Výsledky vyhľadávania - "Messenger/metabolism"

Early total care and damage control orthopaedics result in partially contrasting patterns of microRNA expression at the fracture site and in the systemic circulation: an animal study

Autori: Rald V. M. Groven Ümit Mert Johannes Greven a ďalší

Zdroj: The Bone & Joint Journal. :193-203

Predmety: Fracture Healing, Fracture Healing/physiology, Multiple Trauma/genetics, Animal, Swine, Multiple Trauma, Messenger/metabolism, Liver/metabolism injuries, Real-Time Polymerase Chain Reaction, MicroRNAs, Disease Models, Animal, Fractures, Bone, Liver, Disease Models, MicroRNAs/metabolism, RNA, Animals, Female, RNA, Messenger, Bone, Fractures

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39889739

MCTS2 and distinct eIF2D roles in uORF-dependent translation regulation revealed by in vitro re-initiation assays

Autori: Romane Meurs Mara De Matos Adrian Bothe a ďalší

Zdroj: EMBO J
The EMBO journal, vol. 44, no. 3, pp. 854-876
The EMBO Journal, 44 (3)

Predmety: eIF2D, uORF, Re-Initiation, DENR-MCTS1, In Vitro Translation, Humans, HeLa Cells, Open Reading Frames, Protein Biosynthesis, Peptide Chain Initiation, Translational, Ribosomes/metabolism, Ribosomes/genetics, Gene Expression Regulation, Membrane Proteins/metabolism, Membrane Proteins/genetics, Neoplasm Proteins/metabolism, Neoplasm Proteins/genetics, Cell-Free System, RNA, Messenger/genetics, RNA, Messenger/metabolism, Oncogene Proteins, Eukaryotic Initiation Factor-2, Cell Cycle Proteins, Eukaryotic Initiation Factors, Article

Popis súboru: application/pdf; application/application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39748120
https://serval.unil.ch/notice/serval:BIB_49566FFF461F
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_49566FFF461F3
https://serval.unil.ch/resource/serval:BIB_49566FFF461F.P001/REF.pdf
http://hdl.handle.net/20.500.11850/714932

Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma

Autori: Galvan, Bartimée Ongena, Loïc Bruyr, Jonathan a ďalší

Zdroj: Nat Commun

Predmety: RNA, Messenger/genetics, Oncogene Proteins, Fusion, RNA, Messenger/metabolism, Biochimie, biophysique & biologie moléculaire, Article, Mice, Sarcoma, Ewing/metabolism, Cell Line, Tumor, Humans, Animals, RNA-Binding Protein EWS/metabolism, RNA, Messenger, RNA Stability/genetics, EWSR1 protein, human, Sarcoma, Ewing/genetics, Proto-Oncogene Protein c-fli-1, RNA-Binding Proteins, Sarcoma, Ewing/pathology, Bone Neoplasms/genetics, Oncogene Proteins, Fusion/metabolism, RNA-Binding Proteins/genetics, Life sciences, Gene Expression Regulation, Neoplastic, Proto-Oncogene Protein c-fli-1/genetics, Sciences du vivant, Oncogene Proteins, Fusion/genetics, Proto-Oncogene Protein c-fli-1/metabolism, RNA-Binding Protein EWS/genetics, RNA-Binding Protein EWS, RNA-Binding Proteins/metabolism, Bone Neoplasms/metabolism, FLI1 protein, human, Biochemistry, biophysics & molecular biology

Prístupová URL adresa: https://hdl.handle.net/2268/335247
https://doi.org/10.1038/s41467-025-61725-x

mRNA trafficking directs cell-size-scaling of mitochondria distribution and function

