Suchergebnisse - "MUCINS"

Immunomodulatory properties of transmembrane mucins: from chronic diseases to cancer.

Autoren: Montero P Roger I Milara J et al.

Quelle: Physiological reviews [Physiol Rev] 2025 Oct 01; Vol. 105 (4), pp. 2233-2304. Date of Electronic Publication: 2025 Jun 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0231714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1210 (Electronic) Linking ISSN: 00319333 NLM ISO Abbreviation: Physiol Rev Subsets: MEDLINE

MeSH-Schlagworte: Mucins*/metabolism , Mucins*/immunology , Mucins*/genetics , Neoplasms*/immunology , Neoplasms*/metabolism , Immunomodulation*, Humans ; Chronic Disease ; Animals

MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus Metarhizium acridum .

Autoren: Dai H Wen Z Xia Y et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2541708. Date of Electronic Publication: 2025 Aug 02.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Metarhizium*/pathogenicity , Metarhizium*/genetics , Metarhizium*/growth & development , Metarhizium*/physiology , Spores, Fungal*/growth & development , Spores, Fungal*/genetics , Fungal Proteins*/genetics , Fungal Proteins*/metabolism , Mucins*/genetics , Mucins*/metabolism , Stress, Physiological*, Virulence ; Animals ; Gene Expression Regulation, Fungal ; Grasshoppers/microbiology ; Gene Knockout Techniques ; Signal Transduction

SCR Organism: Metarhizium acridum

Cryptosporidium exports a mucin glycoprotein into the microvilli of intestinal epithelium.

Autoren: Xu R Li J Wu W et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2553780. Date of Electronic Publication: 2025 Sep 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Mucins*/metabolism , Mucins*/genetics , Protozoan Proteins*/metabolism , Protozoan Proteins*/genetics , Intestinal Mucosa*/parasitology , Intestinal Mucosa*/metabolism , Microvilli*/metabolism , Microvilli*/parasitology , Cryptosporidium parvum*/genetics , Cryptosporidium parvum*/metabolism , Cryptosporidium parvum*/pathogenicity, Animals ; Mice ; Humans ; Cryptosporidiosis/parasitology ; Sporozoites/metabolism ; Protein Transport

From slime to sublime: the impact of snail mucin on scar therapy and wound healing in dermatology.

Autoren: Sekar D Nagarajan P Ekambaram G et al.

Quelle: Cutaneous and ocular toxicology [Cutan Ocul Toxicol] 2025 Dec; Vol. 44 (4), pp. 409-412. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101266892 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-9535 (Electronic) Linking ISSN: 15569527 NLM ISO Abbreviation: Cutan Ocul Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Wound Healing*/drug effects , Cicatrix*/drug therapy , Mucins*/therapeutic use , Mucins*/pharmacology , Mucins*/adverse effects, Humans ; Animals ; Snails/chemistry ; Dermatology

Treatment with (R)-α-methylhistamine or IL4 stimulates mucin production and decreases Helicobacter pylori density in the murine stomach.

Autoren: Santos L Sharba S Benktander J et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2530173. Date of Electronic Publication: 2025 Jul 16.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Helicobacter pylori*/drug effects , Helicobacter pylori*/growth & development , Helicobacter Infections*/drug therapy , Helicobacter Infections*/microbiology , Interleukin-4*/pharmacology , Interleukin-4*/administration & dosage , Mucins*/biosynthesis , Mucins*/metabolism , Stomach*/microbiology, Animals ; Mice, Inbred C57BL ; Male ; Mice ; Gastric Mucosa/microbiology ; Disease Models, Animal ; Bacterial Load/drug effects

Disease-specific alterations of the enteric nervous system in precancerous colonic mucosa and their implications for mucin regulation.

Autoren: Imura T Miyagawa-Hayashino A Honda M et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40719. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Enteric Nervous System*/pathology , Enteric Nervous System*/metabolism , Intestinal Mucosa*/pathology , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/innervation , Mucins*/metabolism , Mucins*/genetics , Precancerous Conditions*/pathology , Precancerous Conditions*/metabolism , Colonic Neoplasms*/pathology , Colonic Neoplasms*/metabolism , Colon*/pathology , Colon*/innervation , Colon*/metabolism, Humans ; Female ; Male ; Middle Aged ; Aged ; Neuroglia/metabolism ; Neuroglia/pathology ; Vasoactive Intestinal Peptide/metabolism ; Adult ; Neurites/metabolism ; Neurites/pathology ; Adenoma/pathology ; Adenoma/metabolism ; SOXE Transcription Factors/metabolism

CAR-T cell therapy targeting MUC17 in gastric tumors.

Autoren: Park S Ho CE Birocchi F et al.

Quelle: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Nov 18; Vol. 13 (11). Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

MeSH-Schlagworte: Stomach Neoplasms*/therapy , Stomach Neoplasms*/immunology , Stomach Neoplasms*/pathology , Immunotherapy, Adoptive*/methods , Receptors, Chimeric Antigen*/metabolism , Mucins*/immunology , Mucins*/metabolism, Humans ; Animals ; Mice ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Female

Heat-Induced Structural Changes in Lactoferrin for Enhanced Mucoadhesion.

