Suchergebnisse - "MITOGEN-activated protein kinases"

OTSSP167 suppresses TNBC brain metastasis via ROS-driven P38/JNK and FAK/ERK pathways.

Autoren: Tang D Xu C Jiang Z et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 05; Vol. 1004, pp. 178017. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Reactive Oxygen Species*/metabolism , Brain Neoplasms*/secondary , Brain Neoplasms*/drug therapy , Brain Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/metabolism , p38 Mitogen-Activated Protein Kinases*/metabolism , MAP Kinase Signaling System*/drug effects , Focal Adhesion Kinase 1*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use, Animals ; Humans ; Cell Line, Tumor ; Mice ; Cell Proliferation/drug effects ; Female ; Apoptosis/drug effects ; Cell Movement/drug effects ; Xenograft Model Antitumor Assays ; JNK Mitogen-Activated Protein Kinases/metabolism

Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling.

Autoren: Mizuno S Kurobe-Takashima Y Kuriki D et al.

Quelle: PloS one [PLoS One] 2025 Jul 28; Vol. 20 (7), pp. e0328206. Date of Electronic Publication: 2025 Jul 28 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/drug effects , Microglia*/metabolism , Lipopolysaccharides*/pharmacology , NF-kappa B*/metabolism , Phosphatidylcholines*/pharmacology , p38 Mitogen-Activated Protein Kinases*/metabolism , Inflammation*/metabolism , Inflammation*/drug therapy , MAP Kinase Signaling System*/drug effects , Anti-Inflammatory Agents*/pharmacology, Animals ; Mice ; Cell Line ; Signal Transduction/drug effects ; JNK Mitogen-Activated Protein Kinases/metabolism ; Phosphorylation/drug effects ; Cytokines/metabolism

Jiawei Erzhiwan Ameliorates Androgenetic Alopecia by Regulating the SIRT1/JNK/p38 MAPK Pathway.

Autoren: Huang Z Li Y Xie Y et al.

Quelle: Drug design, development and therapy [Drug Des Devel Ther] 2025 Apr 01; Vol. 19, pp. 2393-2409. Date of Electronic Publication: 2025 Apr 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

MeSH-Schlagworte: Sirtuin 1*/metabolism , Sirtuin 1*/antagonists & inhibitors , Alopecia*/drug therapy , Alopecia*/metabolism , Alopecia*/chemically induced , Alopecia*/pathology , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/antagonists & inhibitors , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/chemistry , MAP Kinase Signaling System*/drug effects, Animals ; Mice ; Dose-Response Relationship, Drug ; Male ; Disease Models, Animal ; Mice, Inbred C57BL ; Cells, Cultured ; JNK Mitogen-Activated Protein Kinases/metabolism ; Dihydrotestosterone ; Structure-Activity Relationship

Berberine hydrochloride enhances innate immunity to protect against pathogen infection via p38 MAPK pathway.

Autoren: Xiao Y Cui Y Zhang Y et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Feb 28; Vol. 16, pp. 1536143. Date of Electronic Publication: 2025 Feb 28 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Berberine*/pharmacology , Immunity, Innate*/drug effects , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/immunology , MAP Kinase Signaling System*/drug effects , MAP Kinase Signaling System*/immunology, Animals ; Mice ; Caenorhabditis elegans/immunology ; Caenorhabditis elegans Proteins/metabolism ; Pseudomonas aeruginosa/immunology ; Listeria monocytogenes/immunology ; Mitogen-Activated Protein Kinases

RG108 attenuates acute kidney injury by inhibiting P38 MAPK/FOS and JNK/JUN pathways.