Autori: Joshua J. Bradbury Georgia E. Hulmes Ranjith Viswanathan a ďalší

Zdroj: Bradbury, J J, Hulmes, G E, Viswanathan, R, Costa, G, Lovegrove, H E & Herbert, S P 2025, 'mRNA trafficking directs cell-size-scaling of mitochondria distribution and function', Nature Communications, vol. 16, 7029. https://doi.org/10.1038/s41467-025-61940-6
Bradbury, J J, Hulmes, G E, Viswanathan, R, Costa, G, Lovegrove, H E & Herbert, S P 2025, 'mRNA trafficking directs cell-size-scaling of mitochondria distribution and function', Nature Communications, vol. 16, no. 1, pp. 7029. https://doi.org/10.1038/s41467-025-61940-6
Bradbury, J J, Hulmes, G E, Viswanathan, R, Costa, G, Lovegrove, H E & Herbert, S P 2025 ' mRNA trafficking directs cell-size-scaling of mitochondria distribution and function ' . https://doi.org/10.1101/2025.05.05.652164

Predmety: Saccharomyces cerevisiae/metabolism, 3' Untranslated Regions/genetics, Mitochondria/metabolism, RNA, Messenger/metabolism, RNA, Humans, Messenger/metabolism, Saccharomyces cerevisiae Proteins/metabolism, RNA Transport, Cell Size

Popis súboru: application/pdf

Prístupová URL adresa: https://research.manchester.ac.uk/en/publications/107b9a02-9026-4c47-9b23-73974ef8d0df
https://doi.org/10.1038/s41467-025-61940-6
https://pure.qub.ac.uk/en/publications/72058e32-f644-46f0-b607-3cb7c53e0805
https://research.manchester.ac.uk/en/publications/31374a9c-34df-4320-9446-452aa6eb2767
http://biorxiv.org/lookup/doi/10.1101/2025.05.05.652164
https://doi.org/10.1101/2025.05.05.652164

Phosphate deficiency alters transcript isoforms via alternative transcription start sites

Autori: Rodrigo S. Reis Joaquín Clúa Aime Jaskolowski a ďalší

Zdroj: The Plant journal, vol. 120, no. 1, pp. 218-233
S Reis, Rodrigo; Clúa, Joaquín; Jaskolowski, Aime; Deforges, Jules; Jacques-Vuarambon, Dominique; Guex, Nicolas; Poirier, Yves (2024). Phosphate deficiency alters transcript isoforms via alternative transcription start sites. The Plant Journal, 120(1), pp. 218-233. Blackwell Science 10.1111/tpj.16982 <http://dx.doi.org/10.1111/tpj.16982>

Predmety: 2. Zero hunger, Gene Expression Regulation, Plant, Arabidopsis Proteins, Arabidopsis, 570 Life sciences, biology, Arabidopsis/genetics, Arabidopsis/metabolism, Transcription Initiation Site, Phosphates/deficiency, Phosphates/metabolism, 5' Untranslated Regions/genetics, RNA, Messenger/genetics, RNA, Messenger/metabolism, Arabidopsis Proteins/genetics, Arabidopsis Proteins/metabolism, ECT4, noncoding RNA, phosphate deficiency, transcription start sites, upstream open reading frame, RNA, Messenger, 580 Plants (Botany), 5' Untranslated Regions, Phosphates

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39164918
https://serval.unil.ch/notice/serval:BIB_DFA16258AAE3
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DFA16258AAE33
https://serval.unil.ch/resource/serval:BIB_DFA16258AAE3.P001/REF.pdf
https://boris.unibe.ch/199898/

Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells

Autori: Hooman Bagheri Hana Friedman Amanda Hadwen a ďalší

Zdroj: Glia

Predmety: myelin sheath thickness and length, Male, hypomyelination, Neuroglia/metabolism, Mbp transcription, microglia, Messenger/metabolism, Mice, Transgenic, Inbred C57BL, Transgenic, Mice, astrocyte, Animals, RNA, Messenger, Myelin Sheath, Myelin Sheath/metabolism, Myelin Basic Protein/metabolism, Myelin Basic Protein, myelin basic protein, Mice, Inbred C57BL, hypermyelination, myelin elaboration and plasticity, oligodendrocyte and oligodendrocyte progenitor cell, RNA, Astrocyte, Neuroglia, Research Article

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39023138
https://discovery-pp.ucl.ac.uk/id/eprint/10195293/

Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment

Autori: Cosima Rhein Isabella Apelt Franziska Werner a ďalší

Zdroj: J Neural Transm (Vienna)