Autoren: Hazt B Read DJ Harlen OG et al.

Quelle: ACS applied bio materials [ACS Appl Bio Mater] 2025 Nov 17; Vol. 8 (11), pp. 10255-10271. Date of Electronic Publication: 2025 Oct 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ACS Publications Country of Publication: United States NLM ID: 101729147 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-6422 (Electronic) Linking ISSN: 25766422 NLM ISO Abbreviation: ACS Appl Bio Mater Subsets: MEDLINE

MeSH-Schlagworte: Lactoferrin*/chemistry , Biocompatible Materials*/chemistry , Mucins*/chemistry , Mucins*/metabolism, Hot Temperature ; Materials Testing ; Humans ; Adhesiveness ; Hydrophobic and Hydrophilic Interactions ; Animals ; Particle Size

Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency.

Autoren: Yu J Wang Y Liu Q et al.

Quelle: MBio [mBio] 2025 Nov 12; Vol. 16 (11), pp. e0205525. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

MeSH-Schlagworte: Herpesvirus 4, Human*/physiology , Herpesvirus 4, Human*/genetics , Virus Latency*/genetics , Mucins*/genetics , Mucins*/metabolism, Humans ; DNA Copy Number Variations ; Epstein-Barr Virus Infections/virology ; Epstein-Barr Virus Infections/genetics ; B-Lymphocytes/virology ; Genetic Variation ; Host-Pathogen Interactions ; Chromosome Mapping ; Whole Genome Sequencing

Intestinal Mucin Glycosylation: Structural Regulation, Homeostasis Maintenance and Disease Association.

Autoren: Li Y Pan J Liu H et al.

Quelle: Biomolecules [Biomolecules] 2025 Nov 05; Vol. 15 (11). Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH-Schlagworte: Mucins*/metabolism , Mucins*/chemistry , Homeostasis* , Intestinal Mucosa*/metabolism, Humans ; Glycosylation ; Animals ; Gastrointestinal Microbiome

Mucin-producing cystic hepatobiliary neoplasms: Key diagnostic information for radiologists.

Autoren: Berbel Rodríguez A García-Baizán A Frade-Santos S et al.

Quelle: Radiologia [Radiologia (Engl Ed)] 2025 Nov-Dec; Vol. 67 (6), pp. 101568. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier España Country of Publication: Spain NLM ID: 101770876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2173-5107 (Electronic) Linking ISSN: 21735107 NLM ISO Abbreviation: Radiologia (Engl Ed) Subsets: MEDLINE

MeSH-Schlagworte: Liver Neoplasms*/metabolism , Liver Neoplasms*/diagnostic imaging , Bile Duct Neoplasms*/diagnostic imaging , Bile Duct Neoplasms*/metabolism , Mucins*/metabolism , Mucins*/biosynthesis, Humans ; Female ; Male ; Middle Aged ; Aged

The clinicopathological characteristics and prognosis of mucin-laden nonmucinous lung adenocarcinoma.

Autoren: Yang F Guo J Yang Z et al.

Quelle: The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2025 Nov; Vol. 170 (5), pp. 1254-1268.e7. Date of Electronic Publication: 2025 Jun 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mosby Country of Publication: United States NLM ID: 0376343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-685X (Electronic) Linking ISSN: 00225223 NLM ISO Abbreviation: J Thorac Cardiovasc Surg Subsets: MEDLINE

MeSH-Schlagworte: Lung Neoplasms*/pathology , Lung Neoplasms*/mortality , Lung Neoplasms*/surgery , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/mortality , Adenocarcinoma of Lung*/surgery , Adenocarcinoma of Lung*/genetics , Adenocarcinoma of Lung*/metabolism , Mucins*/metabolism , Mucins*/analysis, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Prognosis ; Risk Assessment ; Risk Factors ; Pneumonectomy

Cryptosporidium dense granule effector MUC5 interacts with host actin cytoskeleton through CD2AP.

Autoren: Ao Y Yang F Li J et al.

Quelle: Microbiological research [Microbiol Res] 2025 Nov; Vol. 300, pp. 128284. Date of Electronic Publication: 2025 Jul 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH-Schlagworte: Protozoan Proteins*/metabolism , Protozoan Proteins*/genetics , Actin Cytoskeleton*/metabolism , Cryptosporidium parvum*/pathogenicity , Cryptosporidium parvum*/metabolism , Cryptosporidium parvum*/genetics , Mucins*/metabolism , Mucins*/genetics , GTPase-Activating Proteins*/metabolism, Humans ; Animals ; Host-Parasite Interactions ; Cryptosporidiosis/parasitology ; Host-Pathogen Interactions ; Cytoskeletal Proteins ; Adaptor Proteins, Signal Transducing

Chemical Variability and Biological Potential of Cornu aspersum Mucus as a Source for the Development of New Cosmetic and Pharmaceutical Products.

