Výsledky vyhledávání - "Mitochondrial Membrane Transport Proteins"

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors.

Autoři: Albanese V Pedriali G Fabbri M a další

Zdroj: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2505907. Date of Electronic Publication: 2025 May 21.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Drug Design* , Mitochondrial Membrane Transport Proteins*/antagonists & inhibitors , Mitochondrial Membrane Transport Proteins*/metabolism , Spiro Compounds*/pharmacology , Spiro Compounds*/chemical synthesis , Spiro Compounds*/chemistry, Mitochondrial Permeability Transition Pore ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Animals ; Rats ; Myocytes, Cardiac/drug effects ; Models, Molecular

Dynamic Coupling between Tom22 Motions and Tom40 Pore Dynamics Modulates Ion Transport in the Mitochondrial TOM Complex.

Autoři: Acharya A Nussberger S Wang S a další

Zdroj: Journal of chemical information and modeling [J Chem Inf Model] 2025 Nov 24; Vol. 65 (22), pp. 12475-12488. Date of Electronic Publication: 2025 Oct 31.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Výrazy ze slovníku MeSH: Molecular Dynamics Simulation* , Mitochondrial Membrane Transport Proteins*/chemistry , Mitochondrial Membrane Transport Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/metabolism , Mitochondria*/metabolism, Mitochondrial Precursor Protein Import Complex Proteins ; Ion Transport ; Saccharomyces cerevisiae/metabolism ; Mitochondrial Membranes/metabolism

An orphan no more: SLC25A45 controls mitochondrial import of methylated amino acids.

Autoři: Sebo ZL Chandel NS

Zdroj: Molecular cell [Mol Cell] 2025 Nov 06; Vol. 85 (21), pp. 3893-3894.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mitochondria*/metabolism , Amino Acids*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Humans ; Methylation ; Carnitine/biosynthesis ; Carnitine/metabolism ; Biological Transport ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/genetics

SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis.

Autoři: Dias MM King MS Shokry E a další

Zdroj: Molecular cell [Mol Cell] 2025 Nov 06; Vol. 85 (21), pp. 4093-4104.e8. Date of Electronic Publication: 2025 Oct 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Výrazy ze slovníku MeSH: Carnitine*/biosynthesis , Mitochondria*/metabolism , Mitochondria*/genetics , Amino Acids*/metabolism , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Humans ; Lysine/metabolism ; Lysine/analogs & derivatives ; Methylation ; Arginine/metabolism ; Arginine/analogs & derivatives ; HEK293 Cells ; Proteolysis ; Animals

Dynamic TOM-TIM23 supercomplex directs mitochondrial protein translocation and sorting.

Autoři: Yang Y Wang S Wang G a další

Zdroj: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Nov; Vol. 32 (11), pp. 2231-2241. Date of Electronic Publication: 2025 Aug 28.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/chemistry , Mitochondria*/metabolism , Membrane Transport Proteins*/metabolism , Membrane Transport Proteins*/chemistry , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/chemistry, Mitochondrial Precursor Protein Import Complex Proteins ; Protein Transport ; Cryoelectron Microscopy ; Models, Molecular ; Hydrophobic and Hydrophilic Interactions

The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness.

Autoři: Zarges C Fieler H Rothemann RA a další

Zdroj: Redox biology [Redox Biol] 2025 Nov; Vol. 87, pp. 103884. Date of Electronic Publication: 2025 Oct 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Proteostasis* , Mitochondria*/metabolism , Mitochondria*/genetics , Disulfides*/metabolism , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Mitochondrial Proteins*/chemistry , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Mitochondrial Precursor Protein Import Complex Proteins ; Humans ; Protein Binding

Phloretin Suppresses the mPTP Abnormal Opening via the SHP-2/JAK2/BAX Axis to Ameliorate Nonalcoholic Steatohepatitis.

Autoři: Dong Y Wu X Li J a další

Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Oct 22; Vol. 73 (42), pp. 26700-26713. Date of Electronic Publication: 2025 Oct 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Non-alcoholic Fatty Liver Disease*/genetics , Non-alcoholic Fatty Liver Disease*/metabolism , Non-alcoholic Fatty Liver Disease*/drug therapy , Phloretin*/administration & dosage , Janus Kinase 2*/genetics , Janus Kinase 2*/metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/genetics , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Animals ; Mice ; Male ; Humans ; Mice, Inbred C57BL ; Mitochondrial Permeability Transition Pore/metabolism ; Mitochondria/metabolism ; Mitochondria/drug effects ; Mitochondria/genetics ; Signal Transduction/drug effects ; DNA, Mitochondrial/metabolism ; DNA, Mitochondrial/genetics

Structure and mechanism of the mitochondrial calcium transporter NCLX.

