Search Results - "Molecular subtyping"

Cancer biomarkers: Molecular insights and implications for targeted therapy

Authors: Anura, Fatimah Aminat, Anura Ubhenin, Abraham Ehinomhen et al.

Source: Sokoto Journal of Medical Laboratory Science; Vol. 10 No. 1 (2025); 271-288

Subject Terms: Breast Cancer, Cancer Biomarkers, Personalized Therapy, Molecular Subtyping, Targeted Treatment, HER2 Inhibitors, Liquid Biopsies

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Access URL: https://www.ajol.info/index.php/sokjmls/article/view/298102

Deciphering riddles in molecular subtyping of bladder cancer

Authors: Yuxiao Li Suyuelin Huang Wenlong Ju et al.

Source: Asian J Urol
Asian Journal of Urology, Vol 12, Iss 2, Pp 217-231 (2025)

Subject Terms: Targeted therapy, Neoadjuvant immunotherapy, Bladder cancer, RC870-923, Review, Molecular subtyping, Neoadjuvant chemotherapy, Diseases of the genitourinary system. Urology

Access URL: https://doaj.org/article/3bf34f3973724097b9037b095c4801f2

Overcoming CAR-T bottlenecks in high-risk DLBCL: a molecular subtyping enhancement strategy

Authors: Rubing Zheng Xiaojian Zhu Yi Xiao

Source: Cancer Cell International, Vol 25, Iss 1, Pp 1-22 (2025)

Subject Terms: DLBCL, Molecular subtyping, Drug resistance mechanisms, CAR-T, Molecular targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

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Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/3ba556b446834def94a277654d29f479

Clinical-grade AI model for molecular subtyping of endometrial cancer: a multi-center cohort study in China

Authors: Peng Qi Tianliang Yao Hu Li et al.

Source: Molecular Biomedicine, Vol 6, Iss 1, Pp 1-15 (2025)

Subject Terms: Endometrial cancer, Molecular subtyping, Whole slide imaging, Deep learning, Artificial intelligence, Digital pathology, Medicine

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Relation: https://doaj.org/toc/2662-8651

Access URL: https://doaj.org/article/faf50906ac5d40f382b98afbbb4e8761

Gliomas Analysis via Multimodal MRI-Deep Learning Fusion: Technical Innovations in Segmentation, Molecular Subtyping, and Clinical Translation Pathways

Authors: Yi G Ma W Yu Z et al.

Source: Advances in Medical Education and Practice, Vol 16, Iss Issue 1, Pp 1989-2001 (2025)

Subject Terms: Glioblastoma, Multimodal MRI, Deep Learning, Radiomics, Molecular Subtyping, Anatomical-Molecular Co-Optimization, Special aspects of education, LC8-6691, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/gliomas-analysis-via-multimodal-mri-deep-learning-fusion-technical-inn-peer-reviewed-fulltext-article-AMEP; https://doaj.org/toc/1179-7258

Access URL: https://doaj.org/article/9fb7d6ad54554eb8be10d857e180709c

BreastSubtypeR: Assumption-aware intrinsic molecular subtyping for breast cancer research

Authors: Yang, Qiao Hartman, Johan Sifakis, Emmanouil

Subject Terms: FOS: Computer and information sciences, Breast cancer, Bioinformatics, EuroBioC2025, Bioconductor, Intrinsic Molecular Subtyping, Reproducibility of Results

Molecular Subtyping for Predicting Pathological Upstaging and Survival Outcomes in Clinically Organ-confined Bladder Cancer Patients Undergoing Radical Cystectomy

Authors: de Jong, Joep J. Proudfoot, James A. Daneshmand, Siamak et al.

