Search Results - "Mediation analysis"

Inference in group sequential designs with causal mechanisms: implications for power and mediation analysis.

Authors: Lee KM Emsley R

Source: BMC medical research methodology [BMC Med Res Methodol] 2025 Nov 14; Vol. 25 (1), pp. 257. Date of Electronic Publication: 2025 Nov 14.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968545 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2288 (Electronic) Linking ISSN: 14712288 NLM ISO Abbreviation: BMC Med Res Methodol Subsets: MEDLINE

MeSH Terms: Research Design* , Mediation Analysis*, Humans ; Likelihood Functions ; Causality ; Computer Simulation ; Sample Size ; Bias ; Models, Statistical ; Data Interpretation, Statistical

Estimation of Interventional Effects in Clinical Trials With a Repeatedly Measured Mediator.

Authors: Skov Breum M Sundby Palle M

Source: Statistics in medicine [Stat Med] 2025 Nov; Vol. 44 (25-27), pp. e70305.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print Cited Medium: Internet ISSN: 1097-0258 (Electronic) Linking ISSN: 02776715 NLM ISO Abbreviation: Stat Med Subsets: MEDLINE

MeSH Terms: Randomized Controlled Trials as Topic*/statistics & numerical data , Randomized Controlled Trials as Topic*/methods , Mediation Analysis*, Humans ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/pathology ; Computer Simulation ; Glucagon-Like Peptides/therapeutic use ; Models, Statistical ; Treatment Outcome ; Causality ; Glucagon-Like Peptide 1

Errors-in-variables regression as a viable approach to mediation analysis with random error-tainted measurements: Estimation, effectiveness, and an easy-to-use implementation.

Authors: Hayes AF Allison PD Alexander SM

Source: Behavior research methods [Behav Res Methods] 2025 Oct 29; Vol. 57 (12), pp. 323. Date of Electronic Publication: 2025 Oct 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101244316 Publication Model: Electronic Cited Medium: Internet ISSN: 1554-3528 (Electronic) Linking ISSN: 1554351X NLM ISO Abbreviation: Behav Res Methods Subsets: MEDLINE

MeSH Terms: Mediation Analysis*, Humans ; Regression Analysis ; Bias ; Data Interpretation, Statistical ; Least-Squares Analysis ; Reproducibility of Results ; Models, Statistical ; Computer Simulation

Tutorial on Multiple Mediation Analysis Using Causal Networks: Application to Diagnosing COVID-19 From Its Early and Late Symptoms.

Authors: Alemi F Sandhya Venu V Madduru SCN et al.

Source: Quality management in health care [Qual Manag Health Care] 2025 Oct-Dec 01; Vol. 34 (4), pp. 307-319. Date of Electronic Publication: 2025 Oct 10.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9306156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-5154 (Electronic) Linking ISSN: 10638628 NLM ISO Abbreviation: Qual Manag Health Care Subsets: MEDLINE

MeSH Terms: COVID-19*/diagnosis , COVID-19*/epidemiology , Mediation Analysis*, Humans ; SARS-CoV-2 ; Female ; Male ; Virginia/epidemiology ; Middle Aged ; Adult ; Regression Analysis

Leveraging mediation analysis as a tool to study mechanisms underlying health inequities.

Authors: Rijnhart JJM Bailey RJ Agbodo J et al.

Source: Annals of epidemiology [Ann Epidemiol] 2025 Oct; Vol. 110, pp. 1-6. Date of Electronic Publication: 2025 Jul 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9100013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2585 (Electronic) Linking ISSN: 10472797 NLM ISO Abbreviation: Ann Epidemiol Subsets: MEDLINE

MeSH Terms: Ethnicity*/statistics & numerical data , Health Status Disparities* , Mediation Analysis* , Memory, Episodic*, Aged ; Female ; Humans ; Male ; Middle Aged ; Educational Status ; Hispanic or Latino/statistics & numerical data ; Regression Analysis ; Socioeconomic Factors ; United States/epidemiology ; United States/ethnology

A sensitivity analysis for temporal bias in cross-sectional mediation.

Authors: Georgeson AR Alvarez-Bartolo D MacKinnon DP

Source: Psychological methods [Psychol Methods] 2025 Dec; Vol. 30 (6), pp. 1326-1344. Date of Electronic Publication: 2023 Dec 21.

Publication Type: Journal Article

Journal Info: Publisher: American Psychological Association Country of Publication: United States NLM ID: 9606928 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-1463 (Electronic) Linking ISSN: 1082989X NLM ISO Abbreviation: Psychol Methods Subsets: MEDLINE

MeSH Terms: Models, Statistical* , Psychology*/methods , Mediation Analysis*, Humans ; Cross-Sectional Studies ; Data Interpretation, Statistical ; Bias ; Longitudinal Studies

Association between depressive symptoms and cognitive impairment among older adults in China: a mediation analysis of proactive health.

