Suchergebnisse - "Mitochondria/physiology"

A distribution-centered approach for analyzing human adipocyte size estimates and their association with obesity-related traits and mitochondrial function

Autoren: Julius Honecker Dominik Weidlich Simone Heisz et al.

Quelle: Int J Obes (Lond)
International Journal of Obesity

Schlagwörter: Adult, Male, 2. Zero hunger, 0301 basic medicine, 0303 health sciences, Article, Energy metabolism, Fat metabolism, Adipocytes/physiology [MeSH], Weights and Measures/instrumentation [MeSH], Female [MeSH], Weights and Measures/standards [MeSH], Adult [MeSH], Adipocytes/classification [MeSH], Humans [MeSH], Middle Aged [MeSH], Body Mass Index [MeSH], Male [MeSH], Obesity/physiopathology [MeSH], Adipose Tissue/metabolism [MeSH], Mitochondria/physiology [MeSH], Middle Aged, Weights and Measures, 16. Peace & justice, ddc, Body Mass Index, Mitochondria, 03 medical and health sciences, Adipose Tissue, Adipocytes, Humans, Female, Obesity

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.nature.com/articles/s41366-021-00883-6.pdf
https://pubmed.ncbi.nlm.nih.gov/34172828
https://www.ndm.ox.ac.uk/publications/1184660
https://pubmed.ncbi.nlm.nih.gov/34172828/
https://mediatum.ub.tum.de/node?id=1616100
https://www.bdi.ox.ac.uk/publications/1184660
https://europepmc.org/article/MED/34172828
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380540
https://repository.publisso.de/resource/frl:6443884
https://mediatum.ub.tum.de/1704449

Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program

Autoren: Nicolas Fasel O. A. Averina Vladimir P. Skulachev et al.

Quelle: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6491-6501
Proceedings of the National Academy of Sciences of the United States of America, 117(12):6491-6501

Schlagwörter: 0301 basic medicine, Aging, mitochondria, mild depolarization, antioxidant, aging, naked mole rat, Electron Transport, Mitochondrial Proteins, Mice, 03 medical and health sciences, Species Specificity, Chiroptera, Hexokinase, Animals, Membrane Potential, Mitochondrial, 0303 health sciences, Mole Rats, Adenosine Diphosphate/metabolism, Creatine/metabolism, Embryo, Mammalian, Glucose/metabolism, Hexokinase/metabolism, Mitochondria/metabolism, Mitochondria/physiology, Mitochondrial Membranes/enzymology, Mitochondrial Membranes/metabolism, Mitochondrial Membranes/physiology, Mitochondrial Proteins/metabolism, Organ Specificity, Reactive Oxygen Species/metabolism, Biological Sciences, Creatine, Mitochondria, 3. Good health, Adenosine Diphosphate, Glucose, 13. Climate action, Mitochondrial Membranes, Reactive Oxygen Species

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.pnas.org/content/pnas/117/12/6491.full.pdf
https://pubmed.ncbi.nlm.nih.gov/32152094
https://www.pnas.org/content/117/12/6491
https://europepmc.org/article/MED/32152094
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104298/
https://istina.msu.ru/publications/article/285317332/
https://serval.unil.ch/en/notice/serval:BIB_7F03D9804DEE
http://pubmed.ncbi.nlm.nih.gov/32152094/
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7F03D9804DEE2
https://serval.unil.ch/resource/serval:BIB_7F03D9804DEE.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_7F03D9804DEE
https://repository.publisso.de/resource/frl:6426945

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation.

Autoren: Smith, G.A. Lin, T.H. Sheehan, A.E. et al.

