Search Results - "Models, Cardiovascular"

Systematic computational assessment of atrial function impairment due to fibrotic remodeling in electromechanical properties.

Authors: Telle Å Kassar A Chamoun N et al.

Source: PLoS computational biology [PLoS Comput Biol] 2025 Dec 05; Vol. 21 (12), pp. e1013265. Date of Electronic Publication: 2025 Dec 05 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH Terms: Heart Atria*/physiopathology , Heart Atria*/pathology , Models, Cardiovascular* , Atrial Remodeling*/physiology , Atrial Function*/physiology, Humans ; Fibrosis/physiopathology ; Computational Biology ; Computer Simulation

Strategies for prolonging ventricular action potential duration without increasing transmural dispersion of repolarization.

Authors: Cabo C; Department of Computer Systems, New York City College of Technology, New York, New York, USA.; Graduate Center, City University of New York, New York, New York, USA.

Source: Physiological reports [Physiol Rep] 2025 Dec; Vol. 13 (23), pp. e70693.

Publication Type: Journal Article

Journal Info: Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE

MeSH Terms: Action Potentials*/drug effects , Action Potentials*/physiology , Models, Cardiovascular* , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/physiology , Anti-Arrhythmia Agents*/pharmacology, Humans ; Ion Channels/metabolism ; Computer Simulation ; Heart Ventricles/drug effects ; Arrhythmias, Cardiac/physiopathology

Newly Proposed Method With Noise-Reduction and Smoothing for Computational Fluid Dynamics Using Low-Resolution Medical Images.

Authors: Yanagita Y Abhilash HN Khader SMA et al.

Source: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2025 Dec; Vol. 41 (12), pp. e70125.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101530293 Publication Model: Print Cited Medium: Internet ISSN: 2040-7947 (Electronic) Linking ISSN: 20407939 NLM ISO Abbreviation: Int J Numer Method Biomed Eng Subsets: MEDLINE

MeSH Terms: Hydrodynamics* , Image Processing, Computer-Assisted*/methods , Models, Cardiovascular*, Humans ; Carotid Arteries/physiology ; Stress, Mechanical ; Computer Simulation ; Algorithms ; Cerebral Arteries/physiology

A Fluid-Structure Interaction Computational Study of Residual Aortic Dissection to Investigate the Influence of Mechanical Behaviour of Wall and Flap on Flows.

Authors: Guivier-Curien C Deplano V

Source: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2025 Dec; Vol. 41 (12), pp. e70120.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101530293 Publication Model: Print Cited Medium: Internet ISSN: 2040-7947 (Electronic) Linking ISSN: 20407939 NLM ISO Abbreviation: Int J Numer Method Biomed Eng Subsets: MEDLINE

MeSH Terms: Aortic Dissection*/physiopathology , Models, Cardiovascular*, Humans ; Computer Simulation ; Stress, Mechanical ; Biomechanical Phenomena ; Elastic Modulus

A minimal electrical model of the human heart.

Authors: Olívia J Dilão R

Source: Chaos (Woodbury, N.Y.) [Chaos] 2025 Dec 01; Vol. 35 (12).

Publication Type: Journal Article

Journal Info: Publisher: American Institute of Physics Country of Publication: United States NLM ID: 100971574 Publication Model: Print Cited Medium: Internet ISSN: 1089-7682 (Electronic) Linking ISSN: 10541500 NLM ISO Abbreviation: Chaos Subsets: MEDLINE

MeSH Terms: Models, Cardiovascular* , Heart Conduction System*/physiopathology , Heart Conduction System*/physiology , Heart*/physiology, Humans ; Electrocardiography ; Arrhythmias, Cardiac/physiopathology ; Computer Simulation

Coupling Models of Resistive Valves to Muscle Mechanics in Cardiac Fluid-Structure Interaction Simulations.

