Suchergebnisse - "Metabolome"

Integrative multi-omics identifies coordinated alterations in the gut microbiome and in plasma and aqueous humor metabolomes in high myopic cataract.

Autoren: Gu X Ruan X Yang W et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 12; Vol. 15 (1), pp. 39636. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome* , Aqueous Humor*/metabolism , Cataract*/metabolism , Cataract*/microbiology , Cataract*/blood , Metabolome* , Myopia*/metabolism , Myopia*/microbiology , Myopia*/blood , Myopia*/complications, Humans ; Male ; Female ; Middle Aged ; Aged ; Metabolomics/methods ; RNA, Ribosomal, 16S/genetics ; Multiomics

Multi-omics analysis reveals important role for microbial-derived metabolites from Botryllus schlosseri in metal interactions.

Autoren: Guillén Matus DG Donaghy CM Vijayan N et al.

Quelle: MSystems [mSystems] 2025 Oct 22; Vol. 10 (10), pp. e0079325. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101680636 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5077 (Electronic) Linking ISSN: 23795077 NLM ISO Abbreviation: mSystems Subsets: MEDLINE

MeSH-Schlagworte: Urochordata*/microbiology , Urochordata*/metabolism , Microbiota* , Metals*/metabolism , Metabolome* , Bacteria*/metabolism , Bacteria*/classification, Animals ; Metabolomics/methods ; Multiomics

Comparative analysis of metabolome and transcriptomes to explore the inhibited influence of sonodynamic therapy combined with lonidamine on hepatocellular carcinoma.

Autoren: Tan H Tian H Chen Y et al.

Quelle: Drug delivery [Drug Deliv] 2025 Dec 31; Vol. 32 (1), pp. 2593600. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE

MeSH-Schlagworte: Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/therapy , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/therapy , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Liver Neoplasms*/genetics , Metabolome*/drug effects , Indazoles*/pharmacology , Indazoles*/administration & dosage , Transcriptome*/drug effects , Ultrasonic Therapy*/methods, Animals ; Humans ; Mice, Nude ; Mice ; Hep G2 Cells ; Xenograft Model Antitumor Assays ; Mice, Inbred BALB C ; Hematoporphyrins/administration & dosage ; Hematoporphyrins/pharmacology ; Hematoporphyrins/chemistry ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/administration & dosage ; Combined Modality Therapy ; Nanoparticles/chemistry ; Cell Line, Tumor ; Particle Size ; Male

Moderate increase in dietary fat induces alterations of microbiota and metabolome along the digestive tract prior to systemic metabolic changes: insights from a pig model.

Autoren: Ranson A Vazquez Gomez M Alili R et al.

Quelle: Gut microbes [Gut Microbes] 2025 Dec 31; Vol. 17 (1), pp. 2587964. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/drug effects , Metabolome* , Bacteria*/classification , Bacteria*/genetics , Bacteria*/metabolism , Bacteria*/isolation & purification , Dietary Fats*/metabolism , Dietary Fats*/administration & dosage , Gastrointestinal Tract*/microbiology , Gastrointestinal Tract*/metabolism, Animals ; Swine ; Male ; Female ; Intestine, Small/microbiology ; Intestine, Small/metabolism

Machine learning-enabled non-targeted metabolomics reveals nutritional and metabolic responses of Brachypodium distachyon to drought and elevated CO2.

Autoren: Chang HF Caso-McHugh T Des Marais DL

Quelle: Journal of experimental botany [J Exp Bot] 2025 Dec 04; Vol. 76 (22), pp. 7067-7085.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 9882906 Publication Model: Print Cited Medium: Internet ISSN: 1460-2431 (Electronic) Linking ISSN: 00220957 NLM ISO Abbreviation: J Exp Bot Subsets: MEDLINE

MeSH-Schlagworte: Brachypodium*/metabolism , Brachypodium*/physiology , Droughts* , Carbon Dioxide*/metabolism , Metabolomics*/methods , Machine Learning* , Metabolome*, Nitrogen/metabolism

Microbial and Metabolomic Variations Correlated With Gastric Cancer Subtypes and Prognosis.

Autoren: Yang Y Wen L Lin W et al.

Quelle: MicrobiologyOpen [Microbiologyopen] 2025 Dec; Vol. 14 (6), pp. e70139.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101588314 Publication Model: Print Cited Medium: Internet ISSN: 2045-8827 (Electronic) Linking ISSN: 20458827 NLM ISO Abbreviation: Microbiologyopen Subsets: MEDLINE

MeSH-Schlagworte: Stomach Neoplasms*/microbiology , Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/diagnosis , Stomach Neoplasms*/classification , Stomach Neoplasms*/mortality , Metabolome* , Microbiota* , Bacteria*/classification , Bacteria*/genetics , Bacteria*/isolation & purification, Humans ; Prognosis ; Male ; Female ; Middle Aged ; RNA, Ribosomal, 16S/genetics ; China ; Metabolomics ; Aged ; Sequence Analysis, DNA

Differential characteristics of meat flavor compounds, colonic microbiome and metabolome between Duroc × Landrace × Yorkshire pigs with high and low intramuscular fat of longissimus dorsi muscles.