Autoři: Fan M Tsai CW Zhang J a další

Zdroj: Nature [Nature] 2025 Oct; Vol. 646 (8087), pp. 1272-1280. Date of Electronic Publication: 2025 Sep 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Výrazy ze slovníku MeSH: Sodium-Calcium Exchanger*/metabolism , Sodium-Calcium Exchanger*/chemistry , Mitochondrial Membrane Transport Proteins*/chemistry , Mitochondrial Membrane Transport Proteins*/metabolism, Animals ; Humans ; Calcium/metabolism ; Calcium Signaling ; Cryoelectron Microscopy ; Mitochondria/metabolism ; Mitochondria/chemistry ; Models, Molecular ; Protein Conformation ; Rats

Nynrin enhances cardiac function by inhibiting mitochondrial permeability transition pore opening upon myocardial ischemia/reperfusion injury.

Autoři: Wang Y Li Y Zhou Y a další

Zdroj: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2025 Dec; Vol. 209, pp. 93-103. Date of Electronic Publication: 2025 Oct 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mitochondrial Permeability Transition Pore*/metabolism , Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/physiopathology , Myocardial Reperfusion Injury*/pathology , Myocardial Reperfusion Injury*/genetics , Mitochondrial Membrane Transport Proteins*/metabolism, Animals ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Mice ; Peptidyl-Prolyl Isomerase F/metabolism ; Peptidyl-Prolyl Isomerase F/genetics ; Mice, Knockout ; Disease Models, Animal ; Male ; Cyclophilins/metabolism ; Mice, Inbred C57BL

Isosteviol attenuates myocardial ischemia-reperfusion damage by modulating Akt/GSK3β phosphorylation and mitochondrial permeability transition pore opening in female rats.

Autoři: Mestre Cordero VE Hermann R Fernández Pazos MLM a další

Zdroj: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Dec; Vol. 146, pp. 110059. Date of Electronic Publication: 2025 Aug 07.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Glycogen Synthase Kinase 3 beta*/metabolism , Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/drug therapy , Myocardial Reperfusion Injury*/prevention & control , Myocardial Reperfusion Injury*/pathology , Proto-Oncogene Proteins c-akt*/metabolism , Diterpenes, Kaurane*/pharmacology , Mitochondrial Membrane Transport Proteins*/metabolism , Cardiotonic Agents*/pharmacology, Animals ; Female ; Mitochondrial Permeability Transition Pore ; Rats, Wistar ; Phosphorylation/drug effects ; Rats ; Mitochondria, Heart/drug effects ; Mitochondria, Heart/metabolism ; Wortmannin ; Molecular Docking Simulation

MPTP mediated Ox-mtDNA release inducing macrophage pyroptosis and exacerbating MCD-induced MASH via promoting the ITPR3/Ca ²⁺ /NLRP3 pathway.

Autoři: Zhang Q Chen L Liu JY a další

Zdroj: Journal of translational medicine [J Transl Med] 2025 Nov 14; Vol. 23 (1), pp. 1289. Date of Electronic Publication: 2025 Nov 14.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: Pyroptosis*/drug effects , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Macrophages*/metabolism , Macrophages*/pathology , Inositol 1,4,5-Trisphosphate Receptors*/metabolism , DNA, Mitochondrial*/metabolism , Calcium*/metabolism , Signal Transduction* , Fatty Liver*/pathology , Fatty Liver*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism, Animals ; Mice, Inbred C57BL ; Humans ; Male ; Mitochondrial Permeability Transition Pore ; Choline ; Mice ; Oxidation-Reduction ; Methionine/deficiency

RAS-RH up-regulates the level of miR-126 and inhibits the opening of mPTP in a rat model of coronary microvascular disease.