Predmety: Male, Adult, Therapy outcome, Female [MeSH], Stress Disorders, Post-Traumatic/genetics [MeSH], Stress Disorders, Post-Traumatic/metabolism [MeSH], Adult [MeSH], Interleukin 6, Posttraumatic stress disorder, Humans [MeSH], Prospective Studies [MeSH], Psychotherapy, Middle Aged [MeSH], Stress Disorders, Post-Traumatic/drug therapy [MeSH], Anti-inflammatory drugs, Anti-Inflammatory Agents/pharmacology [MeSH], Male [MeSH], Psychiatry and Preclinical Psychiatric Studies - Original Article, Anti-Inflammatory Agents/administration, Interleukin-6/genetics [MeSH], Depression/drug therapy [MeSH], RNA, Messenger/metabolism [MeSH], Interleukin-6, Depression, Anti-Inflammatory Agents, Middle Aged, Stress Disorders, Post-Traumatic, 03 medical and health sciences, 0302 clinical medicine, Humans, Female, RNA, Messenger, Prospective Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38613673
https://repository.publisso.de/resource/frl:6523051

Effects of age and diet consistency on the expression of myosin heavy‐chain isoforms on jaw‐closing and jaw‐opening muscles in a rat model

Autori: Schaub, Leandra Lagou, Aikaterini Djeraba Ait-Lounis, Aouatef a ďalší

Zdroj: Schaub, Leandra; Lagou, Aikaterini; Ait-Lounis, Aouatef; Kiliaridis, Stavros; Antonarakis, Gregory S (2024). Effects of age and diet consistency on the expression of myosin heavy-chain isoforms on jaw-closing and jaw-opening muscles in a rat model. Journal of oral rehabilitation, 51(6), pp. 1016-1024. Wiley 10.1111/joor.13676 <http://dx.doi.org/10.1111/joor.13676>

Predmety: Male, Aging, Soft diet, Aging / physiology, 617.6, RNA, Messenger / metabolism, 610 Medicine & health, Masticatory Muscles / physiology, Real-Time Polymerase Chain Reaction, Jaw muscles, Animals, Protein Isoforms, Aging / metabolism, RNA, Messenger, Rats, Wistar, Masseter Muscle / physiology, 2. Zero hunger, Myosin Heavy Chains, Masseter Muscle / metabolism, Myosin Heavy Chains / metabolism, Masseter Muscle, Messenger RNA, Masticatory Muscles / metabolism, Protein Isoforms / metabolism, Age Factors, Rats, Diet, 3. Good health, Myosin heavy chains, Masticatory Muscles

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38475932
https://boris.unibe.ch/194215/

Systematic and quantitative analysis of stop codon readthrough in Rett syndrome nonsense mutations

Autori: Dennis Lebeda Adrian Fierenz Lina Werfel a ďalší

Prispievatelia: Dennis Lebeda Adrian Fierenz Lina Werfel a ďalší

Zdroj: J Mol Med (Berl)

Predmety: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, HEK293 Cells, Codon, Nonsense, Methyl-CpG-Binding Protein 2, Protein Biosynthesis, Rett Syndrome, Codon, Terminator, Humans, Original Article, RNA, Messenger, Methyl-CpG-Binding Protein 2/genetics [MeSH], Rare disease, Humans [MeSH], Aminoglycoside, RNA, Messenger/genetics [MeSH], Codon, Nonsense [MeSH], Protein Biosynthesis [MeSH], Translational readthrough, Rett Syndrome/metabolism [MeSH], Rett Syndrome/genetics [MeSH], Personalized medicine, Methyl-CpG-Binding Protein 2/metabolism [MeSH], HEK293 Cells [MeSH], Codon, Terminator [MeSH], Rett syndrome, RNA, Messenger/metabolism [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38430393
https://pub.uni-bielefeld.de/record/2987678
https://doi.org/10.1007/s00109-024-02436-6
https://resolver.sub.uni-goettingen.de/purl?gro-2/142422
https://sfb1002.med.uni-goettingen.de/production/literature/publications/512
https://repository.publisso.de/resource/frl:6521575

Initial characterization of a transgenic mouse with overexpression of the human D1-dopamine receptor in the heart