Autoren: Kong FX Liu H Xu T et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt A), pp. 113077. Date of Electronic Publication: 2024 Sep 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Acute Kidney Injury*/drug therapy , Acute Kidney Injury*/metabolism , Acute Kidney Injury*/pathology , Cisplatin* , p38 Mitogen-Activated Protein Kinases*/metabolism, Animals ; Humans ; Male ; Mice ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; JNK Mitogen-Activated Protein Kinases/metabolism ; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Kidney/pathology ; Kidney/drug effects ; Kidney/metabolism ; MAP Kinase Signaling System/drug effects ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-fos/metabolism ; Proto-Oncogene Proteins c-fos/genetics ; Phthalimides ; Tryptophan/analogs & derivatives

Rhein Alleviates Doxorubicin-Induced Myocardial Injury by Inhibiting the p38 MAPK/HSP90/c-Jun/c-Fos Pathway-Mediated Apoptosis.

Autoren: Chen Y Tu Y Cao J et al.

Quelle: Cardiovascular toxicology [Cardiovasc Toxicol] 2024 Nov; Vol. 24 (11), pp. 1139-1150. Date of Electronic Publication: 2024 Sep 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 101135818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0259 (Electronic) Linking ISSN: 15307905 NLM ISO Abbreviation: Cardiovasc Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Doxorubicin* , Apoptosis*/drug effects , Anthraquinones*/pharmacology , Cardiotoxicity* , p38 Mitogen-Activated Protein Kinases*/metabolism , Disease Models, Animal* , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/pathology , Myocytes, Cardiac*/metabolism , Proto-Oncogene Proteins c-jun*/metabolism , Proto-Oncogene Proteins c-jun*/genetics , HSP90 Heat-Shock Proteins*/metabolism , HSP90 Heat-Shock Proteins*/genetics , Mice, Inbred C57BL* , Proto-Oncogene Proteins c-fos*/metabolism , Proto-Oncogene Proteins c-fos*/genetics , Signal Transduction*, Animals ; Male ; JNK Mitogen-Activated Protein Kinases/metabolism ; Ventricular Function, Left/drug effects ; Mice ; Apoptosis Regulatory Proteins/metabolism ; Apoptosis Regulatory Proteins/genetics ; Heart Diseases/chemically induced ; Heart Diseases/prevention & control ; Heart Diseases/pathology ; Heart Diseases/metabolism ; Protein Interaction Maps

[Mechanism of protective effect of metformin against septic cardiomyopathy based on the P38 MAPK/JNK signaling pathway].

Autoren: Li L Liao Y Liu ZY

Quelle: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] [Zhonghua Yu Fang Yi Xue Za Zhi] 2024 Oct 06; Vol. 58 (10), pp. 1567-1572.

Publikationsart: English Abstract; Journal Article

Info zur Zeitschrift: Publisher: Zhonghua yi xue hui Country of Publication: China NLM ID: 7904962 Publication Model: Print Cited Medium: Print ISSN: 0253-9624 (Print) Linking ISSN: 02539624 NLM ISO Abbreviation: Zhonghua Yu Fang Yi Xue Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Metformin*/pharmacology , Mice, Inbred C57BL* , p38 Mitogen-Activated Protein Kinases*/metabolism , Cardiomyopathies*/drug therapy , Cardiomyopathies*/metabolism , MAP Kinase Signaling System*/drug effects , Disease Models, Animal*, Animals ; Mice ; Female ; Sepsis/drug therapy ; Sepsis/metabolism ; JNK Mitogen-Activated Protein Kinases/metabolism ; Apoptosis/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Signal Transduction/drug effects

Dendrobine Ameliorates Glucocorticoid-Induced Osteoporosis by Promoting Osteogenesis through JNK/p38 MAPK Pathway Activation and GR Nuclear Translocation Inhibition.

Autoren: Li X Gao C Zhou K et al.

Quelle: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Jul 31; Vol. 72 (30), pp. 16739-16748. Date of Electronic Publication: 2024 Jul 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Glucocorticoids*/adverse effects , Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/metabolism , Osteogenesis*/drug effects , Osteoporosis*/drug therapy , Osteoporosis*/metabolism , Osteoporosis*/chemically induced , Osteoporosis*/prevention & control , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/genetics , Rats, Sprague-Dawley*, Animals ; Humans ; Male ; Rats ; Cell Differentiation/drug effects ; Dexamethasone/adverse effects ; JNK Mitogen-Activated Protein Kinases/metabolism ; JNK Mitogen-Activated Protein Kinases/genetics ; MAP Kinase Signaling System/drug effects ; Plant Extracts/pharmacology ; Receptors, Glucocorticoid/metabolism ; Receptors, Glucocorticoid/genetics

Investigating the Roles of MAPKs as Precision Oncology Targets: A Multi-cancer Expression and Survival Study.

