Výsledky vyhľadávania - "MYOFIBROBLASTS"

Characterisation of the tumour microenvironment and PD-L1 granularity reveals the prognostic value of cancer-associated myofibroblasts in non-invasive bladder cancer.

Autori: Cañizo CG Guerrero-Ramos F Perez Escavy M a ďalší

Zdroj: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2438291. Date of Electronic Publication: 2024 Dec 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/metabolism , Urinary Bladder Neoplasms*/immunology , Urinary Bladder Neoplasms*/genetics , Tumor Microenvironment*/immunology , B7-H1 Antigen*/metabolism , B7-H1 Antigen*/genetics , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics, Humans ; Male ; Prognosis ; Female ; Aged ; Middle Aged ; Cancer-Associated Fibroblasts/metabolism ; Cancer-Associated Fibroblasts/pathology ; Prospective Studies ; Aged, 80 and over ; Macrophages/metabolism ; Macrophages/immunology ; Macrophages/pathology

Insights into the Cellular and Molecular Mechanisms behind the Antifibrotic Effects of Nerandomilast.

Autori: Reininger D Wolf F Mayr CH a ďalší

Zdroj: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Nov; Vol. 73 (5), pp. 700-712.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Myofibroblasts*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Antifibrotic Agents*/pharmacology, Humans ; Animals ; Mice ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Lung/drug effects ; Lung/pathology ; Lung/metabolism ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Signal Transduction/drug effects ; Disease Models, Animal ; Capillary Permeability/drug effects

Targeting microRNA-132 protects against kidney fibrosis and restricts myofibroblast differentiation from cells of renin lineage.

Autori: van der Pluijm LAK Koudijs A Duijs JMGJ a ďalší

Zdroj: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2025 Nov 01; Vol. 329 (5), pp. C1429-C1438. Date of Electronic Publication: 2025 Sep 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Renin*/genetics , Renin*/metabolism , Cell Differentiation*/genetics , Kidney*/pathology , Kidney*/metabolism, Animals ; Fibrosis ; Mice ; Cell Lineage ; Male ; Mice, Inbred C57BL ; Podocytes/metabolism ; Podocytes/pathology ; Cell Proliferation ; Disease Models, Animal ; Reperfusion Injury/pathology ; Reperfusion Injury/genetics ; Reperfusion Injury/metabolism

Targeted delivery of Bak BH3 peptide to renal myofibroblast for renal fibrosis treatment by activating the mitochondrial-dependent apoptosis pathway.

Autori: Wang X Xu L Kong L a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Oct 30; Vol. 164, pp. 115324. Date of Electronic Publication: 2025 Aug 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/drug effects , Myofibroblasts*/metabolism , Mitochondria*/metabolism , Mitochondria*/drug effects , Kidney*/pathology , Kidney*/drug effects , Kidney Diseases*/drug therapy , Kidney Diseases*/pathology , Peptide Fragments*/therapeutic use , bcl-2 Homologous Antagonist-Killer Protein*/genetics, Animals ; Apoptosis/drug effects ; Mice ; NIH 3T3 Cells ; Fibrosis/drug therapy ; Male ; Humans ; Disease Models, Animal ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Receptor, Platelet-Derived Growth Factor beta/genetics ; Mice, Inbred C57BL ; Proto-Oncogene Proteins

Runx1 drives cardiac fibrosis and heart failure through epigenetic activation of myofibroblasts in pressure overload-induced cardiac remodeling.

Autori: An J Zhou W Xia L a ďalší

Zdroj: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2025 Oct 21; Vol. 25 (1), pp. 746. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Myofibroblasts*/drug effects , Core Binding Factor Alpha 2 Subunit*/genetics , Core Binding Factor Alpha 2 Subunit*/metabolism , Core Binding Factor Alpha 2 Subunit*/deficiency , Heart Failure*/metabolism , Heart Failure*/genetics , Heart Failure*/physiopathology , Heart Failure*/pathology , Ventricular Remodeling* , Epigenesis, Genetic* , Myocardium*/pathology , Myocardium*/metabolism , Ventricular Function, Left*, Animals ; Fibrosis ; Disease Models, Animal ; Mice, Knockout ; Cells, Cultured ; Male ; Mice, Inbred C57BL ; Signal Transduction ; Acetylation ; Histones/metabolism ; Mice ; Cell Adhesion Molecules

Platelet Polyphosphate Signals Through NFκB to Induce Myofibroblast Differentiation.