Schlagwörter: Animals, Axons/physiology, Axons/ultrastructure, Carrier Proteins/physiology, Drosophila, Drosophila Proteins/genetics, Drosophila Proteins/physiology, Female, Glutathione/metabolism, Membrane Proteins/genetics, Membrane Proteins/physiology, Mice, Inbred C57BL, Mitochondria/physiology, Neurons/metabolism, Oxidation-Reduction, Peroxidases/genetics, Peroxidases/physiology, Pregnancy, Primary Cell Culture, Thioredoxin Reductase 1/genetics, Thioredoxin Reductase 1/physiology, Gfzf, axons, glutathione, glutathione S-transferases, marf, mitochondria, mitofusin, neurons

Dateibeschreibung: application/pdf

Relation: Neuron; https://iris.unil.ch/handle/iris/51505; serval:BIB_1A35D62A2AC4; 000473726400007

Verfügbarkeit: https://iris.unil.ch/handle/iris/51505
https://doi.org/10.1016/j.neuron.2019.04.017

Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.

Autoren: Cebecauer, M. Guillaume, P. Hozák, P. et al.

Schlagwörter: Antioxidants/pharmacology, Apoptosis/drug effects, Apoptosis/immunology, Cells, Cultured, Clone Cells, Cyclosporine/pharmacology, Cytotoxicity, Immunologic/drug effects, Immunologic/immunology, Dimerization, Dose-Response Relationship, Immunologic, G0 Phase/drug effects, G0 Phase/immunology, Growth Inhibitors/physiology, H-2 Antigens/physiology, Kinetics, Membrane Potentials/physiology, Mitochondria/metabolism, Mitochondria/physiology, Necrosis, Oligopeptides/physiology, Reactive Oxygen Species/metabolism, Solubility, T-Lymphocytes, Cytotoxic/drug effects, Cytotoxic/immunology, Regulatory/drug effects, Regulatory/immunology

Dateibeschreibung: application/pdf

Relation: The Journal of Immunology; https://iris.unil.ch/handle/iris/223502; serval:BIB_69884E22BCE4; 000229298400036

Verfügbarkeit: https://iris.unil.ch/handle/iris/223502

A KRAB/KAP1-miRNA Cascade Regulates Erythropoiesis Through Stage-Specific Control of Mitophagy

Autoren: Barde, I. Rauwel, B. Marin-Florez, R.M. et al.

Schlagwörter: Anemia/genetics, Autophagy/genetics, Erythroblasts/metabolism, Erythroblasts/ultrastructure, Erythropoiesis/genetics, Membrane Proteins/metabolism, MicroRNAs/genetics, MicroRNAs/metabolism, Mitochondria/genetics, Mitochondria/physiology, Mitochondrial Proteins/metabolism, Nuclear Proteins/genetics, Nuclear Proteins/metabolism, Repressor Proteins/genetics, Repressor Proteins/metabolism, Transcription Factors/metabolism

Dateibeschreibung: application/pdf

Relation: Science; https://iris.unil.ch/handle/iris/43140; serval:BIB_46F2FB0DD990; 000317657500055

Verfügbarkeit: https://iris.unil.ch/handle/iris/43140
https://doi.org/10.1126/science.1232398

Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes

Autoren: Srinivas Gopala Patrick M. Vanderboom Katherine A. Klaus et al.

Quelle: The FASEB Journal. 33:4458-4472

Schlagwörter: Male, 0301 basic medicine, Dementia - etiology, Protein processing, Coumaric acids - pharmacology, Mice, Diabetes mellitus, Adenosine Triphosphate, Mitochondria - physiology, Insulin - therapeutic use, Homeostasis, Insulin, post-translational - drug effects, Phosphorylation, Monocarboxylic acid transporters - metabolism, Drug Implants, Dementia - metabolism, Dementia - prevention & control, 0303 health sciences, Brain - drug effects, experimental - metabolism, Monocarboxylic acid transporters - antagonists & inhibitors, Reactive oxygen species - metabolism, intranasal, Brain, Drug implants, Ketones, Insulin - pharmacology, Mitochondria, 3. Good health, Lactic acid - metabolism, Administration, Mitochondria - enzymology, experimental - drug therapy, Monocarboxylic Acid Transporters, Coumaric Acids, Nerve Tissue Proteins, Mitochondria - drug effects, Diabetes Mellitus, Experimental, 03 medical and health sciences, Energy metabolism - drug effects, inbred C57BL, Animals, experimental - psychology, Ketones - metabolism, Lactic Acid, Nerve tissue proteins - metabolism, Insulin - deficiency, Brain - metabolism, Administration, Intranasal, Insulin - administration & dosage, Mice, Inbred C57BL, Oxidative Stress, Oxidative stress, Adenosine triphosphate - biosynthesis, Dementia, Energy Metabolism