Autoři: Jiang H Wang R Liu A a další

Zdroj: Microvascular research [Microvasc Res] 2025 Nov; Vol. 162, pp. 104856. Date of Electronic Publication: 2025 Aug 06.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0165035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9319 (Electronic) Linking ISSN: 00262862 NLM ISO Abbreviation: Microvasc Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: MicroRNAs*/metabolism , MicroRNAs*/genetics , Microcirculation*/drug effects , Microcirculation*/radiation effects , Endothelial Cells*/metabolism , Endothelial Cells*/ultrastructure , Endothelial Cells*/pathology , Endothelial Cells*/drug effects , Endothelial Cells*/radiation effects , Coronary Vessels*/metabolism , Coronary Vessels*/physiopathology , Coronary Vessels*/ultrastructure , Coronary Vessels*/pathology , Coronary Vessels*/radiation effects , Coronary Vessels*/drug effects , Coronary Circulation*/drug effects , Coronary Circulation*/radiation effects , Mitochondrial Membrane Transport Proteins*/metabolism , Microvessels*/metabolism , Microvessels*/physiopathology , Microvessels*/ultrastructure , Microvessels*/pathology , Mitochondria, Heart*/metabolism , Mitochondria, Heart*/ultrastructure , Mitochondria, Heart*/pathology , Mitochondria, Heart*/drug effects , Radiation Injuries, Experimental*/metabolism , Radiation Injuries, Experimental*/physiopathology , Radiation Injuries, Experimental*/pathology , Radiation Injuries, Experimental*/genetics , Radiation Injuries, Experimental*/prevention & control , ras Proteins*/metabolism, Animals ; Disease Models, Animal ; Male ; Mitochondrial Permeability Transition Pore ; Apoptosis ; Rats, Sprague-Dawley ; Up-Regulation ; Rats ; Cells, Cultured ; Signal Transduction

Tric proteins and TOM complex subunits are involved in the import of short DNA fragments into Arabidopsis mitochondria.

Autoři: T A T K D E V I T a další

Zdroj: Protoplasma [Protoplasma] 2025 Nov; Vol. 262 (6), pp. 1591-1603. Date of Electronic Publication: 2025 Jun 24.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Springer Country of Publication: Austria NLM ID: 9806853 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-6102 (Electronic) Linking ISSN: 0033183X NLM ISO Abbreviation: Protoplasma Subsets: MEDLINE

Výrazy ze slovníku MeSH: Arabidopsis*/metabolism , Arabidopsis*/genetics , Arabidopsis Proteins*/metabolism , Mitochondria*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism, Protein Subunits/metabolism ; Mitochondrial Precursor Protein Import Complex Proteins ; RNA, Transfer/metabolism

SIRT3 deficiency aggravates mitochondrial metabolic disorder and podocyte injury in DKD via MPC2 acetylation.

Autoři: Feng J Feng L Yan Y a další

Zdroj: Cellular signalling [Cell Signal] 2025 Nov; Vol. 135, pp. 112029. Date of Electronic Publication: 2025 Jul 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

Výrazy ze slovníku MeSH: Sirtuin 3*/deficiency , Sirtuin 3*/metabolism , Sirtuin 3*/genetics , Podocytes*/metabolism , Podocytes*/pathology , Mitochondria*/metabolism , Mitochondria*/pathology , Diabetic Nephropathies*/metabolism , Diabetic Nephropathies*/pathology , Mitochondrial Membrane Transport Proteins*/metabolism, Acetylation ; Animals ; Mice ; Apoptosis ; Humans ; Male ; Mice, Inbred C57BL ; Hyperglycemia ; Reactive Oxygen Species/metabolism

MPTP controls the release of mtDNA and induces endothelial cell PANoptosis in trichloroethylene-induced immune kidney injury.

Autoři: Xie H Zhao J Chen J a další

Zdroj: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 15; Vol. 1005, pp. 178118. Date of Electronic Publication: 2025 Sep 03.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Trichloroethylene*/toxicity , DNA, Mitochondrial*/metabolism , Mitochondrial Membrane Transport Proteins*/metabolism, Animals ; Humans ; Mice ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Male ; Tumor Necrosis Factor-alpha/blood ; Tumor Necrosis Factor-alpha/pharmacology ; Mitochondrial Permeability Transition Pore ; Reactive Oxygen Species/metabolism ; Interferon-gamma/blood ; Interferon-gamma/pharmacology ; Interferon Regulatory Factor-1/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mice, Inbred C57BL ; Kidney/drug effects ; Kidney/pathology ; Kidney/immunology ; Female ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism

Interaction of the mitochondrial calcium/proton exchanger TMBIM5 with MICU1.