Autori: Rayo Abella, Lina Maria Jacob, Hannes Hesse, Christin a ďalší

Zdroj: Naunyn Schmiedebergs Arch Pharmacol

Predmety: Male, 0301 basic medicine, ddc:610, 0303 health sciences, Mice, Inbred C57BL [MeSH], Dopamine/pharmacology [MeSH], RNA, Messenger/genetics [MeSH], Heart/drug effects [MeSH], Heart Atria/drug effects [MeSH], Human D, Mice, Transgenic [MeSH], Dopamine/metabolism [MeSH], Male [MeSH], 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology [MeSH], Heart Rate/drug effects [MeSH], Myocytes, Cardiac/metabolism [MeSH], Myocytes, Cardiac/drug effects [MeSH], Receptors, Dopamine D1/genetics [MeSH], Force of contraction, Receptors, Dopamine D1/metabolism [MeSH], RNA, Messenger/metabolism [MeSH], Myocardium/metabolism [MeSH], Dopamine Agonists/pharmacology [MeSH], Humans [MeSH], Animals [MeSH], Transgenic mouse heart, Mice [MeSH], Myocardial Contraction/drug effects [MeSH], Heart/physiology [MeSH], Research, Heart Atria/metabolism [MeSH], Dopamine, Myocardium, Receptors, Dopamine D1, Heart, Mice, Transgenic, Myocardial Contraction, Mice, Inbred C57BL, Mice, 03 medical and health sciences, Heart Rate, Dopamine Agonists, Animals, Humans, Myocytes, Cardiac, 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, Heart Atria, RNA, Messenger

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38177456
https://repository.publisso.de/resource/frl:6522921

N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease

Autori: Marko Jörg Johanna E. Plehn Marco Kristen a ďalší

Prispievatelia: Marko Jörg Johanna E. Plehn Marco Kristen a ďalší

Zdroj: Mol Psychiatry

Predmety: Male, Aged, 80 and over, 540 Chemistry and allied sciences, Adenosine, Electron Transport Complex I, Amyloid beta-Peptides, 610 Medizin, Methyltransferases, Methylation, Article, Mitochondria, Mitochondrial Proteins, Alzheimer Disease, 540 Chemie, 610 Medical sciences, Humans, Aged, 80 and over [MeSH], Aged [MeSH], Adenosine/metabolism [MeSH], 38/90, 692/699/476, 96/109, Electron Transport Complex I/genetics [MeSH], Male [MeSH], Mitochondrial Proteins/genetics [MeSH], 82/58, Alzheimer Disease/metabolism [MeSH], RNA, Messenger/metabolism [MeSH], 13/89, Female [MeSH], Mitochondrial Proteins/metabolism [MeSH], 82/80, Methylation [MeSH], Mitochondria/metabolism [MeSH], Amyloid beta-Peptides/metabolism [MeSH], Humans [MeSH], Electron Transport Complex I/metabolism [MeSH], 631/45, 38/71, Methyltransferases/genetics [MeSH], Alzheimer Disease/genetics [MeSH], Methyltransferases/metabolism [MeSH], article, Female, RNA, Messenger, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38287100
https://repository.publisso.de/resource/frl:6504569

Not4-dependent targeting of MMF1 mRNA to mitochondria limits its expression via ribosome pausing, Egd1 ubiquitination, Caf130, no-go-decay and autophagy

Autori: Chen, Siyu Allen, George Edward Panasenko, Olesya a ďalší

Zdroj: Nucleic Acids Res

Predmety: Autophagy / genetics, Saccharomyces cerevisiae Proteins, RNA, Messenger / metabolism, Ribosomes / metabolism, Saccharomyces cerevisiae, Ribosomes / genetics, Mitochondrial Proteins, Saccharomyces cerevisiae Proteins / genetics, Autophagy, Saccharomyces cerevisiae / metabolism, RNA, Messenger, Mitochondrial Proteins / genetics, Molecular Biology, Saccharomyces cerevisiae Proteins / metabolism, Membrane Proteins / genetics, RNA, Messenger / genetics, Mitochondria / metabolism, Ubiquitination, Membrane Proteins, Mitochondria, Mitochondria / genetics, Mitochondrial Proteins / metabolism, Saccharomyces cerevisiae / genetics, Ribosomes