Source: Eur Urol Open Sci
European Urology Open Science, Vol 73, Iss, Pp 24-30 (2025)

Subject Terms: Radical cystectomy, SDG 3 - Good Health and Well-being, Clinical staging, Bladder cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC870-923, Molecular subtyping, Bladder Cancer, Diseases of the genitourinary system. Urology, RC254-282

Access URL: https://pubmed.ncbi.nlm.nih.gov/39935941
https://doaj.org/article/d707ec17595e4857aa366368e959f576
https://pure.eur.nl/en/publications/dc86bcf8-26e4-4cba-8642-2cb365cecfd6
https://doi.org/10.1016/j.euros.2024.12.009

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Authors: Rita Pinto Hege Marie Vedeld Guro Elisabeth Lind et al.

Source: Mol Oncol
Molecular Oncology, Vol 19, Iss 4, Pp 1117-1131 (2025)

Subject Terms: 0301 basic medicine, molecular subtyping, 0303 health sciences, 03 medical and health sciences, DNA methylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, differential variability, RC254-282, Research Article

Access URL: https://pubmed.ncbi.nlm.nih.gov/39696831
https://doaj.org/article/1a3ffd0574af41ee9b519c2a20dd30f5

Methods in DNA methylation array dataset analysis: A review

Authors: Karishma Sahoo Vino Sundararajan

Source: Comput Struct Biotechnol J
Computational and Structural Biotechnology Journal, Vol 23, Iss, Pp 2304-2325 (2024)

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Prognostic models, Review Article, Biomarker identification, DMR analysis, Molecular subtyping, Methylation segmentation, Clustering, TP248.13-248.65, Biotechnology

Access URL: https://pubmed.ncbi.nlm.nih.gov/38845821
https://doaj.org/article/bab088daf67643e3a1fe56dd8c8979f2

NK cell-associated long non-coding RNAs reveal heterogeneity of colorectal cancer immune microenvironment

Authors: Yuxuan Li Chuqi Xia Jinze Li et al.

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: tumor immune single-cell hub 2, colorectal cancer, NK cell-related lncRNAs, tumor immune microenvironment, molecular subtyping, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1615942/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/665c028147c446a9a1f0eefb152e0838

Federated radiomics analysis of preoperative MRI across institutions: toward integrated glioma segmentation and molecular subtyping

Authors: Ran Ren Anjun Zhu Yaxi Li et al.

Source: Frontiers in Radiology, Vol 5 (2025)

Subject Terms: federated learning, multi-institutional, multi-task deep learning model, molecular subtyping, image segmentation, Medical physics. Medical radiology. Nuclear medicine, R895-920

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Relation: https://www.frontiersin.org/articles/10.3389/fradi.2025.1648145/full; https://doaj.org/toc/2673-8740

Access URL: https://doaj.org/article/6bc8123eda784aaf88b222eaab5585de

Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC

Authors: Qianqian Zhang Guoxin Wang Wenjie Yan et al.

Source: Cancer Immunology, Immunotherapy, Vol 74, Iss 7, Pp 1-15 (2025)

Subject Terms: ES-SCLC, Molecular subtyping, NE differentiation, TME, Immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/1432-0851

Access URL: https://doaj.org/article/cd3d351de41e4e2d9466e0efa438ed21

Combining multi-omics analysis with machine learning to uncover novel molecular subtypes, prognostic markers, and insights into immunotherapy for melanoma

Authors: Songyun Zhao Zihao Li Kaibo Liu et al.

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-21 (2025)

Subject Terms: Melanoma, Multi-omics analysis, Machine learning, Molecular subtyping, MLDS, AGPAT2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/53c133f75d484a8480a5da5b375fa1e2

Comprehensive analyses of nuclear mitochondria‐related genes in the molecular features, immune infiltration, and drug sensitivity of clear cell renal cell carcinoma

Authors: Yuchen Zhang Huake Cao Feixiang Yang et al.

Source: Medicine Advances, Vol 2, Iss 3, Pp 238-253 (2024)

Subject Terms: molecular subtyping, nuclear mitochondria‐related genes, immune characteristics, Medicine, clear cell renal cell carcinoma, drug sensitivity

Access URL: https://doaj.org/article/bfddb24263a54a07ac729746ef20bd1c

Immunohistochemical Breast Cancer Profiling Among Iraqi Women: Molecular Subtype Classification, Clinicopathology Associations, and Treatment‐Decision Making Tools: A Cross‐Sectional Study

Authors: Alaa Salah Jumaah Roaa Ali Shaker Zainab Al‐Ali et al.