Autoren: Sulaimani MN Singh P Saeed MU et al.

Quelle: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2025 Nov-Dec; Vol. 22 (6), pp. 1006-1024.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium: Internet ISSN: 1790-6245 (Electronic) Linking ISSN: 11096535 NLM ISO Abbreviation: Cancer Genomics Proteomics Subsets: MEDLINE

MeSH-Schlagworte: Neoplasms*/genetics , Neoplasms*/mortality , Neoplasms*/pathology , Neoplasms*/drug therapy , Mitogen-Activated Protein Kinases*/genetics , Mitogen-Activated Protein Kinases*/metabolism , Biomarkers, Tumor*/genetics, Humans ; Precision Medicine/methods ; Gene Expression Regulation, Neoplastic ; Tumor Microenvironment ; Gene Expression Profiling ; Prognosis

Deubiquitinating enzyme USP42 promotes breast cancer progression by inhibiting JNK/p38-mediated apoptosis.

Autoren: He C Chen J Tian R et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 21; Vol. 15 (1), pp. 36751. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Breast Neoplasms*/genetics , Apoptosis* , p38 Mitogen-Activated Protein Kinases*/metabolism , MAP Kinase Signaling System* , Ubiquitin Thiolesterase*/metabolism , Ubiquitin Thiolesterase*/genetics , JNK Mitogen-Activated Protein Kinases*/metabolism, Humans ; Female ; Animals ; Cell Proliferation ; Mice ; Mice, Nude ; Disease Progression ; Cell Line, Tumor ; MCF-7 Cells ; Gene Expression Regulation, Neoplastic ; Middle Aged

GPR124 promotes trophoblast proliferation, migration, and invasion and inhibits trophoblast cell apoptosis and inflammation via JNK and P38 MAPK pathways.

Autoren: Shen Y Lian Y Xiao L et al.

Quelle: Journal of cellular physiology [J Cell Physiol] 2024 Aug; Vol. 239 (8), pp. e31298. Date of Electronic Publication: 2024 May 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

MeSH-Schlagworte: Trophoblasts*/metabolism , Trophoblasts*/pathology , Apoptosis*/genetics , Cell Proliferation*/genetics , Cell Movement*/genetics , Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/genetics , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/genetics , Pre-Eclampsia*/pathology , Pre-Eclampsia*/genetics , Pre-Eclampsia*/metabolism , Inflammation*/pathology , Inflammation*/genetics , Inflammation*/metabolism, Humans ; Female ; Pregnancy ; MAP Kinase Signaling System ; Cell Line ; JNK Mitogen-Activated Protein Kinases/metabolism ; Placenta/metabolism ; Placenta/pathology ; Receptors, Estrogen

GmMEKK2 Disrupts the MKK1/2-MPK4 Cascade to Amplify Immune Signalling and Confer Enhanced Resistance to Soybean Mosaic Virus.

Autoren: Zhong X Luo J Ruan Y et al.

Quelle: Molecular plant pathology [Mol Plant Pathol] 2025 Dec; Vol. 26 (12), pp. e70184.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science in collaboration with the British Society of Plant Pathology Country of Publication: England NLM ID: 100954969 Publication Model: Print Cited Medium: Internet ISSN: 1364-3703 (Electronic) Linking ISSN: 13643703 NLM ISO Abbreviation: Mol Plant Pathol Subsets: MEDLINE

MeSH-Schlagworte: Glycine max*/virology , Glycine max*/immunology , Glycine max*/genetics , Disease Resistance*/genetics , Plant Diseases*/virology , Plant Diseases*/immunology , Plant Diseases*/genetics , Potyvirus*/pathogenicity , Potyvirus*/physiology , Plant Proteins*/metabolism , Plant Proteins*/genetics , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/genetics, Gene Expression Regulation, Plant ; Plants, Genetically Modified ; MAP Kinase Signaling System ; Signal Transduction

SCR Organism: Soybean mosaic virus

Appropriate doses of ionizing radiation facilitate the proliferation and anti-tumor effects of γδ T cells through ERK and p38MAPK pathways in vitro.