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37094076
https://archive-ouverte.unige.ch/unige:172792
https://doi.org/10.1093/nar/gkad299

Revealing determinants of translation efficiency via whole-gene codon randomization and machine learning

Autori: Nieuwkoop, Thijs Terlouw, Barbara R. Stevens, Katherine G. a ďalší

Prispievatelia: Nieuwkoop, Thijs Terlouw, Barbara R. Stevens, Katherine G. a ďalší

Zdroj: Nucleic Acids Res

Predmety: 0301 basic medicine, RNA, Messenger/metabolism, Messenger/metabolism, 3. Good health, Machine Learning, Escherichia coli/genetics, Random Allocation, 03 medical and health sciences, Protein Biosynthesis, Escherichia coli, Life Science, Codon/genetics, RNA, RNA, Messenger, Codon, Molecular Biology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36718935
https://research-portal.uu.nl/en/publications/478f8c01-2940-4e09-8b2a-662f9b3fa490
https://doi.org/10.1093/nar/gkad035
https://research.wur.nl/en/publications/revealing-determinants-of-translation-efficiency-via-whole-gene-c
https://doi.org/10.1093/nar/gkad035
https://dspace.library.uu.nl/handle/1874/434735

Retinol-binding protein type 1 expression predicts poor prognosis in head and neck squamous cell carcinoma

Autori: Fu, Ling-ling Yan, Ming Yu, Xin a ďalší

Zdroj: BMC Cancer
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)

Predmety: Male, RBP1, Squamous Cell Carcinoma of Head and Neck, Research, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Head and neck squamous cell carcinoma, Retinol-Binding Proteins, Cellular, Prognosis biomarker, DNA Methylation, Middle Aged, Prognosis, Gene Expression Regulation, Neoplastic, Nomograms, Gene Expression Regulation, Neoplastic [MeSH], Aged [MeSH], Squamous Cell Carcinoma of Head and Neck/pathology [MeSH], Retinol-Binding Proteins, Cellular [MeSH], Head and Neck Neoplasms/genetics [MeSH], RNA, Messenger/genetics [MeSH], Male [MeSH], Squamous Cell Carcinoma of Head and Neck/mortality [MeSH], Retinol-Binding Proteins, Plasma/genetics [MeSH], RNA, Messenger/metabolism [MeSH], Female [MeSH], Squamous Cell Carcinoma of Head and Neck/metabolism [MeSH], Bioinformatic analysis, Humans [MeSH], Head and Neck Neoplasms/metabolism [MeSH], Retinol-Binding Proteins, Plasma/metabolism [MeSH], Middle Aged [MeSH], Head and Neck Neoplasms/mortality [MeSH], Squamous Cell Carcinoma of Head and Neck/genetics [MeSH], Nomograms [MeSH], Biomarkers, Tumor/metabolism [MeSH], DNA Methylation [MeSH], Biomarkers, Tumor/genetics [MeSH], Prognosis [MeSH], Head and Neck Neoplasms/pathology [MeSH], Head and Neck Neoplasms, Biomarkers, Tumor, Humans, Female, RNA, Messenger, Retinol-Binding Proteins, Plasma, RC254-282, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39407127
https://doaj.org/article/31bfdde01fcb44feb8485bed198b315c
https://repository.publisso.de/resource/frl:6512630

The scaffolding protein AKAP12 regulates mRNA localization and translation

Autori: Madeleine R. Smith Parisa Naeli Seyed M. Jafarnejad a ďalší

Zdroj: Proc Natl Acad Sci U S A
Smith, M R, Naeli, P, Jafarnejad, S M & Costa, G 2024, 'The scaffolding protein AKAP12 regulates mRNA localization and translation', Proceedings of the National Academy of Sciences, vol. 121, no. 18, e2320609121. https://doi.org/10.1073/pnas.2320609121

