cell Survival / drug effects, Antibiotic resistance, Cell Survival, Wound infection, Macrophages / drug effects, NF-kappa B / metabolism, Immunomodulation, Aniline Compounds / pharmacology, Mice, Phagocytosis, Nitriles, Enterococcus faecalis, Animals, Humans, Enterococcus faecalis / drug effects, Gram-Positive Bacterial Infections, Aniline Compounds, Macrophages, NF-kappa B, Gram-Positive Bacterial Infections / drug therapy, Reactive Oxygen Species / metabolism, Anti-Bacterial Agents / pharmacology, Src kinases targeting, Anti-Bacterial Agents, 3. Good health, Mice, Inbred C57BL, Quinolines, Nitriles / pharmacology, Phagocytosis / drug effects, Reactive Oxygen Species, Quinolines / pharmacology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38602352

Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling

Autori: Peter Kubatka Lenka Koklesova Alena Mazurakova a ďalší

Zdroj: Cancer Metastasis Rev

Predmety: Flavonoids, Phosphatidylinositol 3-Kinases, Cell Line, Tumor, Cell Plasticity, NF-kappa B, Tumor Microenvironment, Humans, Female, Breast Neoplasms, Review, Female [MeSH], Cell Line, Tumor [MeSH], Cell Plasticity [MeSH], Flavonoids/pharmacology [MeSH], Humans [MeSH], Breast Neoplasms/drug therapy [MeSH], Cell plasticity, NF-kappa B/metabolism [MeSH], Flavonoids/therapeutic use [MeSH], Combination anti-cancer therapies, NF-κB signaling, Phosphatidylinositol 3-Kinases/metabolism [MeSH], Signal Transduction [MeSH], Breast carcinoma, Chemo-resistance of cancer, Tumor Microenvironment [MeSH], 3. Good health, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37789138
https://repository.publisso.de/resource/frl:6508570

Synthesis, characterization, and anti-inflammatory potential of serotonin- and dopamine-conjugates of urolithin A

Autori: Maciej Korczak Martina Redl Piotr Roszkowski a ďalší

Zdroj: Biomedicine & Pharmacotherapy. 189:118282

Predmety: Serotonin/chemistry, Inflammation, 106022 Mikrobiologie, Serotonin, 301209 Pharmazie, Caenorhabditis elegans/drug effects, Dopamine, Cytokines/metabolism, 301204 Pharmakognosie, Neurotransmitters, Postbiotic metabolite, Structure derivatization, Urolithin A, Mice, 301209 Pharmacy, Macrophages/drug effects, Signal Transduction/drug effects, Coumarins/pharmacology, NF-kappa B/metabolism, 106022 Microbiology, Animals, Anti-Inflammatory Agents/pharmacology, 301204 Pharmacognosy, Parkinson Disease/drug therapy, Dopamine/chemistry

Pellino-1 promotes intrinsic activation of skin-resident IL-17A–producing T cells in psoriasis

Autori: Sung Hee Kim Jongwook Oh Won Seok Roh a ďalší

Prispievatelia: Sung Hee Kim Jongwook Oh Won Seok Roh a ďalší

Zdroj: Journal of Allergy and Clinical Immunology. 151:1317-1328

Predmety: 0301 basic medicine, Ubiquitin-Protein Ligases, Dermatitis, Nuclear Proteins / genetics, NF-κB, single-cell RNA sequencing, NF-kappa B / metabolism, Mice, 03 medical and health sciences, Humans, Animals, Psoriasis, Ubiquitin-Protein Ligases / genetics, Interleukin-17A, Skin, 0303 health sciences, Animal, Pellino-1, Nuclear Proteins / metabolism, Interleukin-17, NF-kappa B, Nuclear Proteins, psoriasis, skin-resident T cells, 3. Good health, Disease Models, Animal, Disease Models

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36646143

Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates

Autori: Li, Changqing Moro, Stefano Shostak, Kateryna a ďalší

Prispievatelia: Li, Changqing Moro, Stefano Shostak, Kateryna a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Predmety: Science, Amino Acid Motifs, Aucun, Biochimie, biophysique & biologie moléculaire, Article, Substrate Specificity, NF-KappaB Inhibitor alpha, Humans, Phosphorylation, I-kappa B Kinase/metabolism, NF-kappa B, NF-KappaB Inhibitor alpha/genetics, I-kappa B Kinase/genetics, Life sciences, I-kappa B Kinase, Molecular Docking Simulation, HEK293 Cells, NF-kappa B/metabolism, Sciences du vivant, NF-KappaB Inhibitor alpha/metabolism, I-kappa B Kinase/chemistry, Protein Multimerization, Biochemistry, biophysics & molecular biology, Protein Binding, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39227404
https://doaj.org/article/7002b32fa22e4bd38f05d9ec9d049537
https://hdl.handle.net/2268/321940
https://doi.org/10.1038/s41467-024-52076-0
https://www.nature.com/articles/s41467-024-52076-0