Authors: Bucelli M Dede L

Source: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2025 Dec; Vol. 41 (12), pp. e70119.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101530293 Publication Model: Print Cited Medium: Internet ISSN: 2040-7947 (Electronic) Linking ISSN: 20407939 NLM ISO Abbreviation: Int J Numer Method Biomed Eng Subsets: MEDLINE

MeSH Terms: Models, Cardiovascular* , Heart Valves*/physiology, Humans ; Computer Simulation ; Hemodynamics/physiology ; Biomechanical Phenomena

Computational Framework for Modeling Effects of Brain Collateral Circulation.

Authors: Mut F Lohner R Pradhan A et al.

Source: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2025 Dec; Vol. 41 (12), pp. e70121.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 101530293 Publication Model: Print Cited Medium: Internet ISSN: 2040-7947 (Electronic) Linking ISSN: 20407939 NLM ISO Abbreviation: Int J Numer Method Biomed Eng Subsets: MEDLINE

MeSH Terms: Collateral Circulation*/physiology , Cerebrovascular Circulation*/physiology , Brain*/blood supply , Brain*/physiology , Computer Simulation* , Models, Cardiovascular*, Humans ; Circle of Willis/physiology

ZEUS: Numerical methods to detect quasi-particles describing excitable media.

Authors: Gobeyn A Kabus D Tolkacheva EG et al.

Source: Chaos (Woodbury, N.Y.) [Chaos] 2025 Dec 01; Vol. 35 (12).

Publication Type: Journal Article

Journal Info: Publisher: American Institute of Physics Country of Publication: United States NLM ID: 100971574 Publication Model: Print Cited Medium: Internet ISSN: 1089-7682 (Electronic) Linking ISSN: 10541500 NLM ISO Abbreviation: Chaos Subsets: MEDLINE

MeSH Terms: Algorithms* , Models, Cardiovascular* , Action Potentials* , Heart Conduction System*/physiopathology , Nonlinear Dynamics*, Animals ; Rabbits ; Computer Simulation ; Tachycardia, Ventricular/physiopathology

Discovering dispersion: How robust is automated model discovery for human myocardial tissue?

Authors: Martonová D Leyendecker S Holzapfel GA et al.

Source: Biomechanics and modeling in mechanobiology [Biomech Model Mechanobiol] 2025 Dec; Vol. 24 (6), pp. 2023-2037. Date of Electronic Publication: 2025 Aug 27.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101135325 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-7940 (Electronic) Linking ISSN: 16177940 NLM ISO Abbreviation: Biomech Model Mechanobiol Subsets: MEDLINE

MeSH Terms: Myocardium*/cytology , Models, Cardiovascular* , Heart*/physiology, Humans ; Automation ; Stress, Mechanical ; Biomechanical Phenomena ; Computer Simulation ; Anisotropy

A hybrid reduced order model to enforce outflow pressure boundary conditions in computational hemodynamics.

Authors: Siena P Africa PC Girfoglio M et al.

Source: Biomechanics and modeling in mechanobiology [Biomech Model Mechanobiol] 2025 Dec; Vol. 24 (6), pp. 2069-2093. Date of Electronic Publication: 2025 Sep 15.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101135325 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-7940 (Electronic) Linking ISSN: 16177940 NLM ISO Abbreviation: Biomech Model Mechanobiol Subsets: MEDLINE

MeSH Terms: Hemodynamics*/physiology , Models, Cardiovascular* , Computer Simulation* , Pressure*, Humans ; Blood Flow Velocity/physiology ; Blood Pressure ; Finite Element Analysis

A computational model-based study on the mechano-energetic characteristics of the left ventricle with obstructive hypertrophic cardiomyopathy before and after septal myectomy.

Authors: Liu T Zhou M Qin L et al.