Source: Health Sci Rep
Health Science Reports, Vol 8, Iss 5, Pp n/a-n/a (2025)

Subject Terms: molecular subtyping, breast cancer, immunohistochemistry, clinicopathology, Medicine, survival, Original Research

Access URL: https://pubmed.ncbi.nlm.nih.gov/40391262
https://doaj.org/article/cc76390e5dac4ddba759f3abc96c5ca4

Cancer Biomarkers: Molecular Insights and Implications for Targeted Therapy

Authors: Fatimah Anura*1, Anura Aminat 2, Abraham Ehinomhen Ubhenin1, Ramatu Iya Idris 1, Yusuf Nafisat Abdulmalik 3, Jammy Peters Mairiga4

Source: Sokoto Journal of Medical Laboratory Science, Vol 10, Iss 1 (2025)

Subject Terms: RC86-88.9, Medical emergencies. Critical care. Intensive care. First aid, breast cancer, cancer biomarkers, personalized therapy, molecular subtyping, targeted treatment, her2 inhibitors, liquid biopsies

Access URL: https://doaj.org/article/6b2bd0b308dd45c294915df125561c90

Building flexible and robust analysis frameworks for molecular subtyping of cancers

Authors: Christina Bligaard Pedersen Benito Campos Lasse Rene et al.

Source: Mol Oncol
Molecular Oncology, Vol 18, Iss 3, Pp 606-619 (2024)
Pedersen, C B, Campos, B, Rene, L, Wegener, H S, Krishnan, N M, Panda, B, Vitting-Seerup, K, Rossing, M, Bagger, F O & Olsen, L R 2024, ' Building flexible and robust analysis frameworks for molecular subtyping of cancers ', Molecular Oncology, vol. 18, no. 3, pp. 606-619 . https://doi.org/10.1002/1878-0261.13580

Subject Terms: 0301 basic medicine, 0303 health sciences, Gene Expression Profiling, Sample classification, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Computational Biology, sample classification, Breast Neoplasms, bioinformatics workflows, Clinical bioinformatics, 3. Good health, Gene Expression Regulation, Neoplastic, molecular subtyping, 03 medical and health sciences, Bioinformatics workflows, Humans, RNA, Female, name=SDG 3 - Good Health and Well-being, Molecular subtyping, clinical bioinformatics, RC254-282, Research Articles

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Access URL: https://pubmed.ncbi.nlm.nih.gov/38158740
https://doaj.org/article/91af8075ca0347618bf363e33adca13d
https://orbit.dtu.dk/en/publications/26c5857a-2c8c-46d1-aec5-bd093285566b

Protein phosphorylation regulation of key genes in oral squamous cell carcinoma and their role in the immune microenvironment

Authors: Yu Zeng Chunyang Wang Wenli Zhao et al.

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: oral squamous cell carcinoma, FN1, multi-omics analysis, immune microenvironment, molecular subtyping, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1677807/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8484da6fbb2140e3a760170d743be440

NK cell-related genes-driven novel molecular subtyping and prognostic signatures for Wilms tumor: uncovering the therapeutic potential of TGX-221 and biomarker role of HS2ST1

Authors: Peng Hong Zaihong Hu Jie Lin et al.

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: Wilms tumor, natural killer cells, molecular subtyping, prognostic signatures, TGX-221, HS2ST1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1593011/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/cd4050a3d6a74de7b312fcc2fa77daa9

Immunoproteasome subunits are novel signatures for predicting efficacy of immunotherapy in muscle invasive bladder cancer

Authors: XinJian Wang Hang You Teng Zhang et al.

Source: Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-16 (2025)

Subject Terms: Muscle invasive bladder cancer, Immunoproteasome, Molecular subtyping, Immune checkpoint, Immunotherapy, Medicine

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Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/60d6b79c5d6b4eea8c7a2a407d24fb82