Predmety: 0301 basic medicine, Cell Membrane - metabolism, Cell Cycle Proteins - metabolism - genetics, RNA, Messenger - metabolism - genetics, mRNA, translation, A Kinase Anchor Proteins, Cell Cycle Proteins, Endothelial Cells - metabolism, A Kinase Anchor Proteins - metabolism - genetics, localization, Messenger - metabolism - genetics, angiogenesis, Mice, 03 medical and health sciences, Cell Movement, endothelial, Humans, Animals, RNA, Messenger, Pseudopodia, Pseudopodia - metabolism - genetics, 0303 health sciences, Cell Membrane, Endothelial Cells, Biological Sciences, Protein Biosynthesis, RNA

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38652739
https://pure.qub.ac.uk/en/publications/0f4e09b1-b560-41e1-9142-88b7fa578d37

Targeting TGF beta receptor 1 in head and neck squamous cell carcinoma

Autori: Jank, Bernhard J Schnoell, Julia Kladnik, Katharina a ďalší

Zdroj: Oral Diseases. 30:1114-1127

Predmety: Male, Radiation-Sensitizing Agents, Receptor, Transforming Growth Factor-beta Type I, Antineoplastic Agents, Radiation-Sensitizing Agents Therapeutic Use, Receptor, Transforming Growth Factor-beta Type I Antagonists & Inhibitors, Cancer-Associated Fibroblasts, Cell Line, Tumor, Tumor Microenvironment, Receptor, Transforming Growth Factor-beta Type I Metabolism, Humans, RNA, Messenger, RNA, Messenger Metabolism, Cancer-Associated Fibroblasts Metabolism, Antineoplastic Agents Therapeutic Use, Aged, Head and Neck Neoplasms Genetics, Aniline Compounds, Head and Neck Neoplasms Metabolism, Squamous Cell Carcinoma of Head and Neck, Middle Aged, Triazoles, Antineoplastic Agents Pharmacology, Radiation-Sensitizing Agents Pharmacology, Cancer-Associated Fibroblasts Drug Effects, Squamous Cell Carcinoma of Head and Neck Metabolism, Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck Pathology, Female, Squamous Cell Carcinoma of Head and Neck Genetics

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37154295
https://phaidra.vetmeduni.ac.at/o:4246
https://doi.org/10.1111/odi.14594

Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma

Autori: Itakura, Koji Fujino, Naoya Kamide, Yosuke a ďalší

Zdroj: Allergology International, Vol 71, Iss 3, Pp 383-394 (2022)
Itakura, K, Fujino, N, Kamide, Y, Saito, I, Yamada, M, Okutomo, K, Tsukita, Y, Saito, T, Ichikawa, T, Numakura, T, Kyogoku, Y, Aizawa, H, Ono, Y, Matsumoto, S, Hussell, T, Taniguchi, M, Ichinose, M & Sugiura, H 2022, 'Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma', Allergology international : official journal of the Japanese Society of Allergology, vol. 71, no. 3, pp. 383-394. https://doi.org/10.1016/j.alit.2022.02.010

Predmety: Axl receptor tyrosine kinase, 0301 basic medicine, RNA, Messenger/metabolism, Messenger/metabolism, Small Interfering, Mice, 03 medical and health sciences, Proto-Oncogene Proteins, Granulocyte-Macrophage Colony-Stimulating Factor/genetics, Animals, Humans, RNA, Messenger, RNA, Small Interfering, Granulocyte-macrophage colony-stimulating factor, Inflammation, Asthma/drug therapy, Eosinophils/metabolism, Receptor Protein-Tyrosine Kinases/genetics, Inflammation/metabolism, Granulocyte-Macrophage Colony-Stimulating Factor, Receptor Protein-Tyrosine Kinases, RC581-607, Eosinophilic inflammation, Axl Receptor Tyrosine Kinase, Asthma, Eosinophils, Proto-Oncogene Proteins/genetics, Airway, RNA, Immunologic diseases. Allergy

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35459569
https://doaj.org/article/940d6e3cedc14ea78ab7602d71eff235

Ceruloplasmin‐deficient mice show changes inPTMprofiles of proteins involved in messengerRNAprocessing and neuronal projections and synaptic processes

