Suchergebnisse - "Messenger RNA"

LOCAS: multilabel mRNA localization with supervised contrastive learning Open Access.

Autoren: Abir, Abrar Rahman Tahmid, Md Toki Rahman, M Saifur

Quelle: Briefings in Bioinformatics. Jul2025, Vol. 26 Issue 4, p1-9. 9p.

Schlagwörter: MESSENGER RNA, DEEP learning, GENETIC regulation, NUCLEOTIDE sequence

mRNA folding algorithms for structure and codon optimization Open Access.

Autoren: Ward, Max Richardson, Mary Metkar, Mihir

Quelle: Briefings in Bioinformatics. Jul2025, Vol. 26 Issue 4, p1-16. 16p.

Schlagwörter: MESSENGER RNA, OPTIMIZATION algorithms, BIOINFORMATICS, VACCINE development, IMMUNE response, GENETIC code, RESEARCH methodology

Glutamine protects cow's ruminal epithelial cells from acid-induced injury in vitro.

Autoren: YUANXIAO LI YAN YU FEIYAN ZHAO et al.

Quelle: Czech Journal of Animal Science. 2024, Vol. 69 Issue 10, p410-418. 9p.

Schlagworte: Messenger RNA, Gene expression, Reverse transcriptase polymerase chain reaction, Cell junctions, Tight junctions, Occludins, Glutamine synthetase

Synthesis of mRNAs with a Varied Chemically Modified Poly(A) Tail and Study of Their Translation Efficiencies^†.

Autoren: Zhu, Xingyue Gao, Mingsong Huang, Chenyang et al.

Quelle: Chinese Journal of Chemistry. 12/15/2025, Vol. 43 Issue 24, p3589-3596. 8p.

Schlagwörter: *MESSENGER RNA, *RNA modification & restriction, *RNA-binding proteins, *GENETIC regulation, *RNA metabolism, *ADENOSINES, *PROTEIN synthesis

Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction.

Autoren: Tomczyk, Mateusz Kraszewska, Izabela Li, Gang et al.

Quelle: Circulation. 12/2/2025, Vol. 152 Issue 22, p1586-1589. 4p.

Schlagwörter: *MYOCARDIAL infarction, *MESSENGER RNA, *FIBROSIS, *CARDIAC output, *PROTEINS, *LIPOSOMES, *HEART failure, *CARDIOTONIC agents

Innovations in RNA therapeutics: a review of recent advances and emerging technologies.

Autoren: Dweh, Tuward J. Wulu, Glay Jr Eric Jallah, John Kessellie et al.

Quelle: Nucleosides, Nucleotides & Nucleic Acids. 2025, Vol. 44 Issue 12, p1034-1058. 25p.

Schlagwörter: *MESSENGER RNA, *RNA interference, *DRUG delivery systems, *ANTISENSE RNA, *INDIVIDUALIZED medicine, *CANCER treatment, *DRUG approval

Firma/Körperschaft: UNITED States. Food & Drug Administration

Delivery strategies of messenger RNA therapeutics for brain disorders.

Autoren: Youn, Kounghwa Oh, Sunmin Gil, Hyunchae et al.

Quelle: Bulletin of the Korean Chemical Society. Nov2025, p1. 19p. 5 Illustrations.

Schlagwörter: *BLOOD-brain barrier, *MESSENGER RNA, *LIPOSOMES, *EXOSOMES, *POLYMERIC drug delivery systems, *TRANSLATIONAL research, *BRAIN diseases

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation.

Autoren: Bird, Sophia Smith, Connor Habibi, Nahal et al.

Quelle: Advanced Functional Materials. Nov2025, p1. 11p. 6 Illustrations.

Schlagwörter: *MESSENGER RNA, *ULTRACENTRIFUGATION, *BIOCONJUGATES, *ALGORITHMS, *DISPERSION (Chemistry), *LIPOSOMES

A Comprehensive Lateral Flow Strip Assay for On‐Site mRNA Vaccine Quality Control in Decentralized Manufacturing.

Autoren: Luo, Dengwang Zhang, Ziwei Guo, Jing et al.

Quelle: Advanced Science. 11/20/2025, Vol. 12 Issue 43, p1-14. 14p.

Schlagwörter: *QUALITY control, *MESSENGER RNA, *MANUFACTURING industries, *IMMUNOASSAY, *REAL-time computing, *NANOPARTICLES

Structural Characterization of DDX23 5′ UTR Regulatory Elements and Their Targeting by LNA-Modified Antisense Oligonucleotides.

Autoren: Kamzeeva, Polina Shepelev, Nikita Zabbarova, Veronika et al.

Quelle: International Journal of Molecular Sciences. Nov2025, Vol. 26 Issue 22, p11047. 19p.

Schlagwörter: *MESSENGER RNA, *HAIRPIN (Genetics), *QUADRUPLEX nucleic acids, *GENETIC regulation, *ANTINEOPLASTIC agents, *GENES, *ANTISENSE RNA, *GENETIC translation

Autophagy regulates the maternal-to-zygotic transition through MAP1LC3B-mediated maternal mRNA decay.