Zugangs-URL: https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.201802043R
https://pubmed.ncbi.nlm.nih.gov/30676773
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201802043R
https://europepmc.org/article/PMC/PMC6404590
https://www.fasebj.org/doi/10.1096/fj.201802043R
https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.201802043R
https://pubmed.ncbi.nlm.nih.gov/30676773/
https://mayoclinic.pure.elsevier.com/en/publications/insulin-deficiency-and-intranasal-insulin-alter-brain-mitochondri
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201802043R
https://doi.org/10.1096/fj.201802043R

HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway

Autoren: Fei Peng Wei Chang Qin Sun et al.

Quelle: Respiratory Research, Vol 21, Iss 1, Pp 1-12 (2020)

Schlagwörter: Sepsis, Endothelial injury, Pyroptosis, HGF, mTOR, Mitochondria physiology, Diseases of the respiratory system, RC705-779

Dateibeschreibung: electronic resource

Relation: http://link.springer.com/article/10.1186/s12931-020-01480-3; https://doaj.org/toc/1465-993X

Zugangs-URL: https://doaj.org/article/b687881532b544c2afac893b7102583c

Electrophysiological abnormalities in VLCAD deficient hiPSC-cardiomyocytes can be improved by lowering accumulation of fatty acid oxidation intermediates

Autoren: Knottnerus, Suzan J.G. Mengarelli, Isabella Wüst, Rob C.I. et al.

Weitere Verfasser: Knottnerus, Suzan J.G. Mengarelli, Isabella Wüst, Rob C.I. et al.

Schlagwörter: Acylcarnitines, Arrhythmias, hiPSC, VLCADD, Epoxy Compounds/pharmacology, Muscular Diseases/complications, Oxidation-Reduction, Acyl-CoA Dehydrogenase, Long-Chain/deficiency, Humans, Myocytes, Cardiac/drug effects, Congenital Bone Marrow Failure Syndromes/complications, Cardiac/etiology, Resveratrol/pharmacology, Mitochondrial Diseases/complications, Action Potentials, Lipid Metabolism, Inborn Errors/complications, Fatty Acids/chemistry, Cardiac Electrophysiology, Induced Pluripotent Stem Cells, Mitochondria/physiology, Catalysis, Molecular Biology, Spectroscopy, Computer Science Applications, Physical and Theoretical Chemistry, Organic Chemistry, Inorganic Chemistry

Dateibeschreibung: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/439713

Verfügbarkeit: https://dspace.library.uu.nl/handle/1874/439713

A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats

Autoren: Coudray, Charles Fouret, Gilles Lambert, Karen et al.

Weitere Verfasser: Coudray, Charles Fouret, Gilles Lambert, Karen et al.

Quelle: British Journal of Nutrition

Schlagwörter: Male, 0301 basic medicine, Lipids - analysis, IR insulin resistance, Ubiquinone, HFD high-fat diet, Weight Gain, MitoQ, Rats, Sprague-Dawley, Weight gain - drug effects, skeletal - chemistry, Mitochondria - physiology, high-fat, Phospholipids, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Metabolic Syndrome, 2. Zero hunger, 0303 health sciences, PC phosphatidylcholine, S20 - Physiologie de la nutrition humaine, Obesity - metabolism, Glucose intolerance - prevention & control, Fatty Acids, 000 - Autres thèmes, 1. No poverty, Liver - pathology, Organ Size, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Metabolic syndrome, Lipids, Mitochondria, 3. Good health, High-fat diet, Triglycerides - metabolism, Adipose Tissue, Liver, Muscle, Lipid metabolism - drug effects, Fatty acids - analysis, Ubiquinone - pharmacology, Metabolic syndrome - prevention & control, Mitochondria - drug effects, Diet, High-Fat, MitoQ mitochondrial-targeted lipophilic ubiquinone, SM sphingomyelin, 03 medical and health sciences, Phospholipids - analysis, Ubiquinone - analogs & derivatives, Glucose Intolerance, Animals, Obesity, Fatty acids, Muscle, Skeletal, Obesity - etiology, Triglycerides, skeletal - metabolism, Lipid Metabolism, Diet, Rats, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, skeletal - drug effects, DAG diacylglycerol, Organ size - drug effects, Sprague-Dawley, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, Adipose tissue - pathology