Autori: Suess PM La CC Vappala S a ďalší

Zdroj: Biomolecules [Biomolecules] 2025 Oct 12; Vol. 15 (10). Date of Electronic Publication: 2025 Oct 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/metabolism , Myofibroblasts*/cytology , Myofibroblasts*/drug effects , NF-kappa B*/metabolism , Cell Differentiation*/drug effects , Polyphosphates*/metabolism , Polyphosphates*/pharmacology , Blood Platelets*/metabolism, Humans ; Animals ; Mice ; Signal Transduction/drug effects ; NIH 3T3 Cells ; Wound Healing ; Receptor for Advanced Glycation End Products/metabolism

Stathmin-mediated autophagy drives the differentiation of dermal fibroblast into myofibroblast under TGFβ1 stimulation.

Autori: Tang H Yang L Feng Y a ďalší

Zdroj: Molecular biology reports [Mol Biol Rep] 2025 Dec 06; Vol. 53 (1), pp. 166. Date of Electronic Publication: 2025 Dec 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Autophagy*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/cytology , Myofibroblasts*/drug effects , Transforming Growth Factor beta1*/metabolism , Transforming Growth Factor beta1*/pharmacology , Stathmin*/metabolism , Stathmin*/genetics , Fibroblasts*/metabolism , Fibroblasts*/cytology , Fibroblasts*/drug effects, Cell Differentiation/drug effects ; Humans ; Skin/cytology ; Skin/metabolism ; Wound Healing ; p38 Mitogen-Activated Protein Kinases/metabolism ; Dermis/cytology ; Dermis/metabolism ; Cells, Cultured

Corneal Myofibroblasts Suppress T-Cell Immunity in Corneal Transplantation.

Autori: Wang S Esquivel Herrera A Elbasiony E a ďalší

Zdroj: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Dec 01; Vol. 66 (15), pp. 2.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/immunology , Myofibroblasts*/physiology , Corneal Transplantation* , Cornea*/immunology , Cornea*/cytology , T-Lymphocytes*/immunology, Animals ; Mice ; Coculture Techniques ; Mice, Inbred C57BL ; Flow Cytometry ; Apoptosis ; Lymphocyte Activation/immunology ; Cell Proliferation ; Interferon-gamma/metabolism ; Mice, Inbred BALB C ; Cells, Cultured ; Fibroblasts ; CD40 Ligand/metabolism ; Antigens, CD/metabolism

Myofibroblast specific knockdown of NSUN2 suppresses cardiac fibrosis post-myocardial infarction.

Autori: Sun Z Li N Huang M a ďalší

Zdroj: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2025 Dec; Vol. 209, pp. 27-36. Date of Electronic Publication: 2025 Oct 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Myocardial Infarction*/pathology , Myocardial Infarction*/genetics , Myocardial Infarction*/complications , Myocardial Infarction*/metabolism , Methyltransferases*/genetics , Methyltransferases*/metabolism , Myocardium*/pathology , Myocardium*/metabolism , Gene Knockdown Techniques*, Fibrosis ; Animals ; ELAV-Like Protein 1/metabolism ; ELAV-Like Protein 1/genetics ; Mice ; RNA Stability ; Male ; Humans ; Disease Models, Animal ; Mice, Inbred C57BL

Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.

Autori: Dong RH Li X Yue HH a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 2), pp. 117283. Date of Electronic Publication: 2025 Aug 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/chemically induced , Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology , Myofibroblasts*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/pathology, Animals ; Humans ; Mice ; Bleomycin/toxicity ; Male ; Mice, Inbred C57BL ; Female ; Cells, Cultured ; Lung/drug effects ; Lung/pathology ; Cell Differentiation/drug effects

HIF-1α/A2BAR signalling pathway alleviates kidney fibrosis after ischemia-reperfusion injury by preventing macrophage-to-myofibroblast transition.