Autoren: Hudz N Turkina V Alyokhina T et al.

Quelle: Molecules (Basel, Switzerland) [Molecules] 2025 Oct 27; Vol. 30 (21). Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH-Schlagworte: Mucus*/chemistry , Cosmetics*/chemistry , Cosmetics*/pharmacology , Snails*/chemistry , Mucins*/chemistry , Mucins*/pharmacology, Animals ; Humans ; Wound Healing/drug effects ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemistry ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/chemistry

Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins.

Autoren: Jaroentomeechai T Veloz B Soares CO et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 13; Vol. 16 (1), pp. 9058. Date of Electronic Publication: 2025 Oct 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Mucins*/metabolism , Mucins*/chemistry , Polysaccharides*/metabolism , Polysaccharides*/chemistry, Humans ; Protein Binding ; Microbiota ; Bacterial Adhesion ; Monosaccharides/metabolism ; Monosaccharides/chemistry

Molecular mechanisms and pathophysiological implications of mucin-type O-glycosylation dysregulation in colorectal cancer progression.

Autoren: Jankowski WM Fichna J Tarasiuk-Zawadzka A

Quelle: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Oct; Vol. 398 (10), pp. 13049-13063. Date of Electronic Publication: 2025 Apr 21.

Publikationsart: Journal Article; Systematic Review; Review

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/pathology , Mucins*/metabolism, Humans ; Glycosylation ; Disease Progression ; Animals

Investigation of competitive binding of the essential trace elements zinc, iron, copper, and manganese by gastrointestinal mucins and the effect on their absorption in vitro.

Autoren: Maares M Einhorn V Behrendt J et al.

Quelle: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Oct; Vol. 144, pp. 109983. Date of Electronic Publication: 2025 Jun 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

MeSH-Schlagworte: Trace Elements*/metabolism , Intestinal Absorption* , Mucins*/metabolism, Animals ; Humans ; Zinc/metabolism ; Manganese/metabolism ; Copper/metabolism ; Iron/metabolism ; Caco-2 Cells ; Swine ; Binding, Competitive ; HT29 Cells ; Intestinal Mucosa/metabolism

Foot-and-mouth disease virus alters MUC genes expression and function of goblet cells in the intestines of naturally infected cattle calves.

Autoren: Sahoo M Singh R Patel S et al.

Quelle: Microbial pathogenesis [Microb Pathog] 2025 Oct; Vol. 207, pp. 107952. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1208 (Electronic) Linking ISSN: 08824010 NLM ISO Abbreviation: Microb Pathog Subsets: MEDLINE

MeSH-Schlagworte: Goblet Cells*/virology , Goblet Cells*/pathology , Goblet Cells*/metabolism , Mucins*/genetics , Mucins*/metabolism , Foot-and-Mouth Disease*/pathology , Foot-and-Mouth Disease*/virology , Cattle Diseases*/virology , Cattle Diseases*/pathology , Foot-and-Mouth Disease Virus*/pathogenicity , Intestines*/pathology , Intestines*/virology, Animals ; Cattle ; Lymph Nodes/pathology ; Lymph Nodes/virology ; Intestinal Mucosa/pathology ; Intestinal Mucosa/virology ; Intestine, Small/pathology ; Intestine, Small/virology ; Gene Expression

Synthesis of the O-linked pentasaccharide from Trypanosoma cruzi mucins containing the β-D-Galf-(1→2)-β-D-Galf motif.

Autoren: Cori CR Altaleff L Kashiwagi GA et al.

Quelle: Carbohydrate research [Carbohydr Res] 2025 Oct; Vol. 556, pp. 109598. Date of Electronic Publication: 2025 Jul 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0043535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-426X (Electronic) Linking ISSN: 00086215 NLM ISO Abbreviation: Carbohydr Res Subsets: MEDLINE

MeSH-Schlagworte: Trypanosoma cruzi*/chemistry , Mucins*/chemistry , Oligosaccharides*/chemistry , Oligosaccharides*/chemical synthesis, Carbohydrate Sequence ; Glycosylation

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O-Glycan Degradation and Pathogenicity in a Potentially Multidrug-Resistant Clostridium tertium Strain.

Autoren: Kim S Kang JY Lee JS

Quelle: MicrobiologyOpen [Microbiologyopen] 2025 Dec; Vol. 14 (6), pp. e70169.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101588314 Publication Model: Print Cited Medium: Internet ISSN: 2045-8827 (Electronic) Linking ISSN: 20458827 NLM ISO Abbreviation: Microbiologyopen Subsets: MEDLINE

MeSH-Schlagworte: Mucins*/metabolism , Virulence Factors*/genetics , Polysaccharides*/metabolism , Clostridium*/genetics , Clostridium*/pathogenicity , Clostridium*/isolation & purification , Clostridium*/metabolism , Clostridium*/drug effects , Clostridium*/classification , Drug Resistance, Multiple, Bacterial*/genetics, Humans ; Genome, Bacterial ; Genomics ; Feces/microbiology ; Virulence/genetics ; Phylogeny