Autoren: Wang LL Yang Y Feng YB et al.

Quelle: Molecular immunology [Mol Immunol] 2025 Dec; Vol. 188, pp. 80-88. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9142 (Electronic) Linking ISSN: 01615890 NLM ISO Abbreviation: Mol Immunol Subsets: MEDLINE

MeSH-Schlagworte: Cell Proliferation*/radiation effects , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/immunology , Receptors, Antigen, T-Cell, gamma-delta*/immunology , Receptors, Antigen, T-Cell, gamma-delta*/metabolism , MAP Kinase Signaling System*/radiation effects , MAP Kinase Signaling System*/immunology , Radiation, Ionizing* , T-Lymphocytes*/immunology , T-Lymphocytes*/radiation effects, Humans ; Granzymes/metabolism ; Dose-Response Relationship, Radiation ; Interferon-gamma/metabolism

Ca ²⁺ , ROS, IL-6, and p38 MAPK signaling loops underlying alterations in myotube formation induced by a severe MH/CCD mutation in RyR1.

Autoren: Valle-Clara M Ávila G

Quelle: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2025 Dec 01; Vol. 329 (6), pp. C1880-C1893. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

MeSH-Schlagworte: Ryanodine Receptor Calcium Release Channel*/genetics , Ryanodine Receptor Calcium Release Channel*/metabolism , Interleukin-6*/metabolism , Interleukin-6*/genetics , Muscle Fibers, Skeletal*/metabolism , Muscle Fibers, Skeletal*/pathology , Reactive Oxygen Species*/metabolism , Calcium*/metabolism , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/genetics , Mutation*/genetics , Myopathies, Structural, Congenital*/genetics , Myopathies, Structural, Congenital*/pathology , Myopathies, Structural, Congenital*/metabolism , Myopathy, Central Core*/genetics , Myopathy, Central Core*/metabolism , Myopathy, Central Core*/pathology, Animals ; Mice ; Humans ; Sarcoplasmic Reticulum/metabolism ; Calcium Signaling

Design and synthesis of novel pyrimidine-pyrazole hybrids with dual anticancer and anti-inflammatory effects targeting BRAFV600E and JNK.

Autoren: Abdel-Maksoud MS Eitah HE Hassan RM et al.

Quelle: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6205-6225. Date of Electronic Publication: 2025 Feb 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Pyrazoles*/chemistry , Pyrazoles*/pharmacology , Pyrazoles*/chemical synthesis , Proto-Oncogene Proteins B-raf*/genetics , Proto-Oncogene Proteins B-raf*/antagonists & inhibitors , Proto-Oncogene Proteins B-raf*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/chemical synthesis , Pyrimidines*/chemistry , Pyrimidines*/pharmacology , Pyrimidines*/chemical synthesis , Drug Design* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , JNK Mitogen-Activated Protein Kinases*/antagonists & inhibitors , JNK Mitogen-Activated Protein Kinases*/metabolism, Humans ; Mice ; Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; RAW 264.7 Cells ; Structure-Activity Relationship

Pmk1 as a target for both protective and curative treatments against pathogenic fungi.

