Výsledky vyhľadávania - "NAD+ synthase"

Bulk‐ and Surface‐Engineered Carbon Nitride with Promoted Electron Transfer for NADH Regeneration and Artificial Photosynthesis.

Autori: Tao, Chen Wang, Zhuo Dai, Yexin a ďalší

Zdroj: Angewandte Chemie. 8/25/2025, Vol. 137 Issue 35, p1-8. 8p.

Predmety: *ARTIFICIAL photosynthesis, *NAD+ synthase, *CHARGE exchange, *ENZYME inactivation, *GLUTAMIC acid, *RHODIUM compounds, *PHOTOCATALYSTS

Preventive and Protective Effects of Nicotinamide Adenine Dinucleotide Boosters in Aging and Retinal Diseases.

Autori: Noreen, Saba Lim, Soon Sung Lee, Deokho

Zdroj: International Journal of Molecular Sciences; Nov2025, Vol. 26 Issue 22, p10923, 15p

Predmety: NAD (Coenzyme), RETINAL diseases, MITOCHONDRIAL pathology, NAD+ synthase, MACULAR degeneration, BIOACTIVE compounds, OXIDATIVE stress, DIABETIC retinopathy

A photosensitive conjugated pyromellitic-based covalent organic framework composite for visible-light-driven NADPH cofactor regeneration and aerobic oxidation in green photocatalytic applications.

Autori: Rai, Anurag Yadav, Rajesh K. Gole, Vitthal L. a ďalší

Zdroj: New Journal of Chemistry; 11/7/2025, Vol. 49 Issue 41, p17951-17958, 8p

Predmety: PHOTOCATALYSTS, SUSTAINABLE chemistry, POLYMER networks, NAD+ synthase, PHYSIOLOGICAL oxidation, SOLAR energy, PHOTOSENSITIVITY

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS.

Autori: Nuyttens, Louise Heyerick, Marah Roes, Maxime a ďalší

Zdroj: Frontiers in Immunology; 2025, p1-18, 18p

Predmety: SYSTEMIC inflammatory response syndrome, METABOLIC reprogramming, HYPERLACTATEMIA, TUMOR necrosis factors, NAD+ synthase, GLYCOLYSIS, DRUG target

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1.

Autori: Ranieri, Giuseppe Lapucci, Andrea Orsomando, Giuseppe a ďalší

Zdroj: FEBS Letters; Nov2025, Vol. 599 Issue 21, p3150-3162, 13p

Predmety: CELL death, PHARMACOLOGY, TUMORS, NAD+ synthase, ANTIMETABOLITES, ANTINEOPLASTIC agents

Altered nicotinamide adenine dinucleotide metabolism drives cartilage degeneration and osteoarthritis.

Autori: Wu, Xiaoxin Fan, Xiwei Plan, Manuel a ďalší

Zdroj: Clinical & Translational Medicine; Nov2025, Vol. 15 Issue 11, p1-17, 17p

Predmety: OSTEOARTHRITIS, POLY(ADP-ribose) polymerase, ENERGY metabolism, CARTILAGE diseases, NAD+ synthase

Vascular Endothelial NAMPT‐Mediated NAD⁺ Biosynthesis Regulates Angiogenesis and Cardiometabolic Functions in Male Mice.

Autori: Kosugi, Shotaro Yamaguchi, Shintaro Nishioka, Ken a ďalší

Zdroj: Aging Cell; Nov2025, Vol. 24 Issue 11, p1-18, 18p

Predmety: AGING, VASCULAR endothelial cells, SIRTUINS, ENERGY metabolism, NAD+ synthase, NEOVASCULARIZATION, NITRIC oxide regulation, ENZYME metabolism

Inhibition of CD38 enzyme activity on engrafted human immune cells enhances NAD+ metabolism and inhibits inflammation in an in-vivo model of xeno-GvHD.

Autori: Ahmil-Boiteau, Ghenima Dalvi, Pranjali Dang, Kevin a ďalší

Zdroj: Frontiers in Immunology; 2025, p1-18, 18p

Predmety: INFLAMMATION, THERAPEUTICS, IMMUNOREGULATION, LEUKOCYTES, GRAFT versus host disease, CD38 antigen, REGULATORY T cells, NAD+ synthase

Highly selective 1,4-NADH regeneration via hydrogenated NAD⁺ analogs using a Pt/SiO2 catalyst with low pressure hydrogen gas.

Autori: Hirano, Makoto Onodera, Wataru Tamura, Masazumi a ďalší

Zdroj: Chemical Communications; 10/25/2025, Vol. 61 Issue 83, p16186-16189, 4p

Predmety: HYDROGENATION, NICOTINAMIDE, HYDROGEN, ABSTRACTION reactions, NAD+ synthase, PLATINUM catalysts

Microfluidic‐Assisted Evolution of a Robust NAD⁺‐Dependent Enzyme with Improved Isobutanol Tolerance at Elevated Temperatures.

