Search Results - "Myeloid-Derived Suppressor Cells pathology"

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

Authors: Matthias Gunzer Maciej Lech Philipp Metzger et al.

Source: Cancer Immunol Immunother
Cancer Immunol. Immunother. 69, 2101–2112 (2020)

Subject Terms: Immunosuppression Therapy, Mice, Knockout, 0301 basic medicine, 0303 health sciences, Myeloid-Derived Suppressor Cells, Medizin, Apoptosis, CD8-Positive T-Lymphocytes, Prognosis, 3. Good health, Pancreatic Neoplasms, Survival Rate, Disease Models, Animal, Mice, 03 medical and health sciences, Immunosuppression [MeSH], Myeloid-Derived Suppressor Cells/immunology [MeSH], Pancreatic Neoplasms/pathology [MeSH], Myeloid-Derived Suppressor Cells/metabolism [MeSH], Apoptosis [MeSH], Tumor Microenvironment/immunology [MeSH], Myeloid-Derived Suppressor Cells/pathology [MeSH], Original Article, Tumor Cells, Cultured [MeSH], CD8-Positive T-Lymphocytes/pathology [MeSH], Biomarkers, Tumor/analysis [MeSH], CD8-Positive T-Lymphocytes/immunology [MeSH], Myeloid-derived suppressor cells (MDSC), Disease Models, Animal [MeSH], Myelopoiesis, Pancreatic cancer, CD8-Positive T-Lymphocytes/metabolism [MeSH], Cell Proliferation [MeSH], Humans [MeSH], IRF4, Immunosuppression, Animals [MeSH], Mice, Knockout [MeSH], Survival Rate [MeSH], Pancreatic Neoplasms/immunology [MeSH], Mice [MeSH], Interferon Regulatory Factors/physiology [MeSH], Prognosis [MeSH], Pancreatic Neoplasms/metabolism [MeSH], Interferon Regulatory Factors, Biomarkers, Tumor, Tumor Cells, Cultured, Tumor Microenvironment, Myeloid-derived Suppressor Cells (mdsc), Irf4, Pancreatic Cancer, Animals, Humans, Cell Proliferation

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Access URL: https://link.springer.com/content/pdf/10.1007/s00262-020-02605-9.pdf
https://pubmed.ncbi.nlm.nih.gov/32448983
https://link.springer.com/article/10.1007/s00262-020-02605-9
https://www.ncbi.nlm.nih.gov/pubmed/32448983
https://pubmed.ncbi.nlm.nih.gov/32448983/
https://epub.ub.uni-muenchen.de/73123/
https://link.springer.com/content/pdf/10.1007/s00262-020-02605-9.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511276
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59201
https://repository.publisso.de/resource/frl:6470062
https://epub.ub.uni-muenchen.de/73123/
https://www.ncbi.nlm.nih.gov/pubmed/32448983
https://doi.org/10.1007/s00262-020-02605-9
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85085335661