Dateibeschreibung: text; application/pdf

Zugangs-URL: https://hal.umontpellier.fr/hal-01804569/file/2016%20Coudray%20et%20al.%2C%20A%20mitochondrial%20targeted.pdf
https://pubmed.ncbi.nlm.nih.gov/26856891
https://pubmed.ncbi.nlm.nih.gov/26856891/
https://hal.umontpellier.fr/hal-01804569/document
https://www.ncbi.nlm.nih.gov/pubmed/26856891
https://hal.archives-ouvertes.fr/hal-01804569
https://agritrop.cirad.fr/580027/
https://europepmc.org/article/MED/26856891
http://agritrop.cirad.fr/580027/
http://agritrop.cirad.fr/580027/1/580027.pdf

Role of mitochondrial function in cell death and body metabolism

Autoren: Myung-Shik Lee College of Medicine Dept. of Life Science et al.

Weitere Verfasser: Myung-Shik Lee College of Medicine Dept. of Life Science et al.

Quelle: Frontiers in Bioscience. 21:1233-1244

Schlagwörter: 0301 basic medicine, Aging, Physiological, Longevity, Apoptosis, Longevity/physiology, Review, Mitochondrial/metabolism, Stress, Senescence, DNA, Mitochondrial, Mitokine, TNF-Related Apoptosis-Inducing Ligand, Necrosis, 03 medical and health sciences, Stress, Physiological, Cell Death/physiology, Autophagy, Animals, Humans, TNF-Related Apoptosis-Inducing Ligand/metabolism, Cell Death, Apoptosis/physiology, ROS, DNA, Mitochondria/physiology, Mitochondria, 3. Good health, 13. Climate action, Autophagy/physiology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/27100503
https://pubmed.ncbi.nlm.nih.gov/27100503/
https://www.bioscience.org/2016/v21/af/4453/list.htm

Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity

Autoren: Spanò V Montalbano A Carbone A et al.

Quelle: Spano, V, Motalbano, A, Carbone, A, Parrino, B, Diana, P, Cirrincione, G, Castagliuolo, I, Brun, P, Issinger, O-G, Tisi, S, Primac, I, Vedaldi, D, Salvador, A & Barraja, P 2014, ' Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotitc activity ', European Journal of Medicinal Chemistry, vol. 74, pp. 340-357 . https://doi.org/10.1016/j.ejmech.2013.10.014

Schlagwörter: 0301 basic medicine, Mitosis, Antiproliferative activity, Pyrroles -- chemistry, Cell Line, 03 medical and health sciences, Pyrrolo[3,4-h]quinazolines, Cell Death/drug effects, Cell Line, Tumor, Mitosis -- drug effects, Human Umbilical Vein Endothelial Cells, Mitochondria/physiology, Humans, Pyrroles, Cell Death -- drug effects, Pyrrolo[3, Pyrroles/chemistry, Tubulin polymerization, Vascular disrupting activity, 0303 health sciences, Tumor, 4-h]quinazolines, Cell Death, Mitochondria -- physiology, Antimitotic activity, Sciences bio-médicales et agricoles, Quinazolines/chemical synthesis, 6. Clean water, Mitochondria, 3. Good health, Lysosomes -- physiology, Quinazolines -- chemical synthesis -- chemistry -- pharmacology, Lysosomes/physiology, Quinazolines, Mitosis/drug effects, Lysosomes

Dateibeschreibung: 1 full-text file(s): application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/24486413
https://core.ac.uk/display/53509295
https://pure.unipa.it/it/publications/synthesis-of-a-new-class-of-pyrrolo34-hquinazolines-with-antimito-3
https://www.ncbi.nlm.nih.gov/pubmed/24486413
https://europepmc.org/article/MED/24486413
https://www.sciencedirect.com/science/article/pii/S0223523413006557
https://iris.unige.it/handle/11567/1024169
https://portal.findresearcher.sdu.dk/da/publications/b6ae4bf4-d9bc-43c9-ab15-2164ee4398c9
https://doi.org/10.1016/j.ejmech.2013.10.014
https://portal.findresearcher.sdu.dk/da/publications/b6ae4bf4-d9bc-43c9-ab15-2164ee4398c9
https://hdl.handle.net/11577/2857098

Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease

Autoren: Smith, Reuben L Soeters, Maarten R Wüst, Rob C I et al.

