Suchergebnisse - "Mechanistic Target of Rapamycin Complex 2/metabolism"

IA Mimétique & Longévité : un injecteur polymorphe pour la science, l'industrie et la société

Autoren: Tabary, Frédéric

Schlagwörter: AMPK, Elastin/immunology, Polyphenols/metabolism, Imagerie cutanée haute résolution, Spermidine, Receptors, AMPA/genetics, Fibrillar Collagens, Spermidine/immunology, Sirtuins/pharmacokinetics, MTOR Inhibitors/isolation & purification, IA dédiée à la Silver Economy, Ceramides/pharmacology, IA au service de l'industrie de la longévité, Mechanistic Target of Rapamycin Complex 2/genetics, Elastin/pharmacokinetics, Elastin/classification, Kinetin/toxicity, Quercetin/pharmacokinetics, Quercetin/genetics, Quercetin/immunology, Peptides/poisoning, Receptors, AMPA/biosynthesis, BeautyTech, Sustainable longevity, Polyphenols/standards, Curcumin/metabolism, MTOR Inhibitors/blood, Receptors, AMPA/history, Peptides/physiology, Organo-on-a-chip, Egg Yolk, Metformin, Longevity-Focused AI, Peptides biomimétiques, Polyphenols/history, Metformin/classification, Normes ISO/IEC 42001, Mechanistic Target of Rapamycin Complex 1/standards, Collagen, Cyclic AMP/economics, Métabolomique, Transcriptomique, MTOR Inhibitors/immunology, Spermidine/urine, Metformin/chemical synthesis, Ceramides/deficiency, Curcumin/analysis, Mechanistic Target of Rapamycin Complex 2/metabolism, NMN (nicotinamide mononucleotide), Ceramides/urine, Egg Shell/parasitology, Metformine, Organoïdes de peau, Jumeaux numériques santé, Elastin/ultrastructure, Kinetin/blood, Sirtuins/blood, Chimie, MTOR Inhibitors/analysis, Biopsie liquide, Ceramides/poisoning, Resveratrol/classification, Quercetin/poisoning, hyaluronique, Egg Hypersensitivity, ΔM11.3 rollback, Polyphenols/economics, MTOR Inhibitors/toxicity, Kinetin/immunology, Polyphenols, Kinetin/biosynthesis, Santé cellulaire, Fisetin, Vieillissement actif, Elastin, Elastin/toxicity, Sirtuins/chemistry, IA de pointe pour la santé et la longévité, Kinetin/history, Neuro-immuno-dermatologie, Metformin/pharmacokinetics, Resveratrol, Metformin/agonists, Céramides, Receptors, AMPA/analysis, Metformin/standards, Mechanistic Target of Rapamycin Complex 2/analysis, Peptides, Sirtuins/pharmacology, Receptors, AMPA/agonists, Sirtuins/biosynthesis, Quercetin/pharmacology, Sirtuins/economics, NR (nicotinamide riboside), Metformin/blood, Peptides/metabolism, Metformin/metabolism, Egg Shell, IA mimetique, Peptides/history, MTOR Inhibitors/pharmacokinetics, Metformin/pharmacology, Egg Proteins/immunology, Polyphenols/genetics, Épigénomique, Metformin/cerebrospinal fluid, Receptors, AMPA/classification, Metformin/toxicity, IA appliquée aux sciences du vieillissement, Peptides/urine, Curcumin/therapeutic use, Peptides/deficiency, Cyclic AMP/chemistry, Cyclic AMP/pharmacology, Quercetin/blood, Nutraceutiques, IA computationnelle en biologie du vieillissement, Collagen/immunology, Peptides/pharmacokinetics, Healthspan vs Lifespan, Ceramides/genetics, Receptors, AMPA/chemistry, Peptides/analysis, MTOR Inhibitors, Quercetin/history, IA biomédicale pour la longévité, HyperGlottal, Metformin/economics, Peptides/immunology, Ceramides/economics, Smart Longevity AI, Quercetin, MTOR Inhibitors/chemical synthesis, Quercetin/economics, Ceramides/classification, Polyphenols/biosynthesis, Polyphenols/pharmacology, Antimicrobial Peptides, Open source AI, Receptors, Collagen, Polyphenols/classification, Quercetin/metabolism, Elastin/physiology, IA éthique appliquée à la santé, Curcumin/administration & dosage, Polyphenols/poisoning, Chronobiologie & horloges circadiennes, Collagen/blood, Quercetin/radiation effects, RGPD, Receptors, AMPA/metabolism, Spermidine Synthase, Kinetin/urine, Curcumin/radiation effects, Peptides/economics, Quercetin/physiology, Elastin/metabolism, Ceramides/biosynthesis, Microbiome cutané, Kinetin/classification, Rapamycine, Polyphenols/urine, Polyphenols/chemistry, Quercétine, Curcumin/analogs & derivatives, Receptors, AMPA/physiology, Curcumine, Natriuretic Peptides, PolyResonator, Quercetin/biosynthesis, Collagen/economics, Ceramides/agonists, CRISPR/Cas9, Collagen/deficiency, Transparence, AI for Lifespan & Healthspan, Quercetin/toxicity, Mechanistic Target of Rapamycin Complex 1/chemistry, Curcumin/pharmacology, Polyphenols/agonists, Santé préventive, Sirtuins/immunology, Analyse de télomères, Rapamycin-Insensitive Companion of mTOR Protein, Innovation responsable, Kinetin/agonists, Spermidine/agonists, Collagen/toxicity, Elastin/standards, Healthspan, Coenzyme