Source: Biomechanics and modeling in mechanobiology [Biomech Model Mechanobiol] 2025 Dec; Vol. 24 (6), pp. 1973-2001. Date of Electronic Publication: 2025 Sep 05.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101135325 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-7940 (Electronic) Linking ISSN: 16177940 NLM ISO Abbreviation: Biomech Model Mechanobiol Subsets: MEDLINE

MeSH Terms: Cardiomyopathy, Hypertrophic*/physiopathology , Cardiomyopathy, Hypertrophic*/surgery , Heart Ventricles*/physiopathology , Heart Ventricles*/pathology , Heart Ventricles*/surgery , Computer Simulation* , Heart Septum*/surgery , Heart Septum*/physiopathology , Models, Cardiovascular*, Humans ; Finite Element Analysis ; Biomechanical Phenomena ; Stress, Mechanical ; Male ; Middle Aged ; Ventricular Outflow Obstruction/physiopathology

Making the invisible visible: exploring cardiovascular regulation with a simple analog blood pressure model.

Authors: Lujan HL DiCarlo SE

Source: Advances in physiology education [Adv Physiol Educ] 2025 Dec 01; Vol. 49 (4), pp. 899-908. Date of Electronic Publication: 2025 Aug 12.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100913944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1229 (Electronic) Linking ISSN: 10434046 NLM ISO Abbreviation: Adv Physiol Educ Subsets: MEDLINE

MeSH Terms: Blood Pressure*/physiology , Models, Cardiovascular* , Physiology*/education, Humans ; Heart Rate/physiology

Comparison of Hemodynamic Circulation in Pulsatile and Nonpulsatile Extracorporeal Membrane Oxygenation Systems Using an In-Vitro Heart Model.

Authors: Yoo C Jang HW Kang S et al.

Source: ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2025 Dec 01; Vol. 71 (12), pp. 998-1005. Date of Electronic Publication: 2025 Apr 17.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9204109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-943X (Electronic) Linking ISSN: 10582916 NLM ISO Abbreviation: ASAIO J Subsets: MEDLINE

MeSH Terms: Extracorporeal Membrane Oxygenation*/methods , Extracorporeal Membrane Oxygenation*/instrumentation , Pulsatile Flow*/physiology , Hemodynamics*/physiology , Models, Cardiovascular* , Heart*/physiology, Humans ; Shock, Cardiogenic/therapy ; Shock, Cardiogenic/physiopathology

Inverse analysis of patient-specific parameters of a 3D-0D closed-loop cardiovascular model with an exemplary application to an adult tetralogy of Fallot case.

Authors: Arjoune T Bilas C Meierhofer C et al.

Source: Biomechanics and modeling in mechanobiology [Biomech Model Mechanobiol] 2025 Dec; Vol. 24 (6), pp. 2039-2068. Date of Electronic Publication: 2025 Sep 13.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101135325 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-7940 (Electronic) Linking ISSN: 16177940 NLM ISO Abbreviation: Biomech Model Mechanobiol Subsets: MEDLINE

MeSH Terms: Tetralogy of Fallot*/physiopathology , Tetralogy of Fallot*/diagnostic imaging , Models, Cardiovascular* , Imaging, Three-Dimensional* , Patient-Specific Modeling*, Humans ; Adult ; Algorithms ; Computer Simulation

A two-phase model of early atherosclerotic plaque development with LDL toxicity effects.

Authors: Pramanik AS Dey B Sekhar GPR

Source: Mathematical biosciences [Math Biosci] 2025 Dec; Vol. 390, pp. 109547. Date of Electronic Publication: 2025 Oct 06.

Publication Type: Journal Article

Journal Info: Publisher: American Elsevier Country of Publication: United States NLM ID: 0103146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3134 (Electronic) Linking ISSN: 00255564 NLM ISO Abbreviation: Math Biosci Subsets: MEDLINE

MeSH Terms: Lipoproteins, LDL*/toxicity , Lipoproteins, LDL*/metabolism , Plaque, Atherosclerotic*/pathology , Plaque, Atherosclerotic*/metabolism , Models, Cardiovascular* , Atherosclerosis*/pathology, Humans ; Foam Cells/metabolism ; Cholesterol/metabolism ; Macrophages ; Cytokines/metabolism

A probabilistic modeling framework for the prediction of spontaneous premature beats and reentry initiation.

Authors: Gray RA; Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland. Electronic address: richard.gray@fda.hhs.gov.