Quelle: Smith, R L, Soeters, M R, Wüst, R C I & Houtkooper, R H 2018, 'Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease', Endocrine Reviews, vol. 39, no. 4, pp. 489-517. https://doi.org/10.1210/er.2017-00211

Schlagwörter: Adaptation, Physiological/physiology, Animals, Energy Metabolism/physiology, Humans, Inflammation/metabolism, Metabolic Diseases/metabolism, Metabolic Networks and Pathways/physiology, Mitochondria/physiology, Neoplasms/metabolism, Signal Transduction/physiology

Relation: info:eu-repo/semantics/altIdentifier/pmid/29697773; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1871.1/1504ce9b-ccc3-488c-a275-e8e605c40327; info:eu-repo/semantics/altIdentifier/pissn/0163-769X; info:eu-repo/semantics/altIdentifier/eissn/1945-7189

Verfügbarkeit: https://research.vu.nl/en/publications/1504ce9b-ccc3-488c-a275-e8e605c40327
https://doi.org/10.1210/er.2017-00211
https://hdl.handle.net/1871.1/1504ce9b-ccc3-488c-a275-e8e605c40327
https://www.scopus.com/pages/publications/85054423381
https://www.scopus.com/inward/citedby.url?scp=85054423381&partnerID=8YFLogxK

Autophagy dysfunction and oxidative stress, two related mechanisms implicated in Retinitis Pigmentosa

Autoren: Moreno Sancho, María Luz. Mérida Donoso, Salvador. Bosch Morell, Francisco. et al.

Weitere Verfasser: Moreno Sancho, María Luz. Mérida Donoso, Salvador. Bosch Morell, Francisco. et al.

Schlagwörter: Retinitis pigmentosa - Treatment, Retina - Enfermedades - Tratamiento, Retina - Diseases - Treatment, Enfermedades genéticas - Tratamiento, Oxidative stress, Retinosis pigmentaria - Tratamiento, Mitocondrias - Fisiología, Mitochondria - Physiology, Estrés oxidativo, Genetic disorders - Treatment

Dateibeschreibung: application/pdf

Relation: Frontiers in Physiology, vol. 9 (julio 2018); Moreno, ML., Mérida, S., Bosch Morell, F., Miranda, M. and Villar, VM. (2018). Autophagy dysfunction and oxidative stress, two related mechanisms implicated in Retinitis Pigmentosa. Frontiers in Physiology, vol. 9 (july), art. 1008. DOI: https://doi.org/10.3389/fphys.2018.01008; http://hdl.handle.net/10637/10231; https://doi.org/10.3389/fphys.2018.01008

Verfügbarkeit: http://hdl.handle.net/10637/10231
https://doi.org/10.3389/fphys.2018.01008

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

Autoren: Manuel Reina Alejandro Martorell-Riera Juan Pablo Muñoz et al.

Weitere Verfasser: Manuel Reina Alejandro Martorell-Riera Juan Pablo Muñoz et al.