Autoren: Wang D Ren Y Liao Y et al.

Quelle: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Dec; Vol. 221 (Pt 4), pp. 117579. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/physiology , Taste* , Metabolome* , Muscle, Skeletal*/metabolism , Pork Meat*/analysis , Adipose Tissue*/metabolism , Colon*/microbiology , Red Meat*/analysis, Animals ; Swine ; Volatile Organic Compounds/analysis

Molecular mechanism of anisaldehyde targeting the cell membrane of Ustilaginoidea virens based on integrated transcriptome and metabolome analyses.

Autoren: Hu X Ding Y Deng Y et al.

Quelle: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2025 Dec; Vol. 215, pp. 106656. Date of Electronic Publication: 2025 Aug 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE

MeSH-Schlagworte: Benzaldehydes*/pharmacology , Transcriptome*/drug effects , Metabolome*/drug effects , Cell Membrane*/drug effects , Cell Membrane*/metabolism , Hypocreales*/drug effects , Hypocreales*/metabolism , Hypocreales*/genetics , Hypocreales*/ultrastructure, Molecular Docking Simulation ; Fungal Proteins/metabolism ; Fungal Proteins/genetics ; Mycelium/drug effects ; Mycelium/ultrastructure

Analysis of the Metabolomic Profile in Serum of Mice Treated with RadioDefender, a Novel Radiation Medical Countermeasure.

Autoren: Carpenter AD Brink MW Li X et al.

Quelle: Radiation research [Radiat Res] 2025 Dec 01; Vol. 204 (6), pp. 581-594.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Radiation Research Society Country of Publication: United States NLM ID: 0401245 Publication Model: Print Cited Medium: Internet ISSN: 1938-5404 (Electronic) Linking ISSN: 00337587 NLM ISO Abbreviation: Radiat Res Subsets: MEDLINE

MeSH-Schlagworte: Amifostine*/pharmacology , Amifostine*/analogs & derivatives , Radiation-Protective Agents*/pharmacology , Metabolomics* , Metabolome*/drug effects , Metabolome*/radiation effects , Medical Countermeasures*, Animals ; Mice ; Male ; Acute Radiation Syndrome/blood ; Acute Radiation Syndrome/prevention & control ; Female ; Mercaptoethylamines

An integrated transcriptome, proteome and targeted metabolome analysis reveals genes and steroids related to gonadal development in Ruditapes philippinarum.

Autoren: Huang K Chen Y Gao Y et al.

Quelle: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101587. Date of Electronic Publication: 2025 Jul 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

MeSH-Schlagworte: Transcriptome* , Proteome*/metabolism , Proteome*/genetics , Bivalvia*/growth & development , Bivalvia*/genetics , Bivalvia*/metabolism , Metabolome* , Gonads*/growth & development , Gonads*/metabolism , Steroids*/metabolism, Animals ; Female ; Male ; Ovary/metabolism ; Ovary/growth & development ; Testis/metabolism ; Testis/growth & development ; Gene Expression Regulation, Developmental

Biochemistry and metabolomics revealed the regulation mechanism of osmolality in Sinonovacula constricta under salinity stress.

Autoren: Xia S Yu J Geng Y et al.

Quelle: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101578. Date of Electronic Publication: 2025 Jul 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

MeSH-Schlagworte: Metabolomics* , Salt Stress* , Bivalvia*/metabolism , Bivalvia*/physiology , Metabolome*, Animals ; Osmolar Concentration ; Hemolymph/metabolism ; Salinity ; Osmotic Pressure

Continental-scale metabolomic fingerprint and antialgal activity of coastal invasive plant Spartina alterniflora: regional heterogeneity and driving factors.

Autoren: Xu C Huang Y Ge Z et al.

Quelle: Environmental research [Environ Res] 2025 Dec 01; Vol. 286 (Pt 1), pp. 122741. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

MeSH-Schlagworte: Introduced Species* , Poaceae*/metabolism , Poaceae*/chemistry , Metabolome*, Metabolomics ; China ; Ecosystem

In Vivo/In vitro metabolic profiling and evaluation of key metabolites of QO-83, a novel KCNQ channel opener with antiepileptic potential.

Autoren: Yang L Zhang X Wang J et al.

Quelle: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 3), pp. 117381. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Anticonvulsants*/metabolism , Anticonvulsants*/pharmacology , Anticonvulsants*/pharmacokinetics , KCNQ Potassium Channels*/metabolism , KCNQ Potassium Channels*/agonists , Metabolome*/drug effects , Metabolome*/physiology, Animals ; Dogs ; Humans ; Rats ; Male ; Rats, Sprague-Dawley ; Microsomes, Liver/metabolism ; Microsomes, Liver/drug effects ; HEK293 Cells

Untargeted metabolomics reveals compositional alterations in the muscle tissue of hybrid crucian carp.