Autoren: Kong Z Feng J Li J et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 332 (Pt 2), pp. 148664. Date of Electronic Publication: 2025 Nov 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Fungicides, Industrial*/pharmacology , Fungicides, Industrial*/chemistry , Fungal Proteins*/antagonists & inhibitors , Fungal Proteins*/chemistry , Fungal Proteins*/metabolism , Mitogen-Activated Protein Kinases*/antagonists & inhibitors , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/chemistry , Ascomycota*/drug effects , Ascomycota*/pathogenicity , Ascomycota*/enzymology, Plant Diseases/microbiology ; Plant Diseases/prevention & control ; Oryza/microbiology ; Hyphae/drug effects ; Molecular Docking Simulation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry

SCR Organism: Pyricularia oryzae

Hemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK.

Autoren: Cheng J Shi Y Kong Y et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2546066. Date of Electronic Publication: 2025 Aug 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Hemolymph*/microbiology , Hemolymph*/immunology , Hemocyanins*/metabolism , Hemocyanins*/genetics , Reactive Oxygen Species*/metabolism , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/genetics , Vibrio* , Penaeidae*/microbiology , Penaeidae*/immunology, Animals ; Hemocytes/microbiology ; Hemocytes/immunology ; Hemocytes/metabolism ; Oxidation-Reduction ; MAP Kinase Signaling System ; Antioxidants/metabolism

Mitogen-Activated Protein Kinase Driven Rare Gynecologic Cancers and Evolving Therapeutic Targets.

Autoren: Grisham RN Praiss A Kyi C et al.

Quelle: Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2025 Dec; Vol. 39 (6), pp. 1101-1110.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Health Science Country of Publication: United States NLM ID: 8709473 Publication Model: Print Cited Medium: Internet ISSN: 1558-1977 (Electronic) Linking ISSN: 08898588 NLM ISO Abbreviation: Hematol Oncol Clin North Am Subsets: MEDLINE

MeSH-Schlagworte: Genital Neoplasms, Female*/drug therapy , Genital Neoplasms, Female*/metabolism , Genital Neoplasms, Female*/genetics , Genital Neoplasms, Female*/enzymology , MAP Kinase Signaling System*/drug effects , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/metabolism , Ovarian Neoplasms*/enzymology , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/genetics, Humans ; Female ; Molecular Targeted Therapy ; Protein Kinase Inhibitors/therapeutic use

L1CAM enhances autophagy via inhibition of p38 phosphorylation in colorectal cancer development and progression.

Autoren: Hu X Wu T Xie Y et al.

Quelle: Genes & genomics [Genes Genomics] 2025 Dec; Vol. 47 (12), pp. 1333-1342. Date of Electronic Publication: 2025 Nov 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: The Korean Society of Genetics Country of Publication: Korea (South) NLM ID: 101481027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-9293 (Electronic) Linking ISSN: 19769571 NLM ISO Abbreviation: Genes Genomics Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics , Autophagy*/genetics , p38 Mitogen-Activated Protein Kinases*/metabolism , p38 Mitogen-Activated Protein Kinases*/genetics , Neural Cell Adhesion Molecule L1*/metabolism , Neural Cell Adhesion Molecule L1*/genetics, Humans ; Phosphorylation ; Cell Proliferation/genetics ; Apoptosis/genetics ; Cell Line, Tumor ; HT29 Cells ; Disease Progression

The Hog1-Nmd5 signaling pathway regulates asexual development, lipid metabolism, stress response, trap morphogenesis, and secondary metabolism of Arthrobotrys oligospora .

Autoren: Zhao N Liu Q Zhu M et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2468294. Date of Electronic Publication: 2025 Feb 19.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Lipid Metabolism* , Fungal Proteins*/metabolism , Fungal Proteins*/genetics , Signal Transduction* , Ascomycota*/genetics , Ascomycota*/growth & development , Ascomycota*/metabolism , Ascomycota*/physiology , Mitogen-Activated Protein Kinases*/metabolism , Mitogen-Activated Protein Kinases*/genetics, Secondary Metabolism ; Animals ; Gene Expression Regulation, Fungal ; Stress, Physiological ; Nematoda/microbiology ; Spores, Fungal/growth & development ; Reproduction, Asexual

SCR Organism: Arthrobotrys oligospora