Quelle: Recercat. Dipósit de la Recerca de Catalunya
instname
Articles publicats en revistes (Biologia Cel·lular, Fisiologia i Immunologia)
Dipòsit Digital de la UB
Universidad de Barcelona
Embo Journal, vol. 33, no. 20, pp. 2388-2407

Schlagwörter: Dynamins, Male, 0301 basic medicine, Down-Regulation, Mitochondrial Dynamics, Mitocondris, Cell Line, GTP Phosphohydrolases, Mitochondrial Proteins, 03 medical and health sciences, Animals, Homeostasis, Humans, Cells, Cultured, Neurons, Cell Death, MEF2 Transcription Factors, Calcium/metabolism, Dynamins/genetics, Dynamins/metabolism, Gene Expression Regulation, MEF2 Transcription Factors/genetics, MEF2 Transcription Factors/metabolism, Membrane Proteins/genetics, Membrane Proteins/metabolism, Mitochondria/physiology, Mitochondrial Dynamics/physiology, Mitochondrial Proteins/genetics, Mitochondrial Proteins/metabolism, Models, Animal, Mutation, Neurons/physiology, Rats, Rats, Sprague-Dawley, bcl-2-Associated X Protein/genetics, bcl-2-Associated X Protein/metabolism, Malalties neurodegeneratives, Membrane Proteins, Neurodegenerative Diseases, 6. Clean water, Mitochondria, Calcium

Dateibeschreibung: application/pdf

Zugangs-URL: https://europepmc.org/articles/pmc4253527?pdf=render
https://pubmed.ncbi.nlm.nih.gov/25147362
http://hdl.handle.net/2445/127749
https://hdl.handle.net/2445/127749
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253527/figure/fig03/
https://zenodo.org/record/161776
http://diposit.ub.edu/dspace/bitstream/2445/127749/1/645393.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253527/
https://www.embopress.org/doi/full/10.15252/embj.201488327
https://emboj.embopress.org/content/33/20/2388
https://serval.unil.ch/notice/serval:BIB_833104A8E676
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_833104A8E6764
https://serval.unil.ch/resource/serval:BIB_833104A8E676.P001/REF.pdf

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption

Autoren: Joseph Washburn Moin A. Saleem Shawn Levy et al.

Weitere Verfasser: Joseph Washburn Moin A. Saleem Shawn Levy et al.

Quelle: J. Clin. Invest. 123, 5179-5189 (2013)
Journal of Clinical Investigation, vol 123, iss 12
Journal of Clinical Investigation

Schlagwörter: Exome/genetics, 0301 basic medicine, Biomedical and clinical sciences, Nephrotic Syndrome, Ubiquinone, DNA Mutational Analysis, Drug Resistance, Sequence Homology, Protein Kinases/physiology, Ubiquinone/analogs & derivatives, Protein Kinases/genetics, Ubiquinone/biosynthesis, Ubiquinone/antagonists & inhibitors, Medical and Health Sciences, Consanguinity, Adrenal Cortex Hormones, 2.1 Biological and endogenous factors, Drosophila Proteins, Exome, Adolescent, Amino Acid Sequence, Animals, Cells, Cultured, Child, Conserved Sequence, Disease Models, Animal, Fibroblasts, Gene Knockdown Techniques, Humans, Mitochondria, Molecular Sequence Data, Mutation, Podocytes, Protein Kinases, Rats, Sequence Alignment, Sequence Homology, Amino Acid, Young Adult, Zebrafish, Zebrafish Proteins, Aetiology, Fibroblasts/metabolism, 0303 health sciences, Cultured, Ubiquinone/therapeutic use, Biological Sciences, Nephrotic Syndrome/drug therapy, Amino Acid, Biological sciences, Nephrotic Syndrome/pathology, Podocytes/ultrastructure, Drosophila Proteins/genetics, Nephrotic Syndrome/genetics, Podocytes/metabolism, Cells, Immunology, Renal and urogenital, Adrenal Cortex Hormones/therapeutic use, Zebrafish Proteins/antagonists & inhibitors, Zebrafish/genetics, Drosophila Proteins/antagonists & inhibitors, 03 medical and health sciences, Clinical Research, Zebrafish Proteins/genetics, Complementary and Integrative Health, Genetics, Mitochondria/physiology, Biomedical and Clinical Sciences, Animal, Ubiquinone/metabolism, Health sciences, Adrenal Cortex Hormones/pharmacology, Protein Kinases/deficiency, Nephrotic Syndrome/metabolism, Disease Models, Zebrafish/embryology