Autori: Yang Y Tao T Huang J a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 2), pp. 117358. Date of Electronic Publication: 2025 Sep 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Reperfusion Injury*/metabolism , Reperfusion Injury*/pathology , Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism , Hypoxia-Inducible Factor 1, alpha Subunit*/genetics , Macrophages*/metabolism , Macrophages*/pathology , Macrophages*/drug effects , Receptor, Adenosine A2B*/metabolism , Receptor, Adenosine A2B*/genetics , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Myofibroblasts*/drug effects , Kidney*/pathology , Kidney*/metabolism, Animals ; Fibrosis/metabolism ; Signal Transduction/physiology ; Signal Transduction/drug effects ; Mice ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Acute Kidney Injury/metabolism ; Acute Kidney Injury/pathology

Human breast milk as a bioactive material platform enabling scarless skin regeneration via macrophage reprogramming and myofibroblast heterogeneity.

Autori: Xian C Gu Z Wu J

Zdroj: Materials horizons [Mater Horiz] 2025 Nov 25; Vol. 12 (23), pp. 10157-10169. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101623537 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-6355 (Electronic) Linking ISSN: 20516347 NLM ISO Abbreviation: Mater Horiz Subsets: MEDLINE

Výrazy zo slovníka MeSH: Macrophages*/metabolism , Macrophages*/cytology , Macrophages*/drug effects , Milk, Human*/chemistry , Milk, Human*/metabolism , Skin*/injuries , Myofibroblasts*/metabolism , Myofibroblasts*/cytology , Regeneration*/drug effects , Biocompatible Materials*/pharmacology , Biocompatible Materials*/chemistry, Humans ; Animals ; Wound Healing/drug effects ; Mice ; Female ; Cicatrix ; Hydrogels/chemistry ; Cellular Reprogramming/drug effects

TNF-α represses fibroblast to myofibroblast transition through the histone methyltransferase Setdb2.

Autori: Bauer TM Mangum KD Buckley SD a ďalší

Zdroj: JCI insight [JCI Insight] 2025 Nov 24; Vol. 10 (22). Date of Electronic Publication: 2025 Nov 24 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Tumor Necrosis Factor-alpha*/metabolism , Fibroblasts*/metabolism , Histone-Lysine N-Methyltransferase*/metabolism , Histone-Lysine N-Methyltransferase*/genetics , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/pathology, Animals ; Humans ; Mice ; Signal Transduction ; Wound Healing ; STAT3 Transcription Factor/metabolism ; Mice, Transgenic ; Male ; Janus Kinase 1/metabolism ; Mice, Inbred C57BL

Clinicopathological Features and Immunochemical Staining of Inflammatory Myofibroblastic Tumor: A Retrospective Study of 48 Cases.

Autori: Wang QA Wu RC Lee CW a ďalší

Zdroj: Analytical cellular pathology (Amsterdam) [Anal Cell Pathol (Amst)] 2025 Nov 18; Vol. 2025, pp. 4948627. Date of Electronic Publication: 2025 Nov 18 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley and Sons Country of Publication: United States NLM ID: 101541993 Publication Model: eCollection Cited Medium: Internet ISSN: 2210-7185 (Electronic) Linking ISSN: 22107177 NLM ISO Abbreviation: Anal Cell Pathol (Amst) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms, Muscle Tissue*/pathology , Neoplasms, Muscle Tissue*/metabolism , Myofibroblasts*/pathology , Myofibroblasts*/metabolism , Inflammation*/pathology, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Immunohistochemistry ; Anaplastic Lymphoma Kinase/metabolism ; Aged ; Young Adult ; Adolescent ; Child

Epigenetic Reprogramming Via Sodium Butyrate Induces Corneal Myofibroblast Dedifferentiation In Vitro and Inhibits Fibrosis In Vivo.

Autori: Sood S Sinha NR Tiwari A a ďalší

Zdroj: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Nov 03; Vol. 66 (14), pp. 59.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myofibroblasts*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Butyric Acid*/pharmacology , Epigenesis, Genetic*/drug effects , Cell Dedifferentiation*/drug effects , Cornea*/pathology , Cornea*/drug effects , Cornea*/metabolism , Corneal Diseases*/pathology , Corneal Diseases*/genetics , Corneal Diseases*/metabolism , Corneal Diseases*/prevention & control, Rabbits ; Animals ; Humans ; Fibrosis/prevention & control ; Cells, Cultured ; Disease Models, Animal ; Histone Deacetylase Inhibitors/pharmacology ; DNA Methylation ; Real-Time Polymerase Chain Reaction ; S100 Calcium-Binding Protein A4

PRRX1 Orchestrates Pericyte-Myofibroblast Transition in Pathological Retinal Fibrosis.