Autori: Teshima, Mariko Genth, Robert Bayaraa, Tenuun a ďalší

Zdroj: ChemSusChem; 10/23/2025, Vol. 18 Issue 20, p1-14, 14p

Predmety: THERMAL stability, PROTEIN engineering, MULTIENZYME complexes, BIOSYNTHESIS, NAD+ synthase, MICROFLUIDICS, ENZYME biotechnology

Systemic nicotinamide mononucleotide administration to mitigate post-cardiac arrest brain injury in mice.

Autori: Kaito, Daiki Tamura, Tomoyoshi Suzuki, Sayuri a ďalší

Zdroj: PLoS ONE; 10/21/2025, Vol. 20 Issue 10, p1-15, 15p

Predmety: NAD (Coenzyme), SIRTUINS, NEUROPHYSIOLOGY, MITOCHONDRIA, SURVIVAL rate, BRAIN injuries, NAD+ synthase, NEUROPROTECTIVE agents

Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment.

Autori: D'Alessandro, Karis B. Zampese, Enrico Blum, Jenna L. E. a ďalší

Zdroj: Frontiers in Cell & Developmental Biology; 2025, p1-11, 11p

Predmety: DOPAMINERGIC neurons, PARKINSON'S disease, PSYCHOMOTOR disorders, NEURODEGENERATION, NADH dehydrogenase, NAD+ synthase

Progress in understanding how clock genes regulate aging and associated metabolic processes.

Autori: Su, Yanhong Wang, Meng Chen, Juan a ďalší

Zdroj: Frontiers in Physiology; 2025, p1-21, 21p

Predmety: CIRCADIAN rhythms, CLOCK genes, METABOLIC disorders, HOMEOSTASIS, NAD+ synthase, SIRTUINS, AGING, GENETIC transcription regulation

Harmonizing NAD⁺ metabolism with CeMOF nanozyme to orchestrate intraocular pressure modulation for glaucoma treatment.

Autori: Zhang, Youjia Chen, Ming Tian, Yi a ďalší

Zdroj: View (2688-268X); Oct2025, Vol. 6 Issue 5, p1-18, 18p

Predmety: GLAUCOMA, INTRAOCULAR pressure, NANOPARTICLES, OXIDATIVE stress, THERAPEUTICS, NICOTINAMIDE, NAD+ synthase

Intermedin Inhibits DNA Damage-Promoted Senescent Phenotype Transition of Vascular Smooth Muscle Cells in Aorta by Activating NAMPT/PARP1 in Mice.

Autori: Ji, Deng-Ren Chen, Yao Zhu, Han-Xu a ďalší

Zdroj: Pharmaceuticals (14248247); Oct2025, Vol. 18 Issue 10, p1503, 19p

Predmety: DNA damage, POLY(ADP-ribose) polymerase, VASCULAR smooth muscle, PEPTIDES, NAD+ synthase, AGING, CARDIOVASCULAR diseases, AORTA

Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy.

Autori: Delrue, Charlotte Speeckaert, Reinhart Speeckaert, Marijn M.

Zdroj: International Journal of Molecular Sciences; Oct2025, Vol. 26 Issue 19, p9372, 25p

Predmety: AGING, PHARMACOLOGY, DRUG therapy, LONGEVITY, METABOLIC regulation, MTOR inhibitors, CLINICAL trials, NAD+ synthase

Jianpi‐Huogu Prescription Repairs Nontraumatic Osteonecrosis of the Femoral Head by Inhibiting NAMPT/STK11/HMGCR/ACAT1 Axis‐Mediated Lipid Production.

Autori: Li, Tao Ma, Zhaochen Gao, Shuangrong a ďalší

Zdroj: Journal of Cellular & Molecular Medicine; Sep2025, Vol. 29 Issue 18, p1-14, 14p

Predmety: LIPID metabolism, CHOLESTEROL metabolism, FEMUR head, OSTEONECROSIS, BONE health, CHINESE medicine, NAD+ synthase

The Roles of Moonlighting Nicotinamide Mononucleotide Adenylyl Transferases in Cell Physiology.

Autori: Lee, Yi-Ching Lin, Su-Ju

Zdroj: International Journal of Molecular Sciences; Sep2025, Vol. 26 Issue 18, p9098, 26p

Predmety: NAD (Coenzyme), CELL physiology, DRUG target, NEUROPROTECTIVE agents, NAD+ synthase

Interferon-induced senescent CD8⁺ T cells reduce anti-PD1 immunotherapy efficacy in early triple-negative breast cancer.

Autori: Fu, Tong Jin, Xi He, Min a ďalší

Zdroj: Science Translational Medicine; 9/10/2025, Vol. 17 Issue 815, p1-16, 16p

Predmety: INTERFERONS, IMMUNOTHERAPY, NAD+ synthase, TRIPLE-negative breast cancer, AGING, PROGRAMMED cell death 1 receptors, T-cell exhaustion, TUMOR treatment

β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD⁺/SIRT1 signaling pathways.

Autori: Yang, Xinxin Zheng, Endian Lin, Yuxian a ďalší

Zdroj: Hereditas; 8/16/2025, Vol. 162 Issue 1, p1-13, 13p

Predmety: NAD (Coenzyme), ALCOHOLIC liver diseases, NAD+ synthase, SIRTUINS, ANTIOXIDANTS, INTESTINAL barrier function, LABORATORY mice, ANTI-inflammatory agents