Dateibeschreibung: application/pdf

Zugangs-URL: http://www.jci.org/articles/view/69000/files/pdf
https://pubmed.ncbi.nlm.nih.gov/24270420
https://europepmc.org/articles/PMC3859425
https://research-information.bris.ac.uk/en/publications/adck4-mutations-promote-steroid-resistant-nephrotic-syndrome-thro
https://snucm.elsevierpure.com/en/publications/adck4-mutations-promote-steroid-resistant-nephrotic-syndrome-thro
https://pubmed.ncbi.nlm.nih.gov/24270420/
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158497
https://doi.org/10.1172/JCI69000
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=28840
http://www.jci.org/articles/view/69000/pdf
https://hdl.handle.net/11577/3180009
https://doi.org/10.1172/JCI69000
https://escholarship.org/uc/item/3p0874pw

PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage

Autoren: Liliana Torosantucci Giuseppe Lamorte E. Cilia et al.

Weitere Verfasser: Liliana Torosantucci Giuseppe Lamorte E. Cilia et al.

Quelle: Cell Death & Differentiation. 20:920-930

Schlagwörter: 0301 basic medicine, Cell Survival, bcl-X Protein, Apoptosis, Biochemistry, biophysics & molecular biology [F05] [Life sciences], 03 medical and health sciences, Cell Line, Tumor, Autophagy, Mitochondria/physiology, Humans, Apoptosis Regulatory Proteins/physiology, Phosphorylation, Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant], Cell Survival/physiology, 0303 health sciences, Signal Transduction/physiology, Phosphorylation/physiology, Membrane Proteins/physiology, Membrane Proteins, Apoptosis/physiology, Mitochondria, HEK293 Cells, Protein Kinases/physiology, bcl-X Protein/metabolism, Beclin-1, Autophagy/physiology, Apoptosis Regulatory Proteins, Protein Kinases, Signal Transduction

Zugangs-URL: https://www.nature.com/articles/cdd201319.pdf
https://pubmed.ncbi.nlm.nih.gov/23519076
https://core.ac.uk/display/53801523
https://www.nature.com/articles/cdd201319.pdf
https://www.ncbi.nlm.nih.gov/pubmed/23519076
https://iris.unipv.it/handle/11571/1178000
https://www.nature.com/articles/cdd201319
http://orbilu.uni.lu/handle/10993/54786

Involvement of Oxidative Stress and Mitochondrial Apoptosis in the Pathogenesis of Pelvic Organ Prolapse

Autoren: Kyoung Hee Lee Sung Hyo Park Eun Jae Kim et al.

Weitere Verfasser: Kyoung Hee Lee Sung Hyo Park Eun Jae Kim et al.

Quelle: Journal of Urology. 189:588-594

Schlagwörter: apoptosis, Apoptosis, Middle Aged, pelvic organ prolapse, Pelvic Organ Prolapse, Apoptosis/physiology, Mitochondria/physiology, Mitochondria, Pelvic Organ Prolapse/etiology, Oxidative Stress, 03 medical and health sciences, 0302 clinical medicine, oxidative stress, Humans, Female, Prospective Studies

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/23260548
https://pubmed.ncbi.nlm.nih.gov/23260548/
https://www.auajournals.org/doi/10.1016/j.juro.2012.09.041
https://www.sciencedirect.com/science/article/pii/S0022534712048537
https://www.ncbi.nlm.nih.gov/pubmed/23260548
https://www.jurology.com/article/S0022-5347(12)04853-7/fulltext
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86278

On–off asymmetries in oxygen consumption kinetics of singleXenopus laevisskeletal muscle fibres suggest higher‐order control

Autoren: Harry B. Rossiter Rob C. I. Wüst Willem J. van der Laarse

Quelle: Wust, R C I, van der Laarse, W J & Rossiter, H B 2013, 'On-off asymmetries in oxygen consumption kinetics of single Xenopus laevis skeletal muscle fibres suggest higher-order control', Journal of Physiology-London, vol. 591, no. 3, pp. 731-744. https://doi.org/10.1113/jphysiol.2012.241992