Authors: Li Y Cheng Z Liu Y et al.

Source: BMC geriatrics [BMC Geriatr] 2025 Nov 18; Vol. 25 (1), pp. 920. Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968548 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2318 (Electronic) Linking ISSN: 14712318 NLM ISO Abbreviation: BMC Geriatr Subsets: MEDLINE

MeSH Terms: Cognitive Dysfunction*/epidemiology , Cognitive Dysfunction*/psychology , Cognitive Dysfunction*/diagnosis , Depression*/epidemiology , Depression*/psychology , Depression*/diagnosis , Mediation Analysis* , Health Status*, Humans ; Male ; Female ; China/epidemiology ; Aged ; Cross-Sectional Studies ; Longitudinal Studies ; Middle Aged ; Aged, 80 and over

Qualitative Mediation Analysis: an Important Method for Exploring Mediating Mechanisms in Prevention Science.

Authors: Kim JJ MacKinnon DP

Source: Prevention science : the official journal of the Society for Prevention Research [Prev Sci] 2025 Nov; Vol. 26 (7), pp. 1076-1086. Date of Electronic Publication: 2025 Aug 23.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 100894724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6695 (Electronic) Linking ISSN: 13894986 NLM ISO Abbreviation: Prev Sci Subsets: MEDLINE

MeSH Terms: Qualitative Research* , Mediation Analysis* , Preventive Medicine*, Humans

High-dimensional causal mediation analysis by partial sum statistic and sample splitting strategy in imaging genetics application.

Authors: Chang HC Fang Y Gorczyca MT et al.

Source: Bioinformatics (Oxford, England) [Bioinformatics] 2025 Oct 02; Vol. 41 (10).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

MeSH Terms: Pulmonary Disease, Chronic Obstructive*/genetics , Pulmonary Disease, Chronic Obstructive*/diagnostic imaging , Computational Biology*/methods , Mediation Analysis*, Humans ; Algorithms

Causal Mediation Analysis with Mediator-outcome Confounders Affected by Exposure: On Definition and Identification of Generalized Natural Indirect Effect.

Authors: Chen YL Yu T Lin SH

Source: Epidemiology (Cambridge, Mass.) [Epidemiology] 2026 Jan 01; Vol. 37 (1), pp. 21-29. Date of Electronic Publication: 2025 Sep 29.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5487 (Electronic) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE

MeSH Terms: Mediation Analysis* , Causality*, Humans ; Confounding Factors, Epidemiologic ; Models, Statistical ; Effect Modifier, Epidemiologic ; Latent Class Analysis

Definition and Interpretation of Separable Path-specific Effects With Multiple Ordered Mediators.

Authors: Chen YL Lin SH

Source: Epidemiology (Cambridge, Mass.) [Epidemiology] 2025 Sep 01; Vol. 36 (5), pp. 677-685. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5487 (Electronic) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE

MeSH Terms: Causality* , Mediation Analysis* , Models, Statistical*, Humans ; Data Interpretation, Statistical

Validation of a Longitudinal Marker as a Surrogate Using Mediation Analysis and Joint Modeling: Evolution of the PSA as a Surrogate of the Disease-Free Survival.

Authors: Le Coent Q Legrand C Dignam JJ et al.

Source: Biometrical journal. Biometrische Zeitschrift [Biom J] 2025 Aug; Vol. 67 (4), pp. e70064.

Publication Type: Journal Article; Validation Study

Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 7708048 Publication Model: Print Cited Medium: Internet ISSN: 1521-4036 (Electronic) Linking ISSN: 03233847 NLM ISO Abbreviation: Biom J Subsets: MEDLINE

MeSH Terms: Prostate-Specific Antigen*/blood , Biometry*/methods , Models, Statistical* , Mediation Analysis*, Humans ; Longitudinal Studies ; Disease-Free Survival ; Male ; Prostatic Neoplasms/blood ; Biomarkers

S-GMAS: Genome-Wide Mediation Analysis With Brain Subcortical Shape Mediators.

Authors: Ding S Liu R Srivastava A et al.

Source: Human brain mapping [Hum Brain Mapp] 2025 Aug 01; Vol. 46 (11), pp. e70297.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 9419065 Publication Model: Print Cited Medium: Internet ISSN: 1097-0193 (Electronic) Linking ISSN: 10659471 NLM ISO Abbreviation: Hum Brain Mapp Subsets: MEDLINE

MeSH Terms: Genome-Wide Association Study*/methods , Brain*/diagnostic imaging , Alzheimer Disease*/genetics , Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/pathology , Neuroimaging*/methods , Mediation Analysis*, Humans ; Polymorphism, Single Nucleotide ; Magnetic Resonance Imaging/methods ; Male

Assessing Mediation in Cross-Sectional Stepped Wedge Cluster Randomized Trials.