Q10, Kinetin/analysis, Elastin/biosynthesis, Elastin/pharmacology, Egg Shell/immunology, Tarification éthique, Peptides/genetics, Sirtuins/analysis, Elastin/blood, Isatin, Ceramides/analysis, Acide hyaluronique, Collagen/standards, VEX, Kinetin/pharmacology, Rapamycin-Insensitive Companion of mTOR Protein/deficiency, MTOR Inhibitors/standards, Curcumin/supply & distribution, Rapamycin-Insensitive Companion of mTOR Protein/biosynthesis, Sirtuins/genetics, Rapamycin-Insensitive Companion of mTOR Protein/standards, Polyphenols/analysis, MTOR Inhibitors/history, Resveratrol/blood, Rapamycin-Insensitive Companion of mTOR Protein/metabolism, AMP Deaminase, MTOR Inhibitors/metabolism, Protéomique, Loreal, Curcumin/standards, MTOR Inhibitors/therapeutic use, MTOR Inhibitors/urine, Compliance AI, Sirtuins/deficiency, MTOR Inhibitors/chemistry, Peptides/pharmacology, MTOR Inhibitors/pharmacology, Collagen/pharmacokinetics, Spermidine/pharmacokinetics, Curcumin/chemical synthesis, IA multi-omique pour la longévité, Polyphénols, Data sovereignty, Sirtuins/classification, Microbiome cutané & intestinal, Elastin/chemistry, Collagen/urine, Reproducibility, Oxydation protéines/lipides, Collagène, Sirtuins/urine, Resveratrol/metabolism, Opioid Peptides, Rapamycin-Insensitive Companion of mTOR Protein/pharmacokinetics, RGPD santé, AI for Longevity Science, Injecteur polymorphe, Société du vieillissement, Collagen/chemistry, Receptors, AMPA/blood, Curcumin/isolation & purification, IA prédictive multi-omique, Mechanistic Target of Rapamycin Complex 2/toxicity, Ceramides/chemistry, Receptors, AMPA/ultrastructure, Ceramides, Kinetin/genetics, Polyprenols, Sirtuins/physiology, Resvératrol, Kinetin/standards, AI for Healthy Aging, Curcumin/economics, IA appliquée aux biotechnologies du vieillissement, Egg White, Polyphenols/immunology, AI Act, Silver economy, Egg, Polyphenols/blood, Longevite, Quercetin/chemistry, Collagen/classification, AI Act Compliance, MTOR Inhibitors/poisoning, IA translationnelle en gérontologie, Sirtuins/metabolism, Épigénétique, Egg Proteins, Metformin/analysis, Mechanistic Target of Rapamycin Complex 2/urine, Ceramides/blood, Peptides/toxicity, Kinetin, Elastin/analysis, MTOR Inhibitors/administration & dosage, Ceramides/immunology, Egg Shell/chemistry, Sirtuins/poisoning, Egg Shell/abnormalities, C2PA, Cobamides, Mechanistic Target of Rapamycin Complex 1/metabolism, Sirtuins/history, EGCG, Standards inclusifs, Egg Shell/cytology, Elastin/agonists, Mechanistic Target of Rapamycin Complex 1/deficiency, Metformin/isolation & purification, Quercetin/urine, Resveratrol/standards, Egg Proteins/history, Collagen/analysis, Peptides/chemistry, Egg Proteins/urine, Spermidine/classification, Receptors, AMPA/immunology, Ceramides/pharmacokinetics, Kinetin/physiology, Polyphenols/physiology, Cyclic AMP, Sirtuins, Peptides/standards, Suppléments longévité, Curcumin/pharmacokinetics, Biomarqueurs, Elastin/urine, MTOR Inhibitors/classification, Ceramides/physiology, Kinetin/pharmacokinetics, Metformin/immunology, IA dédiée à la recherche en longévité, Metformin/urine, Egg Proteins/pharmacokinetics, Collagen/physiology, Sirtuins/ultrastructure, NAD⁺ (nicotinamide adenine dinucleotide), Elastin/poisoning, Next-Gen Longevity AI, mTOR, Sex, Resveratrol/economics, Ceramides/history, Gouvernance IA, Egg Shell/embryology, Collagen/poisoning, Curcumin, Coenzyme Q10 (CoQ10, Ubiquinone), Elastin/genetics, Sirtuins/standards, Élastine, Quercetin/agonists, Receptors, AMPA/deficiency, Metformin/chemistry, NR, Mechanistic Target of Rapamycin Complex 2, Mechanistic Target of Rapamycin Complex 1, Collagen/biosynthesis, Cosmétiques anti-âge, Vieillissement, Peptides, Cyclic, Cyclic AMP/history, Polyphenols/pharmacokinetics, Curcumin/toxicity, Ceramides/metabolism, CycloneDX SBOM, Sirtuins/toxicity, Kinetin/metabolism, Quercetin/classification, Mechanistic Target of Rapamycin Complex 1/pharmacology, Receptors, AMPA, Normes éthiques, Curcumin/adverse effects, Kinetin/chemistry, Mechanistic Target of Rapamycin Complex 2/classification, Collagen/agonists, Collagen Diseases, Quercetin/standards, Polyphenols/toxicity, Spermidine/metabolism, MTOR Inhibitors/cerebrospinal fluid, Ceramides/standards, EthicChain, Curcumin/classification, Quercetin/analysis, Spermidine/pharmacology, Curcumin/poisoning, Metformin/antagonists & inhibitors, MTOR Inhibitors/economics, Kinetin/poisoning, Egg Proteins/pharmacology, Curcumin/chemistry, Sirtuines

Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapy: biology and implication for therapy

Autoren: Wang, Yanmeng Vandewalle, Niels De Veirman, Kim et al.

Weitere Verfasser: Wang, Yanmeng Vandewalle, Niels De Veirman, Kim et al.

Quelle: Cell Commun Signal
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)

Schlagwörter: 0301 basic medicine, TOR Serine-Threonine Kinases/metabolism, Mechanistic Target of Rapamycin Complex 2/metabolism, Review, Mechanistic Target of Rapamycin Complex 2, Targeted therapy, 03 medical and health sciences, Multiple myeloma, Signal Transduction/drug effects, MTOR Inhibitors/therapeutic use, Humans, Animals, Molecular Targeted Therapy, Multiple Myeloma/metabolism, 0303 health sciences, QH573-671, TOR Serine-Threonine Kinases, MTOR Inhibitors, 3. Good health, mTOR, Medicine, Protein synthesis, Cytology, Multiple Myeloma, Signal Transduction

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38862983
https://doaj.org/article/e5bf627c82af4b75bb7d189ce17c47ad
https://biblio.vub.ac.be/vubir/(eb577601-fb2d-4761-a086-7439efe3caa0).html

Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8 + T Cells.

Autoren: Bantug, G.R. Fischer, M. Grählert, J. et al.

Schlagwörter: CD8-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/metabolism, Cell Respiration, Endoplasmic Reticulum/metabolism, Endoplasmic Reticulum/ultrastructure, Energy Metabolism, Glycogen Synthase Kinase 3 beta/metabolism, Glycolysis, Immunologic Memory, Intracellular Membranes/metabolism, Lymphocyte Activation, Mechanistic Target of Rapamycin Complex 2/metabolism, Mitochondria/metabolism, Mitochondria/ultrastructure, Models, Biological, Proto-Oncogene Proteins c-akt/metabolism, Rapamycin-Insensitive Companion of mTOR Protein/deficiency, Signal Transduction, Akt, GSK3-beta, IFN-gamma, VDAC, endoplasmic reticulum, hexokinase, mTOR, memory CD8(+) T cells, mitochondria

Relation: Immunity; https://iris.unil.ch/handle/iris/175757; serval:BIB_860F1556AA95; 000427916900014

Verfügbarkeit: https://iris.unil.ch/handle/iris/175757
https://doi.org/10.1016/j.immuni.2018.02.012

WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport

Autoren: Bidisha Saha Deise C. A. Leite-Dellova John Demko et al.

Quelle: J Cell Sci
Saha, B, Leite-Dellova, D C A, Demko, J, Sørensen, M V, Takagi, E, Gleason, C E, Shabbir, W & Pearce, D 2022, 'WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport', Journal of Cell Science, vol. 135, no. 23, jcs260313. https://doi.org/10.1242/jcs.260313

Schlagwörter: 0301 basic medicine, Epithelial Sodium Channels/genetics, ENaC, Chlorides/metabolism, K+ homeostasis, Mechanistic Target of Rapamycin Complex 2/metabolism, TOR Serine-Threonine Kinases/metabolism, Mechanistic Target of Rapamycin Complex 2, Protein Serine-Threonine Kinases, Rictor, Immediate-Early Proteins, Minor Histocompatibility Antigens, Electrolytes, 03 medical and health sciences, Minor Histocompatibility Antigens/genetics, Chlorides, Animals, Kidney epithelial cells, SGK1, WNK1, Epithelial Sodium Channels, mTORC2, Ion transport, Mammals, 0303 health sciences, Ion Transport, Mammals/metabolism, WNK kinase, TOR Serine-Threonine Kinases, Immediate-Early Proteins/genetics, Protein–protein interaction, mTOR, Research Article

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36373794
https://pure.au.dk/portal/en/publications/9c8ebebb-8bdf-4b00-92ed-ba72d8c3ec66