Schlagwörter: 0301 basic medicine, 0303 health sciences, Muscle Fibers, Skeletal, In Vitro Techniques, Muscle Fibers, Oxygen Consumption/physiology, Mitochondria, Kinetics, Xenopus laevis, 03 medical and health sciences, Oxygen Consumption, Skeletal/physiology, Mitochondria/physiology, Animals, Female, Muscle Contraction/physiology, Muscle Contraction

Zugangs-URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577546
https://pubmed.ncbi.nlm.nih.gov/23165768
https://research.vumc.nl/en/publications/on-off-asymmetries-in-oxygen-consumption-kinetics-of-single-xenop
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577546/
https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/jphysiol.2012.241992
http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2012.241992/references
http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2012.241992/full
https://research.vu.nl/en/publications/on-off-asymmetries-in-oxygen-consumption-kinetics-of-single-xenop-2
https://research.vumc.nl/en/publications/a53243e9-88d2-4c9e-acfb-9f7a375d8909

The Graded Redefined Assessment of Strength Sensibility and Prehension: Reliability and Validity

Autoren: Armin Curt Dorcas E. Beaton Claudia Rudhe et al.

Weitere Verfasser: Armin Curt Dorcas E. Beaton Claudia Rudhe et al.

Quelle: Journal of Neurotrauma. 29:905-914

Schlagwörter: Male, Physical Therapy, Histones/metabolism, Lactic Acid/pharmacology, tetraplegia, Department of Physical Therapy, Disability Evaluation, 0302 clinical medicine, Musculoskeletal System, Physiotherapy, Fibroblasts/metabolism, Middle Aged, Biological Evolution, 3. Good health, 2728 Neurology (clinical), Thomas Jefferson University, RNA Interference, 10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center, Female, Caveolin 1/genetics, 0305 other medical science, Adult, impairment, Adolescent, Small Interfering/metabolism, Clinical Neurology, Down-Regulation, 610 Medicine & health, upper limb, Breast Neoplasms/genetics, Quadriplegia, Sensitivity and Specificity, Genomic Instability, Cell Line, Upper Extremity, outcome measures, Young Adult, 03 medical and health sciences, Reactive Oxygen Species/metabolism, Mitochondria/metabolism, Autophagy, Mitochondria/physiology, Humans, Spinal Cord Injuries, Aged, Nitric Oxide Synthase Type III/metabolism, Reproducibility of Results, Caveolin 1/metabolism, Coculture Techniques, Oxidative Stress, Cross-Sectional Studies, Kinesiotherapy, Breast Neoplasms/metabolism, Nitric Oxide/metabolism, RNA, DNA Damage

Dateibeschreibung: neu.2010.1504.pdf - application/pdf; application/pdf

Zugangs-URL: https://www.zora.uzh.ch/id/eprint/54781/1/neu.2010.1504.pdf
https://pubmed.ncbi.nlm.nih.gov/21568688
https://jdc.jefferson.edu/ptfp/11/
https://www.zora.uzh.ch/id/eprint/54781/1/neu.2010.1504.pdf
https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1011&context=ptfp
https://www.ncbi.nlm.nih.gov/pubmed/21568688
https://doi.org/10.5167/uzh-54781
https://online.liebertpub.com/doi/abs/10.1089/neu.2010.1504
https://www.zora.uzh.ch/id/eprint/54781/
https://doi.org/10.5167/uzh-54781

De la levure aux maladies neurodégénératives: Dix ans d’exploration des pathologies de la dynamique mitochondriale

Autoren: Lenaers, Guy Amati-Bonneau, Patrizia Delettre, Cécile et al.

Weitere Verfasser: Lenaers, Guy Amati-Bonneau, Patrizia Delettre, Cécile et al.

Quelle: médecine/sciences. 26:836-841

Schlagwörter: Optic Nerve Diseases/genetics, [SDV] Life Sciences [q-bio], 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Neurodegenerative Diseases/genetics/physiopathology, Axons/physiology, Humans, Mitochondria/physiology, Mitochondrial Diseases/genetics/physiopathology, Yeasts/physiology, GTP Phosphohydrolases/genetics, Oxidative Phosphorylation

Zugangs-URL: https://www.medecinesciences.org/articles/medsci/pdf/2010/09/medsci20102610p836.pdf