Targeting IL-1 controls refractory pityriasis rubra pilaris

Autori: Schmauch, Eloi Severin, Yannik Xing, Xianying a ďalší

Prispievatelia: Schmauch, Eloi Severin, Yannik Xing, Xianying a ďalší

Zdroj: Sci Adv
Science advances, vol. 10, no. 27, pp. eado2365

Predmety: Keratinocytes, Male, Adult, 0301 basic medicine, Interleukin-1beta, Nod2 Signaling Adaptor Protein, 610 Medicine & health, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Humans, Pityriasis Rubra Pilaris/drug therapy, Pityriasis Rubra Pilaris/pathology, Pityriasis Rubra Pilaris/genetics, Interleukin-1beta/metabolism, Interleukin-1beta/antagonists & inhibitors, Interleukin 1 Receptor Antagonist Protein/therapeutic use, Keratinocytes/metabolism, Keratinocytes/drug effects, Keratinocytes/pathology, Antibodies, Monoclonal, Humanized/therapeutic use, Antibodies, Monoclonal, Humanized/pharmacology, NF-kappa B/metabolism, Nod2 Signaling Adaptor Protein/metabolism, Nod2 Signaling Adaptor Protein/genetics, Nod2 Signaling Adaptor Protein/antagonists & inhibitors, Female, CARD Signaling Adaptor Proteins/metabolism, CARD Signaling Adaptor Proteins/genetics, Skin/pathology, Skin/metabolism, Skin/drug effects, Interleukin-1/antagonists & inhibitors, Interleukin-1/metabolism, Interleukin-1/genetics, Middle Aged, Guanylate Cyclase/metabolism, Guanylate Cyclase/antagonists & inhibitors, Guanylate Cyclase/genetics, Signal Transduction/drug effects, Membrane Proteins, Skin, 1000 Multidisciplinary, 0303 health sciences, NF-kappa B, 10177 Dermatology Clinic, 3. Good health, CARD Signaling Adaptor Proteins, Interleukin 1 Receptor Antagonist Protein, Guanylate Cyclase, Pityriasis Rubra Pilaris, Biomedicine and Life Sciences, Interleukin-1, Signal Transduction

Popis súboru: application/pdf; 2024_Schmauch_IL1_PRP_SciAdv.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38959302
https://serval.unil.ch/notice/serval:BIB_C2D3F8232AED
https://serval.unil.ch/resource/serval:BIB_C2D3F8232AED.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C2D3F8232AED6
https://www.zora.uzh.ch/id/eprint/262004/
https://doi.org/10.5167/uzh-262004

Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus

Autori: Jing Zhu Soojin Park Chul Hoon Kim a ďalší

Prispievatelia: Jing Zhu Soojin Park Chul Hoon Kim a ďalší

Zdroj: Experimental Biology and Medicine. 248:722-731

Predmety: hippocampus, phytoconstituent, Inflammasomes, Status Epilepticus* / drug therapy, Status Epilepticus* / chemically induced, Anti-Inflammatory Agents, Seizures / drug therapy, NLR Family, Hippocampus, NF-kappa B / metabolism, 03 medical and health sciences, Status Epilepticus, 0302 clinical medicine, anti-inflammatory effects, Seizures, Eugenol / pharmacology, Eugenol, NLR Family, Pyrin Domain-Containing 3 Protein, Humans, Status Epilepticus* / pathology, Anti-Inflammatory Agents / therapeutic use, status epilepticus, Seizures / chemically induced, Pilocarpine, NF-kappa B, 3. Good health, Pilocarpine* / toxicity, Eugenol / therapeutic use, Hippocampus / metabolism, Pyrin Domain-Containing 3 Protein / metabolism, Seizures / metabolism, Neuroinflammatory Diseases, neuroprotection, Anti-Inflammatory Agents / pharmacology, Inflammasomes / metabolism, Eugenol / metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36802956

Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration

Autori: Irena J.J. Muffels Imre F. Schene Holger Rehmann a ďalší

Prispievatelia: Irena J.J. Muffels Imre F. Schene Holger Rehmann a ďalší

Zdroj: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
Am. J. Hum. Genet. 110, 146-160 (2023)

Predmety: 0301 basic medicine, NEDDYLATION, Proteasome Endopeptidase Complex, NEDD8 Protein, POST-TRANSLATIONAL PROTEIN MODIFICATION, UBIQUITINATION, ubiquitination, PHENOTYPIC SPECIFICITY, 03 medical and health sciences, neddylation, OCURRENCE RATIO, post-translational protein modification, Lymphopenia/genetics, Intellectual Disability, Lymphopenia, Genetics, Journal Article, Humans, Genetics(clinical), PROTEASOME, 0303 health sciences, NEURODEGENERATION, neurodegeneration, NF-kappa B, ocurrence ratio, lymphopenia, phenotypic specificity, Intellectual Disability/genetics, 3. Good health, Proteasome Endopeptidase Complex/metabolism, proteasome, NF-kappa B/metabolism, Signal Transduction/genetics, Nae1, Neddylation, Neurodegeneration, Ocurrence Ratio, Phenotypic Specificity, Post-translational Protein Modification, Proteasome, Ubiquitination, NEDD8 Protein/genetics, NAE1, LYMPHOPENIA, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36608681
https://research.rug.nl/en/publications/7a4cfe00-a044-4183-8238-f4462c41ca55
https://hdl.handle.net/11370/7a4cfe00-a044-4183-8238-f4462c41ca55
https://doi.org/10.1016/j.ajhg.2022.12.003
https://dspace.library.uu.nl/handle/1874/448262
http://hdl.handle.net/11336/218482
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=67154

ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer.

Autori: DiCiaccio, Benedetto Seehawer, Marco Li, Zheqi a ďalší

Zdroj: Cell Reports, 43 (12), 114991 (2024-12-24)

Predmety: CP: Cancer, CRISPR screen, breast cancer, histone demethylase, mitochondrial signaling, Transcription Factors, DNA-Binding Proteins, KDM5A protein, human, ZBTB7A protein, human, Retinoblastoma-Binding Protein 2, Histones, NF-kappa B, Humans, Female, Cell Line, Tumor, Gene Regulatory Networks, Retinoblastoma-Binding Protein 2/metabolism, Retinoblastoma-Binding Protein 2/genetics, Histones/metabolism, Promoter Regions, Genetic/genetics, NF-kappa B/metabolism, Animals, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Breast Neoplasms/metabolism, Transcription Factors/metabolism, Transcription Factors/genetics, DNA-Binding Proteins/metabolism, DNA-Binding Proteins/genetics, Gene Expression Regulation, Neoplastic, Breast Neoplasms, Promoter Regions, Genetic, Biochemistry, Genetics and Molecular Biology (all), Human health sciences, Oncology, Sciences de la santé humaine, Oncologie

Relation: https://api.elsevier.com/content/article/PII:S2211124724013421?httpAccept=text/xml; urn:issn:2211-1247

Prístupová URL adresa: https://orbi.uliege.be/handle/2268/327518

Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation

Autori: Min Ji Cho Dong Gwang Lee Jeong Woong Lee a ďalší

Prispievatelia: Min Ji Cho Dong Gwang Lee Jeong Woong Lee a ďalší

Zdroj: Cardiovascular Research. 119:1265-1278

Predmety: Vasculitis, 0301 basic medicine, Endothelial cells, Inflammation / metabolism, Cell Cycle Proteins / metabolism, Cell Cycle Proteins, Inflammation / genetics, Mice, 03 medical and health sciences, Protein Tyrosine Phosphatases / metabolism, 0302 clinical medicine, Animals, Humans, Vascular inflammation, Inflammation, Cell adhesion molecules, NF-kappa B, Endothelial Cells, Membrane Proteins, Atherosclerosis, Membrane Proteins / metabolism, 3. Good health, Endothelial Cells* / metabolism, NF-kappa B* / metabolism, Protein phosphatase, Upstream Stimulatory Factors / metabolism, Upstream Stimulatory Factors, Protein Tyrosine Phosphatases, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36534975

Intravascular Large B-Cell Lymphoma Genomic Profile Is Characterized by Alterations in Genes Regulating NF-κB and Immune Checkpoints