Autori: Birgitte Villadsen Camilla Thygesen Manuela Grebing a ďalší

Zdroj: Journal of Neurochemistry. 165:76-94

Predmety: Proteomics, 0301 basic medicine, RNA Processing, Proteome, Iron, Proteome/metabolism, Ceruloplasmin/genetics, Post-Transcriptional, Messenger/metabolism, Mice, 03 medical and health sciences, post-translational modifications, Humans, Animals, neurodegenerative diseases, RNA, Messenger, Neurodegenerative Diseases/metabolism, RNA Processing, Post-Transcriptional, Protein Processing, mass spectrometry, 0303 health sciences, Post-Translational, Ceruloplasmin, Neurodegenerative Diseases, Iron Metabolism Disorders, 3. Good health, RNA, mRNA processing, synaptic processes, Iron/metabolism, Protein Processing, Post-Translational

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36583241
https://portal.findresearcher.sdu.dk/da/publications/8f9183cb-47f5-42b5-8721-f4c47f6dfb60
https://doi.org/10.1111/jnc.15754

Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction

Autori: Phillip van Dijck Carmen Hannemann Henryk Dreger a ďalší

Zdroj: J Cardiovasc Transl Res

Predmety: Male, Time Factors, Ventricular Remodeling, Tumor Necrosis Factor-alpha, Myocardial Infarction, Intracellular Signaling Peptides and Proteins, Middle Aged, ADAM17 Protein, Ventricular Function, Left [MeSH], Heart failure, Aged [MeSH], ADAM17 Protein/genetics [MeSH], RNA, Messenger/genetics [MeSH], Tumor Necrosis Factor-alpha/blood [MeSH], Up-Regulation [MeSH], Carrier Proteins/metabolism [MeSH], Original Article, Intracellular Signaling Peptides and Proteins [MeSH], Male [MeSH], Carrier Proteins/genetics [MeSH], Tumor Necrosis Factor-alpha/metabolism [MeSH], Ventricular Dysfunction, Left/blood [MeSH], Ventricular Dysfunction, Left/metabolism [MeSH], RNA, Messenger/metabolism [MeSH], Tumor Necrosis Factor-alpha/genetics [MeSH], Female [MeSH], Ventricular Dysfunction, Left/genetics [MeSH], Carrier Proteins/blood [MeSH], ADAM17 Protein/metabolism [MeSH], Humans [MeSH], Inflammation, Myocardial Infarction/genetics [MeSH], Middle Aged [MeSH], TNF-alpha, Time Factors [MeSH], Ventricular remodeling, Monocytes/metabolism [MeSH], Ventricular Dysfunction, Left/physiopathology [MeSH], iRhom2, Myocardial Infarction/blood [MeSH], Ventricular Remodeling [MeSH], Myocardial infarction, Monocytes, Ventricular Function, Left, Up-Regulation, 3. Good health, Ventricular Dysfunction, Left, Humans, Female, RNA, Messenger, Carrier Proteins, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38743187
https://repository.publisso.de/resource/frl:6523031

3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction

Autori: Erkka Järvinen Helen S. Hammer Oliver Pötz a ďalší

Zdroj: Clinical Pharmacology & Therapeutics. 113:1284-1294

Predmety: Cytochrome P-450 CYP2C8/metabolism, Cells, Cytochrome P-450 Enzyme System/genetics, Carrier Proteins/metabolism, Messenger/metabolism, Cytochrome P-450 CYP2C8, 03 medical and health sciences, 0302 clinical medicine, Liver-Specific Organic Anion Transporter 1/metabolism, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP2C19/metabolism, Humans, Cytochrome P-450 CYP3A, Membrane Transport Proteins/genetics, RNA, Messenger, Cells, Cultured, Cytochrome P-450 CYP2C9, Cultured, Cytochrome P-450 CYP2D6/metabolism, Liver-Specific Organic Anion Transporter 1, Cytochrome P-450 CYP3A/metabolism, Hepatocytes/metabolism, Membrane Transport Proteins, 3. Good health, Cytochrome P-450 CYP2C19, Cytochrome P-450 CYP2C9/metabolism, Cytochrome P-450 CYP2B6, Cytochrome P-450 CYP2D6, Hepatocytes, Cytochrome P-450 CYP2B6/metabolism, RNA, Rifampin, Rifampin/pharmacology, Carrier Proteins

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36906857