Autoři: Zhang L Gottschalk B Dietsche F a další

Zdroj: Communications biology [Commun Biol] 2025 Sep 19; Vol. 8 (1), pp. 1348. Date of Electronic Publication: 2025 Sep 19.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics , Calcium-Binding Proteins*/metabolism , Calcium-Binding Proteins*/genetics , Mitochondria*/metabolism , Calcium*/metabolism , Cation Transport Proteins*/metabolism , Cation Transport Proteins*/genetics , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Calcium Channels*/metabolism , Calcium Channels*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Drosophila melanogaster*/metabolism , Drosophila melanogaster*/genetics, Animals ; Humans

Perturbing the mitochondrial pores using inhibitors of bax and bid along with cyclosporine-A could prevent cell death due to secondary injury after contusion spinal cord injury.

Autoři: Chandran P Chandramohan K Iyer K a další

Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Sep 08; Vol. 778, pp. 152373. Date of Electronic Publication: 2025 Jul 16.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Výrazy ze slovníku MeSH: Spinal Cord Injuries*/pathology , Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/drug therapy , Cyclosporine*/pharmacology , Cyclosporine*/administration & dosage , BH3 Interacting Domain Death Agonist Protein*/antagonists & inhibitors , BH3 Interacting Domain Death Agonist Protein*/metabolism , bcl-2-Associated X Protein*/antagonists & inhibitors , bcl-2-Associated X Protein*/metabolism , Mitochondrial Membrane Transport Proteins*/antagonists & inhibitors , Mitochondrial Membrane Transport Proteins*/metabolism, Animals ; Mitochondrial Permeability Transition Pore ; Apoptosis/drug effects ; Rats ; Rats, Sprague-Dawley ; Female

Deep phenotyping of patients with citrin deficiency in Singapore- single centre experience.

Autoři: Yeo M Goh JLK Koh AL a další

Zdroj: Molecular genetics and metabolism [Mol Genet Metab] 2025 Sep-Oct; Vol. 146 (1-2), pp. 109215. Date of Electronic Publication: 2025 Jul 29.

Způsob vydávání: Journal Article; Observational Study

Informace o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE

Výrazy ze slovníku MeSH: Citrullinemia*/genetics , Citrullinemia*/diagnosis , Citrullinemia*/pathology , Citrullinemia*/epidemiology , Mitochondrial Membrane Transport Proteins*/genetics , Mitochondrial Membrane Transport Proteins*/deficiency , Organic Anion Transporters*/deficiency , Organic Anion Transporters*/genetics, Humans ; Female ; Male ; Singapore/epidemiology ; Retrospective Studies ; Infant ; Phenotype ; Infant, Newborn ; Child, Preschool ; Neonatal Screening ; Child ; Mutation ; Adolescent ; Calcium-Binding Proteins

SCR Disease Name: Neonatal-onset citrullinemia type 2

TIMM8A-TIMM13 Complex Exerts Oncogenic Functions in Lung Cancer.

Autoři: Li S Shi K Wang Y a další

Zdroj: Oncology research [Oncol Res] 2025 Aug 28; Vol. 33 (9), pp. 2435-2449. Date of Electronic Publication: 2025 Aug 28 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Tech Science Press Country of Publication: United States NLM ID: 9208097 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-3906 (Electronic) Linking ISSN: 09650407 NLM ISO Abbreviation: Oncol Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Lung Neoplasms*/mortality , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics, Humans ; Cell Proliferation/genetics ; Cell Movement/genetics ; Mitochondrial Precursor Protein Import Complex Proteins ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Prognosis

The mammalian protein MTCH1 can function as an insertase.

Autoři: Dimogkioka AR Elias A Rapaport D

Zdroj: Journal of cell science [J Cell Sci] 2025 Aug 15; Vol. 138 (16). Date of Electronic Publication: 2025 Aug 15.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Mitochondrial Membrane Transport Proteins*/metabolism , Mitochondrial Membrane Transport Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics, Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Mitochondrial Membranes/metabolism ; Animals ; Mitochondria/metabolism ; Humans