Authors: Cao Z Li F

Source: Statistics in medicine [Stat Med] 2025 Jul; Vol. 44 (15-17), pp. e70175.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print Cited Medium: Internet ISSN: 1097-0258 (Electronic) Linking ISSN: 02776715 NLM ISO Abbreviation: Stat Med Subsets: MEDLINE

MeSH Terms: Randomized Controlled Trials as Topic*/methods , Randomized Controlled Trials as Topic*/statistics & numerical data , Mediation Analysis*, Humans ; Linear Models ; Computer Simulation ; Cross-Sectional Studies ; Cluster Analysis ; Models, Statistical

Handling Multivariable Missing Data in Causal Mediation Analysis Estimating Interventional Effects.

Authors: Dashti SG Lee KJ Simpson JA et al.

Source: Epidemiology (Cambridge, Mass.) [Epidemiology] 2025 Jul 01; Vol. 36 (4), pp. 487-499. Date of Electronic Publication: 2025 Apr 01.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5487 (Electronic) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE

MeSH Terms: Mediation Analysis* , Causality*, Humans ; Data Interpretation, Statistical ; Multivariate Analysis ; Bias ; Models, Statistical ; Adolescent ; Confounding Factors, Epidemiologic

Testing measurement and structural invariance in latent mediation models - A comparison of IPCR and Bayesian MNLFA.

Authors: Muench FF Koch T

Source: Behavior research methods [Behav Res Methods] 2025 Aug 08; Vol. 57 (9), pp. 250. Date of Electronic Publication: 2025 Aug 08.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101244316 Publication Model: Electronic Cited Medium: Internet ISSN: 1554-3528 (Electronic) Linking ISSN: 1554351X NLM ISO Abbreviation: Behav Res Methods Subsets: MEDLINE

MeSH Terms: Models, Statistical* , Latent Class Analysis* , Mediation Analysis*, Humans ; Bayes Theorem ; Factor Analysis, Statistical ; Male ; Female

Incorporating small-area estimation into mediation analyses with areal datasets.

Authors: Smith MJ Roberts EK Charlton ME et al.

Source: Spatial and spatio-temporal epidemiology [Spat Spatiotemporal Epidemiol] 2025 Aug; Vol. 54, pp. 100735. Date of Electronic Publication: 2025 Jul 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101516571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-5853 (Electronic) Linking ISSN: 18775845 NLM ISO Abbreviation: Spat Spatiotemporal Epidemiol Subsets: MEDLINE

MeSH Terms: Mediation Analysis* , Small-Area Analysis*, Humans ; Bayes Theorem ; Incidence ; Colorectal Neoplasms/epidemiology ; Computer Simulation ; Datasets as Topic

Causal mediation analysis for time-varying heritable risk factors with Mendelian randomization.

Authors: Wu Z Lewis E Zhao Q et al.

Source: Nature communications [Nat Commun] 2025 Jul 28; Vol. 16 (1), pp. 6945. Date of Electronic Publication: 2025 Jul 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Mendelian Randomization Analysis*/methods , Mediation Analysis*, Humans ; Risk Factors ; Genome-Wide Association Study ; Female ; Body Mass Index ; Breast Neoplasms/genetics ; Breast Neoplasms/epidemiology ; Blood Pressure/genetics ; Causality ; Stroke/genetics ; Stroke/epidemiology ; Genetic Predisposition to Disease ; Cholesterol/blood ; Polymorphism, Single Nucleotide

Bayesian mediation analysis using patient-reported outcomes from AI chatbots to infer causal pathways in clinical trials.

Authors: Shen S Yin J

Source: PloS one [PLoS One] 2025 Jul 24; Vol. 20 (7), pp. e0326517. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Patient Reported Outcome Measures* , Clinical Trials as Topic* , Artificial Intelligence* , Mediation Analysis*, Bayes Theorem ; Humans ; Generative Artificial Intelligence

Natural Effects in the Presence of an Intermediate Confounder: Evaluation of Pragmatic Estimation Strategies With an Emphasis on the Relationship Between Natural and Interventional Effects.

Authors: Gervais J Lefebvre G Moodie EEM

Source: Statistics in medicine [Stat Med] 2025 Jul; Vol. 44 (15-17), pp. e70038.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print Cited Medium: Internet ISSN: 1097-0258 (Electronic) Linking ISSN: 02776715 NLM ISO Abbreviation: Stat Med Subsets: MEDLINE

MeSH Terms: Mediation Analysis*, Humans ; Confounding Factors, Epidemiologic ; Computer Simulation ; Models, Statistical ; Data Interpretation, Statistical ; Causality