Autori: Meng Z Liu D Hu Y a ďalší

Zdroj: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Nov 03; Vol. 66 (14), pp. 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pericytes*/metabolism , Pericytes*/pathology , Homeodomain Proteins*/genetics , Homeodomain Proteins*/biosynthesis , Homeodomain Proteins*/physiology , Myofibroblasts*/pathology , Myofibroblasts*/metabolism , Retinal Diseases*/pathology , Retinal Diseases*/metabolism , Retinal Diseases*/genetics , Retina*/pathology , Retina*/metabolism , Gene Expression Regulation*/physiology, Animals ; Mice ; Fibrosis/metabolism ; Fibrosis/pathology ; Humans ; Mice, Inbred C57BL ; Disease Models, Animal ; Cells, Cultured ; Cell Movement ; Gene Expression Profiling ; Male

Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis.

Autori: Kim MJ Park SB Hwang HS a ďalší

Zdroj: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2025 Nov; Vol. 205, pp. 115705. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pulmonary Fibrosis*/chemically induced , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism , Myofibroblasts*/drug effects , Myofibroblasts*/cytology , Fibroblasts*/drug effects , Fibroblasts*/cytology , Fibroblasts*/metabolism , Guanidines*/toxicity, Humans ; Animals ; Rats ; Reactive Oxygen Species/metabolism ; Cell Differentiation/drug effects ; Transforming Growth Factor beta1/metabolism ; Transforming Growth Factor beta1/genetics ; Rats, Sprague-Dawley ; Cell Line ; Male ; Cell Movement/drug effects ; Extracellular Matrix/metabolism ; Extracellular Matrix/drug effects

Radiation Induces Pericyte-Myofibroblast Transition.

Autori: Yamazaki T Jordan KR Fox N a ďalší

Zdroj: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Nov 01; Vol. 123 (3), pp. 860-875. Date of Electronic Publication: 2025 Jun 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pericytes*/radiation effects , Pericytes*/cytology , Pericytes*/metabolism , Myofibroblasts*/radiation effects , Myofibroblasts*/cytology , Myofibroblasts*/metabolism , Cell Differentiation*/radiation effects, Animals ; Mice ; Humans ; Reactive Oxygen Species/metabolism ; Female ; Mice, Transgenic ; Signal Transduction/radiation effects ; Pregnancy ; Placenta/cytology ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Vimentin/metabolism

Matrix Softness Induces an Afibrogenic Lipofibroblast Phenotype in Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis.

Autori: Berhan A Gunatilaka A Lee C a ďalší

Zdroj: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Nov; Vol. 73 (5), pp. 686-699.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Myofibroblasts*/metabolism , Myofibroblasts*/pathology , Myofibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology, Humans ; Transforming Growth Factor beta1/pharmacology ; Transforming Growth Factor beta1/metabolism ; Phenotype ; Cell Differentiation ; Cells, Cultured ; YAP-Signaling Proteins ; Adaptor Proteins, Signal Transducing/metabolism ; Actins/metabolism ; Signal Transduction

Structure-Activity Relationships of N -Acyl Dopamines in Inhibiting Myofibroblast Transdifferentiation of Retinal Pigment Epithelial Cells.

Autori: Zhao D Motheramgari V Freudenberger R a ďalší

Zdroj: Biomolecules [Biomolecules] 2025 Oct 30; Vol. 15 (11). Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cell Transdifferentiation*/drug effects , Retinal Pigment Epithelium*/cytology , Retinal Pigment Epithelium*/drug effects , Retinal Pigment Epithelium*/metabolism , Myofibroblasts*/drug effects , Myofibroblasts*/cytology , Myofibroblasts*/metabolism , Dopamine*/pharmacology , Dopamine*/analogs & derivatives , Dopamine*/chemistry, Humans ; Structure-Activity Relationship ; Animals ; Swine ; Cells, Cultured