Autori: Blanca Gonzalez-Farre Joan E. Ramis-Zaldivar Natalia Castrejón de Anta a ďalší

Zdroj: Am J Surg Pathol
The American journal of surgical pathology, vol. 47, no. 2, pp. 202-211

Predmety: 0301 basic medicine, Tumor Suppressor Proteins, NF-kappa B, Original Articles, Genomics, Immune Checkpoint Proteins, B7-H1 Antigen, Lymphohistiocytosis, Hemophagocytic, Immediate-Early Proteins, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Humans, B7-H1 Antigen/genetics, B7-H1 Antigen/metabolism, Immediate-Early Proteins/genetics, Lymphohistiocytosis, Hemophagocytic/genetics, Lymphohistiocytosis, Hemophagocytic/pathology, Lymphoma, Large B-Cell, Diffuse/genetics, Lymphoma, Large B-Cell, Diffuse/pathology, NF-kappa B/genetics, NF-kappa B/metabolism, Tumor Suppressor Proteins/genetics, Immune Checkpoint Proteins/genetics, Immune Checkpoint Proteins/metabolism, Lymphoma, Large B-Cell, Diffuse

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36221796
https://serval.unil.ch/resource/serval:BIB_459C600BD400.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_459C600BD4008
https://serval.unil.ch/notice/serval:BIB_459C600BD400

Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa

Autori: Stamatia Papoutsopoulou Joseph Tang Ahmed H. Elramli a ďalší

Prispievatelia: Stamatia Papoutsopoulou Joseph Tang Ahmed H. Elramli a ďalší

Zdroj: Am J Physiol Gastrointest Liver Physiol
RIULL. Repositorio Institucional de la Universidad de La Laguna
Universidad de La Laguna (ULL)
Papoutsopoulou, S, Tang, J, Elramli, AH, Williams, JM, Gupta, N, Ikuomola, FI, Sheibani-Tezerji, R, Alam, MT, Hernández-Fernaud, JR, Caamano, JH, Probert, CS, Muller, W & Pritchard, DM 2022, 'Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa.', American journal of physiology. Gastrointestinal and liver physiology, vol. 323, no. 4, pp. G306-G317. https://doi.org/10.1152/ajpgi.00037.2022

Predmety: Lipopolysaccharides, Proteomics, 0301 basic medicine, Lydia Becker Institute, Plasma Cells, immunoglobulins, Immunoglobulins, Immunoglobulin A/metabolism, RelB, NF-kappa B p52 Subunit/genetics, plasma cells, NF-κB, Mice, 03 medical and health sciences, Nfkb2, NF-kappa B p52 Subunit, Animals, Intestinal Mucosa, Immunoglobulins/metabolism, 0303 health sciences, Plasma Cells/metabolism, NF-kappa B, Lipopolysaccharides/pharmacology, Immunoglobulin A, 3. Good health, intestinal mucosa, NF-kappa B/metabolism, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, name=Lydia Becker Institute, Intestinal Mucosa/metabolism, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35916405
http://riull.ull.es/xmlui/handle/915/38863

NF-κB Activation and X-Inactivation in Females with Incontinentia Pigmenti and Recurrent Infections

Autori: Laura Krogh Herlin Signe Bech Sørensen Jesper Aagaard Graakjaer a ďalší

Zdroj: Herlin, L K, Sørensen, S B, Graakjaer, J A, Andersen, S, Schmidt, S A J, Sommerlund, M & Mogensen, T H 2024, 'NF-κB Activation and X-Inactivation in Females with Incontinentia Pigmenti and Recurrent Infections', Journal of Clinical Immunology, vol. 44, no. 6, 136, pp. 136. https://doi.org/10.1007/s10875-024-01737-2

Predmety: Incontinentia Pigmenti/genetics, Recurrence, X Chromosome Inactivation, NF-kappa B/metabolism, NF-kappa B, Humans, Female, I-kappa B Kinase/genetics, Incontinentia Pigmenti

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38795145
https://portal.findresearcher.sdu.dk/da/publications/afc72e83-5ff5-4a24-b068-d3ae52c4f816
https://doi.org/10.1007/s10875-024-01737-2
https://pure.au.dk/portal/en/publications/892ae16a-a443-48ca-8511-9eb5842ee840
https://doi.org/10.1007/s10875-024-01737-2
http://www.scopus.com/inward/record.url?scp=85194382015&partnerID=8YFLogxK