Autoren: Liu, Doudou Guo, Shimeng Hu, Jing et al.

Quelle: Autophagy. Nov2025, p1-13. 13p. 6 Illustrations.

Schlagwörter: *AUTOPHAGY, *MESSENGER RNA, *REGULATION of growth, *RNA-binding proteins, *EMBRYOLOGY

The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation in Escherichia coli.

Autoren: Amarasinghe, Chathuddasie I. Mu-Hung Chang Männik, Jaana et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America. 11/11/2025, Vol. 122 Issue 45, p1-55. 66p.

Schlagwörter: *MESSENGER RNA, *RIBOSOMES, *CHROMOSOME segregation, *ESCHERICHIA coli, *FLUORESCENCE microscopy, *CELL division, *REACTION-diffusion equations

Sequence‐Specific Installation of Aryl Groups in RNA via DNA‐Catalyst Conjugates.

Autoren: Pratihar, Sumon Zhong, Wenrui Feng, Sheng et al.

Quelle: Angewandte Chemie International Edition. 11/10/2025, Vol. 64 Issue 46, p1-9. 9p.

Schlagwörter: *MESSENGER RNA, *ARYL group, *FLUORESCENT probes, *DEOXYRIBOZYMES, *ARYLATION, *PROTEIN synthesis, *RNA modification & restriction, *FUNCTIONAL groups

Deep generative models design mRNA sequences with enhanced translational capacity and stability.

Autoren: Zhang, He Liu, Hailong Xu, Yushan et al.

Quelle: Science. 11/6/2025, Vol. 390 Issue 6773, p1-14. 14p.

Schlagwörter: *MESSENGER RNA, *PROTEIN expression, *TRANSFORMER models, *PROBABILISTIC generative models, *CHEMICAL stability, *THERAPEUTICS

Harnessing Deaminated DNA to Modulate mRNA Translation for Controlled and Sequential Protein Expression.

Autoren: Choi, Jihun Jeong, Tae Ung Cabanting, Francis et al.

Quelle: Angewandte Chemie International Edition. Nov2025, p1. 9p. 6 Illustrations.

Schlagwörter: *MESSENGER RNA, *PROTEIN expression, *IMMUNOLOGICAL adjuvants, *RECOMBINANT DNA, *EXCISION repair, *IMMUNE response, *GENE expression

Productive mRNA chromatin escape is promoted by PRMT5 activity.

Autoren: DeAngelo, Joseph D. Maron, Maxim I. Roth, Jacob S. et al.

Quelle: Molecular Cell. Nov2025, Vol. 85 Issue 21, p4016-40403. 36388p.

Schlagwörter: *MESSENGER RNA, *RNA splicing, *CHROMATIN, *NUCLEOCYTOPLASMIC interactions, *GENE expression, *PROTEIN arginine methyltransferases, *METHYLTRANSFERASES, *TRANSCRIPTOMES

Enhanced mRNA Delivery in ARPE-19 Cells by RVG29-Modified Ready-to-Use LNP.

Autoren: Xiu, Yangyan Li, Yuhang Xiu, Yanghui

Quelle: Nano Life. Nov2025, p1. 10p.

Schlagwörter: *RETINAL diseases, *MESSENGER RNA, *OPHTHALMOLOGICAL therapeutics, *RHODOPSIN, *PEPTIDES, *LIPOSOMES, *NUCLEIC acids, *GENE delivery techniques

RNACOREX - RNA coregulatory network explorer and classifier.

Autoren: Oviedo-Madrid, Aitor González-Gomariz, José Armañanzas, Ruben

Quelle: PLoS Computational Biology. 11/3/2025, Vol. 21 Issue 10, p1-13. 13p.

Schlagwörter: *MICRORNA, *MESSENGER RNA, *CANCER genetics, *CLASSIFICATION, *DISEASE progression, *GENE regulatory networks, *RNA, *PYTHON programming language

Advances in mRNA‐Lipid Nanoparticle Engineering for Immune Cell Targeting and Immune Modulation.

Autoren: Kim, Cheesue Lee, Yeji Lee, Hyukjin et al.

Quelle: Small Methods. Nov2025, Vol. 9 Issue 11, p1-23. 23p.

Schlagwörter: *MESSENGER RNA, *IMMUNOTHERAPY, *LIPOSOMES, *IMMUNE response, *IMMUNOREGULATION, *TRANSLATIONAL research

The 3′ end of the tale—neglected isoforms in cancer.

Autoren: Dioken, Didem Naz Ozgul, Ibrahim Erson‐Bensan, Ayse Elif

Quelle: FEBS Letters. Nov2025, Vol. 599 Issue 21, p3029-3046. 18p.

Schlagwörter: *GENE expression, *MESSENGER RNA, *ALTERNATIVE RNA splicing, *TRANSCRIPTOMES, *RNA-binding proteins, *TUMORS, *NON-coding RNA