Autoren: Qin W He L Su J et al.

Quelle: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101620. Date of Electronic Publication: 2025 Aug 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

MeSH-Schlagworte: Carps*/metabolism , Carps*/genetics , Carps*/growth & development , Metabolomics*/methods , Muscles*/metabolism , Metabolome* , Hybridization, Genetic*, Animals

Associations between PM 2.5 components, temperature, and semen quality: Insights from seminal plasma metabolome.

Autoren: Tan JF Huang LL Lu ZH et al.

Quelle: Environmental research [Environ Res] 2025 Dec 01; Vol. 286 (Pt 3), pp. 122947. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

MeSH-Schlagworte: Semen* , Particulate Matter*/adverse effects , Particulate Matter*/analysis , Metabolome* , Semen Analysis* , Temperature* , Air Pollutants*/adverse effects , Air Pollutants*/analysis , Environmental Exposure*, Male ; Humans ; Adult ; China ; Prospective Studies ; Nitrates

Deciphering the microbiome-metabolome landscape of an inflammatory bowel disease inception cohort.

Autoren: Radhakrishnan ST Mullish BH Olbei ML et al.

Quelle: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2527863. Date of Electronic Publication: 2025 Jul 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome* , Metabolome* , Colitis, Ulcerative*/microbiology , Colitis, Ulcerative*/metabolism , Inflammatory Bowel Diseases*/microbiology , Inflammatory Bowel Diseases*/metabolism , Crohn Disease*/microbiology , Crohn Disease*/metabolism , Bacteria*/classification , Bacteria*/genetics , Bacteria*/isolation & purification , Bacteria*/metabolism, Humans ; Female ; Male ; Adult ; Feces/microbiology ; Middle Aged ; RNA, Ribosomal, 16S/genetics ; Cohort Studies ; Metabolomics ; Young Adult

Transcriptome and Metabolome Analysis Reveal the Reasons for the Formation of Tissue Specificity and Quality in the Underground Part of Saposhnikovia divaricata (Turcz.) Schischk.

Autoren: Chen Y Xu Z Sui J et al.

Quelle: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Dec; Vol. 39 (12), pp. e70240.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH-Schlagworte: Metabolome*/physiology , Metabolome*/genetics , Transcriptome*/genetics , Apiaceae*/chemistry , Apiaceae*/genetics , Apiaceae*/metabolism, Chromatography, High Pressure Liquid ; Plant Roots/chemistry ; Plant Roots/metabolism ; Plant Roots/genetics ; Xylem/chemistry ; Xylem/metabolism ; Metabolomics/methods ; Gene Expression Profiling ; Organ Specificity

Comparative biochemical, transcriptome and metabolome investigation on reproductive maturation of wild and captive female Monopterus albus.

Autoren: Yang H Xu Z Yuan Q et al.

Quelle: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Dec; Vol. 56, pp. 101567. Date of Electronic Publication: 2025 Jun 14.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

MeSH-Schlagworte: Metabolome* , Transcriptome* , Reproduction* , Ovary*/metabolism , Ovary*/growth & development , Smegmamorpha*/genetics , Smegmamorpha*/metabolism , Smegmamorpha*/physiology , Smegmamorpha*/growth & development, Animals ; Female ; Lipid Metabolism

Response of Rhinogobio ventralis skin to Ichthyophthirius multifiliis infection: pathological, transcriptomic and metabolomic analyses.

Autoren: Zhao Q Li S Wang S et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Dec; Vol. 167, pp. 110679. Date of Electronic Publication: 2025 Aug 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Fish Diseases*/immunology , Fish Diseases*/parasitology , Fish Diseases*/genetics , Hymenostomatida*/physiology , Ciliophora Infections*/veterinary , Ciliophora Infections*/immunology , Ciliophora Infections*/parasitology , Ciliophora Infections*/genetics , Transcriptome*/immunology , Skin*/pathology , Skin*/immunology , Skin*/metabolism , Skin*/parasitology , Metabolome*, Animals ; Gene Expression Profiling/veterinary ; Metabolomics

Microbiota and metabolite-based prediction tool for colonic polyposis with and without a known genetic driver.

Autoren: Katona BW Shukla A Hu W et al.

Quelle: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2474141. Date of Electronic Publication: 2025 Mar 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome* , Metabolome* , Colonic Polyps*/genetics , Colonic Polyps*/metabolism , Colonic Polyps*/microbiology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/microbiology, Humans ; RNA, Ribosomal, 16S/genetics ; Prospective Studies ; Male ; Female ; Adult ; Middle Aged ; Aged ; Feces/microbiology ; Intestinal Mucosa/microbiology