Source: Heart rhythm [Heart Rhythm] 2025 Dec; Vol. 22 (12), pp. 3268-3276. Date of Electronic Publication: 2025 Jan 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101200317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-3871 (Electronic) Linking ISSN: 15475271 NLM ISO Abbreviation: Heart Rhythm Subsets: MEDLINE

MeSH Terms: Heart Conduction System*/physiopathology , Models, Statistical* , Models, Cardiovascular* , Cardiac Complexes, Premature*/physiopathology, Rabbits ; Animals ; Action Potentials/physiology ; Arrhythmias, Cardiac/physiopathology ; Ventricular Premature Complexes/physiopathology

Analytical Insights into Ephaptic Coupling and Its Effect on Conduction Velocity.

Authors: Wei N Mori Y

Source: Journal of mathematical biology [J Math Biol] 2025 Nov 25; Vol. 91 (6), pp. 85. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7502105 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1416 (Electronic) Linking ISSN: 03036812 NLM ISO Abbreviation: J Math Biol Subsets: MEDLINE

MeSH Terms: Heart Conduction System*/physiology , Heart Conduction System*/physiopathology , Models, Cardiovascular*, Animals ; Gap Junctions/physiology ; Action Potentials/physiology ; Arrhythmias, Cardiac/physiopathology ; Arrhythmias, Cardiac/etiology ; Humans ; Mice ; Cell Communication/physiology ; Myocytes, Cardiac/physiology ; Mathematical Concepts ; Computer Simulation ; Mice, Knockout

Invasive validation of novel 1D models for computation of coronary fractional flow reserve.

Authors: Taylor DJ Saxton H Xu X et al.

Source: Cardiovascular research [Cardiovasc Res] 2025 Nov 22; Vol. 121 (14), pp. 2233-2245.

Publication Type: Journal Article; Validation Study; Comparative Study

Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

MeSH Terms: Fractional Flow Reserve, Myocardial* , Models, Cardiovascular* , Coronary Vessels*/physiopathology , Coronary Vessels*/diagnostic imaging , Coronary Angiography*/methods , Coronary Artery Disease*/physiopathology , Coronary Artery Disease*/diagnostic imaging , Cardiac Catheterization* , Coronary Stenosis*/physiopathology , Coronary Stenosis*/diagnostic imaging, Humans ; Predictive Value of Tests ; Reproducibility of Results ; Male ; Female ; Middle Aged ; Aged ; Computer Simulation

Biphasic effects on human atrial arrhythmogenicity of L-type calcium channel mutations associated with a Brugada/Short QT overlap syndrome - insights from a multiscale simulation study.

Authors: Xiang Y Hancox JC Zhang H

Source: PLoS computational biology [PLoS Comput Biol] 2025 Nov 19; Vol. 21 (11), pp. e1013616. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH Terms: Calcium Channels, L-Type*/genetics , Brugada Syndrome*/genetics , Brugada Syndrome*/physiopathology , Arrhythmias, Cardiac*/genetics , Arrhythmias, Cardiac*/physiopathology , Models, Cardiovascular* , Syndactyly*/genetics , Syndactyly*/physiopathology, Humans ; Heart Atria/physiopathology ; Computer Simulation ; Computational Biology ; Mutation, Missense ; Mutation ; Action Potentials ; Atrial Fibrillation/genetics ; Atrial Fibrillation/physiopathology

SCR Disease Name: Short Qt Syndrome

Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank.

Authors: Sokolow R Bhattacharya A Kissas G et al.

Corporate Authors: Sokolow R Bhattacharya A Kissas G et al.

Source: Scientific reports [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39203. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Aorta, Thoracic*/physiopathology , Aorta, Thoracic*/diagnostic imaging , Models, Cardiovascular*, Humans ; Male ; Female ; Computer Simulation ; Middle Aged ; Biological Specimen Banks ; Aged ; Blood Pressure ; Hydrodynamics ; Hemodynamics ; Tomography, X-Ray Computed ; Aortic Aneurysm, Thoracic/physiopathology ; Hypertension/physiopathology